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Morpholino Publication Database
      This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12511 scientific papers returned from the database with the search filters currently being used below.
    
  
      There are 12511 scientific papers returned from the database with the search filters currently being used below.
Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism
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       Citation:        
  Nat Cell Biol 2002 Sep;4(9):674-680       Epub:        
  Not Epub       Abstract:        
  Mitochondrial aconitase is sensitive to oxidative inactivation and can aggregate and accumulate in many age-related disorders....       Delivery Method:        
  Special Delivery       Organism or Cell Type:        
  cell culture: human fibroblasts WI-38 VA-13       Citation Extract:              Bota DA, Davies KJ. Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism. Nat Cell Biol 2002 Sep;4(9):674-680.    | 
          
Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane
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       Citation:        
  Blood. 2011 Oct 6;118(14):3979-89. Epub 2011 Aug 11       Epub:        
  Not Epub       Abstract:        
  Sprouting angiogenesis is associated with extensive extracellular matrix (ECM) remodeling. The molecular mechanisms involved in...       Delivery Method:        
  Microinjection       Organism or Cell Type:        
  zebrafish       Citation Extract:              Bignon M, Pichol-Thievend C, Hardouin J, Malbouyres M, Bréchot N, Nasciutti L, Barret A, Teillon J, Guillon E, Etienne E, Caron M, Joubert-Caron R, Monnot C, Ruggiero F, Muller L, Germain S. Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane. Blood. 2011 Oct 6;118(14):3979-89. Epub 2011 Aug 11.    | 
          
meis1 regulates cyclin D1 and c-myc expression, and controls the proliferation of the multipotent cells in the early developing zebrafish eye
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       Citation:        
  Development. 2008 Mar;135(5):799-803. Epub 2008 Jan 23.       Epub:        
  Not Epub       Abstract:        
  During eye development, retinal progenitors are drawn from a multipotent, proliferative cell population. In Drosophila the...       Delivery Method:        
  Microinjection       Organism or Cell Type:        
  zebrafish       Citation Extract:              Bessa J, Tavares MJ, Santos J, Kikuta H, Laplante M, Becker TS, Gómez-Skarmeta JL, Casares F. meis1 regulates cyclin D1 and c-myc expression, and controls the proliferation of the multipotent cells in the early developing zebrafish eye. Development. 2008 Mar;135(5):799-803. Epub 2008 Jan 23..    | 
          
MicroRNA-9 Reveals Regional Diversity of Neural Progenitors along the Anterior-Posterior Axis
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       Citation:        
  Dev Cell. 2011 Jan 18;20(1):19-32       Epub:        
  Not Epub       Abstract:        
  Neural progenitors self-renew and generate neurons throughout the central nervous system. Here, we uncover an unexpected...       Delivery Method:        
  Microinjection       Organism or Cell Type:        
  Xenopus tropicalis       Citation Extract:              Bonev B, Pisco A, Papalopulu N. MicroRNA-9 Reveals Regional Diversity of Neural Progenitors along the Anterior-Posterior Axis. Dev Cell. 2011 Jan 18;20(1):19-32.    | 
          
Midline crossing is not required for subsequent pathfinding decisions in commissural neurons
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       Citation:        
  Neural Dev. 2012;7:18 doi:10.1186/1749-8104-7-18       Epub:        
  Not Epub       Abstract:        
  Growth cone navigation across the vertebrate midline is critical in the establishment of nervous system connectivity. While...       Delivery Method:        
  Microinjection       Organism or Cell Type:        
  zebrafish       Citation Extract:              Bonner J, Letko M, Nikolaus OB, Krug mL, Cooper A, Chadwick B, Conklin P, Lim A, Chien CB, Dorsky RI. Midline crossing is not required for subsequent pathfinding decisions in commissural neurons. Neural Dev. 2012;7:18 doi:10.1186/1749-8104-7-18.    | 
          
miR-27b controls venous specification and tip cell fate
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       Citation:        
  Blood. 2012 Mar 15;119(11):2679-87. doi: 10.1182/blood-2011-07-370635. Epub 2011 Dec 29       Epub:        
  Not Epub       Abstract:        
  We discovered that miR-27b controls 2 critical vascular functions: it turns the angiogenic switch on by promoting endothelial...       Delivery Method:        
  Microinjection       Organism or Cell Type:        
  zebrafish       Citation Extract:              Biyashev D, Veliceasa D, Topczewski J, Topczewska JM, Mizgirev I, Vinokour E, Reddi AL, Licht JD, Revskoy SY, Volpert OV. miR-27b controls venous specification and tip cell fate. Blood. 2012 Mar 15;119(11):2679-87. doi: 10.1182/blood-2011-07-370635. Epub 2011 Dec 29.    | 
          
Molecular cloning, gene expression in albino mutants and gene knockdown studies of tyrosinase mRNA in rainbow trout
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       Citation:        
  Pigment Cell Res. 2004 Aug;17(4):413-21       Epub:        
  Not Epub       Abstract:        
  Tyrosinase has a role in melanin synthesis and several defects of the tyrosinase gene lead to albinism. Here, we cloned and...       Delivery Method:        
  Microinjection       Organism or Cell Type:        
  trout, rainbow       Citation Extract:              Boonanuntanasarn S, Yoshizaki G, Iwai K, Takeuchi T. Molecular cloning, gene expression in albino mutants and gene knockdown studies of tyrosinase mRNA in rainbow trout. Pigment Cell Res. 2004 Aug;17(4):413-21.    | 
          
Morpholino Studies in Xenopus Brain Development
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       Citation:        
  Methods Molec Biol. 2013;(1082)2014:155-71. doi:10.1007/978-1-62703-655-9_11       Epub:        
  Not Epub       Abstract:        
  Antisense morpholino oligonucleotides (MOs) have become a valuable method to knock down protein levels, to block mRNA splicing...       Organism or Cell Type:        
  X.laevis & X.tropicalis       Citation Extract:              Bestman JE, Cline HT. Morpholino Studies in Xenopus Brain Development. Methods Molec Biol. 2013;(1082)2014:155-71. doi:10.1007/978-1-62703-655-9_11.    | 
          
Multiple mechanisms mediate motor neuron migration in the zebrafish hindbrain
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       Citation:        
  Dev Neurobiol. 2009 Nov 23. [Epub ahead of print]       Epub:        
  Not Epub       Abstract:        
  The transmembrane protein Van gogh-like 2 (Vangl2) is a component of the noncanonical Wnt/Planar Cell Polarity (PCP) signaling...       Delivery Method:        
  Microinjection       Organism or Cell Type:        
  zebrafish       Citation Extract:              Bingham SM, Sittaramane V, Mapp O, Patil S, Prince VE, Chandrasekhar A. Multiple mechanisms mediate motor neuron migration in the zebrafish hindbrain. Dev Neurobiol. 2009 Nov 23. [Epub ahead of print].    | 
          
Mutations in IRX5 impair craniofacial development and germ cell migration via SDF1
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       Citation:        
  Nat Genet. 2012;[Epub ahead of print] doi:10.1038/ng.2259 N1        Epub:        
  Not Epub       Abstract:        
  Using homozygosity mapping and locus resequencing, we found that alterations in the homeodomain of the IRX5 transcription...       Delivery Method:        
  Microinjection       Organism or Cell Type:        
  Xenopus laevis       Citation Extract:              Bonnard C, Strobl AC, Shboul M, Lee H, Merriman B, Nelson SF, Ababneh OH, Uz E, Guran T, Kayserili H, Hamamy H, Reversade B. Mutations in IRX5 impair craniofacial development and germ cell migration via SDF1. Nat Genet. 2012;[Epub ahead of print] doi:10.1038/ng.2259 N1 .    | 
          
