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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Long-Term Dystrophin Replacement Therapy in Duchenne Muscular Dystrophy Causes Cardiac Inflammation
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Citation:
J Am Coll Cardiol Basic Trans Science. null2025, 0 (0). https://doi.org/10.1016/j.jacbts.2024.12.015 Epub:
Not Epub Abstract:
Micro-dystrophin replacement gene therapy is currently under clinical trials in Duchenne muscular dystrophy (DMD) patients.... Delivery Method:
peptide-linked combined therapy with AAV-U7; retro-orbital & intravenous (i.v.) Organism or Cell Type:
mice: C57BL/6J, dystrophin−/−; utrophin−/− dKO, mdx (utrophin−/−) Citation Extract: Forand A, Moog S, Mougenot N, Lemaitre M, Sevoz-Couche C, Guesmia Z, Virtanen L, Giordani L, Muchir A, Pietri-Rouxel F. Long-Term Dystrophin Replacement Therapy in Duchenne Muscular Dystrophy Causes Cardiac Inflammation. J Am Coll Cardiol Basic Trans Science. null2025, 0 (0). https://doi.org/10.1016/j.jacbts.2024.12.015. |
A nucleus-encoded dynamin-like protein controls endosymbiont division in the trypanosomatid Angomonas deanei
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Citation:
Sci Adv. 2025 Mar 21;11(12):eadp8518. doi: 10.1126/sciadv.adp8518. Epub 2025 Mar 19. PMID: 40106558 Epub:
Not Epub Abstract:
Angomonas deanei is a trypanosomatid of the Strigomonadinae. All members of this subfamily contain a single β-proteobacterial... Delivery Method:
electroporation Organism or Cell Type:
Angomonas deanei (trypanosoma) Citation Extract: Maurya AK, Kröninger L, Ehret G, Bäumers M, Marson M, Scheu S, Nowack ECM. A nucleus-encoded dynamin-like protein controls endosymbiont division in the trypanosomatid Angomonas deanei. Sci Adv. 2025 Mar 21;11(12):eadp8518. doi: 10.1126/sciadv.adp8518. Epub 2025 Mar 19. PMID: 40106558. |
Modeling epilepsy by loss-of-function of the CUG-binding protein Elav-like family member 2 in zebrafish with multi-omics analysis
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Citation:
Chin Med J (Engl). 2025 Mar 11. doi: 10.1097/CM9.0000000000003398. Epub ahead of print. PMID: 40066778 Epub:
Not Epub Abstract:
Background: The CUG-binding protein Elav-like family member 2 (CELF2) gene has been linked to the pathogenesis of epilepsy, but... Link:
Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang X, Zhang J, Rao X, Liu Y, Lin Z, Chen F, Luo R, Sun H, Gan J. Modeling epilepsy by loss-of-function of the CUG-binding protein Elav-like family member 2 in zebrafish with multi-omics analysis. Chin Med J (Engl). 2025 Mar 11. doi: 10.1097/CM9.0000000000003398. Epub ahead of print. PMID: 40066778. |
Zinc finger protein Znf296 is a cardiac-specific splicing regulator required for cardiomyocyte formation
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Citation:
Am J Pathol. 2025 Mar 21:S0002-9440(25)00078-1. doi: 10.1016/j.ajpath.2025.02.006. Epub ahead of print. PMID: 40122456 Epub:
Not Epub Abstract:
Heart formation and function are tightly regulated at transcriptional and post-transcriptional levels. The dysfunction of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li X, Yang S, Wang L, Zhang X, Zhang A, Wang Y, Shi DL, Li H. Zinc finger protein Znf296 is a cardiac-specific splicing regulator required for cardiomyocyte formation. Am J Pathol. 2025 Mar 21:S0002-9440(25)00078-1. doi: 10.1016/j.ajpath.2025.02.006. Epub ahead of print. PMID: 40122456. |
The Interaction Between the asb5a and asb5b Subtypes Jointly Regulates the L-R Asymmetrical Development of the Heart in Zebrafish
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Citation:
Int. J. Mol. Sci. 2025, 26, 2765. https://doi.org/10.3390/ijms26062765 Epub:
Not Epub Abstract:
The asb5 gene, a member of the Asb protein subfamily characterized by six ankyrin repeat domains, is highly conserved and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhou W, Cai W, Li Y, Gao L, Liu X, Liu S, Lei J, Zhang J, Wang Y, Jiang Z, Wu X, Fan X, Li F, Zheng L, Yuan W. The Interaction Between the asb5a and asb5b Subtypes Jointly Regulates the L-R Asymmetrical Development of the Heart in Zebrafish. Int. J. Mol. Sci. 2025, 26, 2765. https://doi.org/10.3390/ijms26062765. |
TRAP1 functions in the morphogenesis of the embryonic kidney
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Citation:
Anim Cells Syst (Seoul). 2025 Mar 12;29(1):9-18. doi: 10.1080/19768354.2025.2477789. PMID: 40098710; PMCID: PMC11912273 Epub:
Not Epub Abstract:
TNF receptor-associated protein1 (TRAP1) is a mitochondrial molecular chaperon with high homology with a cytosolic chaperon... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Kim HE, Kwon T, Sim HJ, Park TJ
. TRAP1 functions in the morphogenesis of the embryonic kidney. Anim Cells Syst (Seoul). 2025 Mar 12;29(1):9-18. doi: 10.1080/19768354.2025.2477789. PMID: 40098710; PMCID: PMC11912273. |
Elf1 Deficiency Impairs Macrophage Development in Zebrafish Model Organism
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Citation:
International Journal of Molecular Sciences. 2025; 26(6):2537. https://doi.org/10.3390/ijms26062537 Epub:
Not Epub Abstract:
The Ets (E-twenty-six) family of transcription factors plays a critical role in hematopoiesis and myeloid differentiation.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tan Q, Wang J, Hao Y, Yang S, Cao B, Pan W, Cao M. Elf1 Deficiency Impairs Macrophage Development in Zebrafish Model Organism . International Journal of Molecular Sciences. 2025; 26(6):2537. https://doi.org/10.3390/ijms26062537. |
TBK1 is involved in programmed cell death and ALS-related pathways in novel zebrafish models
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Citation:
Cell Death Discov. 2025 Mar 12;11(1):98. doi: 10.1038/s41420-025-02374-3. PMID: 40075110; PMCID: PMC11903655 Epub:
Not Epub Abstract:
Pathogenic mutations within the TBK1 gene leading to haploinsufficiency are causative of amyotrophic lateral sclerosis (ALS).... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Raas Q, Haouy G, de Calbiac H, Pasho E, Marian A, Guerrera IC, Rosello M, Oeckl P, Del Bene F, Catanese A, Ciura S, Kabashi E. TBK1 is involved in programmed cell death and ALS-related pathways in novel zebrafish models. Cell Death Discov. 2025 Mar 12;11(1):98. doi: 10.1038/s41420-025-02374-3. PMID: 40075110; PMCID: PMC11903655. |
PRMT5-mediated arginine methylation stabilizes GPX4 to suppress ferroptosis in cancer
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Citation:
Nat Cell Biol. 2025 Mar 3. doi: 10.1038/s41556-025-01610-3. Epub ahead of print. PMID: 40033101 Epub:
Not Epub Abstract:
The activation of ferroptosis has shown great potential for cancer therapy from an unconventional perspective, but revealing... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fan Y, Wang Y, Dan W, Zhang Y, Nie L, Ma Z, Zhuang Y, Liu B, Li M, Liu T, Wang Z, Ye L, Wei Y, Lei Y, Guo C, An J, Wang C, Zhang Y, Zeng J, Wei W, Gan B, Li L. PRMT5-mediated arginine methylation stabilizes GPX4 to suppress ferroptosis in cancer. Nat Cell Biol. 2025 Mar 3. doi: 10.1038/s41556-025-01610-3. Epub ahead of print. PMID: 40033101. |
Zebrafish (Danio rerio) TDP43 negatively regulates PKZ-IRF3–mediated IFN I response
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Citation:
The Journal of Immunology, 2025;, vkae035, https://doi.org/10.1093/jimmun/vkae035 Epub:
Not Epub Abstract:
Transactive response DNA binding protein 43 kD (TDP43), encoded by the tardbp gene, is a member of heterogenous nuclear... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yu T, Li M-M, Li M-F, Wang S, Feng Z, Zhang H, Liu J, Mao H, Li D, Hu C, Xu X. Zebrafish (Danio rerio) TDP43 negatively regulates PKZ-IRF3–mediated IFN I response. The Journal of Immunology, 2025;, vkae035, https://doi.org/10.1093/jimmun/vkae035. |