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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9876 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Ascidian caveolin induces membrane curvature and protects tissue integrity and morphology during embryogenesis

Authors:
Bhattachan P, Rae J, Yu H, Jung W, Wei J, Parton RG, Dong B
Citation:
FASEB J. 2020 Jan;34(1):1345-1361. doi: 10.1096/fj.201901281R. Epub 2019 Nov 30
Abstract:
Cell morphology and tissue integrity are essential for embryogenesis. Caveolins are membrane proteins that induce the formation...
Delivery Method:
microinjection
Organism or Cell Type:
Ciona sp.
Citation Extract:
Bhattachan P, Rae J, Yu H, Jung W, Wei J, Parton RG, Dong B. Ascidian caveolin induces membrane curvature and protects tissue integrity and morphology during embryogenesis. FASEB J. 2020 Jan;34(1):1345-1361. doi: 10.1096/fj.201901281R. Epub 2019 Nov 30.

METTL3-mediated m6A is required for murine oocyte maturation and maternal-to-zygotic transition

Authors:
Sui X, Hu Y, Ren C, Cao Q, Zhou S, Cao Y, Li M, Shu W, Huo R
Citation:
Cell Cycle. 2020 Jan 9:1-14. doi: 10.1080/15384101.2019.1711324. [Epub ahead of print]
Abstract:
N6-methyladenosine (m6A) is the most prevalent epigenetic modification of messenger RNA (mRNA) in higher eukaryotes; this...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Sui X, Hu Y, Ren C, Cao Q, Zhou S, Cao Y, Li M, Shu W, Huo R. METTL3-mediated m6A is required for murine oocyte maturation and maternal-to-zygotic transition. Cell Cycle. 2020 Jan 9:1-14. doi: 10.1080/15384101.2019.1711324. [Epub ahead of print].

ESCRT subunit CHMP4B localizes to primary cilia and is required for the structural integrity of the ciliary membrane

Authors:
Jung E, Choi TI, Lee JE, Kim CH, Kim J
Citation:
FASEB J. 2020 Jan;34(1):1331-1344. doi: 10.1096/fj.201901778R. Epub 2019 Nov 29
Abstract:
Proteins specialized in the detection, generation, or stabilization of membrane curvature play important roles in establishing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jung E, Choi TI, Lee JE, Kim CH, Kim J. ESCRT subunit CHMP4B localizes to primary cilia and is required for the structural integrity of the ciliary membrane. FASEB J. 2020 Jan;34(1):1331-1344. doi: 10.1096/fj.201901778R. Epub 2019 Nov 29.

Programmed cell death along the midline axis patterns ipsilaterality in gastrulation

Authors:
Maya-Ramos L, Mikawa T
Citation:
Science. 2020;367(6474):197-200. doi:10.1126/science.aaw2731
Abstract:
Bilateral symmetry is the predominant body plan in the animal kingdom. Cells on the left and right sides remain...
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Maya-Ramos L, Mikawa T. Programmed cell death along the midline axis patterns ipsilaterality in gastrulation. Science. 2020;367(6474):197-200. doi:10.1126/science.aaw2731 .

NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis

Authors:
Tournière O, Dolan D, Richards GS, Sunagar K, Columbus-Shenkar YY, Moran Y, Rentzsch F
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.01.08.898437
Abstract:
Terminal selectors are transcription factors that control the morphological, physiological and molecular features that...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Tournière O, Dolan D, Richards GS, Sunagar K, Columbus-Shenkar YY, Moran Y, Rentzsch F. NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis. bioRxiv. 2020;[preprint] doi:10.1101/2020.01.08.898437.

Dual role of Jam3b in early hematopoietic and vascular development

Authors:
Kobayashi I, Kobayashi-Sun J, Hirakawa Y, Ouchi M, Yasuda K, Kamei H, Fukuhara S, Yamaguchi M
Citation:
Development. 2020;147(1):dev181040. doi:10.1242/dev.181040
Abstract:
In order to efficiently derive hematopoietic stem cells (HSCs) from pluripotent precursors, it is crucial to understand how...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kobayashi I, Kobayashi-Sun J, Hirakawa Y, Ouchi M, Yasuda K, Kamei H, Fukuhara S, Yamaguchi M. Dual role of Jam3b in early hematopoietic and vascular development. Development. 2020;147(1):dev181040. doi:10.1242/dev.181040 .

Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21

Authors:
Hackett EE, Charles-Messance H, O’Leary SM, Gleeson LE, Muñoz-Wolf N, Case S, Wedderburn A, Johnston DGW, Williams MA, Smyth A, Ouimet M, Moore KJ, Lavelle EC, Corr SC, Gordon SV, Keane J, Sheedy FJ
Citation:
Cell Rep. 2020;30(1):124-36.e4. doi:10.1016/j.celrep.2019.12.015
Abstract:
Increased glycolytic metabolism recently emerged as an essential process driving host defense against Mycobacterium...
Delivery Method:
Lipofectamine 2000
Organism or Cell Type:
cell culture: bone-marrow-derived macrophages (BMDMs)
Citation Extract:
Hackett EE, Charles-Messance H, O’Leary SM, Gleeson LE, Muñoz-Wolf N, Case S, Wedderburn A, Johnston DGW, Williams MA, Smyth A, Ouimet M, Moore KJ, Lavelle EC, Corr SC, Gordon SV, Keane J, Sheedy FJ. Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21. Cell Rep. 2020;30(1):124-36.e4. doi:10.1016/j.celrep.2019.12.015.

U1 snRNP regulates cancer cell migration and invasion in vitro

Authors:
Oh J, Venters CC, Di C, Pinto AM, Wan L, Younis I, Cai Z, Arai C, So BR, Duan J, Dreyfuss G
Citation:
Nat Commun. 2020;11:1. doi:10.1038/s41467-019-13993-7
Abstract:
Stimulated cells and cancer cells have widespread shortening of mRNA 3’-untranslated regions (3’UTRs) and switches to shorter...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: HeLa, A549, MCF-7 & MDA-MB-231
Citation Extract:
Oh J, Venters CC, Di C, Pinto AM, Wan L, Younis I, Cai Z, Arai C, So BR, Duan J, Dreyfuss G. U1 snRNP regulates cancer cell migration and invasion in vitro. Nat Commun. 2020;11:1. doi:10.1038/s41467-019-13993-7.

Glycogen storage in a zebrafish Pompe disease model is reduced by 3-BrPA treatment

Authors:
Bragato C, Carra S, Blasevich F, Salerno F, Brix A, Bassi A, Beltrame M, Cotelli F, Maggi L, Mantegazza R, Mora M
Citation:
Biochim Biophys Acta Mol Basis Dis. 2020;[epub ahead of print] doi:10.1016/j.bbadis.2020.165662
Abstract:
Pompe disease (PD) is an autosomal recessive muscular disorder caused by deficiency of the glycogen hydrolytic enzyme acid α-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bragato C, Carra S, Blasevich F, Salerno F, Brix A, Bassi A, Beltrame M, Cotelli F, Maggi L, Mantegazza R, Mora M. Glycogen storage in a zebrafish Pompe disease model is reduced by 3-BrPA treatment. Biochim Biophys Acta Mol Basis Dis. 2020;[epub ahead of print] doi:10.1016/j.bbadis.2020.165662.

Disrupted ER membrane protein complex-mediated topogenesis drives congenital neural crest defects

Authors:
Marquez J, Criscione J, Charney RM, Prasad MS, Hwang WY, Mis EK, García-Castro MI, Khokha MK
Citation:
J Clin Invest. 2020 Jan 6. pii: 129308. doi: 10.1172/JCI129308. [Epub ahead of print]
Abstract:
Multipass membrane proteins have a myriad of functions, including transduction of cell-cell signals, ion transport, and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Marquez J, Criscione J, Charney RM, Prasad MS, Hwang WY, Mis EK, García-Castro MI, Khokha MK. Disrupted ER membrane protein complex-mediated topogenesis drives congenital neural crest defects. J Clin Invest. 2020 Jan 6. pii: 129308. doi: 10.1172/JCI129308. [Epub ahead of print].

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