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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9322 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand

Authors:
Pantazis CB, James MH, Bentzley BS, Aston-Jones G
Citation:
bioRxiv. 2019;[Preprint] doi:10.1101/547836
Abstract:
[no abstract included]
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Rats Sprague-Dawley male
Citation Extract:
Pantazis CB, James MH, Bentzley BS, Aston-Jones G. The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand. bioRxiv. 2019;[Preprint] doi:10.1101/547836.

A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation

Authors:
Hadzhiev Y, Qureshi HK, Wheatley L, Cooper L, Jasiulewicz A, Van Nguyen H, Wragg JW, Poovathumkadavil D, Conic S, Bajan S, Sik A, Hutvàgner G, Tora L, Gambus A, Fossey JS, Müller F
Citation:
Nat Commun. 2019 Feb 11;10(1):691. doi: 10.1038/s41467-019-08487-5
Abstract:
Most metazoan embryos commence development with rapid, transcriptionally silent cell divisions, with genome activation delayed...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hadzhiev Y, Qureshi HK, Wheatley L, Cooper L, Jasiulewicz A, Van Nguyen H, Wragg JW, Poovathumkadavil D, Conic S, Bajan S, Sik A, Hutvàgner G, Tora L, Gambus A, Fossey JS, Müller F. A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation. Nat Commun. 2019 Feb 11;10(1):691. doi: 10.1038/s41467-019-08487-5.

TBC1D8B Loss-of-Function Mutations Lead to X-Linked Nephrotic Syndrome via Defective Trafficking Pathways

Authors:
Dorval G, Kuzmuk V, Gribouval O, Welsh GI, Bierzynska A, Schmitt A, Miserey-Lenkei S, Koziell A, Haq S, Benmerah A, Mollet G, Boyer O, Saleem MA, Antignac C.
Citation:
Am J Hum Genet. 2019 Feb 7;104(2):348-355. doi: 10.1016/j.ajhg.2018.12.016. Epub 2019 Jan 17
Abstract:
Steroid-resistant nephrotic syndrome (SRNS) is characterized by high-range proteinuria and most often focal and segmental...
Organism or Cell Type:
zebrafish
Citation Extract:
Dorval G, Kuzmuk V, Gribouval O, Welsh GI, Bierzynska A, Schmitt A, Miserey-Lenkei S, Koziell A, Haq S, Benmerah A, Mollet G, Boyer O, Saleem MA, Antignac C.. TBC1D8B Loss-of-Function Mutations Lead to X-Linked Nephrotic Syndrome via Defective Trafficking Pathways. Am J Hum Genet. 2019 Feb 7;104(2):348-355. doi: 10.1016/j.ajhg.2018.12.016. Epub 2019 Jan 17.

Phage therapy against Pseudomonas aeruginosa infections in a cystic fibrosis zebrafish model

Authors:
Cafora M, Deflorian G, Forti F, Ferrari L, Binelli G, Briani F, Ghisotti D, Pistocchi A
Citation:
Sci Rep. 2019 Feb 6;9(1):1527. doi: 10.1038/s41598-018-37636-x
Abstract:
Cystic fibrosis (CF) is a hereditary disease due to mutations in the CFTR gene and causes mortality in humans mainly due to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cafora M, Deflorian G, Forti F, Ferrari L, Binelli G, Briani F, Ghisotti D, Pistocchi A. Phage therapy against Pseudomonas aeruginosa infections in a cystic fibrosis zebrafish model. Sci Rep. 2019 Feb 6;9(1):1527. doi: 10.1038/s41598-018-37636-x.

Dynamin binding protein is required for Xenopus laevis kidney development

Authors:
DeLay BD, Baldwin TA, Miller RK
Citation:
Front Physiol. 2019;[Epub ahead of print] doi:10.3389/fphys.2019.00143
Abstract:
The adult human kidney contains over one million nephrons, with each nephron consisting of a tube containing segments that have...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
DeLay BD, Baldwin TA, Miller RK. Dynamin binding protein is required for Xenopus laevis kidney development. Front Physiol. 2019;[Epub ahead of print] doi:10.3389/fphys.2019.00143.

Aneuploidy in Oocytes Is Prevented by Sustained CDK1 Activity through Degron Masking in CyclinB1

Authors:
Levasseur MD, Thomas C, Davies OR, Higgins JMG, Madgwick S
Citation:
Dev Cell. 2019;[Epub ahead of print] doi:10.1016/j.devcel.2019.01.008
Abstract:
Successful mitosis requires that cyclin B1:CDK1 ki-nase activity remains high until chromosomes arecorrectly aligned on the...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Levasseur MD, Thomas C, Davies OR, Higgins JMG, Madgwick S. Aneuploidy in Oocytes Is Prevented by Sustained CDK1 Activity through Degron Masking in CyclinB1. Dev Cell. 2019;[Epub ahead of print] doi:10.1016/j.devcel.2019.01.008.

Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish

Authors:
Huo X, Li H, Li Z, Yan C, Agrawal I, Mathavan S, Liu J, Gong Z
Citation:
Sci Rep. 2019 Feb 6;9(1):1509. doi: 10.1038/s41598-018-36605-8
Abstract:
We have previously demonstrated the pro-tumoral role of neutrophils using a kras-induced zebrafish hepatocarcinogenesis model....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huo X, Li H, Li Z, Yan C, Agrawal I, Mathavan S, Liu J, Gong Z. Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish. Sci Rep. 2019 Feb 6;9(1):1509. doi: 10.1038/s41598-018-36605-8.

Mutation of microphthalmia-associated transcription factor (mitf) in zebrafish sensitizes for glomerulopathy

Authors:
Müller-Deile J, Schenk H, Niggemann P, Bolaños-Palmieri P, Teng B, Higgs A, Staggs L, Haller H, Schroder P, Schiffer M
Citation:
Biol Open. 2019 Feb 4. pii: bio.040253. doi: 10.1242/bio.040253. [Epub ahead of print]
Abstract:
Different glomerular diseases that affect podocyte homeostasis can clinically present as nephrotic syndrome with massive...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Müller-Deile J, Schenk H, Niggemann P, Bolaños-Palmieri P, Teng B, Higgs A, Staggs L, Haller H, Schroder P, Schiffer M. Mutation of microphthalmia-associated transcription factor (mitf) in zebrafish sensitizes for glomerulopathy. Biol Open. 2019 Feb 4. pii: bio.040253. doi: 10.1242/bio.040253. [Epub ahead of print].

Production of Germ-Line Chimeras in Zebrafish

Authors:
Saito T, Goto R, Rivers N, Yamaha E
Citation:
Methods Mol Biol. 2019;1920:327-341. doi: 10.1007/978-1-4939-9009-2_20
Abstract:
The induction of germ-line chimerism in fish is a strategy for the reproduction of endangered or genetically valuable fish...
Organism or Cell Type:
zebrafish
Citation Extract:
Saito T, Goto R, Rivers N, Yamaha E. Production of Germ-Line Chimeras in Zebrafish. Methods Mol Biol. 2019;1920:327-341. doi: 10.1007/978-1-4939-9009-2_20.

Embryological and Genetic Manipulation of Chick Development

Authors:
Gammill LS, Jacques-Fricke B, Roffers-Agarwal J
Citation:
Methods Mol Biol. 2019;1920:75-97. doi: 10.1007/978-1-4939-9009-2_6
Abstract:
The ability to combine embryological manipulations with gene function analysis in an amniote embryo makes the chick a valuable...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Gammill LS, Jacques-Fricke B, Roffers-Agarwal J. Embryological and Genetic Manipulation of Chick Development. Methods Mol Biol. 2019;1920:75-97. doi: 10.1007/978-1-4939-9009-2_6.

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