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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9450 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Prostaglandin signaling regulates renal multiciliated cell specification and maturation

Authors:
Marra AN, Adeeb BD, Chambers BE, Drummond BE, Ulrich M, Addiego A, Springer M, Poureetezadi SJ, Chambers JM, Ronshaugen M, Wingert RA
Citation:
Proc Natl Acad Sci U S A. 2019 Apr 4. pii: 201813492. doi: 10.1073/pnas.1813492116. [Epub ahead of print]
Abstract:
Multiciliated cells (MCCs) are specialized epithelia with apical bundles of motile cilia that direct fluid flow. MCC...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marra AN, Adeeb BD, Chambers BE, Drummond BE, Ulrich M, Addiego A, Springer M, Poureetezadi SJ, Chambers JM, Ronshaugen M, Wingert RA. Prostaglandin signaling regulates renal multiciliated cell specification and maturation. Proc Natl Acad Sci U S A. 2019 Apr 4. pii: 201813492. doi: 10.1073/pnas.1813492116. [Epub ahead of print].

Neural crest streaming as an emergent property of tissue interactions during morphogenesis

Authors:
Szabó A, Theveneau E, Turan M, Mayor R
Citation:
PLoS Comput Biol. 2019;15(4):e1007002. doi:10.1371/journal.pcbi.1007002
Abstract:
A fundamental question in embryo morphogenesis is how a complex pattern is established in seemingly uniform tissues. During...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Szabó A, Theveneau E, Turan M, Mayor R. Neural crest streaming as an emergent property of tissue interactions during morphogenesis. PLoS Comput Biol. 2019;15(4):e1007002. doi:10.1371/journal.pcbi.1007002.

Primary cilia regulate hematopoietic stem and progenitor cell specification through Notch signaling in zebrafish

Authors:
Liu Z, Tu H, Kang Y, Xue Y, Ma D, Zhao C, Li H, Wang L, Liu F
Citation:
Nat Comm. 2019;10(1):1839. doi:10.1038/s41467-019-09403-7
Abstract:
Hematopoietic stem and progenitor cells (HSPCs) are capable of producing all mature blood lineages, as well as maintaining the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu Z, Tu H, Kang Y, Xue Y, Ma D, Zhao C, Li H, Wang L, Liu F. Primary cilia regulate hematopoietic stem and progenitor cell specification through Notch signaling in zebrafish. Nat Comm. 2019;10(1):1839. doi:10.1038/s41467-019-09403-7.

Iroquois transcription factor irx2a is required for multiciliated and transporter cell fate decisions during zebrafish pronephros development

Authors:
Marra AN, Cheng CN, Adeeb B, Addiego A, Wesselman HM, Chambers BE, Chambers JM, Wingert RA
Citation:
Sci Rep. 2019;9(1):6454. doi:10.1038/s41598-019-42943-y
Abstract:
The genetic regulation of nephron patterning during kidney organogenesis remains poorly understood. Nephron tubules in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marra AN, Cheng CN, Adeeb B, Addiego A, Wesselman HM, Chambers BE, Chambers JM, Wingert RA. Iroquois transcription factor irx2a is required for multiciliated and transporter cell fate decisions during zebrafish pronephros development. Sci Rep. 2019;9(1):6454. doi:10.1038/s41598-019-42943-y.

Metabolic regulation by the PGC-1α and PGC-1β coactivators in larval zebrafish (Danio rerio)

Authors:
Northam C, LeMoine CMR
Citation:
Comp Biochem Physiol A Mol Integr Physiol. 2019 Apr 17. pii: S1095-6433(18)30349-0. doi: 10.1016/j.cbpa.2019.04.011. [Epub ahead of print]
Abstract:
The peroxisome proliferator activated receptor γ coactivator-1 (PGC-1) family is composed of three coactivators whose role in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Northam C, LeMoine CMR. Metabolic regulation by the PGC-1α and PGC-1β coactivators in larval zebrafish (Danio rerio). Comp Biochem Physiol A Mol Integr Physiol. 2019 Apr 17. pii: S1095-6433(18)30349-0. doi: 10.1016/j.cbpa.2019.04.011. [Epub ahead of print].

Mutations in the zebrafish hmgcs1 gene reveal a novel function for isoprenoids during red blood cell development

Authors:
Hernandez JA, Castro VL, Reyes-Nava N, Montes LP, Quintana AM
Citation:
Blood Adv. 2019 Apr 23;3(8):1244-1254. doi: 10.1182/bloodadvances.2018024539
Abstract:
Erythropoiesis is the process by which new red blood cells (RBCs) are formed and defects in this process can lead to anemia or...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hernandez JA, Castro VL, Reyes-Nava N, Montes LP, Quintana AM. Mutations in the zebrafish hmgcs1 gene reveal a novel function for isoprenoids during red blood cell development. Blood Adv. 2019 Apr 23;3(8):1244-1254. doi: 10.1182/bloodadvances.2018024539.

The Glycogen Synthase Kinase-3β Inhibitor LSN 2105786 Promotes Zebrafish Fin Regeneration

Authors:
Sarmah S, Curtis C, Mahin J, Farrell M, Engler TA, Sanchez-Felix MN, Sato M, Ma YL, Chu S, Marrs JA
Citation:
Biomedicines. 2019;7(2):30. doi:10.3390/biomedicines7020030
Abstract:
The Wnt pathway has been shown to regulate bone homeostasis and to influence some bone disease states. We utilized a zebrafish...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sarmah S, Curtis C, Mahin J, Farrell M, Engler TA, Sanchez-Felix MN, Sato M, Ma YL, Chu S, Marrs JA. The Glycogen Synthase Kinase-3β Inhibitor LSN 2105786 Promotes Zebrafish Fin Regeneration. Biomedicines. 2019;7(2):30. doi:10.3390/biomedicines7020030.

Regardless of the deposition pathway, aminoacid 31 in histone variant H3 is essential at gastrulation in Xenopus

Authors:
Sitbon D, Boyarchuk E, Almouzni G
Citation:
bioRxiv.2019;[preprint] doi:10.1101/612515
Abstract:
The closely related replicative H3 and non-replicative H3.3 variants show specific requirement during development in...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Sitbon D, Boyarchuk E, Almouzni G. Regardless of the deposition pathway, aminoacid 31 in histone variant H3 is essential at gastrulation in Xenopus. bioRxiv.2019;[preprint] doi:10.1101/612515.

Coupling metastasis to pH sensing G Protein-coupled receptor-68 through first in class inhibitor identified in an in vivo chemical genetic screen

Authors:
Williams CH, Thayer T, Wells Q, Wani M, Keyser B, Hong CC
Citation:
bioRxiv.2019;[preprint] doi:10.1101/612549
Abstract:
Acidic milieu is a hallmark of glycolytic metabolism which occurs in cancerous cells. The effect of the acidic environment on...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Williams CH, Thayer T, Wells Q, Wani M, Keyser B, Hong CC. Coupling metastasis to pH sensing G Protein-coupled receptor-68 through first in class inhibitor identified in an in vivo chemical genetic screen. bioRxiv.2019;[preprint] doi:10.1101/612549.

QDPR homologues in Danio rerio regulate melanin synthesis, early gliogenesis, and glutamine homeostasis

Authors:
Breuer M, Guglielmi L, Zielonka M, Hemberger V, Kölker S, Okun JG, Hoffmann GF, Carl M, Sauer SW, Opladen T
Citation:
PLoS ONE. 2019;14(4):e0215162. doi:10.1371/journal.pone.0215162
Abstract:
Dihydropteridine reductase (QDPR) catalyzes the recycling of tetrahydrobiopterin (BH4), a cofactor in dopamine, serotonin, and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Breuer M, Guglielmi L, Zielonka M, Hemberger V, Kölker S, Okun JG, Hoffmann GF, Carl M, Sauer SW, Opladen T. QDPR homologues in Danio rerio regulate melanin synthesis, early gliogenesis, and glutamine homeostasis. PLoS ONE. 2019;14(4):e0215162. doi:10.1371/journal.pone.0215162.

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