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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10101 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

miR-129-5p: A key factor and therapeutic target in amyotrophic lateral sclerosis

Authors:
Loffreda A, Nizzardo M, Arosio A, Ruepp MD, Calogero RA, Volinia S, Galasso M, Bendotti C, Ferrarese C, Lunetta C, Rizzuti M, Ronchi A, Mühlemann O, Tremolizzo L, Corti S, Barabino SML
Citation:
Prog Neurobiol. 2020 Apr 23:101803. doi: 10.1016/j.pneurobio.2020.101803. [Epub ahead of print]
Abstract:
Amyotrophic lateral sclerosis (ALS) is a relentless and fatal neurological disease characterized by the selective degeneration...
Delivery Method:
intracerebroventricular (i.c.v.) injection
Organism or Cell Type:
mice
Citation Extract:
Loffreda A, Nizzardo M, Arosio A, Ruepp MD, Calogero RA, Volinia S, Galasso M, Bendotti C, Ferrarese C, Lunetta C, Rizzuti M, Ronchi A, Mühlemann O, Tremolizzo L, Corti S, Barabino SML. miR-129-5p: A key factor and therapeutic target in amyotrophic lateral sclerosis. Prog Neurobiol. 2020 Apr 23:101803. doi: 10.1016/j.pneurobio.2020.101803. [Epub ahead of print].

Rare mutations in the autophagy-regulating gene AMBRA1 contribute to human neural tube defects

Authors:
Ye J, Tong Y, Lv J, Peng R, Chen S, Kuang L, Su K, Zheng Y, Zhang T, Zhang F, Jin L, Yang X, Wang H
Citation:
Hum Mutat. 2020 Apr 25. doi: 10.1002/humu.24028. [Epub ahead of print]
Abstract:
Neural tube defects (NTDs) are severe congenital malformations caused by failed neural tube closure. Recently, autophagy is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ye J, Tong Y, Lv J, Peng R, Chen S, Kuang L, Su K, Zheng Y, Zhang T, Zhang F, Jin L, Yang X, Wang H. Rare mutations in the autophagy-regulating gene AMBRA1 contribute to human neural tube defects. Hum Mutat. 2020 Apr 25. doi: 10.1002/humu.24028. [Epub ahead of print].

A zebrafish model for HAX1-associated congenital neutropenia

Authors:
Doll L, Aghaallaei N, Dick AM, Welte K, Skokowa J, Bajoghli B
Citation:
Haematologica. 2020 Apr 23. pii: haematol.2019.240200. doi: 10.3324/haematol.2019.240200. [Epub ahead of print]
Abstract:
Severe congenital neutropenia (CN) is a rare heterogeneous group of diseases, characterized by a granulocytic maturation arrest...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Doll L, Aghaallaei N, Dick AM, Welte K, Skokowa J, Bajoghli B. A zebrafish model for HAX1-associated congenital neutropenia. Haematologica. 2020 Apr 23. pii: haematol.2019.240200. doi: 10.3324/haematol.2019.240200. [Epub ahead of print].

The SCF/KIT pathway implements self-organised epithelial patterning by cell movement

Authors:
Alexandre Chuyen, Charlotte Rulquin, Virginie Thome, Raphael Clement, Laurent Kodjabachian, Andrea Pasini
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.04.22.055483
Abstract:
How individual cell behaviours lead to the emergence of global patterns is poorly understood. In the Xenopus embryonic...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Alexandre Chuyen, Charlotte Rulquin, Virginie Thome, Raphael Clement, Laurent Kodjabachian, Andrea Pasini. The SCF/KIT pathway implements self-organised epithelial patterning by cell movement. bioRxiv. 2020;[preprint] doi:10.1101/2020.04.22.055483.

Dysregulation of NIPBL leads to impaired RUNX1 expression and haematopoietic defects

Authors:
Mazzola M, Pezzotta A, Fazio G, Rigamonti A, Bresciani E, Gaudenzi G, Pelleri MC, Saitta C, Ferrari L, Parma M, Fumagalli M, Biondi A, Cazzaniga G, Marozzi A, Pistocchi A
Citation:
J Cell Mol Med. 2020 Apr 23. doi: 10.1111/jcmm.15269. [Epub ahead of print]
Abstract:
The transcription factor RUNX1, a pivotal regulator of HSCs and haematopoiesis, is a frequent target of chromosomal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mazzola M, Pezzotta A, Fazio G, Rigamonti A, Bresciani E, Gaudenzi G, Pelleri MC, Saitta C, Ferrari L, Parma M, Fumagalli M, Biondi A, Cazzaniga G, Marozzi A, Pistocchi A. Dysregulation of NIPBL leads to impaired RUNX1 expression and haematopoietic defects. J Cell Mol Med. 2020 Apr 23. doi: 10.1111/jcmm.15269. [Epub ahead of print].

Vasohibin-1 mediated tubulin detyrosination selectively regulates secondary sprouting and lymphangiogenesis in the zebrafish trunk

Authors:
de Oliveira MB, Meier K, Coxam B, Geudens I, Jung S, Szymborska A, Gerhardt H
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.04.23.053256
Abstract:
Previous studies have shown that Vasohibin-1 (Vash-1) is stimulated by VEGFs in endothelial cells and that its overexpression...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
de Oliveira MB, Meier K, Coxam B, Geudens I, Jung S, Szymborska A, Gerhardt H. Vasohibin-1 mediated tubulin detyrosination selectively regulates secondary sprouting and lymphangiogenesis in the zebrafish trunk. bioRxiv. 2020;[preprint] doi:10.1101/2020.04.23.053256 .

Rac2 Regulates the Migration of T Lymphoid Progenitors to the Thymus during Zebrafish Embryogenesis

Authors:
Lu X, Zhang Y, Liu F, Wang L
Citation:
J Immunol. 2020;204(9):2447-54. doi:10.4049/jimmunol.1901494
Abstract:
The caudal hematopoietic tissue in zebrafish, the equivalent to the fetal liver in mammals, is an intermediate hematopoietic...
Organism or Cell Type:
zebrafish
Citation Extract:
Lu X, Zhang Y, Liu F, Wang L. Rac2 Regulates the Migration of T Lymphoid Progenitors to the Thymus during Zebrafish Embryogenesis. J Immunol. 2020;204(9):2447-54. doi:10.4049/jimmunol.1901494.

Role of the ADCY9 gene in cardiac abnormalities of the Rubinstein-Taybi syndrome

Authors:
Wu Y, Xia Y, Li P, Qu H-Q, Liu Y, Yang Y, Lin J, Zheng M, Tian L, Wu Z, Huang S, Qin X, Zhou X, Chen S, Liu Y, Wang Y, Li X, Zeng H, Hakonarson H, Zhuang J
Citation:
Orphanet J Rare Dis. 2020;15(1):101. doi:10.1186/s13023-020-01378-9
Abstract:
Background: Rubinstein–Taybi syndrome (RTS) is a rare, congenital, plurimalformative, and neurodevelopmental disorder. Previous...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu Y, Xia Y, Li P, Qu H-Q, Liu Y, Yang Y, Lin J, Zheng M, Tian L, Wu Z, Huang S, Qin X, Zhou X, Chen S, Liu Y, Wang Y, Li X, Zeng H, Hakonarson H, Zhuang J. Role of the ADCY9 gene in cardiac abnormalities of the Rubinstein-Taybi syndrome. Orphanet J Rare Dis. 2020;15(1):101. doi:10.1186/s13023-020-01378-9.

Zebrafish ambra1a and ambra1b Silencing Affect Heart Development

Authors:
Meneghetti G, Skobo T, Chrisam M, Fontana CM, Facchinello N, Nazio F, Cecconi F, Bonaldo P, Dalla Valle L
Citation:
Zebrafish. 2020 Apr 22. doi: 10.1089/zeb.2020.1860. [Epub ahead of print]
Abstract:
In zebrafish, two paralogous genes, activating molecule in beclin-1 (BECN1)-regulated autophagy ambra1a and ambra1b, both...
Citation Extract:
Meneghetti G, Skobo T, Chrisam M, Fontana CM, Facchinello N, Nazio F, Cecconi F, Bonaldo P, Dalla Valle L. Zebrafish ambra1a and ambra1b Silencing Affect Heart Development. Zebrafish. 2020 Apr 22. doi: 10.1089/zeb.2020.1860. [Epub ahead of print].

Twist3 is required for dedifferentiation during extraocular muscle regeneration in adult zebrafish

Authors:
Zhao Y, Louie KW, Tingle CF, Sha C, Heisel CJ, Unsworth SP, Kish PE, Kahana A
Citation:
PLoS ONE. 2020;15(4):e0231963. doi:10.1371/journal.pone.0231963
Abstract:
Severely damaged adult zebrafish extraocular muscles (EOMs) regenerate through dedifferentiation of residual myocytes involving...
Delivery Method:
injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao Y, Louie KW, Tingle CF, Sha C, Heisel CJ, Unsworth SP, Kish PE, Kahana A. Twist3 is required for dedifferentiation during extraocular muscle regeneration in adult zebrafish. PLoS ONE. 2020;15(4):e0231963. doi:10.1371/journal.pone.0231963.

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