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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11141 scientific papers returned from the database with the search filters currently being used below.

Zebrafish model for spondylo-megaepiphyseal-metaphyseal dysplasia reveals post-embryonic roles of Nkx3.2 in the skeleton

Authors:
Smeeton J, Natarajan N, Naveen Kumar A, Miyashita T, Baddam P, Fabian P, Graf D, Crump JG
Citation:
Development. 2021 Jan 25;148(2):dev193409. doi: 10.1242/dev.193409
Epub:
Not Epub
Abstract:
The regulated expansion of chondrocytes within growth plates and joints ensures proper skeletal development through adulthood....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Smeeton J, Natarajan N, Naveen Kumar A, Miyashita T, Baddam P, Fabian P, Graf D, Crump JG. Zebrafish model for spondylo-megaepiphyseal-metaphyseal dysplasia reveals post-embryonic roles of Nkx3.2 in the skeleton. Development. 2021 Jan 25;148(2):dev193409. doi: 10.1242/dev.193409.

Tbx15/18/22 shares a binding site with Tbx6-r.b to maintain expression of a muscle structural gene in ascidian late embryos

Authors:
Yu D, Iwamura Y, Satou Y, Oda-Ishii I
Citation:
Dev Biol. 2021;[Epub] doi:10.1016/j.ydbio.2021.12.012
Epub:
Not Epub
Abstract:
The ascidian larval tail contains muscle cells for swimming. Most of these muscle cells differentiate autonomously. The genetic...
Organism or Cell Type:
Ascidian
Citation Extract:
Yu D, Iwamura Y, Satou Y, Oda-Ishii I. Tbx15/18/22 shares a binding site with Tbx6-r.b to maintain expression of a muscle structural gene in ascidian late embryos. Dev Biol. 2021;[Epub] doi:10.1016/j.ydbio.2021.12.012.

Sensory axons induce epithelial lipid microdomain remodeling and determine the distribution of junctions in the epidermis

Authors:
Rosa JB, Nassman KY, Sagasti A
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.12.23.474011
Epub:
Not Epub
Abstract:
Epithelial cell properties are determined by the polarized distribution of membrane lipids, the cytoskeleton, and adhesive...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rosa JB, Nassman KY, Sagasti A. Sensory axons induce epithelial lipid microdomain remodeling and determine the distribution of junctions in the epidermis. bioRxiv. 2021;[preprint] doi:10.1101/2021.12.23.474011.

Bmp Signal Gradient Modulates Convergent Cell Movement via Xarhgef3.2 during Gastrulation of Xenopus Embryos

Authors:
Yoon J, Kumar V, Goutam RS, Kim S-C, Park S, Lee U, Kim J
Citation:
Cells. 2022;11(1):44. doi:10.3390/cells11010044
Epub:
Not Epub
Abstract:
Gastrulation is a critical step in the establishment of a basic body plan during development. Convergence and extension (CE)...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yoon J, Kumar V, Goutam RS, Kim S-C, Park S, Lee U, Kim J. Bmp Signal Gradient Modulates Convergent Cell Movement via Xarhgef3.2 during Gastrulation of Xenopus Embryos. Cells. 2022;11(1):44. doi:10.3390/cells11010044.

Coagulation Factor IIIa (f3a) Knockdown in Zebrafish Leads to Defective Angiogenesis and Mild Bleeding Phenotype

Authors:
Subramaniam S, Liu J, Fletcher C, Ramchandran R, Weiler H
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.12.21.473736
Epub:
Not Epub
Abstract:
Aim: Tissue factor (TF), an initiator of the extrinsic coagulation pathway, is crucial for embryogenesis, as mice lacking TF...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Subramaniam S, Liu J, Fletcher C, Ramchandran R, Weiler H. Coagulation Factor IIIa (f3a) Knockdown in Zebrafish Leads to Defective Angiogenesis and Mild Bleeding Phenotype. bioRxiv. 2021;[preprint] doi:10.1101/2021.12.21.473736.

Molecular mechanisms of embryonic tail development in the self-fertilizing mangrove killifish Kryptolebias marmoratus

Authors:
Saud HA, O'Neill PA, Ono Y, Verbruggen B, Van Aerle R, Kim J, Lee JS, Ring BC, Kudoh T
Citation:
Development. 2021 Dec 15;148(24):dev199675. doi: 10.1242/dev.199675. Epub 2021 Dec 24
Epub:
Not Epub
Abstract:
Using the self-fertilizing mangrove killifish, we characterized two mutants, shorttail (stl) and balltail (btl). These mutants...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Saud HA, O'Neill PA, Ono Y, Verbruggen B, Van Aerle R, Kim J, Lee JS, Ring BC, Kudoh T. Molecular mechanisms of embryonic tail development in the self-fertilizing mangrove killifish Kryptolebias marmoratus. Development. 2021 Dec 15;148(24):dev199675. doi: 10.1242/dev.199675. Epub 2021 Dec 24.

Methylmercury-induced hair cell loss requires hydrogen peroxide production and leukocytes in zebrafish embryos

Authors:
Luo Z, Guo S, Ho NY, Takamiya M, Strähle U, Yang L
Citation:
Toxicol Lett. 2021 Dec 23:S0378-4274(21)00918-8. doi: 10.1016/j.toxlet.2021.12.012. Online ahead of print
Epub:
Yes
Abstract:
Hearing impairment and deafness is frequently observed as one of the neurological signs in patients with Minamata disease...
Organism or Cell Type:
zebrafish
Citation Extract:
Luo Z, Guo S, Ho NY, Takamiya M, Strähle U, Yang L. Methylmercury-induced hair cell loss requires hydrogen peroxide production and leukocytes in zebrafish embryos. Toxicol Lett. 2021 Dec 23:S0378-4274(21)00918-8. doi: 10.1016/j.toxlet.2021.12.012. Online ahead of print.

Cyp11a2 is essential for oocyte development and spermatogonial stem cell differentiation in zebrafish

Authors:
Wang Y, Ye D, Zhang F, Zhang R, Zhu J, Wang H, He M, Sun Y
Citation:
Endocrinology. 2021;[epub] doi:10.1210/endocr/bqab258
Epub:
Yes
Abstract:
Cytochrome P45011A1, encoded by Cyp11a1, converts cholesterol to pregnenolone (P5), the first and rate-limiting step in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Y, Ye D, Zhang F, Zhang R, Zhu J, Wang H, He M, Sun Y. Cyp11a2 is essential for oocyte development and spermatogonial stem cell differentiation in zebrafish. Endocrinology. 2021;[epub] doi:10.1210/endocr/bqab258.

Methylome inheritance and enhancer dememorization reset an epigenetic gate safeguarding embryonic programs

Authors:
Wu X, Zhang H, Zhang B, Zhang Y, Wang Q, Shen W, Wu X, Li L, Xia W, Nakamura R, Liu B, Liu F, Takeda H, Meng A, Xie W
Citation:
Sci Adv. 2021;7(52):eabl3858 doi:10.1126/sciadv.abl3858
Epub:
Not Epub
Abstract:
Marked epigenetic reprogramming is essential to convert terminally differentiated gametes to totipotent embryos. It remains...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu X, Zhang H, Zhang B, Zhang Y, Wang Q, Shen W, Wu X, Li L, Xia W, Nakamura R, Liu B, Liu F, Takeda H, Meng A, Xie W. Methylome inheritance and enhancer dememorization reset an epigenetic gate safeguarding embryonic programs. Sci Adv. 2021;7(52):eabl3858 doi:10.1126/sciadv.abl3858.

Extracellular hyaluronate pressure shaped by cellular tethers drives tissue morphogenesis

Authors:
Munjal A, Hannezo A, Tsai TY-C, Mitchison TJ, Megason SG
Citation:
Cell. 2021;184(26):6313-25. doi:10.1016/j.cell.2021.11.025
Epub:
Not Epub
Abstract:
How tissues acquire complex shapes is a fundamental question in biology and regenerative medicine. Zebrafish semicircular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Munjal A, Hannezo A, Tsai TY-C, Mitchison TJ, Megason SG. Extracellular hyaluronate pressure shaped by cellular tethers drives tissue morphogenesis. Cell. 2021;184(26):6313-25. doi:10.1016/j.cell.2021.11.025.

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