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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10930 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Tril dampens Nodal signaling through Pellino2- and Traf6-mediated activation of Nedd4l

Authors:
Kim H-S, Green YS, Xie Y, Christian JL
Citation:
Proc Nat Acad Sci USA. 2021:118(36)e2104661118. doi:10.1073/pnas.2104661118
Epub:
Yes
Abstract:
Toll-like receptor 4 (Tlr) interactor with leucine-rich repeats (Tril) functions as a Tlr coreceptor to mediate innate immunity...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kim H-S, Green YS, Xie Y, Christian JL. Tril dampens Nodal signaling through Pellino2- and Traf6-mediated activation of Nedd4l. Proc Nat Acad Sci USA. 2021:118(36)e2104661118. doi:10.1073/pnas.2104661118.

Developmental Angiogenesis Requires the Mitochondrial Phenylalanyl-tRNA Synthetase

Authors:
Li B, Chen K, Liu F, Zhang J, Chen X, Chen T, Chen Q, Yao Y, Hu W, Wang L, Wu Y
Citation:
Front Cardiovasc Med. 2021;8:1000. doi:10.3389/fcvm.2021.724846
Epub:
Not Epub
Abstract:
Background: Mitochondrial aminoacyl-tRNA synthetases (mtARSs) catalyze the binding of specific amino acids to their cognate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li B, Chen K, Liu F, Zhang J, Chen X, Chen T, Chen Q, Yao Y, Hu W, Wang L, Wu Y. Developmental Angiogenesis Requires the Mitochondrial Phenylalanyl-tRNA Synthetase. Front Cardiovasc Med. 2021;8:1000. doi:10.3389/fcvm.2021.724846.

Efficient Generation of Knock-In Zebrafish Models for Inherited Disorders Using CRISPR-Cas9 Ribonucleoprotein Complexes

Authors:
de Vrieze E, de Bruijn SE, Reurink J, Broekman S, van de Riet V, Aben M, Kremer H, van Wijk E
Citation:
Int J Mol Sci. 2021; 22(17):9429. doi:10.3390/ijms22179429
Epub:
Not Epub
Abstract:
CRISPR-Cas9-based genome-editing is a highly efficient and cost-effective method to generate zebrafish loss-of-function alleles...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
de Vrieze E, de Bruijn SE, Reurink J, Broekman S, van de Riet V, Aben M, Kremer H, van Wijk E. Efficient Generation of Knock-In Zebrafish Models for Inherited Disorders Using CRISPR-Cas9 Ribonucleoprotein Complexes. Int J Mol Sci. 2021; 22(17):9429. doi:10.3390/ijms22179429.

The CCAAT/Enhancer Binding Protein Beta (cebpb) is essential for the development of enveloping layer (EVL) in zebrafish

Authors:
Zhang X, Wu Z, Bu M, Hu R, Zhang X, Li W, Chen L
Citation:
Aquac Fish. 2021;[Epub] doi:10.1016/j.aaf.2021.07.003
Epub:
Yes
Abstract:
Epiboly, the coordinated spreading of the enveloping layer (EVL), the yolk syncytial layer (YSL) and the deep cells (DCs)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang X, Wu Z, Bu M, Hu R, Zhang X, Li W, Chen L. The CCAAT/Enhancer Binding Protein Beta (cebpb) is essential for the development of enveloping layer (EVL) in zebrafish. Aquac Fish. 2021;[Epub] doi:10.1016/j.aaf.2021.07.003.

Ptk7 Is Dynamically Localized at Neural Crest Cell-Cell Contact Sites and Functions in Contact Inhibition of Locomotion

Authors:
Grund A, Till K, Giehl K, Borchers A
Citation:
Int J Mol Sci. 2021;22(17):9324. doi:10.3390/ijms22179324
Epub:
Not Epub
Abstract:
Neural crest (NC) cells are highly migratory cells that contribute to various vertebrate tissues, and whose migratory behaviors...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Grund A, Till K, Giehl K, Borchers A. Ptk7 Is Dynamically Localized at Neural Crest Cell-Cell Contact Sites and Functions in Contact Inhibition of Locomotion. Int J Mol Sci. 2021;22(17):9324. doi:10.3390/ijms22179324.

Loss of Ift74 Leads to Slow Photoreceptor Degeneration and Ciliogenesis Defects in Zebrafish

Authors:
Zhu P, Xu J, Wang Y, Zhao C
Citation:
Int J Mol Sci. 2021;22(17):9329. doi:10.3390/ijms22179329
Epub:
Not Epub
Abstract:
Cilia are microtubule-based structures projecting from the cell surface that perform diverse biological functions. Ciliary...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhu P, Xu J, Wang Y, Zhao C. Loss of Ift74 Leads to Slow Photoreceptor Degeneration and Ciliogenesis Defects in Zebrafish. Int J Mol Sci. 2021;22(17):9329. doi:10.3390/ijms22179329.

NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis

Authors:
Liu M, Zhang W, Li M, Feng J, Kuang W, Chen X, Yang F, Sun Q, Xu Z, Hua J, Yang C, Liu W, Shu Q, Yang Y, Zhou T, Xie S
Citation:
Cell Res. 2021 Sep 3. doi: 10.1038/s41422-021-00560-3. Online ahead of print
Epub:
Yes
Abstract:
Primary cilia extending from mother centrioles are essential for vertebrate development and homeostasis maintenance. Centriolar...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu M, Zhang W, Li M, Feng J, Kuang W, Chen X, Yang F, Sun Q, Xu Z, Hua J, Yang C, Liu W, Shu Q, Yang Y, Zhou T, Xie S. NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis. Cell Res. 2021 Sep 3. doi: 10.1038/s41422-021-00560-3. Online ahead of print.

A novel mouse model of PMS2 founder mutation that causes mismatch repair defect due to aberrant splicing

Authors:
Biswas K, Couillard M, Cavallone L, Burkett S, Stauffer S, Martin BK, Southon E, Reid S, Plona TM, Baugher RN, Mellott SD, Pike KM, Albaugh ME, Maedler-Kron C, Hamel N, Tessarollo L, Marcus V, Foulkes WD, Sharan SK
Citation:
Cell Death Dis. 2021 Sep 6;12(9):838. doi: 10.1038/s41419-021-04130-8
Epub:
Not Epub
Abstract:
Hereditary non-polyposis colorectal cancer, now known as Lynch syndrome (LS) is one of the most common cancer predisposition...
Delivery Method:
electroporation, Vivo-Morpholino
Organism or Cell Type:
cell culture: human and murine fibroblasts, mice
Citation Extract:
Biswas K, Couillard M, Cavallone L, Burkett S, Stauffer S, Martin BK, Southon E, Reid S, Plona TM, Baugher RN, Mellott SD, Pike KM, Albaugh ME, Maedler-Kron C, Hamel N, Tessarollo L, Marcus V, Foulkes WD, Sharan SK. A novel mouse model of PMS2 founder mutation that causes mismatch repair defect due to aberrant splicing. Cell Death Dis. 2021 Sep 6;12(9):838. doi: 10.1038/s41419-021-04130-8.

Function of chromatin modifier Hmgn1 during neural crest and craniofacial development

Authors:
Ihewulezi C, Saint-Jeannet JP
Citation:
Genesis. 2021 Sep 3:e23447. doi: 10.1002/dvg.23447. Online ahead of print
Epub:
Yes
Abstract:
The neural crest is a dynamic embryonic structure that plays a major role in the formation of the vertebrate craniofacial...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ihewulezi C, Saint-Jeannet JP. Function of chromatin modifier Hmgn1 during neural crest and craniofacial development. Genesis. 2021 Sep 3:e23447. doi: 10.1002/dvg.23447. Online ahead of print.

Adar-mediated A-to-I editing is required for establishment of embryonic body axes in zebrafish

Authors:
Niescierowicz K, Pryszcz L, Navarrete C, Tralle E, Kasprzyk ME, Nahia KA, Misztal K, Bochtler M, Winata C
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.08.26.457081
Epub:
Not Epub
Abstract:
Adenosine deaminases (ADARs) catalyze the deamination of adenosine to inosine, also known as A-to-I editing, in RNA. Although A...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Niescierowicz K, Pryszcz L, Navarrete C, Tralle E, Kasprzyk ME, Nahia KA, Misztal K, Bochtler M, Winata C. Adar-mediated A-to-I editing is required for establishment of embryonic body axes in zebrafish. bioRxiv. 2021;[preprint] doi:10.1101/2021.08.26.457081.

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