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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11585 scientific papers returned from the database with the search filters currently being used below.

Eteplirsen Use in a Boy with Duchenne Muscular Dystrophy and Sickle Cell Anemia

Authors:
Aiello GM, Cartwright MS
Citation:
Case Rep Neurol. 2022;14:404-7. doi:10.1159/000527358
Epub:
Not Epub
Abstract:
Eteplirsen is an antisense oligonucleotide used in the treatment of Duchenne muscular dys- trophy (DMD). The safety of...
Delivery Method:
i.v. infusion
Organism or Cell Type:
human
Citation Extract:
Aiello GM, Cartwright MS. Eteplirsen Use in a Boy with Duchenne Muscular Dystrophy and Sickle Cell Anemia. Case Rep Neurol. 2022;14:404-7. doi:10.1159/000527358.

Non-additive mixture effects of benzo[a]pyrene and pesticides in vitro and in vivo: Role of AhR signaling

Authors:
Endirlik B Ü, E Wincent, K Dreij
Citation:
Environ Pollut. 2022 Oct 25:120510. doi: 10.1016/j.envpol.2022.120510. Online ahead of print
Epub:
Yes
Abstract:
Polycyclic aromatic hydrocarbons (PAHs) and pesticides are two major groups of environmental contaminants which humans are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Endirlik B Ü, E Wincent, K Dreij. Non-additive mixture effects of benzo[a]pyrene and pesticides in vitro and in vivo: Role of AhR signaling. Environ Pollut. 2022 Oct 25:120510. doi: 10.1016/j.envpol.2022.120510. Online ahead of print.

The Potential Protective Effect and Underlying Mechanisms of Physiological Unconjugated Hyperbilirubinemia Mediated by UGT1A1 Antisense Oligonucleotide Therapy in a Mouse Model of Cyclosporine A-Induced Chronic Kidney Disease

Authors:
Marghani BH, El-Adl M, Ateya AI, Othman BH, Ghamry HI, Shukry M, Soliman MM, Rizk MA
Citation:
Metabolites. 2022 Oct 20;12(10):999. doi: 10.3390/metabo12100999
Epub:
Not Epub
Abstract:
Cyclosporine A (CSA) is an immunosuppressive drug that has improved transplant survival rates. However, its use is often...
Delivery Method:
i.v. injection
Organism or Cell Type:
mice
Citation Extract:
Marghani BH, El-Adl M, Ateya AI, Othman BH, Ghamry HI, Shukry M, Soliman MM, Rizk MA. The Potential Protective Effect and Underlying Mechanisms of Physiological Unconjugated Hyperbilirubinemia Mediated by UGT1A1 Antisense Oligonucleotide Therapy in a Mouse Model of Cyclosporine A-Induced Chronic Kidney Disease. Metabolites. 2022 Oct 20;12(10):999. doi: 10.3390/metabo12100999.

Morphogen gradient orchestrates pattern-preserving tissue morphogenesis via motility-driven unjamming

Authors:
Pinheiro D, Kardos R, Hannezo É, Heisenberg C-P
Citation:
Nat Phys. 2022;[Epub ahead of print] doi:10.1038/s41567-022-01787-6
Epub:
Yes
Abstract:
Embryo development requires biochemical signalling to generate patterns of cell fates and active mechanical forces to drive...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pinheiro D, Kardos R, Hannezo É, Heisenberg C-P. Morphogen gradient orchestrates pattern-preserving tissue morphogenesis via motility-driven unjamming. Nat Phys. 2022;[Epub ahead of print] doi:10.1038/s41567-022-01787-6.

Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis

Authors:
Afouda BA, Lynch AT, de Paiva Alves E, Hoppler S
Citation:
Data Brief. 2018 Jan 17;17:559-563. doi:10.1016/j.dib.2018.01.005. eCollection 2018 Apr
Epub:
Not Epub
Abstract:
The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiation. The data presented in...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Afouda BA, Lynch AT, de Paiva Alves E, Hoppler S. Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis. Data Brief. 2018 Jan 17;17:559-563. doi:10.1016/j.dib.2018.01.005. eCollection 2018 Apr.

Quantitative analysis of transcriptome dynamics provides novel insights into developmental state transitions

Authors:
Johnson K, Freedman S, Braun R, LaBonne C
Citation:
BMC Genomics. 2022;23:723. doi:10.1186/s12864-022-08953-3
Epub:
Not Epub
Abstract:
Background: During embryogenesis, the developmental potential of initially pluripotent cells becomes progressively restricted...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Johnson K, Freedman S, Braun R, LaBonne C. Quantitative analysis of transcriptome dynamics provides novel insights into developmental state transitions. BMC Genomics. 2022;23:723. doi:10.1186/s12864-022-08953-3.

Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation

Authors:
Chen X, Li Y, Xu J, Cui Y, Wu Q, Yin H, Li Y, Jiang L, Wang H, Wen Z, Yao Z, Wu Z
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.10.22.513336
Epub:
Not Epub
Abstract:
Styxl2, a poorly characterized pseudophosphatase, was identified as a transcriptional target of the Jak1-Stat1 pathway during...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen X, Li Y, Xu J, Cui Y, Wu Q, Yin H, Li Y, Jiang L, Wang H, Wen Z, Yao Z, Wu Z. Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation. bioRxiv. 2022;[preprint] doi:10.1101/2022.10.22.513336.

The Shape of the Jaw-Zebrafish Col11a1a Regulates Meckel's Cartilage Morphogenesis and Mineralization

Authors:
Reeck JC, Oxford JT
Citation:
J Dev Biol. 2022 Sep 22;10(4):40. doi: 10.3390/jdb10040040
Epub:
Not Epub
Abstract:
The expression of the col11a1a gene is essential for normal skeletal development, affecting both cartilage and bone. Loss of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Reeck JC, Oxford JT. The Shape of the Jaw-Zebrafish Col11a1a Regulates Meckel's Cartilage Morphogenesis and Mineralization. J Dev Biol. 2022 Sep 22;10(4):40. doi: 10.3390/jdb10040040.

Biallelic mutations of TTC12 and TTC21B were identified in Chinese patients with multisystem ciliopathy syndromes

Authors:
Chen W, Wang F, Zeng W, Zhang X, Shen L, Zhang Y, Zhou X
Citation:
Hum Genomics. 2022 Oct 22;16(1):48. doi: 10.1186/s40246-022-00421-z
Epub:
Not Epub
Abstract:
Background: Abnormalities in cilia ultrastructure and function lead to a range of human phenotypes termed ciliopathies. Many...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen W, Wang F, Zeng W, Zhang X, Shen L, Zhang Y, Zhou X. Biallelic mutations of TTC12 and TTC21B were identified in Chinese patients with multisystem ciliopathy syndromes. Hum Genomics. 2022 Oct 22;16(1):48. doi: 10.1186/s40246-022-00421-z.

Two distinct compartments of a ctenophore comb plate provide structural and functional integrity for the motility of giant multicilia

Authors:
Jokura K, Sato Y, Shiba K, Inaba K
Citation:
Curr Biol. 2022 Oct 19:S0960-9822(22)01603-7. doi:10.1016/j.cub.2022.09.061. Online ahead of print
Epub:
Yes
Abstract:
Comb plates are large ciliary structures uniquely seen in comb jellies (ctenophores).1-3 A comb plate is constructed from tens...
Citation Extract:
Jokura K, Sato Y, Shiba K, Inaba K. Two distinct compartments of a ctenophore comb plate provide structural and functional integrity for the motility of giant multicilia. Curr Biol. 2022 Oct 19:S0960-9822(22)01603-7. doi:10.1016/j.cub.2022.09.061. Online ahead of print.

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