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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11141 scientific papers returned from the database with the search filters currently being used below.

A Gene Implicated in Activation of Retinoic Acid Receptor Targets Is a Novel Renal Agenesis Gene in Humans

Authors:
Brophy PD, Rasmussen M, Parida M, Bonde G, Darbro BW, Hong X, Clarke JC, Peterson KA, Denegre J, Schneider M, Sussman CR, Sunde L, Lildballe DL, Hertz JM, Cornell RA, Murray SA, Manak JR
Citation:
Genetics. 2017 Sep;207(1):215-228. doi: 10.1534/genetics.117.1125. Epub 2017 Jul 24
Epub:
Not Epub
Abstract:
Renal agenesis (RA) is one of the more extreme examples of congenital anomalies of the kidney and urinary tract (CAKUT)....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brophy PD, Rasmussen M, Parida M, Bonde G, Darbro BW, Hong X, Clarke JC, Peterson KA, Denegre J, Schneider M, Sussman CR, Sunde L, Lildballe DL, Hertz JM, Cornell RA, Murray SA, Manak JR. A Gene Implicated in Activation of Retinoic Acid Receptor Targets Is a Novel Renal Agenesis Gene in Humans. Genetics. 2017 Sep;207(1):215-228. doi: 10.1534/genetics.117.1125. Epub 2017 Jul 24.

The Thyroid Hormone Inactivating Type 3 Deiodinase Is Essential for Optimal Neutrophil Function: Observations From Three Species

Authors:
van der Spek AH, Jim KK, Karaczyn A, van Beeren HC, Ackermans MT, Darras VM, Vandenbroucke-Grauls CMJE, Hernandez A, Brouwer MC, Fliers E, van de Beek D, Boelen A
Citation:
Endocrinology. 2018 Feb 1;159(2):826-835. doi: 10.1210/en.2017-00666
Epub:
Not Epub
Abstract:
Neutrophils are essential effector cells of the innate immune system that have recently been recognized as thyroid hormone (TH...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
van der Spek AH, Jim KK, Karaczyn A, van Beeren HC, Ackermans MT, Darras VM, Vandenbroucke-Grauls CMJE, Hernandez A, Brouwer MC, Fliers E, van de Beek D, Boelen A. The Thyroid Hormone Inactivating Type 3 Deiodinase Is Essential for Optimal Neutrophil Function: Observations From Three Species. Endocrinology. 2018 Feb 1;159(2):826-835. doi: 10.1210/en.2017-00666.

Roles of Xenopus chemokine ligand CXCLh (XCXCLh) in early embryogenesis

Authors:
Goto T, Ito Y, Michiue T
Citation:
Dev Growth Differ. 2018 May;60(4):226-238. doi: 10.1111/dgd.12432. Epub 2018 Apr 26
Epub:
Not Epub
Abstract:
Several chemokine molecules control cell movements during early morphogenesis. However, it is unclear whether chemokine...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Goto T, Ito Y, Michiue T. Roles of Xenopus chemokine ligand CXCLh (XCXCLh) in early embryogenesis. Dev Growth Differ. 2018 May;60(4):226-238. doi: 10.1111/dgd.12432. Epub 2018 Apr 26.

Nppa and Nppb act redundantly during zebrafish cardiac development to confine AVC marker expression and reduce cardiac jelly volume

Authors:
Grassini DR, Lagendijk AK, De Angelis JE, Da Silva J, Jeanes A, Zettler N, Bower NI, Hogan BM, Smith KA
Citation:
Development. 2018 Jun 15;145(12):dev160739. doi: 10.1242/dev.160739
Epub:
Not Epub
Abstract:
Atrial natriuretic peptide (nppa/anf) and brain natriuretic peptide (nppb/bnp) form a gene cluster with expression in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Grassini DR, Lagendijk AK, De Angelis JE, Da Silva J, Jeanes A, Zettler N, Bower NI, Hogan BM, Smith KA. Nppa and Nppb act redundantly during zebrafish cardiac development to confine AVC marker expression and reduce cardiac jelly volume. Development. 2018 Jun 15;145(12):dev160739. doi: 10.1242/dev.160739.

Overexpression of Human Mutant PANK2 Proteins Affects Development and Motor Behavior of Zebrafish Embryos

Authors:
Khatri D, Zizioli D, Trivedi A, Borsani G, Monti E, Finazzi D
Citation:
Neuromolecular Med. 2019 Jun;21(2):120-131. doi: 10.1007/s12017-018-8508-8. Epub 2018 Aug 23
Epub:
Not Epub
Abstract:
Pantothenate Kinase-Associated Neurodegeneration (PKAN) is a genetic and early-onset neurodegenerative disorder characterized...
Organism or Cell Type:
zebrafish
Citation Extract:
Khatri D, Zizioli D, Trivedi A, Borsani G, Monti E, Finazzi D. Overexpression of Human Mutant PANK2 Proteins Affects Development and Motor Behavior of Zebrafish Embryos. Neuromolecular Med. 2019 Jun;21(2):120-131. doi: 10.1007/s12017-018-8508-8. Epub 2018 Aug 23.

Neural crest development in Xenopus requires Protocadherin 7 at the lateral neural crest border

Authors:
Bradley RS
Citation:
Mech Dev. 2018 Feb;149:41-52. doi: 10.1016/j.mod.2018.01.002. Epub 2018 Jan 31
Epub:
Not Epub
Abstract:
In vertebrates, the neural crest is a unique population of pluripotent cells whose development is dependent on signaling from...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Bradley RS. Neural crest development in Xenopus requires Protocadherin 7 at the lateral neural crest border. Mech Dev. 2018 Feb;149:41-52. doi: 10.1016/j.mod.2018.01.002. Epub 2018 Jan 31.

sox2 and sox3 cooperate to regulate otic/epibranchial placode induction in zebrafish

Authors:
Gou Y, Guo J, Maulding K, Riley BB
Citation:
Dev Biol. 2018 Mar 1;435(1):84-95. doi: 10.1016/j.ydbio.2018.01.011. Epub 2018 Feb 13
Epub:
Not Epub
Abstract:
Expression of sox3 is one of the earliest markers of Fgf-dependent otic/epibranchial placode induction. We report here that...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gou Y, Guo J, Maulding K, Riley BB. sox2 and sox3 cooperate to regulate otic/epibranchial placode induction in zebrafish. Dev Biol. 2018 Mar 1;435(1):84-95. doi: 10.1016/j.ydbio.2018.01.011. Epub 2018 Feb 13.

Catch-Up Growth in Zebrafish Embryo Requires Neural Crest Cells Sustained by Irs1 Signaling

Authors:
Kamei H, Yoneyama Y, Hakuno F, Sawada R, Shimizu T, Duan C, Takahashi SI
Citation:
Endocrinology. 2018 Apr 1;159(4):1547-1560. doi: 10.1210/en.2017-00847
Epub:
Not Epub
Abstract:
Most animals display retarded growth in adverse conditions; however, upon the removal of unfavorable factors, they often show...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kamei H, Yoneyama Y, Hakuno F, Sawada R, Shimizu T, Duan C, Takahashi SI. Catch-Up Growth in Zebrafish Embryo Requires Neural Crest Cells Sustained by Irs1 Signaling. Endocrinology. 2018 Apr 1;159(4):1547-1560. doi: 10.1210/en.2017-00847.

Knockdown of chondroitin-4-sulfotransferase-1, but not of dermatan-4-sulfotransferase-1, accelerates regeneration of zebrafish after spinal cord injury

Authors:
Sahu S, Li R, Loers G, Schachner M
Citation:
FASEB J. 2019 Feb;33(2):2252-2262. doi: 10.1096/fj.201800852RR. Epub 2018 Oct 19
Epub:
Not Epub
Abstract:
Glycosaminoglycans such as chondroitin sulfate (CS) and dermatan sulfate (DS) are long chains of repeating disaccharide units,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sahu S, Li R, Loers G, Schachner M. Knockdown of chondroitin-4-sulfotransferase-1, but not of dermatan-4-sulfotransferase-1, accelerates regeneration of zebrafish after spinal cord injury. FASEB J. 2019 Feb;33(2):2252-2262. doi: 10.1096/fj.201800852RR. Epub 2018 Oct 19.

pouC Regulates Expression of bmp4 During Atrioventricular Canal Formation in Zebrafish

Authors:
Bhakta M, Padanad MS, Harris JP, Lubczyk C, Amatruda JF, Munshi NV
Citation:
Dev Dyn. 2019 Feb;248(2):173-188. doi: 10.1002/dvdy.2. Epub 2018 Dec 10
Epub:
Not Epub
Abstract:
Background: Many human gene mutations have been linked to congenital heart disease (CHD), yet CHD remains a major health issue...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bhakta M, Padanad MS, Harris JP, Lubczyk C, Amatruda JF, Munshi NV. pouC Regulates Expression of bmp4 During Atrioventricular Canal Formation in Zebrafish. Dev Dyn. 2019 Feb;248(2):173-188. doi: 10.1002/dvdy.2. Epub 2018 Dec 10.

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