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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12255 scientific papers returned from the database with the search filters currently being used below.
There are 12255 scientific papers returned from the database with the search filters currently being used below.
Comparative analysis of antisense oligonucleotide analogs for targeted DMD exon 46 skipping in muscle cells
Citation:
Gene Ther. 2004 Sep;11(18):1391-8. Epub:
Not Epub Abstract:
As small molecule drugs for Duchenne muscular dystrophy (DMD), antisense oligonucleotides (AONs) have been shown to restore the... Delivery Method:
Special Delivery Organism or Cell Type:
Cell culture: primary human myoblast Citation Extract: Aartsma-Rus A, Kaman WE, Bremmer-Bout M, Janson AA, Den Dunnen JT, Van Ommen GJ, Van Deutekom JC. Comparative analysis of antisense oligonucleotide analogs for targeted DMD exon 46 skipping in muscle cells. Gene Ther. 2004 Sep;11(18):1391-8.. |
Compound inheritance of a low-frequency regulatory SNP and a rare null mutation in exon-junction complex subunit RBM8A causes TAR syndrome
Citation:
Nat Genet. 2012 Feb 26;44(4):435-9, S1-2. doi: 10.1038/ng.1083 Epub:
Not Epub Abstract:
The exon-junction complex (EJC) performs essential RNA processing tasks1-5. Here, we describe the first human disorder,... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Albers CA, Paul DS, Schulze H, Freson K, Stephens JC, Smethurst PA, Jolley JD, Cvejic A, Kostadima M, Bertone P, Breuning MH, Debili N, Deloukas P, Favier R, Fiedler J, Hobbs CM, Huang N, Hurles ME, Kiddle G, Krapels I, Nurden P, Ruivenkamp CA, Sambrook JG, Smith K, Stemple DL, Strauss G, Thys C, van Geet C, Newbury-Ecob R, Ouwehand WH, Ghevaert C. Compound inheritance of a low-frequency regulatory SNP and a rare null mutation in exon-junction complex subunit RBM8A causes TAR syndrome. Nat Genet. 2012 Feb 26;44(4):435-9, S1-2. doi: 10.1038/ng.1083. |
Conserved Functions for Mos in Eumetazoan Oocyte Maturation Revealed by Studies in a Cnidarian
Citation:
Curr Biol. 2009 Feb 18. [Epub ahead of print] Epub:
Not Epub Abstract:
The kinase Mos, which activates intracellularly the MAP kinase pathway, is a key regulator of animal oocyte meiotic maturation... Organism or Cell Type:
Clytia hemisphaerica Citation Extract: Amiel A, Leclère L, Robert L, Chevalier S, Houliston E. Conserved Functions for Mos in Eumetazoan Oocyte Maturation Revealed by Studies in a Cnidarian. Curr Biol. 2009 Feb 18. [Epub ahead of print]. |
Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) BY NkX2.2 and neurogenin 3
Citation:
J Biol Chem. 2009 Sep 15. [Epub ahead of print] Epub:
Not Epub Abstract:
Nkx2.2 and NeuroD1 are two critical regulators of pancreatic beta cell development. Nkx2.2 is a homeodomain transcription... Organism or Cell Type:
zebrafish Citation Extract: Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L. Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) BY NkX2.2 and neurogenin 3. J Biol Chem. 2009 Sep 15. [Epub ahead of print]. |
Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies
Citation:
Nucleic Acids Res. 2008 Nov;36(20):6343-54. Epub 2008 Sep 16 Epub:
Not Epub Abstract:
Redirecting the splicing machinery through the hybridization of high affinity, RNase H- incompetent oligonucleotide analogs... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: HeLa AntisenseTest System Citation Extract: Abes R, Moulton HM, Clair P, Yang ST, Abes S, Melikov K, Prevot P, Youngblood DS, Iversen PL, Chernomordik LV, Lebleu B. Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies. Nucleic Acids Res. 2008 Nov;36(20):6343-54. Epub 2008 Sep 16. |
Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish
Citation:
Nucleic Acids Res. 2011 Jan 11. [Epub ahead of print] Epub:
Not Epub Abstract:
The nonsense-mediated mRNA decay (NMD) pathway is a highly conserved surveillance mechanism that is present in all eukaryotes.... Organism or Cell Type:
zebrafish Citation Extract: Anastasaki C, Longman D, Capper A, Patton EE, Cáceres JF. Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish. Nucleic Acids Res. 2011 Jan 11. [Epub ahead of print]. |
Disruption of gene function using antisense morpholinos.
Citation:
Methods Cell Biol. 2004;74:699-711 Epub:
Not Epub Abstract:
No abstract available. Citation Extract: Angerer LM, Angerer RC. Disruption of gene function using antisense morpholinos.. Methods Cell Biol. 2004;74:699-711. |
DNA duplex-quadruplex exchange as the basis for a nanomolecular machine
Citation:
Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1569-73. Epub 2003 Feb 06 Epub:
Not Epub Abstract:
There is currently great interest in the design of nanodevices that are capable of performing linear or rotary movements.... Delivery Method:
not applicable Organism or Cell Type:
not applicable Citation Extract: Alberti P, Mergny JL.. DNA duplex-quadruplex exchange as the basis for a nanomolecular machine. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1569-73. Epub 2003 Feb 06. |
Docking protein SNT1 is a critical mediator of fibroblast growth factor signaling during Xenopus embryonic development.
Citation:
Dev Dyn. 2002 Mar;223(2):216-28. Epub:
Not Epub Abstract:
The docking protein SNT1/FRS2 (fibroblast growth factor receptor substrate 2) is implicated in the transmission of... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Akagi K, Park EK, Mood K, Daar IO. Docking protein SNT1 is a critical mediator of fibroblast growth factor signaling during Xenopus embryonic development.. Dev Dyn. 2002 Mar;223(2):216-28.. |
Early development of forebrain gonadotrophin-releasing hormone (GnRH) neurones and the role of GnRH as an autocrine migration factor.
Citation:
J Neuroendocrinol. 2008 Mar;20(3):394-405. doi: 10.1111/j.1365-2826.2008.01654.x. Epub 2008 Jan 17. Epub:
Not Epub Abstract:
Normal migration of the GnRH-I neurones during early development, from the olfactory region to the hypothalamus, is crucial for... Organism or Cell Type:
zebrafish Citation Extract: Abraham E, Palevitch O, Ijiri S, Du SJ, Gothilf Y, Zohar Y. Early development of forebrain gonadotrophin-releasing hormone (GnRH) neurones and the role of GnRH as an autocrine migration factor.. J Neuroendocrinol. 2008 Mar;20(3):394-405. doi: 10.1111/j.1365-2826.2008.01654.x. Epub 2008 Jan 17.. |