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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9561 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Tfap2a is a novel gatekeeper of nephron differentiation during kidney development

Authors:
Chambers BE, Gerlach GF, Clark EG, Chen KH, Levesque AE, Leshchiner I, Goessling W, Wingert RA
Citation:
Development. 2019 Jun 3. pii: dev.172387. doi: 10.1242/dev.172387. [Epub ahead of print]
Abstract:
Renal functional units known as nephrons undergo patterning events during development that create a segmental array of cellular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chambers BE, Gerlach GF, Clark EG, Chen KH, Levesque AE, Leshchiner I, Goessling W, Wingert RA. Tfap2a is a novel gatekeeper of nephron differentiation during kidney development. Development. 2019 Jun 3. pii: dev.172387. doi: 10.1242/dev.172387. [Epub ahead of print].

Notch-mediated inhibition of neurogenesis is required for zebrafish spinal cord morphogenesis

Authors:
Sharma P, Saraswathy VM, Xiang L, Fürthauer M
Citation:
Sci Rep. 2019;9(1):9958. doi:10.1038/s41598-019-46067-1
Abstract:
The morphogenesis of the nervous system requires coordinating the specification and differentiation of neural precursor cells,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sharma P, Saraswathy VM, Xiang L, Fürthauer M. Notch-mediated inhibition of neurogenesis is required for zebrafish spinal cord morphogenesis. Sci Rep. 2019;9(1):9958. doi:10.1038/s41598-019-46067-1.

Heroin Cue-Evoked Astrocytic Structural Plasticity at Nucleus Accumbens Synapses Inhibits Heroin Seeking

Authors:
Kruyer A, Scofield MD, Wood D, Reissner KJ, Kalivas PW
Citation:
Biol Psych. 2019;[Epub ahead of print] doi:10.1016/j.biopsych.2019.06.026
Abstract:
Background: Opioid addiction is a critical medical and social problem characterized by vulnerability to relapse. Glutamatergic...
Delivery Method:
bilateral NAcore brain infusion Vivo-Morpholino
Organism or Cell Type:
Rats Sprague-Dawley male
Citation Extract:
Kruyer A, Scofield MD, Wood D, Reissner KJ, Kalivas PW. Heroin Cue-Evoked Astrocytic Structural Plasticity at Nucleus Accumbens Synapses Inhibits Heroin Seeking. Biol Psych. 2019;[Epub ahead of print] doi:10.1016/j.biopsych.2019.06.026.

The role of maternal pioneer factors in predefining first zygotic responses to inductive signals

Authors:
Gentsch GE, Spruce T, Owens NDL, Smith JC
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/306803
Abstract:
Embryonic development yields many different cell types in response to just a few families of inductive signals. The property of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Gentsch GE, Spruce T, Owens NDL, Smith JC. The role of maternal pioneer factors in predefining first zygotic responses to inductive signals. bioRxiv. 2019;[preprint] doi:10.1101/306803 .

The lncRNAs Implicated in Redox Regulation in Ybx1 Deficient Zebrafish Larvae

Authors:
Huang C, Zhu B, Leng D, Ge W, Zhang XD
Citation:
bioRxiv. 2019;[preprint] doi:/10.1101/679167
Abstract:
Ybx1 has been demonstrated as a crucial gene in embryogenesis, reproduction as well as development in various vertebrates such...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huang C, Zhu B, Leng D, Ge W, Zhang XD. The lncRNAs Implicated in Redox Regulation in Ybx1 Deficient Zebrafish Larvae. bioRxiv. 2019;[preprint] doi:/10.1101/679167.

Cell and tissue morphology determine actin-dependent nuclear migration mechanisms in neuroepithelia

Authors:
Yanakieva I, Erzberger A, Matejčić M, Modes CD, Norden C
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/536698
Abstract:
Correct nuclear position is crucial for cellular function and tissue development. Depending on cell context however,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yanakieva I, Erzberger A, Matejčić M, Modes CD, Norden C. Cell and tissue morphology determine actin-dependent nuclear migration mechanisms in neuroepithelia. bioRxiv. 2019;[preprint] doi:10.1101/536698 .

Actomyosin regulation by Eph receptor signaling couples boundary cell formation to border sharpness

Authors:
Cayuso J, Xu Q, Addison M, Wilkinson DG
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/683631
Abstract:
The segregation of cells with distinct regional identity underlies formation of a sharp border, which in some tissues serves to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cayuso J, Xu Q, Addison M, Wilkinson DG. Actomyosin regulation by Eph receptor signaling couples boundary cell formation to border sharpness. bioRxiv. 2019;[preprint] doi:10.1101/683631 .

ΔN-Tp63 mediates Wnt/β-catenin-induced inhibition of differentiation in basal stem cells of mucociliary epithelia

Authors:
Haas M, Vázquez JLG, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/682534
Abstract:
Mucociliary epithelia provide a first line of defense against pathogens in the airways and the epidermis of vertebrate larvae....
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Haas M, Vázquez JLG, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P. ΔN-Tp63 mediates Wnt/β-catenin-induced inhibition of differentiation in basal stem cells of mucociliary epithelia. bioRxiv. 2019;[preprint] doi:10.1101/682534.

Dephosphorylation of HDAC4 by PP2A-Bδ unravels a new role for the HDAC4/MEF2 axis in myoblast fusion

Authors:
Veloso A, Martin M, Bruyr J, O’Grady T, Deroanne C, Mottet D, Twizere J-C, Cherrier T, Dequiedt F
Citation:
Cell Death & Dis. 2019;10(7):512. doi:10.1038/s41419-019-1743-6
Abstract:
Muscle formation is controlled by a number of key myogenic transcriptional regulators that govern stage-specific gene...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Veloso A, Martin M, Bruyr J, O’Grady T, Deroanne C, Mottet D, Twizere J-C, Cherrier T, Dequiedt F. Dephosphorylation of HDAC4 by PP2A-Bδ unravels a new role for the HDAC4/MEF2 axis in myoblast fusion. Cell Death & Dis. 2019;10(7):512. doi:10.1038/s41419-019-1743-6.

NIPBL: a new player in myeloid cell differentiation

Authors:
Mazzola M, Deflorian G, Pezzotta A, Ferrari L, Fazio G, Bresciani E, Saitta C, Ferrari L, Fumagalli M, Parma M, Marasca F, Bodega B, Riva P, Cotelli F, Biondi A, Marozzi A, Cazzaniga G, Pistocchi A
Citation:
Haematologica. 2019 Jul;104(7):1332-1341. doi: 10.3324/haematol.2018.200899. Epub 2019 Jan 10
Abstract:
The nucleophosmin 1 gene (NPM1) is the most frequently mutated gene in acute myeloid leukemia. Notably, NPM1 mutations are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mazzola M, Deflorian G, Pezzotta A, Ferrari L, Fazio G, Bresciani E, Saitta C, Ferrari L, Fumagalli M, Parma M, Marasca F, Bodega B, Riva P, Cotelli F, Biondi A, Marozzi A, Cazzaniga G, Pistocchi A. NIPBL: a new player in myeloid cell differentiation. Haematologica. 2019 Jul;104(7):1332-1341. doi: 10.3324/haematol.2018.200899. Epub 2019 Jan 10.

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