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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10798 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Distinct spatiotemporal contribution of morphogenetic events and mechanical tissue coupling during Xenopus neural tube closure

Authors:
Christodoulou N, Skourides PA
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.06.01.446407
Epub:
Not Epub
Abstract:
Neural tube closure (NTC) is a fundamental process during vertebrate embryonic development and is indispensable for the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Christodoulou N, Skourides PA. Distinct spatiotemporal contribution of morphogenetic events and mechanical tissue coupling during Xenopus neural tube closure. bioRxiv. 2021;[preprint] doi:10.1101/2021.06.01.446407 .

[Donepezil Reduces Amyloid Precursor Protein Endocytosis by Resulting from Increase in the Expression of Sorting Nexin Protein 33]

Authors:
Takada-Takatori Y
Citation:
Yakugaku Zasshi. 2021;141(6):851-856. doi:10.1248/yakushi.20-00251-6
Epub:
Not Epub
Abstract:
Donepezil, the most widely used drug for the treatment of Alzheimer's disease (AD), is an acetylcholinesterase (AChE)...
Organism or Cell Type:
cell culture: primary fetal rat cortical neurons
Citation Extract:
Takada-Takatori Y. [Donepezil Reduces Amyloid Precursor Protein Endocytosis by Resulting from Increase in the Expression of Sorting Nexin Protein 33]. Yakugaku Zasshi. 2021;141(6):851-856. doi:10.1248/yakushi.20-00251-6.

Masculinization of Zebrafish Through Partial Depletion of Primordial Germ Cells by Injecting Diluted Morpholino Oligonucleotides into Embryos

Authors:
Orbán L, Saju JM, Tzung KW, Liew WC
Citation:
In: Dosch R. (eds) Germline Development in the Zebrafish. Methods in Molecular Biology. 2021;2218. Humana, New York, NY. doi:10.1007/978-1-0716-0970-5_5
Epub:
Not Epub
Abstract:
The regulation of reproduction in zebrafish, the prime model of fish research, is not fully understood. An efficient tool to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Orbán L, Saju JM, Tzung KW, Liew WC. Masculinization of Zebrafish Through Partial Depletion of Primordial Germ Cells by Injecting Diluted Morpholino Oligonucleotides into Embryos. In: Dosch R. (eds) Germline Development in the Zebrafish. Methods in Molecular Biology. 2021;2218. Humana, New York, NY. doi:10.1007/978-1-0716-0970-5_5.

Myeloid-derived growth factor regulates neutrophil motility in interstitial tissue damage

Authors:
Houseright RA, Miskolci V, Mulvaney O, Bortnov V, Mosher DF, Rindy J, Bennin DA, Huttenlocher A
Citation:
J Cell Biol. 2021;220(8):e202103054. Epub ahead of print. doi:10.1083/jcb.202103054
Epub:
Not Epub
Abstract:
Neutrophil recruitment to tissue damage is essential for host defense but can also impede tissue repair. The cues that...
Organism or Cell Type:
zebrafish
Citation Extract:
Houseright RA, Miskolci V, Mulvaney O, Bortnov V, Mosher DF, Rindy J, Bennin DA, Huttenlocher A. Myeloid-derived growth factor regulates neutrophil motility in interstitial tissue damage. J Cell Biol. 2021;220(8):e202103054. Epub ahead of print. doi:10.1083/jcb.202103054.

A Novel BLOC1S5-Related HPS-11 Patient and Zebrafish with bloc1s5 Disruption

Authors:
Zhong Z, Wu Z, Zhang J, Chen J
Citation:
Pigment Cell Melanoma Res. 2021 May 31. doi: 10.1111/pcmr.12995. Online ahead of print
Epub:
Yes
Abstract:
HPS (Hermansky-Pudlak Syndrome) cases present with a variable degree of OCA and bleeding tendency. HPS is categorized into...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhong Z, Wu Z, Zhang J, Chen J. A Novel BLOC1S5-Related HPS-11 Patient and Zebrafish with bloc1s5 Disruption. Pigment Cell Melanoma Res. 2021 May 31. doi: 10.1111/pcmr.12995. Online ahead of print.

Claudin h Is Essential for Hair Cell Morphogenesis and Auditory Function in Zebrafish

Authors:
Gong J, Qian P, Hu Y, Guo C, Wei G, Wang C, Cai C, Wang H, Liu D
Citation:
Front Cell Dev Biol. 2021 May 11;9:663995. doi: 10.3389/fcell.2021.663995. eCollection 2021
Epub:
Not Epub
Abstract:
Hereditary hearing loss caused by defective hair cells is one of the most common congenital diseases, whose nosogenesis is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gong J, Qian P, Hu Y, Guo C, Wei G, Wang C, Cai C, Wang H, Liu D. Claudin h Is Essential for Hair Cell Morphogenesis and Auditory Function in Zebrafish. Front Cell Dev Biol. 2021 May 11;9:663995. doi: 10.3389/fcell.2021.663995. eCollection 2021.

Mvda is required for zebrafish early development

Authors:
Wong W, Huang Y, Wu Z, Kong Y, Luan J, Zhang Q, Pan J, Yan K, Zhang Z
Citation:
Biol Res. 2021 May 29;54(1):17. doi: 10.1186/s40659-021-00341-7
Epub:
Not Epub
Abstract:
Background: The MVD gene mutations are identified in porokeratosis, which is considered a skin-specific autoinflammatory...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wong W, Huang Y, Wu Z, Kong Y, Luan J, Zhang Q, Pan J, Yan K, Zhang Z. Mvda is required for zebrafish early development. Biol Res. 2021 May 29;54(1):17. doi: 10.1186/s40659-021-00341-7.

Biallelic and monoallelic variants in PLXNA1 are implicated in a novel neurodevelopmental disorder with variable cerebral and eye anomalies

Authors:
Dworschak GC, Punetha J, Kalanithy JC, Mingardo E, Erdem HB, Akdemir ZC, Karaca E, Mitani T, Marafi D, Fatih JM, Jhangiani SN, Hunter JV, Dakal TC, Dhabhai B, Dabbagh O, Alsaif HS, Alkuraya FS, Maroofian R, Houlden H, Efthymiou S, Dominik N, Salpietro V, Sultan T, Haider S, Bibi F, Thiele H, Hoefele J, Riedhammer KM, Wagner M, Guella I, Demos M, Keren B, Buratti J, Charles P, Nava C, Héron D, Heide S, Valkanas E, Waddell LB, Jones KJ, Oates EC, Cooper ST, MacArthur D, Syrbe S, Ziegler A, Platzer K, Okur V, Chung WK, O'Shea SA, Alcalay R, Fahn S, Mark PR, Guerrini R, Vetro A, Hudson B, Schnur RE, Hoganson GE, Burton JE, McEntagart M, Lindenberg T, Yilmaz Ö, Odermatt B, Pehlivan D, Posey JE, Lupski JR, Reutter H
Citation:
Genet Med. 2021 May 30. doi: 10.1038/s41436-021-01196-9. Online ahead of print
Epub:
Not Epub
Abstract:
Purpose: To investigate the effect of PLXNA1 variants on the phenotype of patients with autosomal dominant and recessive...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dworschak GC, Punetha J, Kalanithy JC, Mingardo E, Erdem HB, Akdemir ZC, Karaca E, Mitani T, Marafi D, Fatih JM, Jhangiani SN, Hunter JV, Dakal TC, Dhabhai B, Dabbagh O, Alsaif HS, Alkuraya FS, Maroofian R, Houlden H, Efthymiou S, Dominik N, Salpietro V, Sultan T, Haider S, Bibi F, Thiele H, Hoefele J, Riedhammer KM, Wagner M, Guella I, Demos M, Keren B, Buratti J, Charles P, Nava C, Héron D, Heide S, Valkanas E, Waddell LB, Jones KJ, Oates EC, Cooper ST, MacArthur D, Syrbe S, Ziegler A, Platzer K, Okur V, Chung WK, O'Shea SA, Alcalay R, Fahn S, Mark PR, Guerrini R, Vetro A, Hudson B, Schnur RE, Hoganson GE, Burton JE, McEntagart M, Lindenberg T, Yilmaz Ö, Odermatt B, Pehlivan D, Posey JE, Lupski JR, Reutter H. Biallelic and monoallelic variants in PLXNA1 are implicated in a novel neurodevelopmental disorder with variable cerebral and eye anomalies. Genet Med. 2021 May 30. doi: 10.1038/s41436-021-01196-9. Online ahead of print.

Genetic variant of TTLL11 gene and subsequent ciliary defects are associated with idiopathic scoliosis in a 5-generation UK family

Authors:
Mathieu H, Patten SA, Aragon-Martin JA, Ocaka L, Simpson M, Child A, Moldovan F
Citation:
Sci Rep. 2021 May 26;11(1):11026. doi: 10.1038/s41598-021-90155-0
Epub:
Not Epub
Abstract:
Idiopathic scoliosis (IS) is a complex 3D deformation of the spine with a strong genetic component, most commonly found in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mathieu H, Patten SA, Aragon-Martin JA, Ocaka L, Simpson M, Child A, Moldovan F. Genetic variant of TTLL11 gene and subsequent ciliary defects are associated with idiopathic scoliosis in a 5-generation UK family. Sci Rep. 2021 May 26;11(1):11026. doi: 10.1038/s41598-021-90155-0.

CX3CR1 is a Receptor for Human Respiratory Syncytial Virus in Cotton Rats

Authors:
Green G, Johnson SM, Costello H, Brakel K, Harder O, Oomens AG, Peeples ME, Moulton HM, Niewiesk S
Citation:
J Virol. 2021 May 26:JVI0001021. doi: 10.1128/JVI.00010-21. Online ahead of print
Epub:
Not Epub
Abstract:
Respiratory syncytial virus (RSV) has been reported to use CX3CR1 in vitro as a receptor on cultured primary human airway...
Delivery Method:
peptide-linked
Organism or Cell Type:
Sigmodon sp. (Cotton rat)
Citation Extract:
Green G, Johnson SM, Costello H, Brakel K, Harder O, Oomens AG, Peeples ME, Moulton HM, Niewiesk S. CX3CR1 is a Receptor for Human Respiratory Syncytial Virus in Cotton Rats. J Virol. 2021 May 26:JVI0001021. doi: 10.1128/JVI.00010-21. Online ahead of print.

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