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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9382 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Vegfa/vegfr2 signaling is necessary for zebrafish islet vessel development, but is dispensable for beta-cell and alpha-cell formation

Authors:
Toselli CM, Wilkinson BM, Paterson J, Kieffer TJ
Citation:
Sci Rep. 2019 Mar 5;9(1):3594. doi: 10.1038/s41598-019-40136-1
Abstract:
The mechanisms underlying zebrafish pancreatic islet vascularization have not been well characterized. We sought to determine...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Toselli CM, Wilkinson BM, Paterson J, Kieffer TJ. Vegfa/vegfr2 signaling is necessary for zebrafish islet vessel development, but is dispensable for beta-cell and alpha-cell formation. Sci Rep. 2019 Mar 5;9(1):3594. doi: 10.1038/s41598-019-40136-1.

Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1

Authors:
Poganik JR, Long MJC, Disare MT, Liu X, Chang S-H, Hla T, Aye Y
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/565937
Abstract:
The Nrf2-driven antioxidant response (AR) is a target of covalent drugs and bioactive native electrophiles. However, much of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Poganik JR, Long MJC, Disare MT, Liu X, Chang S-H, Hla T, Aye Y. Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1. bioRxiv. 2019;[preprint] doi:10.1101/565937.

A novel L1CAM isoform with angiogenic activity generated by NOVA2-mediated alternative splicing

Authors:
Angiolini F, Belloni E, Giordano M, Campioni M, Forneris F, Paola PM, Lupia M, Brandas C, Pradella D, Di Matteo A, Giampietro C, Jodice G, Luise C, Bertalot G, Freddi S, Malinverno M, Irimia M, Moulton JD, Summerton J, Chiapparino A, Ghilardi C, Giavazzi R, Nyqvist D, Gabellini D, Dejana E, Cavallaro U, Ghigna C
Citation:
Elife. 2019 Mar 4;8. pii: e44305. doi: 10.7554/eLife.44305
Abstract:
The biological players involved in angiogenesis are only partially defined. Here, we report that endothelial cells (ECs)...
Delivery Method:
Endo-Porter PEG
Organism or Cell Type:
cell culture: mouse lu2EC
Citation Extract:
Angiolini F, Belloni E, Giordano M, Campioni M, Forneris F, Paola PM, Lupia M, Brandas C, Pradella D, Di Matteo A, Giampietro C, Jodice G, Luise C, Bertalot G, Freddi S, Malinverno M, Irimia M, Moulton JD, Summerton J, Chiapparino A, Ghilardi C, Giavazzi R, Nyqvist D, Gabellini D, Dejana E, Cavallaro U, Ghigna C. A novel L1CAM isoform with angiogenic activity generated by NOVA2-mediated alternative splicing. Elife. 2019 Mar 4;8. pii: e44305. doi: 10.7554/eLife.44305.

TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy

Authors:
Yang RM, Tao J, Zhan M, Yuan H, Wang HH, Chen SJ, Zhu C, de Thé H, Zhou J, Guo Y, Zhu J
Citation:
Cell Death Differ. 2019 Mar 1. doi: 10.1038/s41418-019-0311-z. [Epub ahead of print]
Abstract:
TAMM41, located within the congenital heart diseases (CHD) sensitive region of 3p25 deletion syndrome, is a mitochondrial...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang RM, Tao J, Zhan M, Yuan H, Wang HH, Chen SJ, Zhu C, de Thé H, Zhou J, Guo Y, Zhu J. TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy. Cell Death Differ. 2019 Mar 1. doi: 10.1038/s41418-019-0311-z. [Epub ahead of print].

Exon-mediated activation of transcription starts

Authors:
Fiszbein A, Krick KS, Burge CB
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/565184
Abstract:
The processing of transcripts from mammalian genes often occurs near in time and space to their transcription. Here we...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: mouse fibroblasts
Citation Extract:
Fiszbein A, Krick KS, Burge CB. Exon-mediated activation of transcription starts. bioRxiv. 2019;[preprint] doi:10.1101/565184.

GRIK5 Genetically Regulated Expression Associated with Eye and Vascular Phenomes: Discovery through Iteration among Biobanks, Electronic Health Records, and Zebrafish

Authors:
Unlu G, Gamazon ER, Qi X, Levic DS, Bastarache L, Denny JC, Roden DM, Mayzus I, Breyer M, Zhong X, Konkashbaev AI, Rzhetsky A, Knapik EW, Cox NJ
Citation:
Am J Hum Genet. 2019 Feb 27. pii: S0002-9297(19)30017-5. doi: 10.1016/j.ajhg.2019.01.017. [Epub ahead of print]
Abstract:
Although the use of model systems for studying the mechanism of mutations that have a large effect is common, we highlight here...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Unlu G, Gamazon ER, Qi X, Levic DS, Bastarache L, Denny JC, Roden DM, Mayzus I, Breyer M, Zhong X, Konkashbaev AI, Rzhetsky A, Knapik EW, Cox NJ. GRIK5 Genetically Regulated Expression Associated with Eye and Vascular Phenomes: Discovery through Iteration among Biobanks, Electronic Health Records, and Zebrafish. Am J Hum Genet. 2019 Feb 27. pii: S0002-9297(19)30017-5. doi: 10.1016/j.ajhg.2019.01.017. [Epub ahead of print].

Evolution of nitric oxide regulation of gut function

Authors:
Yaguchi J, Yaguchi S
Citation:
Proc Nat Acad Sci USA. 2019;[Epub ahead of print] doi:10.1073/pnas.1816973116
Abstract:
Although morphologies are diverse, the common pattern in bilaterians is for passage of food in the gut to be controlled by...
Delivery Method:
microinjection
Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin)
Citation Extract:
Yaguchi J, Yaguchi S. Evolution of nitric oxide regulation of gut function. Proc Nat Acad Sci USA. 2019;[Epub ahead of print] doi:10.1073/pnas.1816973116.

The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection

Authors:
Zhang R, Varela M, Vallentgoed W, Forn-Cuni G, van der Vaart M, Meijer AH
Citation:
PLoS Pathog. 2019;15(2):e1007329. doi:10.1371/journal.ppat.1007329
Abstract:
Mycobacterial pathogens are the causative agents of chronic infectious diseases like tuberculosis and leprosy. Autophagy has...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang R, Varela M, Vallentgoed W, Forn-Cuni G, van der Vaart M, Meijer AH. The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection. PLoS Pathog. 2019;15(2):e1007329. doi:10.1371/journal.ppat.1007329.

Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain

Authors:
Yildiz O, Downes GB, Sagerström CG
Citation:
Neural Dev. 2019;14:5. doi:10.1186/s13064-019-0129-x
Abstract:
Background: Functioning of the adult nervous system depends on the establishment of neural circuits during embryogenesis. In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yildiz O, Downes GB, Sagerström CG. Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain. Neural Dev. 2019;14:5. doi:10.1186/s13064-019-0129-x.

Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependent pigment progenitors in zebrafish

Authors:
Camargo-Sosa K, Colanesi S, Müller J, Schulte-Merker S, Stemple D, Patton EE, Kelsh RN
Citation:
PLoS Genet. 2019;15(2):e1007941. doi:10.1371/journal.pgen.1007941
Abstract:
Skin pigment patterns are important, being under strong selection for multiple roles including camouflage and UV protection....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Camargo-Sosa K, Colanesi S, Müller J, Schulte-Merker S, Stemple D, Patton EE, Kelsh RN . Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependent pigment progenitors in zebrafish. PLoS Genet. 2019;15(2):e1007941. doi:10.1371/journal.pgen.1007941.

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