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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9947 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Targeting the unfolded protein response components differentially sensitizes breast tumors to doxorubicin while modulating chemotherapy-induced cardiotoxicities [abstract]

Authors:
Soto-Pantoja D, Clear K, Cook KL
Citation:
Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P5-14-19. doi:10.1158/1538-7445.SABCS19-P5-14-19
Abstract:
Background: The unfolded protein response (UPR) is an endoplasmic reticulum pathway stimulated when the protein folding demand...
Organism or Cell Type:
mouse xenograft 4T1-luciferase triple negative breast cancer cells
Citation Extract:
Soto-Pantoja D, Clear K, Cook KL. Targeting the unfolded protein response components differentially sensitizes breast tumors to doxorubicin while modulating chemotherapy-induced cardiotoxicities [abstract]. Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P5-14-19. doi:10.1158/1538-7445.SABCS19-P5-14-19.

Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site

Authors:
Smith SJ, Towers N, Demetriou K, Mohun TJ
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.13.947424
Abstract:
ADP-ribosylhydrolase-like 1 (Adprhl1) is a pseudoenzyme expressed in the developing heart myocardium of all vertebrates. In the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Smith SJ, Towers N, Demetriou K, Mohun TJ. Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.13.947424.

Diastereoselective Synthesis of Phosphorodiamidate Morpholino Dimers

Authors:
Min SJ, Kim NY, Chae HY, Chun KH
Citation:
Bull Korean Chem Soc. 2020. doi:10.1002/bkcs.11958
Abstract:
No abstract available.
Citation Extract:
Min SJ, Kim NY, Chae HY, Chun KH. Diastereoselective Synthesis of Phosphorodiamidate Morpholino Dimers. Bull Korean Chem Soc. 2020. doi:10.1002/bkcs.11958.

Photoreceptor progenitor dynamics in the zebrafish embryo retina and its modulation by primary cilia and N-cadherin

Authors:
Aparicio G, Rodao M, Badano JL, Zolessi FR
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.13.947663
Abstract:
Background: Photoreceptors of the vertebrate neural retina are originated from the neuroepithelium, and like other neurons,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Aparicio G, Rodao M, Badano JL, Zolessi FR. Photoreceptor progenitor dynamics in the zebrafish embryo retina and its modulation by primary cilia and N-cadherin. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.13.947663 .

Zebrafish Pax1a and Pax1b are required for pharyngeal pouch morphogenesis and ceratobranchial cartilage development

Authors:
Liu YH, Lin TC, Hwang SL
Citation:
Mech Dev. 2020 Feb 13:103598. doi: 10.1016/j.mod.2020.103598. [Epub ahead of print]
Abstract:
Pharyngeal arches are derived from all three germ layers and molecular interactions among the tissue types are required for...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu YH, Lin TC, Hwang SL. Zebrafish Pax1a and Pax1b are required for pharyngeal pouch morphogenesis and ceratobranchial cartilage development. Mech Dev. 2020 Feb 13:103598. doi: 10.1016/j.mod.2020.103598. [Epub ahead of print].

Triazine-cored polymeric vectors for antisense oligonucleotide delivery in vitro and in vivo

Authors:
Wang M, Wu B, Tucker JD, Shah SN, Lu P, Lu Q
Citation:
J Nanobiotechnology. 2020 Feb 18;18(1):34. doi: 10.1186/s12951-020-0586-8
Abstract:
BACKGROUND: The polymer-based drug/gene delivery is promising for the treatment of inherent or acquire disease, because of the...
Delivery Method:
triazine-cored amphiphilic polymers (TAPs)
Organism or Cell Type:
cell culture: C2C12E50 myoblast & C2C12E23 differentiated cells, mice mdx
Citation Extract:
Wang M, Wu B, Tucker JD, Shah SN, Lu P, Lu Q. Triazine-cored polymeric vectors for antisense oligonucleotide delivery in vitro and in vivo. J Nanobiotechnology. 2020 Feb 18;18(1):34. doi: 10.1186/s12951-020-0586-8.

Estrogen acts via estrogen receptor 2b to regulate hepatobiliary fate during vertebrate development

Authors:
Chaturantabut S, Shwartz A, Garnaas MK, LaBella K, Li CC, Carroll KJ, Cutting CC, Budrow N, Palaria A, Gorelick DA, Tremblay KD, North TE, Goessling W
Citation:
Hepatology. 2020 Feb 14. doi: 10.1002/hep.31184. [Epub ahead of print]
Abstract:
During liver development bipotent progenitor cells differentiate into hepatocytes and biliary epithelial cells (BECs) to ensure...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chaturantabut S, Shwartz A, Garnaas MK, LaBella K, Li CC, Carroll KJ, Cutting CC, Budrow N, Palaria A, Gorelick DA, Tremblay KD, North TE, Goessling W. Estrogen acts via estrogen receptor 2b to regulate hepatobiliary fate during vertebrate development. Hepatology. 2020 Feb 14. doi: 10.1002/hep.31184. [Epub ahead of print].

NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and Xenopus laevis models

Authors:
Singh MD, Jensen M, Lasser M, Huber E, Yusuff T, Pizzo L, Lifschutz B, Desai I, Kubina A, Yennawar S, Kim S, Iyer J, Rincon-Limas DE, Lowery LA, Girirajan S
Citation:
PLoS Genet. 2020;16(2):e1008590. doi:10.1371/journal.pgen.1008590
Abstract:
The 1.6 Mbp deletion on chromosome 3q29 is associated with a range of neurodevelopmental disorders, including schizophrenia,...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Singh MD, Jensen M, Lasser M, Huber E, Yusuff T, Pizzo L, Lifschutz B, Desai I, Kubina A, Yennawar S, Kim S, Iyer J, Rincon-Limas DE, Lowery LA, Girirajan S. NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and Xenopus laevis models. PLoS Genet. 2020;16(2):e1008590. doi:10.1371/journal.pgen.1008590.

CRISPR-Cas13d induces efficient mRNA knock-down in animal embryos

Authors:
Kushawah G, del Prado JA-N, Martinez-Morales JR, DeVore M, Guelfo JR, Brannan EO, Wang W, Corbin TJ, Moran AM, Alvarado AS, Málaga-Trillo E, Takacs CM, Bazzini AA, Moreno-Mateos MA
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.01.13.904763
Abstract:
Early embryonic development is driven exclusively by maternal gene products deposited into the oocyte. Although critical in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kushawah G, del Prado JA-N, Martinez-Morales JR, DeVore M, Guelfo JR, Brannan EO, Wang W, Corbin TJ, Moran AM, Alvarado AS, Málaga-Trillo E, Takacs CM, Bazzini AA, Moreno-Mateos MA. CRISPR-Cas13d induces efficient mRNA knock-down in animal embryos. bioRxiv. 2020;[preprint] doi:10.1101/2020.01.13.904763.

Cancer-associated HIF-2α impacts trunk neural crest stemness

Authors:
Mohlin S, Persson CU, Fredlund E, Monni E, Lindvall JM, Kokaia Z, Hammarlund E, Bronner ME
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.01.22.915199
Abstract:
The neural crest is a stem cell population that gives rise to sympathetic ganglia, the cell type of origin of neuroblastoma....
Delivery Method:
injection then electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Mohlin S, Persson CU, Fredlund E, Monni E, Lindvall JM, Kokaia Z, Hammarlund E, Bronner ME. Cancer-associated HIF-2α impacts trunk neural crest stemness. bioRxiv. 2020;[preprint] doi:10.1101/2020.01.22.915199.

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