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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10101 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

The vertebrate-specific VENTX/NANOG gene empowers neural crest with ectomesenchyme potential

Authors:
Scerbo P, Monsoro-Burq AH
Citation:
Sci Adv. 2020;6(18):eaaz1469. doi:10.1126/sciadv.aaz1469
Abstract:
During Cambrian, unipotent progenitors located at the neural (plate) border (NB) of an Olfactoria chordate embryo acquired the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Scerbo P, Monsoro-Burq AH. The vertebrate-specific VENTX/NANOG gene empowers neural crest with ectomesenchyme potential. Sci Adv. 2020;6(18):eaaz1469. doi:10.1126/sciadv.aaz1469 .

miR-103/107 regulates left-right asymmetry in zebrafish by modulating Kupffer's vesicle development and ciliogenesis

Authors:
Heigwer J, Kutzner J, Haeussler M, Burkhalter MD, Draebing T, Juergensen L, Katus HA, Philipp M, Westhoff JH, Hassel D
Citation:
Biochem Biophys Res Commun. 2020 Apr 22. pii: S0006-291X(20)30792-0. doi: 10.1016/j.bbrc.2020.04.066. [Epub ahead of print]
Abstract:
In zebrafish, cilia movement within the Kupffer's vesicle (KV) generates a fluid flow responsible for accumulating nodal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Heigwer J, Kutzner J, Haeussler M, Burkhalter MD, Draebing T, Juergensen L, Katus HA, Philipp M, Westhoff JH, Hassel D. miR-103/107 regulates left-right asymmetry in zebrafish by modulating Kupffer's vesicle development and ciliogenesis. Biochem Biophys Res Commun. 2020 Apr 22. pii: S0006-291X(20)30792-0. doi: 10.1016/j.bbrc.2020.04.066. [Epub ahead of print].

Functional characterization of Neurofilament Light b splicing and misbalance in zebrafish

Authors:
Demy DL, Campanari M-L, Munoz-Ruiz R,Durham HD, Gentil B, Kabashi E
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.04.27.064063
Abstract:
Neurofilaments (NFs), a major cytoskeletal component of motor neurons, play a key role in their differentiation, establishment...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Demy DL, Campanari M-L, Munoz-Ruiz R,Durham HD, Gentil B, Kabashi E. Functional characterization of Neurofilament Light b splicing and misbalance in zebrafish. bioRxiv. 2020;[preprint] doi:10.1101/2020.04.27.064063.

Fgf-driven Tbx protein activities directly induce myf5 and myod to initiate zebrafish myogenesis

Authors:
Osborn DPS, Li K, Cutty SJ, Nelson AC, Wardle FC, Hinits Y, Hughes SM
Citation:
Development. 2020;147(8):[Epub] doi:10.1242/dev.184689
Abstract:
Skeletal muscle derives from dorsal mesoderm formed during vertebrate gastrulation. Fibroblast growth factor (Fgf) signalling...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Osborn DPS, Li K, Cutty SJ, Nelson AC, Wardle FC, Hinits Y, Hughes SM. Fgf-driven Tbx protein activities directly induce myf5 and myod to initiate zebrafish myogenesis. Development. 2020;147(8):[Epub] doi:10.1242/dev.184689.

Practical Synthesis of Quinoline-Protected Morpholino Oligomers for Light-Triggered Regulation of Gene Function

Authors:
Deodato D, Dore TM
Citation:
Molecules. 2020;25(9):2078. doi:10.3390/molecules25092078
Abstract:
Photoactivatable cyclic caged morpholino oligomers (ccMOs) represent a promising tool to selectively regulate gene expression...
Citation Extract:
Deodato D, Dore TM. Practical Synthesis of Quinoline-Protected Morpholino Oligomers for Light-Triggered Regulation of Gene Function. Molecules. 2020;25(9):2078. doi:10.3390/molecules25092078.

A homozygous MRPL24 mutation causes a complex movement disorder and affects the mitoribosome assembly

Authors:
Nottia MD, Marchese M, Verrigni D, Mutti C, Torraco A, Oliva R, Fernandez-Vizarra E, Morani F, Trani G, Rizza T, Ghezzi D, Ardissone A, Nesti C, Vasco G, Zeviani M, Minczuk M, Bertini E, Santorelli FM, Carrozzo R
Citation:
Neurobiol Dis. 2020 Apr 25:104880. doi: 10.1016/j.nbd.2020.104880. [Epub ahead of print]
Abstract:
Mitochondrial ribosomal protein large 24 (MRPL24) is 1 of the 82 protein components of mitochondrial ribosomes, playing an...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nottia MD, Marchese M, Verrigni D, Mutti C, Torraco A, Oliva R, Fernandez-Vizarra E, Morani F, Trani G, Rizza T, Ghezzi D, Ardissone A, Nesti C, Vasco G, Zeviani M, Minczuk M, Bertini E, Santorelli FM, Carrozzo R. A homozygous MRPL24 mutation causes a complex movement disorder and affects the mitoribosome assembly. Neurobiol Dis. 2020 Apr 25:104880. doi: 10.1016/j.nbd.2020.104880. [Epub ahead of print].

Mis12 controls cyclin B1 stabilization via Cdc14B-mediated APC/CCdh1 regulation during meiotic G2/M transition in mouse oocytes

Authors:
Bai G-Y, Choe MH, Kim J-S, Oh JS
Citation:
Development. 2020;147(8):[Epub ahead of print] doi:10.1242/dev.185322
Abstract:
Mammalian oocytes are arrested at G2/prophase of the first meiosis. After a hormone surge, oocytes resume meiosis, undergoing...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Bai G-Y, Choe MH, Kim J-S, Oh JS. Mis12 controls cyclin B1 stabilization via Cdc14B-mediated APC/CCdh1 regulation during meiotic G2/M transition in mouse oocytes. Development. 2020;147(8):[Epub ahead of print] doi:10.1242/dev.185322.

Role of kif2c, A Gene Related to ALL Relapse, in Embryonic Hematopoiesis in Zebrafish

Authors:
Oh C-K, Kang JW, Lee Y, Myung K, Ha M, Kang J, Kwon EJ, Kim Y, Oh S-O, Heo HJ, Kim S, Kim YH
Citation:
Int J Molec Sci. 2020;21(9):3127. doi:10.3390/ijms21093127
Abstract:
Relapse of acute lymphoblastic leukemia (ALL) is dangerous and it worsens the prognosis of patients; however, prognostic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Oh C-K, Kang JW, Lee Y, Myung K, Ha M, Kang J, Kwon EJ, Kim Y, Oh S-O, Heo HJ, Kim S, Kim YH. Role of kif2c, A Gene Related to ALL Relapse, in Embryonic Hematopoiesis in Zebrafish. Int J Molec Sci. 2020;21(9):3127. doi:10.3390/ijms21093127.

Nodal and Planar Cell Polarity signaling cooperate to regulate zebrafish convergence and extension gastrulation movements

Authors:
Williams MLK, Solnica-Krezel L
Citation:
Elife. 2020 Apr 22;9. pii: e54445. doi: 10.7554/eLife.54445. [Epub ahead of print]
Abstract:
During vertebrate gastrulation, convergence & extension (C&E) of the primary anteroposterior (AP) embryonic axis is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Williams MLK, Solnica-Krezel L. Nodal and Planar Cell Polarity signaling cooperate to regulate zebrafish convergence and extension gastrulation movements. Elife. 2020 Apr 22;9. pii: e54445. doi: 10.7554/eLife.54445. [Epub ahead of print].

Deficiency in the autophagy modulator Dram1 exacerbates pyroptotic cell death of Mycobacteria-infected macrophages

Authors:
Zhang R, Varela M, Forn-Cuní G, Torraca V, Michiel van der Vaart M, Meijer AH
Citation:
Cell Death Dis. 2020;11:277 doi:10.1038/s41419-020-2477-1
Abstract:
DNA damage regulated autophagy modulator 1 (DRAM1) is a stress-inducible regulator of autophagy and cell death. DRAM1 has been...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang R, Varela M, Forn-Cuní G, Torraca V, Michiel van der Vaart M, Meijer AH. Deficiency in the autophagy modulator Dram1 exacerbates pyroptotic cell death of Mycobacteria-infected macrophages. Cell Death Dis. 2020;11:277 doi:10.1038/s41419-020-2477-1.

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