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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
An anti-sense oligonucleotide efficiently suppresses splicing of an alternative exon in vascular smooth muscle in vivo
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Citation:
Am J Physiol Heart Circ Physiol. 2024 Jan 26. doi: 10.1152/ajpheart.00745.2023. Online ahead of print Epub:
Yes Abstract:
Targeting alternative exons for therapeutic gain has been achieved in a few instances and potentially could be applied more... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Damacena de Angelis C, Meddeb M, Chen N, Fisher SA. An anti-sense oligonucleotide efficiently suppresses splicing of an alternative exon in vascular smooth muscle in vivo. Am J Physiol Heart Circ Physiol. 2024 Jan 26. doi: 10.1152/ajpheart.00745.2023. Online ahead of print. |
Moderate Elevation of Homocysteine Induces Endothelial Dysfunction through Adaptive UPR Activation and Metabolic Rewiring
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Citation:
Cells. 2024;13:214. doi:10.3390/cells13030214 Epub:
Not Epub Abstract:
Elevation of the intermediate amino acid metabolite Homocysteine (Hcy) causes Hyperhomocysteinemia (HHcy), a metabolic disorder... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chatterje B, Fatima F, Seth S, Sinha Roy S. Moderate Elevation of Homocysteine Induces Endothelial Dysfunction through Adaptive UPR Activation and Metabolic Rewiring. Cells. 2024;13:214. doi:10.3390/cells13030214. |
TUBA4A downregulation as observed in ALS post-mortem motor cortex causes ALS-related abnormalities in zebrafish
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Citation:
Front Cell Neurosci. 2024;18:[Epub] doi:10.3389/fncel.2024.1340240 Epub:
Yes Abstract:
Disease-associated variants of TUBA4A (alpha-tubulin 4A) have recently been identified in familial ALS. Interestingly, a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Van Schoor E, Strubbe D, Braems E, Weishaupt J, Ludolph A, Van Damme P, Thal DR, Bercier V, Van Den Bosch L. TUBA4A downregulation as observed in ALS post-mortem motor cortex causes ALS-related abnormalities in zebrafish. Front Cell Neurosci. 2024;18:[Epub] doi:10.3389/fncel.2024.1340240. |
Deficiency of copper responsive gene stmn4 induces retinal developmental defects
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Citation:
Cell Biol Toxicol. 2024 Jan 22;40(1):2. doi: 10.1007/s10565-024-09847-8 Epub:
Not Epub Abstract:
As part of the central nervous system (CNS), the retina senses light and also conducts and processes visual impulses. The... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jing Y, Luo Y, Li L, Liu M, Liu JX. Deficiency of copper responsive gene stmn4 induces retinal developmental defects. Cell Biol Toxicol. 2024 Jan 22;40(1):2. doi: 10.1007/s10565-024-09847-8. |
The Effect of Morpholino Oligonucleotides to Gene Anxa2a on the Embryonic Development of Danio rerio
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Citation:
Mol Gen Microbiol Virol. 2024;38:143-9. doi:10.3103/S0891416823030059 Epub:
Not Epub Abstract:
The Annexin 2 protein (ANXA2) encoded by the ANXA2 gene performs a number of biological functions that are primarily related to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Partevian SA, Safina DR, Rudenok MM, Rybolovlev IN, Semenova EI, Shadrina MI, Slominsky PA, Kostrov SV, Alieva AKh. The Effect of Morpholino Oligonucleotides to Gene Anxa2a on the Embryonic Development of Danio rerio. Mol Gen Microbiol Virol. 2024;38:143-9. doi:10.3103/S0891416823030059. |
Epileptic phenotypes in slc13a5 loss-of-function zebrafish are rescued by blocking NMDA receptor signaling
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Citation:
bioRxiv. 2024;[preprint] doi:10.1101/2024.01.15.575806 Epub:
Not Epub Abstract:
SLC13A5 encodes a citrate transporter highly expressed in the brain important for regulating intra- and extracellular citrate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dogra D, Phan VA, Gavrilovici C, DiMarzo N, Ibhazehiebo K, Kurrasch DM. Epileptic phenotypes in slc13a5 loss-of-function zebrafish are rescued by blocking NMDA receptor signaling. bioRxiv. 2024;[preprint] doi:10.1101/2024.01.15.575806. |
Endogenous biosynthesis of docosahexaenoic acid (DHA) regulates fish oocyte maturation by promoting pregnenolone production
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Citation:
Zool Res. 2024 Jan 18;45(1):176-188. doi: 10.24272/j.issn.2095-8137.2023.032 Epub:
Not Epub Abstract:
Omega-3 polyunsaturated fatty acids (n-3 PUFAs), particularly docosahexaenoic acid (22:6n-3, DHA), play crucial roles in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li Y, Li X, Ye D, Zhang R, Liu C, He M, Wang H, Hu W, Sun Y. Endogenous biosynthesis of docosahexaenoic acid (DHA) regulates fish oocyte maturation by promoting pregnenolone production. Zool Res. 2024 Jan 18;45(1):176-188. doi: 10.24272/j.issn.2095-8137.2023.032. |
Ciliary length regulation by intraflagellar transport in zebrafish
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Citation:
bioRxiv. 2024;[preprint] doi:10.1101/2024.01.16.575975 Epub:
Not Epub Abstract:
How cells regulate the size of their organelles remains a fundamental question in cell biology. Cilia, with their simple... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun Y, Chen Z, Jin M, Xie H, Zhao C. Ciliary length regulation by intraflagellar transport in zebrafish. bioRxiv. 2024;[preprint] doi:10.1101/2024.01.16.575975. |
Dyrk1a is required for craniofacial development in Xenopus laevis
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Citation:
bioRxiv. 2024;[preprint] doi:10.1101/2024.01.13.575394 Epub:
Not Epub Abstract:
Loss of function mutations in the dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) gene are associated... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Johnson HK, Wahl SE, Sesay F, Litovchick L, Dickinson AJG. Dyrk1a is required for craniofacial development in Xenopus laevis. bioRxiv. 2024;[preprint] doi:10.1101/2024.01.13.575394. |
Characterizing CSNK2A1 Mutant-Induced Morphological Phenotypes in Zebrafish (Danio rerio): Insights into Okur-Chung Neurodevelopmental Syndrome (OCNDS)
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Citation:
bioRxiv. 2024;[preprint] doi:10.1101/2024.01.09.574075 Epub:
Not Epub Abstract:
Okur-Chung Neurodevelopmental Syndrome (OCNDS) is a rare, autosomal dominant disorder caused by heterozygous pathogenic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hassett K, Potu SS, Sankaramoorthy A, Kaneshamoorthy S, Leka K, Huentelman MJ, Narayanan V, Rangasamy S. Characterizing CSNK2A1 Mutant-Induced Morphological Phenotypes in Zebrafish (Danio rerio): Insights into Okur-Chung Neurodevelopmental Syndrome (OCNDS). bioRxiv. 2024;[preprint] doi:10.1101/2024.01.09.574075. |