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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11377 scientific papers returned from the database with the search filters currently being used below.

Essential Role of RIG-I in Hematopoietic Precursor Emergence in Primitive Hematopoiesis during Zebrafish Development

Authors:
Wang YY, Nie L, Xu XX, Shao T, Fan DD, Lin AF, Xiang LX, Shao JZ
Citation:
Immunohorizons. 2022 May 19;6(5):283-298. doi: 10.4049/immunohorizons.2200028
Epub:
Not Epub
Abstract:
Retinoic acid-inducible gene I (RIG-I) is an important cytosolic pattern recognition receptor crucial for sensing RNA virus...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang YY, Nie L, Xu XX, Shao T, Fan DD, Lin AF, Xiang LX, Shao JZ. Essential Role of RIG-I in Hematopoietic Precursor Emergence in Primitive Hematopoiesis during Zebrafish Development. Immunohorizons. 2022 May 19;6(5):283-298. doi: 10.4049/immunohorizons.2200028.

Huang Y, Winklbauer R

Authors:
Cell cortex regulation by the planar cell polarity protein Prickle1
Citation:
J Cell Biol. 2022 Jul 4;221(7):e202008116. doi: 10.1083/jcb.202008116. Epub 2022 May 5
Epub:
Not Epub
Abstract:
The planar cell polarity pathway regulates cell polarity, adhesion, and rearrangement. Its cytoplasmic core components Prickle...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Cell cortex regulation by the planar cell polarity protein Prickle1. Huang Y, Winklbauer R. J Cell Biol. 2022 Jul 4;221(7):e202008116. doi: 10.1083/jcb.202008116. Epub 2022 May 5.

Enhancement of Regnase-1 expression with stem loop-targeting antisense oligonucleotides alleviates inflammatory diseases

Authors:
Tse KM, Vandenbon A, Cui X, Mino T, Uehata T, Yasuda K, Sato A, Tsujimura T, Hia F, Yoshinaga M, Kinoshita M, Okuno T, Takeuchi O
Citation:
Sci Transl Med. 2022 May 11;14(644):eabo2137. doi: 10.1126/scitranslmed.abo2137. Epub 2022 May 11
Epub:
Not Epub
Abstract:
Regnase-1 is an ribonuclease that plays essential roles in restricting inflammation through degrading messenger RNAs (mRNAs)...
Delivery Method:
intratracheal, intracranial injection, Endo-Porter, Vivo-Morpholino
Organism or Cell Type:
mice, cell culture: HeLa, Raw264.7, mouse peritoneal macrophages, murine bone marrow-derived macrophages (BMDMs), murine CD4+ T cells
Citation Extract:
Tse KM, Vandenbon A, Cui X, Mino T, Uehata T, Yasuda K, Sato A, Tsujimura T, Hia F, Yoshinaga M, Kinoshita M, Okuno T, Takeuchi O. Enhancement of Regnase-1 expression with stem loop-targeting antisense oligonucleotides alleviates inflammatory diseases. Sci Transl Med. 2022 May 11;14(644):eabo2137. doi: 10.1126/scitranslmed.abo2137. Epub 2022 May 11.

Extracellular vesicles rich in HAX1 promote angiogenesis by modulating ITGB6 translation

Authors:
You B, Pan S, Gu M, Zhang K, Xia T, Zhang S, Chen W, Xie H, Fan Y, Yao H, Cheng T, Zhang P, Liu D, You Y
Citation:
J Extracell Vesicles. 2022 May;11(5):e12221. doi: 10.1002/jev2.12221
Epub:
Not Epub
Abstract:
Tumour-associated angiogenesis plays a critical role in metastasis, the main cause of malignancy-related death. Extracellular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
You B, Pan S, Gu M, Zhang K, Xia T, Zhang S, Chen W, Xie H, Fan Y, Yao H, Cheng T, Zhang P, Liu D, You Y. Extracellular vesicles rich in HAX1 promote angiogenesis by modulating ITGB6 translation. J Extracell Vesicles. 2022 May;11(5):e12221. doi: 10.1002/jev2.12221.

RanBP1 plays an essential role in directed migration of neural crest cells during development

Authors:
Barriga EH, Alasaadi DN, Mencarelli C, Mayor R, Pichaud F
Citation:
bioRxiv. 2022:490747. doi:10.1101/2022.05.05.490747
Epub:
Not Epub
Abstract:
Collective cell migration is essential for embryonic development, tissue regeneration and repair, and has been implicated in...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Barriga EH, Alasaadi DN, Mencarelli C, Mayor R, Pichaud F. RanBP1 plays an essential role in directed migration of neural crest cells during development. bioRxiv. 2022:490747. doi:10.1101/2022.05.05.490747 .

Wnt11 acts on dermomyotome cells to guide epaxial myotome morphogenesis

Authors:
Heilig AK, Nakamura R, Shimada A, Hashimoto Y, Nakamura Y, Wittbrodt J, Takeda H, Kawanishi T
Citation:
eLife. 2022;11:e71845. doi:10.7554/eLife.71845
Epub:
Not Epub
Abstract:
The dorsal axial muscles, or epaxial muscles, are a fundamental structure covering the spinal cord and vertebrae, as well as...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Heilig AK, Nakamura R, Shimada A, Hashimoto Y, Nakamura Y, Wittbrodt J, Takeda H, Kawanishi T. Wnt11 acts on dermomyotome cells to guide epaxial myotome morphogenesis. eLife. 2022;11:e71845. doi:10.7554/eLife.71845.

Cingulin b Is Required for Zebrafish Lateral Line Development Through Regulation of Mitogen-Activated Protein Kinase and Cellular Senescence Signaling Pathways

Authors:
Lu Y, Tang D, Zheng Z, Wang X, Zuo N, Yan R, Wu C, Ma J, Wang C, Xu H, He Y, Liu D, Liu S
Citation:
Front Mol Neurosci. 2022;15:844668. doi:10.3389/fnmol.2022.844668
Epub:
Not Epub
Abstract:
Cingulin, a cytoplasmic element of tight junctions (TJs), is involved in maintenance of the integrity of epithelial and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu Y, Tang D, Zheng Z, Wang X, Zuo N, Yan R, Wu C, Ma J, Wang C, Xu H, He Y, Liu D, Liu S. Cingulin b Is Required for Zebrafish Lateral Line Development Through Regulation of Mitogen-Activated Protein Kinase and Cellular Senescence Signaling Pathways. Front Mol Neurosci. 2022;15:844668. doi:10.3389/fnmol.2022.844668.

Role of suppressing GLT-1 and xCT in ceftriaxone-induced attenuation of relapse-like alcohol drinking in alcohol-preferring rats

Authors:
Das SC, Althobaiti YS, Hammad AM, Alasmari F, Sari Y
Citation:
Addict Biol. 2022;[Epub] doi:10.1111/adb.13178
Epub:
Yes
Abstract:
Alcohol dependence results in long-lasting neuroadaptive changes in meso-corticolimbic system, especially in the nucleus...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
rat
Citation Extract:
Das SC, Althobaiti YS, Hammad AM, Alasmari F, Sari Y. Role of suppressing GLT-1 and xCT in ceftriaxone-induced attenuation of relapse-like alcohol drinking in alcohol-preferring rats. Addict Biol. 2022;[Epub] doi:10.1111/adb.13178.

Aldh2 is a lineage-specific metabolic gatekeeper in melanocyte stem cells

Authors:
Brunsdon H, Brombin A, Peterson S, Postlethwait JH, Patton EE
Citation:
Development. 2022 Apr 29:dev.200277. doi: 10.1242/dev.200277. Online ahead of print
Epub:
Not Epub
Abstract:
Melanocyte stem cells (McSCs) in zebrafish serve as an on-demand source of melanocytes during growth and regeneration, but...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brunsdon H, Brombin A, Peterson S, Postlethwait JH, Patton EE. Aldh2 is a lineage-specific metabolic gatekeeper in melanocyte stem cells. Development. 2022 Apr 29:dev.200277. doi: 10.1242/dev.200277. Online ahead of print.

Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration

Authors:
Porpiglia E, Mai T, Kraft P, Holbrook CA, de Morree A, Gonzalez VD, Hilgendorf K, Fresard L, Trejo A, Bhimaraju S, Jackson PK, Fantl WJ, Blau HM
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.04.29.489435
Epub:
Not Epub
Abstract:
In aging, skeletal muscle strength and regenerative capacity declines due, in part, to functional impairment of muscle stem...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: muscle stem cells
Citation Extract:
Porpiglia E, Mai T, Kraft P, Holbrook CA, de Morree A, Gonzalez VD, Hilgendorf K, Fresard L, Trejo A, Bhimaraju S, Jackson PK, Fantl WJ, Blau HM. Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration. bioRxiv. 2022;[preprint] doi:10.1101/2022.04.29.489435.

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