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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10930 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

LAMP2A regulates the loading of proteins into exosomes

Authors:
Ferreira JV, da Rosa Soares A, Ramalho J, Carvalho CM, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.07.26.453637
Epub:
Not Epub
Abstract:
Exosomes are extracellular vesicles of endosomal origin released by virtually all cell types across metazoans. Exosomes are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ferreira JV, da Rosa Soares A, Ramalho J, Carvalho CM, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P. LAMP2A regulates the loading of proteins into exosomes. bioRxiv. 2021;[preprint] doi:10.1101/2021.07.26.453637 .

Extracellular mechanical forces drive endocardial cell volume decrease during cardiac valve morphogenesis

Authors:
Vermot J, Vignes H, Vagena-Pantoula C, Prakash M, Norden C, Jug F
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.07.27.453460
Epub:
Not Epub
Abstract:
Organ morphogenesis involves dynamic changes of tissue properties at the cellular scale. In addition, cells need to adapt to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vermot J, Vignes H, Vagena-Pantoula C, Prakash M, Norden C, Jug F. Extracellular mechanical forces drive endocardial cell volume decrease during cardiac valve morphogenesis. bioRxiv. 2021;[preprint] doi:10.1101/2021.07.27.453460 .

Paracrine regulation of neural crest EMT by placodal MMP28

Authors:
Gouignard N, Bibonne A, Mata JF, Bajanca F, Berki B, Barriga EH, Saint-Jeannet J-P, Theveneau E
Citation:
bioRxiv. 2020;[preprint]. doi:10.1101/2020.11.19.389544
Epub:
Not Epub
Abstract:
Epithelial-Mesenchymal Transition (EMT) is an early event in cell dissemination from epithelial tissues. EMT endows cells with...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gouignard N, Bibonne A, Mata JF, Bajanca F, Berki B, Barriga EH, Saint-Jeannet J-P, Theveneau E. Paracrine regulation of neural crest EMT by placodal MMP28. bioRxiv. 2020;[preprint]. doi:10.1101/2020.11.19.389544 .

Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target

Authors:
Raman R, Fallatah W, Al Qaryoute A, Dhinoja S, Jagadeeswaran P
Citation:
Sci Rep. 2021 Jul 27;11(1):15238. doi: 10.1038/s41598-021-94715-2
Epub:
Not Epub
Abstract:
Tissue factor pathway inhibitor (TFPI) is an anticoagulant protein that inhibits factor VIIa and Xa in the coagulation cascade...
Delivery Method:
Vivo-Morpholino piggyback hybrid
Organism or Cell Type:
zebrafish
Citation Extract:
Raman R, Fallatah W, Al Qaryoute A, Dhinoja S, Jagadeeswaran P. Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target. Sci Rep. 2021 Jul 27;11(1):15238. doi: 10.1038/s41598-021-94715-2.

Blood flow coordinates collective endothelial cell migration during vascular plexus formation and promotes angiogenic sprout regression via vegfr3/flt4

Authors:
Chen Y, Jiang Z, Fisher KH, Kim HR, Evans PC, Wilkinson RN
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.07.23.453496
Epub:
Not Epub
Abstract:
Nascent vascular networks adapt to the increasing metabolic demands of growing tissues by expanding via angiogenesis. As...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen Y, Jiang Z, Fisher KH, Kim HR, Evans PC, Wilkinson RN. Blood flow coordinates collective endothelial cell migration during vascular plexus formation and promotes angiogenic sprout regression via vegfr3/flt4. bioRxiv. 2021;[preprint] doi:10.1101/2021.07.23.453496 .

Systematic mapping of small nucleolar RNA targets in human cells

Authors:
Dunn-Davies H, Dudnakova T, Langhendries J-L, Watkins N, Lafontaine DLJ, Tollervey D
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.07.22.451324
Epub:
Not Epub
Abstract:
Altered expression of box C/D small nucleolar RNAs (snoRNAs) is implicated in human diseases, including cancer. Box C/D snoRNAs...
Organism or Cell Type:
cell culture: HEK
Citation Extract:
Dunn-Davies H, Dudnakova T, Langhendries J-L, Watkins N, Lafontaine DLJ, Tollervey D. Systematic mapping of small nucleolar RNA targets in human cells. bioRxiv. 2021;[preprint] doi:10.1101/2021.07.22.451324.

A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress

Authors:
Cacialli P, Mahony CB, Petzold T, Bordignon P, Rougemont A-L, Bertrand JY
Citation:
Nat Commun. 2021;12(1):4484. doi:10.1038/s41467-021-24831-0
Epub:
Not Epub
Abstract:
Reactive oxygen species (ROS) represent a by-product of metabolism and their excess is toxic for hematopoietic stem and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cacialli P, Mahony CB, Petzold T, Bordignon P, Rougemont A-L, Bertrand JY. A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress. Nat Commun. 2021;12(1):4484. doi:10.1038/s41467-021-24831-0.

An otopetrin family proton channel promotes cellular acid efflux critical for biomineralization in a marine calcifier

Authors:
Chang WW, Matt A-S, Schewe M, Musinszki M, Grüssel S, Brandenburg J, Garfield D, Bleich M, Baukrowitz T, Hu MY
Citation:
Proc Nat Acad Sci USA. 2021;118(30):e2101378118. doi:10.1073/pnas.2101378118
Epub:
Not Epub
Abstract:
Otopetrins comprise a family of proton-selective channels that are critically important for the mineralization of otoliths and...
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Chang WW, Matt A-S, Schewe M, Musinszki M, Grüssel S, Brandenburg J, Garfield D, Bleich M, Baukrowitz T, Hu MY. An otopetrin family proton channel promotes cellular acid efflux critical for biomineralization in a marine calcifier. Proc Nat Acad Sci USA. 2021;118(30):e2101378118. doi:10.1073/pnas.2101378118.

MARCH8 inhibits influenza A virus infection by targeting viral M2 protein for ubiquitination-dependent degradation in lysosomes

Authors:
Liu X, Xu F, Ren L, Zhao F, Huang Y, Wei L, Wang Y, Wang C, Fan Z, Mei S, Song J, Zhao Z, Cen S, Liang C, Wang J, Guo F
Citation:
Nat Commun. 2021;12:4427. doi:10.1038/s41467-021-24724-2
Epub:
Not Epub
Abstract:
The membrane-associated RING-CH (MARCH) proteins are E3 ligases that regulate the stability of various cellular membrane...
Delivery Method:
intranasal Vivo-Morpholino
Organism or Cell Type:
C57Bl/6 mice
Citation Extract:
Liu X, Xu F, Ren L, Zhao F, Huang Y, Wei L, Wang Y, Wang C, Fan Z, Mei S, Song J, Zhao Z, Cen S, Liang C, Wang J, Guo F. MARCH8 inhibits influenza A virus infection by targeting viral M2 protein for ubiquitination-dependent degradation in lysosomes. Nat Commun. 2021;12:4427. doi:10.1038/s41467-021-24724-2.

A novel nanoluciferase transgenic reporter to measure proteinuria in zebrafish

Authors:
Naylor RWW, Lemarie E, Jackson-Crawford A, Davenport JB, Mironov A, Lowe M, Lennon R
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.07.19.452884
Epub:
Not Epub
Abstract:
The zebrafish is an important animal system for modelling human diseases. This includes kidney dysfunction as the embryonic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Naylor RWW, Lemarie E, Jackson-Crawford A, Davenport JB, Mironov A, Lowe M, Lennon R. A novel nanoluciferase transgenic reporter to measure proteinuria in zebrafish. bioRxiv. 2021;[preprint] doi:10.1101/2021.07.19.452884.

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