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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9561 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Efficient generation of zebrafish maternal-zygotic mutants through transplantation of ectopically induced and Cas9/gRNA targeted PGCs

Authors:
Zhang F, Li X, He M, Ye D, Xiong F, Amin G, Zhu Z, Sun Y
Citation:
bioRxiv. 2019:[preprint] doi:10.1101/693853
Abstract:
The CRISPR/Cas9 technology has been widely utilized for knocking out genes involved in various biological processes in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang F, Li X, He M, Ye D, Xiong F, Amin G, Zhu Z, Sun Y. Efficient generation of zebrafish maternal-zygotic mutants through transplantation of ectopically induced and Cas9/gRNA targeted PGCs. bioRxiv. 2019:[preprint] doi:10.1101/693853 .

Evolution of abbreviated development in Heliocidaris erythrogramma dramatically re-wired the highly conserved sea urchin developmental gene regulatory network to decouple signaling center function from ultimate fate

Authors:
Edgar A, Byrnev M, McClay DR, Wray GA
Citation:
bioRxiv. 2019:[preprint] doi:10.1101/712216
Abstract:
Developmental gene regulatory networks (GRNs) describe the interactions among gene products that drive the differential...
Delivery Method:
microinjection
Organism or Cell Type:
Heliocidaris erythrogramma (sea urchin)
Citation Extract:
Edgar A, Byrnev M, McClay DR, Wray GA. Evolution of abbreviated development in Heliocidaris erythrogramma dramatically re-wired the highly conserved sea urchin developmental gene regulatory network to decouple signaling center function from ultimate fate. bioRxiv. 2019:[preprint] doi:10.1101/712216.

Gclc deletion in surface-ectoderm tissues induces microphthalmia

Authors:
Thompson B, Chen Y, Philippe J, Anderson D, Golla JP, Davidson E, Apostolopoulos N, Schey K, Katsanis N, Orlicky DJ, Thompson D, Vasiliou V
Citation:
bioRxiv. 2019:[preprint]. doi:10.1101/700591
Abstract:
Glutamate cysteine ligase catalytic subunit (Gclc) is the catalytic subunit for the glutamate-cysteine ligase (Gcl) enzyme. Gcl...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thompson B, Chen Y, Philippe J, Anderson D, Golla JP, Davidson E, Apostolopoulos N, Schey K, Katsanis N, Orlicky DJ, Thompson D, Vasiliou V. Gclc deletion in surface-ectoderm tissues induces microphthalmia. bioRxiv. 2019:[preprint]. doi:10.1101/700591.

Planar Polarization of Cilia in the Zebrafish Floor Plate Involves Par3-Mediated Posterior Localization of Highly Motile Basal Bodies

Authors:
Donati A, Schneider-Maunoury S, Vesque C
Citation:
bioRxiv. 2019:[preprint] doi:10.1101/702282
Abstract:
To produce a directional flow, ciliated epithelia display a uniform orientation of ciliary beating. Oriented beating requires...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Donati A, Schneider-Maunoury S, Vesque C. Planar Polarization of Cilia in the Zebrafish Floor Plate Involves Par3-Mediated Posterior Localization of Highly Motile Basal Bodies. bioRxiv. 2019:[preprint] doi:10.1101/702282.

Greb1 is required for axial elongation and segmentation in vertebrate embryos

Authors:
Prajapati RS, Mitter R, Vezzaro A, Ish-Horowicz D
Citation:
bioRxiv. 2019:[preprint] doi:10.1101/692095
Abstract:
During vertebrate embryonic development, the formation of axial structures is driven by a population of stem-like cells that...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prajapati RS, Mitter R, Vezzaro A, Ish-Horowicz D. Greb1 is required for axial elongation and segmentation in vertebrate embryos. bioRxiv. 2019:[preprint] doi:10.1101/692095.

Sensory neurogenesis depends on vascular-neuronal cytoneme contacts and blood flow

Authors:
Taberner L, Bañón A, Alsina B
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/667519
Abstract:
Cranial sensory neurons develop in close proximity to blood vessels, however the neurovascular interactions in the cranial...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Taberner L, Bañón A, Alsina B. Sensory neurogenesis depends on vascular-neuronal cytoneme contacts and blood flow. bioRxiv. 2019;[preprint] doi:10.1101/667519 .

Histone code dictates fate biasing of neural crest cells to melanocyte lineage

Authors:
Raja DA, Subramaniam Y, Gotherwal V, Tanwar J, Motiani R, Sivasubbu S, Gokhale RS, Natarajan VT
Citation:
bioRxiv. 2019;[preprint]. doi:10.1101/702332
Abstract:
In the neural crest lineage, progressive fate-restriction and stem cell assignment are critical for both development and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Raja DA, Subramaniam Y, Gotherwal V, Tanwar J, Motiani R, Sivasubbu S, Gokhale RS, Natarajan VT. Histone code dictates fate biasing of neural crest cells to melanocyte lineage. bioRxiv. 2019;[preprint]. doi:10.1101/702332 .

Intracellular enhancement of BMP signaling by LIM-domain protein FHL3 controls spatiotemporal emergence of the neural crest driven by WNT signaling

Authors:
Alkobtawi M, Pla P, Monsoro-Burq AH
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/711192
Abstract:
How multiple morphogen signals are coordinated in space and time to position key embryonic tissues remains elusive. During...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Alkobtawi M, Pla P, Monsoro-Burq AH. Intracellular enhancement of BMP signaling by LIM-domain protein FHL3 controls spatiotemporal emergence of the neural crest driven by WNT signaling. bioRxiv. 2019;[preprint] doi:10.1101/711192.

Deficiency in the endocytic adaptor protein PHETA1/2 impairs renal and craniofacial development

Authors:
Ates KM, Wang T, Moreland T, Veeranan-Karmegam R, Anand P, Wenzel W, Kim H-G, Wolfe LA, Stephen JA, Adams DR, Markello T, Tifft CJ, Gahl WA, Gonsalvez GB, May Christine Malicdan, Flanagan-Steet H, Pan Y
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/727578
Abstract:
A critical barrier in the treatment of endosomal and lysosomal diseases is the lack of understanding of the in vivo functions...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ates KM, Wang T, Moreland T, Veeranan-Karmegam R, Anand P, Wenzel W, Kim H-G, Wolfe LA, Stephen JA, Adams DR, Markello T, Tifft CJ, Gahl WA, Gonsalvez GB, May Christine Malicdan, Flanagan-Steet H, Pan Y. Deficiency in the endocytic adaptor protein PHETA1/2 impairs renal and craniofacial development. bioRxiv. 2019;[preprint] doi:10.1101/727578.

NAD+ improves neuromuscular development in a zebrafish model of FKRP-associated dystroglycanopathy

Authors:
Bailey EC, Alrowaished SS, Kilroy EA, Crooks ES, Drinkert DM, Karunasiri CM, Belanger JJ, Khalil A, Kelley JB, Henry CA
Citation:
Skeletal Musc. 2019;9:21. doi:10.1186/s13395-019-0206-1
Abstract:
Background: Secondary dystroglycanopathies are muscular dystrophies that result from mutations in genes that participate in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bailey EC, Alrowaished SS, Kilroy EA, Crooks ES, Drinkert DM, Karunasiri CM, Belanger JJ, Khalil A, Kelley JB, Henry CA. NAD+ improves neuromuscular development in a zebrafish model of FKRP-associated dystroglycanopathy. Skeletal Musc. 2019;9:21. doi:10.1186/s13395-019-0206-1.

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