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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9561 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract

Authors:
Blackburn ATM, Bekheirnia N, Uma VC, Corkins ME, Xu Y, Rosenfeld JA, Bainbridge MN, Yang Y, Liu P, Madan-Khetarpal S, Delgado MR, Hudgins L, Krantz I, Rodriguez-Buritica D, Wheeler PG, Gazali LA, Mohamed Saeed Mohamed Al Shamsi A, Gomez-Ospina N, Chao HT, Mirzaa GM, Scheuerle AE, Kukolich MK, Scaglia F, Eng C, Willsey HR, Braun MC, Lamb DJ, Miller RK, Bekheirnia MR
Citation:
Genet Med. 2019 Jul 2. doi: 10.1038/s41436-019-0576-0. [Epub ahead of print]
Abstract:
PURPOSE: Haploinsufficiency of DYRK1A causes a recognizable clinical syndrome. The goal of this paper is to investigate...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Blackburn ATM, Bekheirnia N, Uma VC, Corkins ME, Xu Y, Rosenfeld JA, Bainbridge MN, Yang Y, Liu P, Madan-Khetarpal S, Delgado MR, Hudgins L, Krantz I, Rodriguez-Buritica D, Wheeler PG, Gazali LA, Mohamed Saeed Mohamed Al Shamsi A, Gomez-Ospina N, Chao HT, Mirzaa GM, Scheuerle AE, Kukolich MK, Scaglia F, Eng C, Willsey HR, Braun MC, Lamb DJ, Miller RK, Bekheirnia MR. DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract. Genet Med. 2019 Jul 2. doi: 10.1038/s41436-019-0576-0. [Epub ahead of print].

Developmentally regulated GTP-binding protein 1 modulates ciliogenesis via an interaction with Dishevelled

Authors:
Lee M, Hwang YS, Yoon J, Sun J, Harned A, Nagashima K, Daar IO
Citation:
J Cell Biol. 2019 Jul 3. pii: jcb.201811147. doi: 10.1083/jcb.201811147. [Epub ahead of print]
Abstract:
Cilia are critical for proper embryonic development and maintaining homeostasis. Although extensively studied, there are still...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Lee M, Hwang YS, Yoon J, Sun J, Harned A, Nagashima K, Daar IO. Developmentally regulated GTP-binding protein 1 modulates ciliogenesis via an interaction with Dishevelled. J Cell Biol. 2019 Jul 3. pii: jcb.201811147. doi: 10.1083/jcb.201811147. [Epub ahead of print].

Long-term treatment with eteplirsen in nonambulatory patients with Duchenne muscular dystrophy

Authors:
Alfano LN, Charleston JS, Connolly AM, Cripe L, Donoghue C, Dracker R, Dworzak J, Eliopoulos H, Frank DE, Lewis S, Lucas K, Lynch J, Milici AJ, Flynt A, Naughton E, Rodino-Klapac LR, Sahenk Z, Schnell FJ, Young GD, Mendell JR, Lowes LP
Citation:
Medicine (Baltimore). 2019 Jun;98(26):e15858. doi: 10.1097/MD.0000000000015858
Abstract:
This analysis aims to describe the outcomes of two nonambulatory patients with Duchenne muscular dystrophy (DMD) who...
Delivery Method:
i.v. infusion
Organism or Cell Type:
human
Citation Extract:
Alfano LN, Charleston JS, Connolly AM, Cripe L, Donoghue C, Dracker R, Dworzak J, Eliopoulos H, Frank DE, Lewis S, Lucas K, Lynch J, Milici AJ, Flynt A, Naughton E, Rodino-Klapac LR, Sahenk Z, Schnell FJ, Young GD, Mendell JR, Lowes LP. Long-term treatment with eteplirsen in nonambulatory patients with Duchenne muscular dystrophy. Medicine (Baltimore). 2019 Jun;98(26):e15858. doi: 10.1097/MD.0000000000015858.

Functional muscle recovery following dystrophin and myostatin exon splice modulation in aged mdx mice

Authors:
Lu-Nguyen N, Ferry A, Schnell FJ, Hanson GJ, Popplewell L, Dickson G, Malerba A
Citation:
Hum Mol Genet. 2019 Jun 10. pii: ddz125. doi: 10.1093/hmg/ddz125. [Epub ahead of print]
Abstract:
Duchenne muscular dystrophy (DMD) is a rare genetic disease affecting 1 in 3500-5000 newborn boys. It is due to mutations in...
Organism or Cell Type:
mice mdx
Citation Extract:
Lu-Nguyen N, Ferry A, Schnell FJ, Hanson GJ, Popplewell L, Dickson G, Malerba A. Functional muscle recovery following dystrophin and myostatin exon splice modulation in aged mdx mice. Hum Mol Genet. 2019 Jun 10. pii: ddz125. doi: 10.1093/hmg/ddz125. [Epub ahead of print].

STIM1 Is Required for Remodeling of the Endoplasmic Reticulum and Microtubule Cytoskeleton in Steering Growth Cones

Authors:
Pavez M, Thompson AC, Arnott HJ, Mitchell CB, D'Atri I, Don EK, Chilton JK, Scott EK, Lin JY, Young KM, Gasperini RJ, Foa L
Citation:
J Neurosci. 2019 Jun 26;39(26):5095-5114. doi: 10.1523/JNEUROSCI.2496-18.2019. Epub 2019 Apr 25
Abstract:
The spatial and temporal regulation of calcium signaling in neuronal growth cones is essential for axon guidance. In growth...
Citation Extract:
Pavez M, Thompson AC, Arnott HJ, Mitchell CB, D'Atri I, Don EK, Chilton JK, Scott EK, Lin JY, Young KM, Gasperini RJ, Foa L. STIM1 Is Required for Remodeling of the Endoplasmic Reticulum and Microtubule Cytoskeleton in Steering Growth Cones. J Neurosci. 2019 Jun 26;39(26):5095-5114. doi: 10.1523/JNEUROSCI.2496-18.2019. Epub 2019 Apr 25.

The Xenopus Nieuwkoop center and Spemann-Mangold organizer share molecular components and a requirement for maternal Wnt activity

Authors:
Vonica A, Gumbiner BM
Citation:
Dev Biol. 2007 Dec 1;312(1):90-102. Epub 2007 Oct 2
Abstract:
In Xenopus embryos, the dorso-ventral and antero-posterior axes are established by the Spemann-Mangold organizer. According to...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Vonica A, Gumbiner BM. The Xenopus Nieuwkoop center and Spemann-Mangold organizer share molecular components and a requirement for maternal Wnt activity. Dev Biol. 2007 Dec 1;312(1):90-102. Epub 2007 Oct 2.

Global analysis of polysome-associated mRNA in vesicular stomatitis virus infected cells

Authors:
Neidermyer WJ Jr, Whelan SPJ
Citation:
PLoS Pathog. 2019;15(6):e1007875. doi:10.1371/journal.ppat.1007875
Abstract:
Infection of mammalian cells with vesicular stomatitis virus (VSV) results in the inhibition of cellular translation while...
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Neidermyer WJ Jr, Whelan SPJ. Global analysis of polysome-associated mRNA in vesicular stomatitis virus infected cells. PLoS Pathog. 2019;15(6):e1007875. doi:10.1371/journal.ppat.1007875.

Hypothalamic nesfatin-1 mediates feeding behavior via MC3/4R-ERK signaling pathway after weight loss in obese Sprague-Dawley rats

Authors:
Wang Y
Citation:
Peptides. 2019 Jun 28. pii: S0196-9781(19)30038-5. doi: 10.1016/j.peptides.2019.04.007. [Epub ahead of print]
Abstract:
Nesfatin-1 is an anorexic peptide derived from nucleobindin 2 (NUCB2). An increase in hypothalamic nesfatin-1 inhibits feeding...
Delivery Method:
intracerebroventricular infusion
Organism or Cell Type:
rats
Citation Extract:
Wang Y. Hypothalamic nesfatin-1 mediates feeding behavior via MC3/4R-ERK signaling pathway after weight loss in obese Sprague-Dawley rats. Peptides. 2019 Jun 28. pii: S0196-9781(19)30038-5. doi: 10.1016/j.peptides.2019.04.007. [Epub ahead of print].

Glucocorticoid receptor-dependent induction of cripto-1 (one-eyed pinhead) inhibits zebrafish caudal fin regeneration

Authors:
Garland MA, Sengupta S, Mathew LK, Truong L, de Jong E, Piersma AH, La Du J, Tanguay RL
Citation:
Toxicol Rep. 2019 May 29;6:529-537. doi: 10.1016/j.toxrep.2019.05.013. eCollection 2019
Abstract:
We previously used a chemical genetics approach with the larval zebrafish to identify small molecule inhibitors of tissue...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Garland MA, Sengupta S, Mathew LK, Truong L, de Jong E, Piersma AH, La Du J, Tanguay RL. Glucocorticoid receptor-dependent induction of cripto-1 (one-eyed pinhead) inhibits zebrafish caudal fin regeneration. Toxicol Rep. 2019 May 29;6:529-537. doi: 10.1016/j.toxrep.2019.05.013. eCollection 2019.

Dual roles of hydrogen peroxide in promoting zebrafish renal repair and regeneration

Authors:
Chen J, Yu T, He X, Fu Y, Dai L, Wang B, Wu Y, He J, Li Y, Zhang F, Zhao J, Liu C
Citation:
Biochem Biophys Res Commun. 2019 Jun 24. pii: S0006-291X(19)31178-7. doi: 10.1016/j.bbrc.2019.06.052. [Epub ahead of print]
Abstract:
Acute renal injury (AKI) is a serious disorder of renal failure or renal damage that occurs within hours or days. At present,...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Chen J, Yu T, He X, Fu Y, Dai L, Wang B, Wu Y, He J, Li Y, Zhang F, Zhao J, Liu C. Dual roles of hydrogen peroxide in promoting zebrafish renal repair and regeneration. Biochem Biophys Res Commun. 2019 Jun 24. pii: S0006-291X(19)31178-7. doi: 10.1016/j.bbrc.2019.06.052. [Epub ahead of print].

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