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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
There are 12221 scientific papers returned from the database with the search filters currently being used below.
Smurf1 regulates neural patterning and folding in Xenopus embryos by antagonizing the BMP/Smad1 pathway
Citation:
Dev Biol. 2006 Nov 15;299(2):398-410. Epub 2006 Aug 10. Epub:
Not Epub Abstract:
The ubiquitin ligase Smurf1 can target a handful of signaling proteins for ubiquitin-mediated proteasomal destruction or... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Alexandrova EM, Thomsen GH. Smurf1 regulates neural patterning and folding in Xenopus embryos by antagonizing the BMP/Smad1 pathway. Dev Biol. 2006 Nov 15;299(2):398-410. Epub 2006 Aug 10.. |
Sox10 regulates the development of neural crest-derived melanocytes in Xenopus.
Citation:
Dev Biol. 2003 Jul 1;259(1):19-33 Epub:
Not Epub Abstract:
The transcription factors of the Sox family play important roles in diverse developmental processes. A number of genetic... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Aoki Y, Saint-Germain N, Gyda M, Magner-Fink E, Lee YH, Credidio C, Saint-Jeannet JP. Sox10 regulates the development of neural crest-derived melanocytes in Xenopus.. Dev Biol. 2003 Jul 1;259(1):19-33. |
Sox17 and chordin are required for formation of Kupffer's vesicle and left-right asymmetry determination in zebrafish
Citation:
Dev Dyn. 2010 Oct 5. [Epub ahead of print] Epub:
Not Epub Abstract:
Kupffer's vesicle (KV), a ciliated fluid-filled sphere in the zebrafish embryo with a critical role in laterality... Organism or Cell Type:
zebrafish Citation Extract: Aamar E, Dawid IB. Sox17 and chordin are required for formation of Kupffer's vesicle and left-right asymmetry determination in zebrafish. Dev Dyn. 2010 Oct 5. [Epub ahead of print]. |
SoxB1 downregulation in vegetal lineages of sea urchin embryos is achieved by both transcriptional repression and selective protein turnover
Citation:
Development. 2005 Mar;132(5):999-1008. Epub 2005 Feb 2 Epub:
Not Epub Abstract:
Patterning of cell fates along the sea urchin animal-vegetal embryonic axis requires the opposing functions of nuclear beta-... Delivery Method:
Microinjection Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus Citation Extract: Angerer LM, Newman LA, Angerer RC. SoxB1 downregulation in vegetal lineages of sea urchin embryos is achieved by both transcriptional repression and selective protein turnover. Development. 2005 Mar;132(5):999-1008. Epub 2005 Feb 2. |
Spdeadringer, a sea urchin embryo gene required separately in skeletogenic and oral ectoderm gene regulatory networks
Citation:
Dev Biol. 2003 Sep 1;261(1):55-81. Epub:
Not Epub Abstract:
The Spdeadringer (Spdri) gene encodes an ARID-class transcription factor not previously known in sea urchin embryos. We show... Delivery Method:
Microinjection Organism or Cell Type:
Sea urchins Citation Extract: Amore G, Yavrouian RG, Peterson KJ, Ransick A, McClay DR, Davidson EH. Spdeadringer, a sea urchin embryo gene required separately in skeletogenic and oral ectoderm gene regulatory networks. Dev Biol. 2003 Sep 1;261(1):55-81.. |
Splice Redirection as a Convenient Assay to Monitor CPP-ON Efficiency and Mechanism
Citation:
Methods Mol Biol. 2011;683:307-20 Epub:
Not Epub Abstract:
Several strategies based on synthetic oligonucleotides (ON) have been proposed to control gene expression. As for most... Delivery Method:
peptide-coupled Citation Extract: Abes R, Arzumanov AA, Saleh AF, Said Hassane F, Gait MJ, Lebleu B. Splice Redirection as a Convenient Assay to Monitor CPP-ON Efficiency and Mechanism. Methods Mol Biol. 2011;683:307-20. |
Swelling-activated Ca2+ entry via TRPV4 channel is defective in cystic fibrosis airway epithelia
Citation:
J Biol Chem. 2004 Dec 24;279(52):54062-8. Epub 2004 Oct 15 Epub:
Not Epub Abstract:
The vertebrate transient receptor potential cationic channel TRPV4 has been proposed as an osmo- and mechanosensor channel.... Delivery Method:
transfection Organism or Cell Type:
cell culture: CFT1 cells Citation Extract: Arniges M, Vazquez E, Fernandez-Fernandez JM, Valverde MA. Swelling-activated Ca2+ entry via TRPV4 channel is defective in cystic fibrosis airway epithelia. J Biol Chem. 2004 Dec 24;279(52):54062-8. Epub 2004 Oct 15. |
Synthesis and Properties of Nucleic Acid Methylene Carboxamide Mimics Derived from Morpholine Nucleosides
Citation:
Russian Journal of Bioorganic Chemistry, 2012, Vol. 38, No. 4, pp. 400–411. Epub:
Not Epub Abstract:
Uracyl and adenine containing oligomers derived from carboxymethyl derivatives of morpholine nucleoside analogues (MorGly) were... Citation Extract: Abramova TV, Kassakin MF, Tarasenko YV, Lomzov AA, Koval VV, Pyshnyi DV, Silnikov VN. Synthesis and Properties of Nucleic Acid Methylene Carboxamide Mimics Derived from Morpholine Nucleosides. Russian Journal of Bioorganic Chemistry, 2012, Vol. 38, No. 4, pp. 400–411.. |
Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology
Citation:
Nat Med. 2006 Feb;12(2):175-7. Epub 2006 Jan 29 Epub:
Not Epub Abstract:
For the majority of Duchenne muscular dystrophy (DMD) mutations, antisense oligonucleotide (AON)-mediated exon skipping has the... Delivery Method:
Injection Organism or Cell Type:
mice Citation Extract: Alter J, Lou F, Rabinowitz A, Yin H, Rosenfeld J, Wilton SD, Partridge TA, Lu QL. Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology. Nat Med. 2006 Feb;12(2):175-7. Epub 2006 Jan 29. |
T-box gene tbx5 is essential for formation of the pectoral limb bud.
Citation:
Nature 2002 Jun 13;417(6890):754-8 Epub:
Not Epub Abstract:
The T-box genes Tbx4 and Tbx5 have been shown to have key functions in the specification of the identity of the vertebrate... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Ahn DG, Kourakis MJ, Rohde LA, Silver LM, Ho RK. T-box gene tbx5 is essential for formation of the pectoral limb bud.. Nature 2002 Jun 13;417(6890):754-8. |