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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9382 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

FoxN3 is necessary for the development of the interatrial septum, the ventricular trabeculae and the muscles at the head/trunk interface in the African clawed frog, Xenopus laevis (Lissamphibia: Anura: Pipidae)

Authors:
Naumann B, Schmidt J, Olsson L
Citation:
Dev Dyn. 2019 Mar 11. doi: 10.1002/dvdy.25. [Epub ahead of print]
Abstract:
BACKGROUND: Fox genes are a large family of transcription factors that play diverse roles in the immune system, metabolism,...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Naumann B, Schmidt J, Olsson L. FoxN3 is necessary for the development of the interatrial septum, the ventricular trabeculae and the muscles at the head/trunk interface in the African clawed frog, Xenopus laevis (Lissamphibia: Anura: Pipidae). Dev Dyn. 2019 Mar 11. doi: 10.1002/dvdy.25. [Epub ahead of print].

The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1

Authors:
Ott T, Kaufmann L, Granzow M, Hinderhofer K, Bartram CR, Theiß S, Seitz A, Paramasivam N, Schulz A, Moog U, Blum M, Evers CM
Citation:
Front Physiol. 2019 Feb 25;10:134. doi: 10.3389/fphys.2019.00134. eCollection 2019
Abstract:
Joubert syndrome (JS) is a congenital autosomal-recessive or-in rare cases-X-linked inherited disease. The diagnostic hallmark...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ott T, Kaufmann L, Granzow M, Hinderhofer K, Bartram CR, Theiß S, Seitz A, Paramasivam N, Schulz A, Moog U, Blum M, Evers CM. The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1. Front Physiol. 2019 Feb 25;10:134. doi: 10.3389/fphys.2019.00134. eCollection 2019.

Ultrasensitive detection of microRNA using an array of Au nanowires deposited within the channels of a porous anodized alumina membrane

Authors:
Li C, He L, Jiang S, Mo R, Yan X, Qian Z-J, Zhou C, Sun S, Hong P, Huang Y
Citation:
Elecrochem Comm. 2019;[Epub ahead of print] doi:10.1016/j.elecom.2019.03.008
Abstract:
A new nanopore array/Au electrode was fabricated and applied to the detection of microRNA. The electrode was prepared via...
Citation Extract:
Li C, He L, Jiang S, Mo R, Yan X, Qian Z-J, Zhou C, Sun S, Hong P, Huang Y. Ultrasensitive detection of microRNA using an array of Au nanowires deposited within the channels of a porous anodized alumina membrane. Elecrochem Comm. 2019;[Epub ahead of print] doi:10.1016/j.elecom.2019.03.008.

Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly

Authors:
Lahrouchi N, George A, Ratbi I, Schneider R, Elalaoui SC, Moosa S, Bharti S, Sharma R, Abu-Asab M, Onojafe F, Adadi N, Lodder EM, Laarabi F-Z, Lamsyah Y, Elorch H, Chebbar I, Postma AV, Lougaris V, Plebani A, Altmueller J, Kyrieleis H, Meiner V, McNeill H, Bharti K, Lyonnet S, Wollnik B, Henrion-Caude A, Berraho A, Hildebrandt F, Bezzina CR, Brooks BP, Sefiani A
Citation:
Nat Comm. 2019;10:1180. doi:10.1038/s41467-019-08547-w
Abstract:
A failure in optic fissure fusion during development can lead to blinding malformations of the eye. Here, we report a syndrome...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lahrouchi N, George A, Ratbi I, Schneider R, Elalaoui SC, Moosa S, Bharti S, Sharma R, Abu-Asab M, Onojafe F, Adadi N, Lodder EM, Laarabi F-Z, Lamsyah Y, Elorch H, Chebbar I, Postma AV, Lougaris V, Plebani A, Altmueller J, Kyrieleis H, Meiner V, McNeill H, Bharti K, Lyonnet S, Wollnik B, Henrion-Caude A, Berraho A, Hildebrandt F, Bezzina CR, Brooks BP, Sefiani A. Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly. Nat Comm. 2019;10:1180. doi:10.1038/s41467-019-08547-w.

Loss of foxc1 in zebrafish reduces optic nerve size and cell number in the retinal ganglion cell layer

Authors:
Umali J, Hawkey-Noble A, French CR
Citation:
Vision Res. 2019 Mar;156:66-72. doi: 10.1016/j.visres.2019.01.008. Epub 2019 Feb 2
Abstract:
Mutation of FOXC1 causes Axenfeld-Rieger Syndrome (ARS) with early onset or congenital glaucoma. We assessed retinal ganglion...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Umali J, Hawkey-Noble A, French CR. Loss of foxc1 in zebrafish reduces optic nerve size and cell number in the retinal ganglion cell layer. Vision Res. 2019 Mar;156:66-72. doi: 10.1016/j.visres.2019.01.008. Epub 2019 Feb 2.

Proteasomal inhibition attenuates craniofacial malformations in a zebrafish model of Treacher Collins Syndrome

Authors:
Rosas MG, Lorenzatti A, de Peralta MSP, Calcatera NB, Coux G
Citation:
Biochem Pharmacol. 2019 Mar 5. pii: S0006-2952(19)30091-7. doi: 10.1016/j.bcp.2019.03.005. [Epub ahead of print]
Abstract:
Treacher Collins Syndrome (TCS) is a congenital disease characterized by defects in the craniofacial skeleton and absence of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rosas MG, Lorenzatti A, de Peralta MSP, Calcatera NB, Coux G. Proteasomal inhibition attenuates craniofacial malformations in a zebrafish model of Treacher Collins Syndrome. Biochem Pharmacol. 2019 Mar 5. pii: S0006-2952(19)30091-7. doi: 10.1016/j.bcp.2019.03.005. [Epub ahead of print].

Modelling Duchenne muscular dystrophy in MYOD1-converted urine-derived cells treated with 3-deazaneplanocin A hydrochloride

Authors:
Takizawa H, Hara Y, Mizobe Y, Ohno T, Suzuki S, Inoue K, Takeshita E, Shimizu-Motohashi Y, Ishiyama A, Hoshino M, Komaki H, Takeda S, Aoki Y
Citation:
Sci Rep. 2019;9(1):3807. doi:10.1038/s41598-019-40421-z
Abstract:
Duchenne muscular dystrophy (DMD) is a severe muscle disorder characterised by mutations in the DMD gene. Recently, we have...
Delivery Method:
Endo-Porter
Organism or Cell Type:
human MYOD1-urine-derived cells and MYOD1-converted fibroblasts
Citation Extract:
Takizawa H, Hara Y, Mizobe Y, Ohno T, Suzuki S, Inoue K, Takeshita E, Shimizu-Motohashi Y, Ishiyama A, Hoshino M, Komaki H, Takeda S, Aoki Y. Modelling Duchenne muscular dystrophy in MYOD1-converted urine-derived cells treated with 3-deazaneplanocin A hydrochloride. Sci Rep. 2019;9(1):3807. doi:10.1038/s41598-019-40421-z.

bif1, a new BMP signaling inhibitor, regulates embryonic hematopoiesis in the zebrafish

Authors:
Ghersi JJ, Mahony CB, Bertrand JY
Citation:
Development. 2019;dev.164103. doi:10.1242/dev.164103
Abstract:
Hematopoiesis maintains the entire blood system and dysregulation of this process can lead to malignancies (leukemia),...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ghersi JJ, Mahony CB, Bertrand JY. bif1, a new BMP signaling inhibitor, regulates embryonic hematopoiesis in the zebrafish. Development. 2019;dev.164103. doi:10.1242/dev.164103.

Etv6 activates vegfa expression through positive and negative transcriptional regulatory networks in Xenopus embryos

Authors:
Li L, Rispoli R, Patient R, Ciau-Uitz A, Porcher C
Citation:
Nat Commun. 2019 Mar 6;10(1):1083. doi: 10.1038/s41467-019-09050-y
Abstract:
VEGFA signaling controls physiological and pathological angiogenesis and hematopoiesis. Although many context-dependent...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Li L, Rispoli R, Patient R, Ciau-Uitz A, Porcher C. Etv6 activates vegfa expression through positive and negative transcriptional regulatory networks in Xenopus embryos. Nat Commun. 2019 Mar 6;10(1):1083. doi: 10.1038/s41467-019-09050-y.

L1cam-mediated developmental processes of the nervous system are differentially regulated by proteolytic processing

Authors:
Linneberg C, Toft CLF, Kjaer-Sorensen K, Laursen LS
Citation:
Sci Rep. 2019 Mar 6;9(1):3716. doi: 10.1038/s41598-019-39884-x
Abstract:
Normal brain development depends on tight temporal and spatial regulation of connections between cells. Mutations in L1cam, a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Linneberg C, Toft CLF, Kjaer-Sorensen K, Laursen LS. L1cam-mediated developmental processes of the nervous system are differentially regulated by proteolytic processing. Sci Rep. 2019 Mar 6;9(1):3716. doi: 10.1038/s41598-019-39884-x.

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