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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10468 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Robust Filtering and Noise Suppression in Intragenic miRNA-Mediated Host Regulation

Authors:
Kang T, Quarton T, Nowak CM, Ehrhardt K, Singh A, Li Y, Bleris L
Citation:
iScience. 2020 Sep 21;23(10):101595. doi: 10.1016/j.isci.2020.101595. eCollection 2020 Oct 23
Abstract:
MicroRNAs (miRNAs) are short non-coding RNA molecules that regulate gene expression post-transcriptionally by binding to target...
Organism or Cell Type:
cell culture: HEK293
Citation Extract:
Kang T, Quarton T, Nowak CM, Ehrhardt K, Singh A, Li Y, Bleris L. Robust Filtering and Noise Suppression in Intragenic miRNA-Mediated Host Regulation. iScience. 2020 Sep 21;23(10):101595. doi: 10.1016/j.isci.2020.101595. eCollection 2020 Oct 23.

Identification of novel susceptibility loci for non-syndromic cleft lip with or without cleft palate

Authors:
Ma L, Lou S, Miao Z, Yao S, Yu X, Kan S, Zhu G, Yang F, Zhang C, Zhang W, Wang M, Wang L, Pan Y
Citation:
J Cell Mol Med. 2020 Oct 27. doi: 10.1111/jcmm.15878. Online ahead of print
Abstract:
Although several genome-wide association studies (GWAS) of non-syndromic cleft lip with or without cleft palate (NSCL/P) have...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ma L, Lou S, Miao Z, Yao S, Yu X, Kan S, Zhu G, Yang F, Zhang C, Zhang W, Wang M, Wang L, Pan Y. Identification of novel susceptibility loci for non-syndromic cleft lip with or without cleft palate. J Cell Mol Med. 2020 Oct 27. doi: 10.1111/jcmm.15878. Online ahead of print.

X-box-binding protein 1 is required for pancreatic development in Xenopus laevis

Authors:
Yang J, Liu X, Yuan F, Liu J, Li D, Wei L, Wang X, Yuan L
Citation:
Acta Biochim Biophys Sin (Shanghai). 2020 Oct 24:gmaa114. doi: 10.1093/abbs/gmaa114. Online ahead of print
Abstract:
X-box-binding protein 1 (XBP1) is a protein containing the basic leucine zipper structure. It belongs to the cAMP-response...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yang J, Liu X, Yuan F, Liu J, Li D, Wei L, Wang X, Yuan L. X-box-binding protein 1 is required for pancreatic development in Xenopus laevis. Acta Biochim Biophys Sin (Shanghai). 2020 Oct 24:gmaa114. doi: 10.1093/abbs/gmaa114. Online ahead of print.

Use of a carbonic anhydrase ca17a knockout to investigate mechanisms of ion uptake in zebrafish (Danio rerio)

Authors:
Zimmer AM, Mandic M, Yew HM, Kunert E, Pan YK, Ha J, Kwong RWM, Gilmour KM, Perry SF
Citation:
Am J Physiol Regul Integr Comp Physiol. 2020 Oct 21. doi: 10.1152/ajpregu.00215.2020. Online ahead of print
Abstract:
In fishes, branchial cytosolic carbonic anhydrase (CA) plays an important role in ion and acid-base regulation. The Ca17a...
Organism or Cell Type:
zebrafish
Citation Extract:
Zimmer AM, Mandic M, Yew HM, Kunert E, Pan YK, Ha J, Kwong RWM, Gilmour KM, Perry SF. Use of a carbonic anhydrase ca17a knockout to investigate mechanisms of ion uptake in zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2020 Oct 21. doi: 10.1152/ajpregu.00215.2020. Online ahead of print.

Aconitine disrupts serotonin neurotransmission via 5-hydroxytryptamine receptor in zebrafish embryo

Authors:
Chen H, Wang F, Ni X, Rigui Y, Bai Y, Xu L, Yang J, Zhang X, Deng J, Li J, Yin X, Ao W, Kwok KWH, Dong W
Citation:
J Appl Toxicol. 2020 Oct 21. doi: 10.1002/jat.4059. Online ahead of print
Abstract:
Medicinal plants of the genus Aconitum are one of the most commonly used herbs in traditional medicine in East Asia to treat...
Organism or Cell Type:
zebrafish
Citation Extract:
Chen H, Wang F, Ni X, Rigui Y, Bai Y, Xu L, Yang J, Zhang X, Deng J, Li J, Yin X, Ao W, Kwok KWH, Dong W. Aconitine disrupts serotonin neurotransmission via 5-hydroxytryptamine receptor in zebrafish embryo. J Appl Toxicol. 2020 Oct 21. doi: 10.1002/jat.4059. Online ahead of print.

A novel Golgi-associated Vangl2 translational variant required for PCP regulation in vertebrates

Authors:
Walton A, Revinski D, Serge A, Audebert S, Camoin L, Puvirajesinghe TM, Isnardon D, Marchetto S, Kodjabachian L, Bailly E, Borg J-P
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.10.20.347385
Abstract:
First described in Drosophila melanogaster, planar cell polarity (PCP) is a developmental process essential for embryogenesis...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Walton A, Revinski D, Serge A, Audebert S, Camoin L, Puvirajesinghe TM, Isnardon D, Marchetto S, Kodjabachian L, Bailly E, Borg J-P. A novel Golgi-associated Vangl2 translational variant required for PCP regulation in vertebrates. bioRxiv. 2020;[preprint] doi:10.1101/2020.10.20.347385 .

Effect of Mutated ids Overexpression on IDS Enzyme Activity and Developmental Phenotypes in Zebrafish Embryos: A Valuable Index for Assessing Critical Point-Mutations Associated with Mucopolysaccharidosis Type II Occurrence in Humans

Authors:
Lin C-Y, Lin H-Y, Chuang C-K, Zhang P-H, Tu 4 R-Y, Lin S-P, Tsai H-J
Citation:
Diagnostics. 2020;10(10):854 doi:10.3390/diagnostics10100854
Abstract:
Mucopolysaccharidosis type II (MPS II) is an X-linked disorder resulting from a deficiency in iduronate 2-sulfatase (IDS),...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin C-Y, Lin H-Y, Chuang C-K, Zhang P-H, Tu 4 R-Y, Lin S-P, Tsai H-J. Effect of Mutated ids Overexpression on IDS Enzyme Activity and Developmental Phenotypes in Zebrafish Embryos: A Valuable Index for Assessing Critical Point-Mutations Associated with Mucopolysaccharidosis Type II Occurrence in Humans. Diagnostics. 2020;10(10):854 doi:10.3390/diagnostics10100854.

The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models

Authors:
Klems A, van Rijssel J, Ramms AS, Wild R, Hammer J, Merkel M, Derenbach L, Préau L, Hinkel R, Suarez-Martinez I, Schulte-Merker S, Vidal R, Sauer S, Kivelä R, Alitalo K, Kupatt C, van Buul JD, le Noble F
Citation:
Nat Comm. 2020;11(1):5319. doi:10.1038/s41467-020-19008-0
Abstract:
Arterial networks enlarge in response to increase in tissue metabolism to facilitate flow and nutrient delivery. Typically, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Klems A, van Rijssel J, Ramms AS, Wild R, Hammer J, Merkel M, Derenbach L, Préau L, Hinkel R, Suarez-Martinez I, Schulte-Merker S, Vidal R, Sauer S, Kivelä R, Alitalo K, Kupatt C, van Buul JD, le Noble F. The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models. Nat Comm. 2020;11(1):5319. doi:10.1038/s41467-020-19008-0.

Slc39a5-mediated zinc homeostasis plays an essential role in venous angiogenesis in zebrafish

Authors:
Xia Z, Bi X, Lian J, Dai W, He X, Zhao L, Min J, Wang F
Citation:
Open Biol. 2020 Oct;10(10):200281. doi: 10.1098/rsob.200281. Epub 2020 Oct 21
Abstract:
Angiogenesis is a precise process mediated by a variety of signals and the environmental niche. Although the essential trace...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xia Z, Bi X, Lian J, Dai W, He X, Zhao L, Min J, Wang F. Slc39a5-mediated zinc homeostasis plays an essential role in venous angiogenesis in zebrafish. Open Biol. 2020 Oct;10(10):200281. doi: 10.1098/rsob.200281. Epub 2020 Oct 21.

Visualisation of cholesterol and ganglioside GM1 in zebrafish models of Niemann-Pick type C disease and Smith-Lemli-Opitz syndrome using light sheet microscopy

Authors:
Cook SR, Bladen C, Smith J, Maguire E, Copner J, Fenn GD, Wager K, Waller-Evans H, Lloyd-Evans E
Citation:
Histochem Cell Biol. 2020 Oct 20. doi: 10.1007/s00418-020-01925-2. Online ahead of print
Abstract:
Lysosomal storage diseases are the most common cause of neurodegeneration in children. They are characterised at the cellular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cook SR, Bladen C, Smith J, Maguire E, Copner J, Fenn GD, Wager K, Waller-Evans H, Lloyd-Evans E. Visualisation of cholesterol and ganglioside GM1 in zebrafish models of Niemann-Pick type C disease and Smith-Lemli-Opitz syndrome using light sheet microscopy. Histochem Cell Biol. 2020 Oct 20. doi: 10.1007/s00418-020-01925-2. Online ahead of print.

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