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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10704 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

The Atypical Kinase RIOK3 Limits RVFV Propagation and Is Regulated by Alternative Splicing

Authors:
Havranek KE, White LA, Bisom TC, Lanchy J-M, Lodmell JS
Citation:
Viruses. 2021;13(3):367. doi:10.3390/v13030367
Abstract:
In recent years, transcriptome profiling studies have identified changes in host splicing patterns caused by viral invasion,...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HEK293
Citation Extract:
Havranek KE, White LA, Bisom TC, Lanchy J-M, Lodmell JS. The Atypical Kinase RIOK3 Limits RVFV Propagation and Is Regulated by Alternative Splicing. Viruses. 2021;13(3):367. doi:10.3390/v13030367.

son is necessary for proper vertebrate blood development

Authors:
Belmonte RL, Engbretson IL, Kim JH, Cajias I, Ahn EE, Stachura DL
Citation:
PLoS One. 2021 Feb 25;16(2):e0247489. doi: 10.1371/journal.pone.0247489
Abstract:
The gene SON is on human chromosome 21 (21q22.11) and is thought to be associated with hematopoietic disorders that accompany...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Belmonte RL, Engbretson IL, Kim JH, Cajias I, Ahn EE, Stachura DL. son is necessary for proper vertebrate blood development. PLoS One. 2021 Feb 25;16(2):e0247489. doi: 10.1371/journal.pone.0247489.

Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease

Authors:
Lidberg KA, Annalora AJ, Jozic M, Elson DJ, Wang L, Bammler TK, Ramm S, Monteiro MB, Himmelfarb J, Marcus CB, Iversen PL, Kelly EJ
Citation:
Sci Rep. 2021;11(1):4722. doi:10.1038/s41598-021-84194-w
Abstract:
CYP3A5 is the primary CYP3A subfamily enzyme expressed in the human kidney and its aberrant expression may contribute to a...
Delivery Method:
cell bathing
Organism or Cell Type:
cell culture: HEK293, CV-1, primary human PTEC
Citation Extract:
Lidberg KA, Annalora AJ, Jozic M, Elson DJ, Wang L, Bammler TK, Ramm S, Monteiro MB, Himmelfarb J, Marcus CB, Iversen PL, Kelly EJ. Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease. Sci Rep. 2021;11(1):4722. doi:10.1038/s41598-021-84194-w.

Asymmetric Hapln1a drives regionalized cardiac ECM expansion and promotes heart morphogenesis in zebrafish development

Authors:
Derrick CJ, Sánchez-Posada J, Hussein F, Tessadori F, Pollitt EJG, Savage AM, Wilkinson RN, Chico TJ, van Eeden FJ, Bakkers J, Noël ES
Citation:
Cardiovasc Res. 2021;cvab004. doi:10.1093/cvr/cvab004
Abstract:
Aims: Vertebrate heart development requires the complex morphogenesis of a linear tube to form the mature organ, a process...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Derrick CJ, Sánchez-Posada J, Hussein F, Tessadori F, Pollitt EJG, Savage AM, Wilkinson RN, Chico TJ, van Eeden FJ, Bakkers J, Noël ES. Asymmetric Hapln1a drives regionalized cardiac ECM expansion and promotes heart morphogenesis in zebrafish development. Cardiovasc Res. 2021;cvab004. doi:10.1093/cvr/cvab004.

Quantitative intravital imaging in zebrafish reveals in vivo dynamics of physiological-stress-induced mitophagy

Authors:
Wrighton PJ, Shwartz A, Heo J-M, Quenzer ED, LaBella KA, Harper JW, Goessling W
Citation:
J Cell Sci. 2021;134:jcs256255 doi:10.1242/jcs.256255
Abstract:
Mitophagy, the selective recycling of mitochondria through autophagy, is a crucial metabolic process induced by cellular stress...
Organism or Cell Type:
zebrafish
Citation Extract:
Wrighton PJ, Shwartz A, Heo J-M, Quenzer ED, LaBella KA, Harper JW, Goessling W. Quantitative intravital imaging in zebrafish reveals in vivo dynamics of physiological-stress-induced mitophagy. J Cell Sci. 2021;134:jcs256255 doi:10.1242/jcs.256255.

EPHA2 Segregates with Microphthalmia and Congenital Cataracts in Two Unrelated Families

Authors:
Harding P, Toms M, Schiff E, Owen N, Bell S, Lloyd IC, Moosajee M
Citation:
Int J Mol Sci. 2021;22(4):2190. doi:10.3390/ijms22042190
Abstract:
EPHA2 is a transmembrane tyrosine kinase receptor that, when disrupted, causes congenital and age-related cataracts. Cat-Map...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Harding P, Toms M, Schiff E, Owen N, Bell S, Lloyd IC, Moosajee M. EPHA2 Segregates with Microphthalmia and Congenital Cataracts in Two Unrelated Families. Int J Mol Sci. 2021;22(4):2190. doi:10.3390/ijms22042190.

A 50 kdyne contusion spinal cord injury with or without the drug SS‐31 was not associated with major changes in muscle mass or gene expression 14 d after injury in young male mice

Authors:
Graham ZA, DeBerry JJ, Cardozo CP, Bamman MM
Citation:
Physiol Rep. 2021;9(4)e14751 doi:/10.14814/phy2.14751
Abstract:
Spinal cord injury (SCI) leads to rapid muscle atrophy due to paralysis/paresis and subsequent disuse. SS‐31 is a mitochondrial...
Organism or Cell Type:
cell culture: C2C12
Citation Extract:
Graham ZA, DeBerry JJ, Cardozo CP, Bamman MM. A 50 kdyne contusion spinal cord injury with or without the drug SS‐31 was not associated with major changes in muscle mass or gene expression 14 d after injury in young male mice. Physiol Rep. 2021;9(4)e14751 doi:/10.14814/phy2.14751.

Visualization of Transcriptional Activity in Early Zebrafish Primordial Germ Cells

Authors:
D'Orazio FM, Jasiulewicz A, Hadzhiev Y, Müller F
Citation:
Methods Mol Biol. 2021;2218:185-194. doi: 10.1007/978-1-0716-0970-5_15
Abstract:
Here, we describe a fast and straightforward methodology to in vivo detect transcriptional activity in the early zebrafish germ...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
D'Orazio FM, Jasiulewicz A, Hadzhiev Y, Müller F. Visualization of Transcriptional Activity in Early Zebrafish Primordial Germ Cells. Methods Mol Biol. 2021;2218:185-194. doi: 10.1007/978-1-0716-0970-5_15.

In Vitro Induction of Teleost PGCs

Authors:
Robles V, Valcarce DG, Riesco MF
Citation:
Methods Mol Biol. 2021;2218:75-83. doi:10.1007/978-1-0716-0970-5_7
Abstract:
Primordial germ cells (PGCs) are unique cells in an embryo. These cells contain all genetic information and therefore represent...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Robles V, Valcarce DG, Riesco MF. In Vitro Induction of Teleost PGCs. Methods Mol Biol. 2021;2218:75-83. doi:10.1007/978-1-0716-0970-5_7.

Masculinization of Zebrafish Through Partial Depletion of Primordial Germ Cells by Injecting Diluted Morpholino Oligonucleotides into Embryos

Authors:
Orbán L, Saju JM, Tzung KW, Liew WC
Citation:
Methods Mol Biol. 2021;2218:49-60. doi: 10.1007/978-1-0716-0970-5_5
Abstract:
The regulation of reproduction in zebrafish, the prime model of fish research, is not fully understood. An efficient tool to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Orbán L, Saju JM, Tzung KW, Liew WC. Masculinization of Zebrafish Through Partial Depletion of Primordial Germ Cells by Injecting Diluted Morpholino Oligonucleotides into Embryos. Methods Mol Biol. 2021;2218:49-60. doi: 10.1007/978-1-0716-0970-5_5.

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