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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9947 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Environmental relevant concentrations of benzophenone-3 induced developmental neurotoxicity in zebrafish

Authors:
Tao J, Bai C, Chen Y, Zhou H, Liu Y, Shi Q, Pan W, Dong H, Li L, Xu H, Tanguay R, Huang C, Dong Q
Citation:
Sci Total Envir. 2020;721:137686. doi:10.1016/j.scitotenv.2020.137686
Abstract:
Benzophenone-3 (BP3 or oxybenzone) is an organic UV filter that has been widely used in personal care products. Its frequent...
Organism or Cell Type:
zebrafish
Citation Extract:
Tao J, Bai C, Chen Y, Zhou H, Liu Y, Shi Q, Pan W, Dong H, Li L, Xu H, Tanguay R, Huang C, Dong Q. Environmental relevant concentrations of benzophenone-3 induced developmental neurotoxicity in zebrafish. Sci Total Envir. 2020;721:137686. doi:10.1016/j.scitotenv.2020.137686.

The dynein adaptor Hook2 plays essential roles in mitotic progression and cytokinesis

Authors:
Dwivedi D, Kumari A, Rathi S, Mylavarapu SVS, Sharma M
Citation:
J Cell Biol. 2019 Mar 4;218(3):871-894. doi: 10.1083/jcb.201804183. Epub 2019 Jan 23. Erratum in: J Cell Biol. 2019 Oct 7;218(10):3526-3527
Abstract:
Hook proteins are evolutionarily conserved dynein adaptors that promote assembly of highly processive dynein-dynactin motor...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dwivedi D, Kumari A, Rathi S, Mylavarapu SVS, Sharma M. The dynein adaptor Hook2 plays essential roles in mitotic progression and cytokinesis. J Cell Biol. 2019 Mar 4;218(3):871-894. doi: 10.1083/jcb.201804183. Epub 2019 Jan 23. Erratum in: J Cell Biol. 2019 Oct 7;218(10):3526-3527.

Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling

Authors:
Stratman AN, Farrelly OM, Mikelis CM, Miller MF, Wang Z,Pham VN, Davis AE, Burns MC, Pezoa SA, Castranova D, Yano JJ, Kilts TM, Davis GE, Gutkind JS, Weinstein BM
Citation:
Nat Comm. 2020;11(1):1204 doi:10.1038/s41467-020-14956-z
Abstract:
Anti-angiogenic therapies have generated significant interest for their potential to combat tumor growth. However, tumor...
Delivery Method:
microinjection, Vivo-Morpholino
Organism or Cell Type:
zebrafish, mice
Citation Extract:
Stratman AN, Farrelly OM, Mikelis CM, Miller MF, Wang Z,Pham VN, Davis AE, Burns MC, Pezoa SA, Castranova D, Yano JJ, Kilts TM, Davis GE, Gutkind JS, Weinstein BM. Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling. Nat Comm. 2020;11(1):1204 doi:10.1038/s41467-020-14956-z.

Biallelic variants in PSMB1 encoding the proteasome subunit β6 cause impairment of proteasome function, microcephaly, intellectual disability, developmental delay and short stature

Authors:
Ansar M, Ebstein F, Özkoç H, Paracha SA, Iwaszkiewicz J, Gesemann M, Zoete V, Ranza E, Santoni FA, Sarwar MT, Ahmed J, Krüger E, Bachmann-Gagescu R, Antonarakis SE
Citation:
Hum Molec Genet. 2020;[Epub] doi:10.1093/hmg/ddaa032
Abstract:
The molecular cause of the majority of rare autosomal recessive disorders remains unknown. Consanguinity due to extensive...
Organism or Cell Type:
zebrafish
Citation Extract:
Ansar M, Ebstein F, Özkoç H, Paracha SA, Iwaszkiewicz J, Gesemann M, Zoete V, Ranza E, Santoni FA, Sarwar MT, Ahmed J, Krüger E, Bachmann-Gagescu R, Antonarakis SE. Biallelic variants in PSMB1 encoding the proteasome subunit β6 cause impairment of proteasome function, microcephaly, intellectual disability, developmental delay and short stature. Hum Molec Genet. 2020;[Epub] doi:10.1093/hmg/ddaa032.

Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis

Authors:
Fujii K, Nakajo K, Egashira Y, Yamamoto Y, Kitada K, Taniguchi K, Kawai M, Tomiyama H, Kawakami K, Uchiyama K, Ono F
Citation:
Cell Rep. 2020;30(9):2879-88. doi:10.1016/j.celrep.2020.02.024
Abstract:
Peristalsis is indispensable for physiological function of the gut. The enteric nervous system (ENS) plays an important role in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fujii K, Nakajo K, Egashira Y, Yamamoto Y, Kitada K, Taniguchi K, Kawai M, Tomiyama H, Kawakami K, Uchiyama K, Ono F. Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis. Cell Rep. 2020;30(9):2879-88. doi:10.1016/j.celrep.2020.02.024.

H2 histamine receptor Vivo-Morpholino treatment ameliorates large bile duct damage in mice deficient in ATP binding cassette subfamily B member 4 (Abcb4-/-) via down-regulation of cAMP/ERK signaling

Authors:
Kennedy L, Meadows V, Kyritsi K, Pham L, Kundu D, Kulkarni R, Cerritos K, Demieville J, Hargrove L, Glaser S, Zhou T, Jaeger V, Alpini G, Francis H
Citation:
Am J Pathol. 2020;[Epub ahead of print] doi:10.1016/j.ajpath.2020.01.013
Abstract:
Histamine binds to one of the four G-protein–coupled receptors expressed by large cholangiocytes. Histamine specifically...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Kennedy L, Meadows V, Kyritsi K, Pham L, Kundu D, Kulkarni R, Cerritos K, Demieville J, Hargrove L, Glaser S, Zhou T, Jaeger V, Alpini G, Francis H. H2 histamine receptor Vivo-Morpholino treatment ameliorates large bile duct damage in mice deficient in ATP binding cassette subfamily B member 4 (Abcb4-/-) via down-regulation of cAMP/ERK signaling. Am J Pathol. 2020;[Epub ahead of print] doi:10.1016/j.ajpath.2020.01.013.

Genome-wide molecular effects of the neuropsychiatric 16p11 CNVs in an iPSC-to-iN neuronal model

Authors:
Ward TR, Zhang X, Louis C. Leung, Zhou B, Muench K, Roth JG, Khechaduri A, Plastini MJ, Charlton C, Pattni R, Ho S, Ho M, Huang Y, Hallmayer JF, Mourrain P, Palmer TD, Urban AE
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.09.940965
Abstract:
Copy number variants (CNVs), either deletions or duplications, at the 16p11.2 locus in the human genome are known to increase...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ward TR, Zhang X, Louis C. Leung, Zhou B, Muench K, Roth JG, Khechaduri A, Plastini MJ, Charlton C, Pattni R, Ho S, Ho M, Huang Y, Hallmayer JF, Mourrain P, Palmer TD, Urban AE. Genome-wide molecular effects of the neuropsychiatric 16p11 CNVs in an iPSC-to-iN neuronal model. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.09.940965 .

Transcriptome profiling of the branchial arches reveals cell type composition and a conserved signature of neural crest cell invasion

Authors:
Morrison JA, McLennan R, Teddy JM, Scott AR, Kasemeier-Kulesa K-K, Gogol MM, Kulesa PM
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.28.969915
Abstract:
The vertebrate branchial arches that give rise to structures of the head, neck, and heart form with very dynamic tissue growth...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Morrison JA, McLennan R, Teddy JM, Scott AR, Kasemeier-Kulesa K-K, Gogol MM, Kulesa PM. Transcriptome profiling of the branchial arches reveals cell type composition and a conserved signature of neural crest cell invasion. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.28.969915 .

Prmt5 promotes vascular morphogenesis in zebrafish independently of its methyltransferase activity

Authors:
Quillien A, Boulet M, Ethuin S, Vandel L
Citation:
BioRxiv. 2020;[preprint] doi:10.1101/2020.02.27.967810
Abstract:
In vertebrate, blood cell formation is tightly associated with the development of the vascular system. While the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Quillien A, Boulet M, Ethuin S, Vandel L. Prmt5 promotes vascular morphogenesis in zebrafish independently of its methyltransferase activity. BioRxiv. 2020;[preprint] doi:10.1101/2020.02.27.967810.

Zebrafish miR-462-731 is required for digestive organs development

Authors:
Huang Y, Huang C-X, Wang W-F, Liu H, Wang H-L
Citation:
Comp Biochem Physiol Part D Genomics Proteomics. 2020 Feb 29;34:100679. doi: 10.1016/j.cbd.2020.100679. [Epub ahead of print]
Abstract:
With-no-lysine (K)-1 (WNK1) is the founding member of family of four protein kinases with atypical placement of catalytic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huang Y, Huang C-X, Wang W-F, Liu H, Wang H-L. Zebrafish miR-462-731 is required for digestive organs development. Comp Biochem Physiol Part D Genomics Proteomics. 2020 Feb 29;34:100679. doi: 10.1016/j.cbd.2020.100679. [Epub ahead of print].

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