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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12437 scientific papers returned from the database with the search filters currently being used below.
There are 12437 scientific papers returned from the database with the search filters currently being used below.
Microglia-Derived IL-6 Promotes Müller Glia Reprogramming and Proliferation in Zebrafish Retina Regeneration
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Citation:
Invest Ophthalmol Vis Sci. 2025 Apr 1;66(4):67. doi: 10.1167/iovs.66.4.67. PMID: 40266594; PMCID: PMC12025339 Epub:
Not Epub Abstract:
Purpose: Inflammation activates the Jak1-Stat3 signaling pathway in zebrafish Müller glia (MG), leading to their status... Delivery Method:
intravitreal injection & electroporation Organism or Cell Type:
zebrafish Citation Extract: Xu J, Li Y, Li X, Tan X, Liu L, Cao L, Xu H. Microglia-Derived IL-6 Promotes Müller Glia Reprogramming and Proliferation in Zebrafish Retina Regeneration. Invest Ophthalmol Vis Sci. 2025 Apr 1;66(4):67. doi: 10.1167/iovs.66.4.67. PMID: 40266594; PMCID: PMC12025339. |
Role of different Lyl1 transcripts in zebrafish primitive hematopoiesis
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Citation:
Yi Chuan. 2025 May;47(5):573-588. doi: 10.16288/j.yczz.24-288. PMID: 40287790 Epub:
Not Epub Abstract:
Primitive hematopoiesis is a crucial process in the organism, responsible for the transportation of oxygen and nutrients during... Link:
Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin JH, Yang TS, Zhang WQ, Liu W. Role of different Lyl1 transcripts in zebrafish primitive hematopoiesis. Yi Chuan. 2025 May;47(5):573-588. doi: 10.16288/j.yczz.24-288. PMID: 40287790. |
Two-component T-cell immunotherapy enables antigen pre-targeting to reduce cytokine release without forfeiting efficacy
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Citation:
Nanomedicine. 2025 Apr 30;67:102825. doi: 10.1016/j.nano.2025.102825. Epub ahead of print. PMID: 40316226 Epub:
Not Epub Abstract:
Contemporary T-cell immunotherapies, despite impressive targeting precision, are hindered by aberrant cytokine release and... Delivery Method:
Fab-linked; mice: intravenous (i.v.) injection Organism or Cell Type:
cell culture: Raji B-cells; mice: SCID C·B-17 Citation Extract: Gambles MT, Kendell I, Li J, Spainhower K, Sborov D, Owen S, Stark A, Bearss D, Yang J, Kopeček J. Two-component T-cell immunotherapy enables antigen pre-targeting to reduce cytokine release without forfeiting efficacy. Nanomedicine. 2025 Apr 30;67:102825. doi: 10.1016/j.nano.2025.102825. Epub ahead of print. PMID: 40316226. |
G protein-coupled receptor GPR182 negatively regulates sprouting angiogenesis via modulating CXCL12-CXCR4 axis signaling
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Citation:
Angiogenesis. 2025 May 2;28(3):25. doi: 10.1007/s10456-025-09977-5. PMID: 40314798; PMCID: PMC12048421 Epub:
Not Epub Abstract:
Angiogenesis is a critical process for tumor progression, regulated by various signaling pathways. Although antiangiogenic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen C, Liu W, Yuan F, Wang X, Xu X, Ling CC, Ge X, Shen X, Li B, Shen Y, Liu D. G protein-coupled receptor GPR182 negatively regulates sprouting angiogenesis via modulating CXCL12-CXCR4 axis signaling. Angiogenesis. 2025 May 2;28(3):25. doi: 10.1007/s10456-025-09977-5. PMID: 40314798; PMCID: PMC12048421. |
Loss of cep57 function induces G1 arrest and microcephaly
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Citation:
bioRxiv [preprint] 2025.04.10.648303; doi: https://doi.org/10.1101/2025.04.10.648303 Epub:
Not Epub Abstract:
Centrosomal protein 57 (CEP57) is essential for centrosome organization, regulating nucleation and stabilization of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Iyer S, Gokhale A, Shree Murugesan P, Kumar M. Loss of cep57 function induces G1 arrest and microcephaly. bioRxiv [preprint] 2025.04.10.648303; doi: https://doi.org/10.1101/2025.04.10.648303. |
A zebrafish model of intestinal epithelial damage reveals macrophages and igfbp1a as major modulators of mucosal healing
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Citation:
Mucosal Immunol. 2025 Apr 17:S1933-0219(25)00042-X. doi: 10.1016/j.mucimm.2025.04.004. Epub ahead of print. PMID: 40252728 Epub:
Not Epub Abstract:
Promoting intestinal regeneration and enhancing mucosal healing have emerged as promising therapeutic alternatives for treating... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Morales Castro RA, Kern BC, Díaz-Basabe A, Meinen ER, Zhao D, Zhou Y, Castillo F, Monasterio G, Farcas V, Chávez MN, Fransson J, Villablanca EJ. A zebrafish model of intestinal epithelial damage reveals macrophages and igfbp1a as major modulators of mucosal healing. Mucosal Immunol. 2025 Apr 17:S1933-0219(25)00042-X. doi: 10.1016/j.mucimm.2025.04.004. Epub ahead of print. PMID: 40252728. |
Alternative splicing of the Snap23 microexon is regulated by MBNL, QKI, and RBFOX2 in a tissue-specific manner and is mis-spliced in striated muscle diseases
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Citation:
RNA Biol. 2025 Apr 10. doi: 10.1080/15476286.2025.2491160. Epub ahead of print. PMID: 40207498 Epub:
Not Epub Abstract:
The reprogramming of alternative splicing networks during development is a hallmark of tissue maturation and identity.... Delivery Method:
electroporation Organism or Cell Type:
C2C12 myoblast cells Citation Extract: Gentile GM, Blue RE, Goda GA, Guzman BB, Szymanski RA, Lee EY, Engels NM, Hinkle ER, Wiedner HJ, Bishop AN, Harrison JT, Zhang H, Wehrens XHT, Dominguez D, Giudice J. Alternative splicing of the Snap23 microexon is regulated by MBNL, QKI, and RBFOX2 in a tissue-specific manner and is mis-spliced in striated muscle diseases. RNA Biol. 2025 Apr 10. doi: 10.1080/15476286.2025.2491160. Epub ahead of print. PMID: 40207498. |
Modulation of NMDA receptor signaling and zinc chelation prevent seizure-like events in a zebrafish model of SLC13A5 epilepsy
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Citation:
PLoS Biol. 2025 Apr 10;23(4):e3002499. doi: 10.1371/journal.pbio.3002499. Epub ahead of print. PMID: 40208862 Epub:
Not Epub Abstract:
SLC13A5 encodes a citrate transporter highly expressed in the brain and is important for regulating intra- and extracellular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dogra D, Phan VA, Zhang S, Gavrilovici C, DiMarzo N, Narang A, Ibhazehiebo K, Kurrasch DM. Modulation of NMDA receptor signaling and zinc chelation prevent seizure-like events in a zebrafish model of SLC13A5 epilepsy. PLoS Biol. 2025 Apr 10;23(4):e3002499. doi: 10.1371/journal.pbio.3002499. Epub ahead of print. PMID: 40208862. |
Pulmonary mitochondrial DNA release and activation of the cGAS-STING pathway in Lethal Stx12 knockout mice
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Citation:
Cell Commun Signal. 2025 Apr 8;23(1):174. doi: 10.1186/s12964-025-02141-y. PMID: 40200300; PMCID: PMC11980072 Epub:
Not Epub Abstract:
STX12 (syntaxin12 or syntaxin13), a member of the SNARE protein family, plays a crucial role in intracellular vesicle transport... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu DH, Li F, Yang RZ, Wu Z, Meng XY, Li SM, Li WX, Li JK, Wang DD, Wang RY, Li SA, Liu PP, Kang JS. Pulmonary mitochondrial DNA release and activation of the cGAS-STING pathway in Lethal Stx12 knockout mice. Cell Commun Signal. 2025 Apr 8;23(1):174. doi: 10.1186/s12964-025-02141-y. PMID: 40200300; PMCID: PMC11980072. |
Conception and synthesis of sequence-coded morpholinos
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Citation:
Chemistry. 2025 Apr 14:e202501161. doi: 10.1002/chem.202501161. Epub ahead of print. PMID: 40227092 Epub:
Not Epub Abstract:
Solid-phase morpholino chemistry was explored as a new route to synthesize abiological sequence-defined oligomers. Two... Delivery Method:
None Organism or Cell Type:
None Citation Extract: Pousse B, Al Ouahabi A, Baxter PNW, Charles L, Lutz JF. Conception and synthesis of sequence-coded morpholinos. Chemistry. 2025 Apr 14:e202501161. doi: 10.1002/chem.202501161. Epub ahead of print. PMID: 40227092. |