You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10468 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

N6-methyladenosine-modified CircRNA-SORE sustains sorafenib resistance in hepatocellular carcinoma by regulating β-catenin signaling

Authors:
Xu J, Wan Z, Tang M, Lin Z, Jiang S, Ji L, Gorshkov K, Mao Q, Xia S, Cen D, Zheng J, Liang X, Cai X
Citation:
Mol Cancer. 2020:19(1):163. doi:10.1186/s12943-020-01281-8
Abstract:
Background and aims: Accumulating evidence suggests that the primary and acquired resistance of hepatocellular carcinoma (HCC)...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HepG2-SR
Citation Extract:
Xu J, Wan Z, Tang M, Lin Z, Jiang S, Ji L, Gorshkov K, Mao Q, Xia S, Cen D, Zheng J, Liang X, Cai X. N6-methyladenosine-modified CircRNA-SORE sustains sorafenib resistance in hepatocellular carcinoma by regulating β-catenin signaling. Mol Cancer. 2020:19(1):163. doi:10.1186/s12943-020-01281-8.

Transcriptional regulation of EMT by nuclear MMP28

Authors:
Gouignard N, Bibonne A, Saint-Jeannet J-P, Theveneau E
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.19.389544
Abstract:
Epithelial-Mesenchymal Transition (EMT) is an early event in cell dissemination from epithelial tissues. EMT endows cells with...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gouignard N, Bibonne A, Saint-Jeannet J-P, Theveneau E. Transcriptional regulation of EMT by nuclear MMP28. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.19.389544 .

Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h

Authors:
Espanola SG, Song H, Ryu E, Saxena A, Kim E-S, Manegold JE, Nasamran CA, Sahoo D, Oh C-K, Bickers C, Shin U, Grainger S, Park YH, Pandolfo L, Kang M-S, Kang S, Myung K, Cooper KL, Yelon D, Traver D, Lee Y
Citation:
Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-00604-7
Abstract:
Haematopoietic stem and progenitor cells (HSPCs) have been the focus of developmental and regenerative studies, yet our...
Organism or Cell Type:
zebrafish
Citation Extract:
Espanola SG, Song H, Ryu E, Saxena A, Kim E-S, Manegold JE, Nasamran CA, Sahoo D, Oh C-K, Bickers C, Shin U, Grainger S, Park YH, Pandolfo L, Kang M-S, Kang S, Myung K, Cooper KL, Yelon D, Traver D, Lee Y. Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h. Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-00604-7.

STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells

Authors:
Jin L, Chen Y, Crossman DK, Datta A, Vu T, Mobley JA, Basu MK, Scarduzio M, Wang H, Chang C, Datta PK
Citation:
Nat Comm. 2020;11(1):5941. doi:10.1038/s41467-020-19698-6
Abstract:
Alternative splicing (AS) is involved in cell fate decisions and embryonic development. However, regulation of these processes...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Jin L, Chen Y, Crossman DK, Datta A, Vu T, Mobley JA, Basu MK, Scarduzio M, Wang H, Chang C, Datta PK. STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells. Nat Comm. 2020;11(1):5941. doi:10.1038/s41467-020-19698-6.

PDE10A inhibition reduces the manifestation of pathology in DMD zebrafish and represses the genetic modifier PITPNA

Authors:
Lambert MR, Spinazzola JM, Widrick JJ, Pakula A, Conner JR, Chin JE, Owens JM, Kunkel LM
Citation:
Mol Ther. 2020;[Epub ahead of print] doi:10.1016/j.ymthe.2020.11.021
Abstract:
Duchenne Muscular Dystrophy (DMD) is a severe genetic disorder caused by mutations in the DMD gene. Absence of dystrophin...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lambert MR, Spinazzola JM, Widrick JJ, Pakula A, Conner JR, Chin JE, Owens JM, Kunkel LM. PDE10A inhibition reduces the manifestation of pathology in DMD zebrafish and represses the genetic modifier PITPNA. Mol Ther. 2020;[Epub ahead of print] doi:10.1016/j.ymthe.2020.11.021.

The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network

Authors:
Grocott T, Lozano-Velasco E, Mok GF, Münsterberg AE
Citation:
Development. 2020;[Epub ahead of print] doi:10.1242/dev.185827
Abstract:
\Understanding how complex organ systems are assembled from simple embryonic tissues is a major challenge. Across the animal...
Delivery Method:
Endo-Porter PEG
Organism or Cell Type:
cell culture: Gallus gallus (chick) somite tissue
Citation Extract:
Grocott T, Lozano-Velasco E, Mok GF, Münsterberg AE. The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network. Development. 2020;[Epub ahead of print] doi:10.1242/dev.185827.

Hes5.9 Coordinate FGF and Notch Signaling to Modulate Gastrulation via Regulating Cell Fate Specification and Cell Migration in Xenopus tropicalis

Authors:
Huang X, Zhang L, Yang S, Zhang Y, Wu M, Chen P
Citation:
Genes. 2020:11(11):2073-4425. doi:10.3390/genes11111363
Abstract:
Gastrulation drives the establishment of three germ layers and embryonic axes during frog embryonic development. Mesodermal...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Huang X, Zhang L, Yang S, Zhang Y, Wu M, Chen P. Hes5.9 Coordinate FGF and Notch Signaling to Modulate Gastrulation via Regulating Cell Fate Specification and Cell Migration in Xenopus tropicalis. Genes. 2020:11(11):2073-4425. doi:10.3390/genes11111363.

Cell-to-cell heterogeneity in Sox2 and Brachyury expression guides progenitor destiny by controlling their movements

Authors:
Romanos M, Allio G, Combres L, Medevielle F, Escalas N, Soula C, Steventon B, Trescases A, Benazeraf B
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.18.388611
Abstract:
Although cell-to-cell heterogeneity in gene and protein expression has been widely documented within a given cell population,...
Delivery Method:
electroporation
Organism or Cell Type:
Coturnix japonica (quail)
Citation Extract:
Romanos M, Allio G, Combres L, Medevielle F, Escalas N, Soula C, Steventon B, Trescases A, Benazeraf B. Cell-to-cell heterogeneity in Sox2 and Brachyury expression guides progenitor destiny by controlling their movements. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.18.388611 .

Antagonistic activities of Fmn2 and ADF regulate axonal F-actin patch dynamics and the initiation of collateral branching

Authors:
Kundu T, Das SS, Kumar DS, Sewatkar LK, Ghose A
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.16.384099
Abstract:
Interstitial collateral branching of axons is a critical component in the development of functional neural circuits. Axon...
Organism or Cell Type:
cell culture: chick spinal neurons
Citation Extract:
Kundu T, Das SS, Kumar DS, Sewatkar LK, Ghose A. Antagonistic activities of Fmn2 and ADF regulate axonal F-actin patch dynamics and the initiation of collateral branching. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.16.384099.

PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia

Authors:
Monroe TO, Garrett ME, Kousi M, Rodriguiz RM, Moon S, Bai Y, Brodar SC, Soldano KL, Savage J, Hansen TF, Muzny DM, Gibbs RA, Barak L, Sullivan PF, Ashley-Koch AE, Sawa A, Wetsel WC, Werge T, Katsanis N
Citation:
Nat Comm. 2020;11:5903. doi:10.1038/s41467-020-19637-5
Abstract:
The neuronal primary cilium and centriolar satellites have functions in neurogenesis, but little is known about their roles in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Monroe TO, Garrett ME, Kousi M, Rodriguiz RM, Moon S, Bai Y, Brodar SC, Soldano KL, Savage J, Hansen TF, Muzny DM, Gibbs RA, Barak L, Sullivan PF, Ashley-Koch AE, Sawa A, Wetsel WC, Werge T, Katsanis N. PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia. Nat Comm. 2020;11:5903. doi:10.1038/s41467-020-19637-5.

Pages