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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12092 scientific papers returned from the database with the search filters currently being used below.
There are 12092 scientific papers returned from the database with the search filters currently being used below.
Electrical impedance myography detects dystrophin-related muscle changes in mdx mice
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Citation:
Skelet Muscle. 2023 Nov 18;13(1):19. doi: 10.1186/s13395-023-00331-1 Epub:
Not Epub Abstract:
Background: The lack of functional dystrophin protein in Duchenne muscular dystrophy (DMD) causes chronic skeletal muscle... Delivery Method:
peptide-linked Organism or Cell Type:
mice Citation Extract: Hiyoshi T, Zhao F, Baba R, Hirakawa T, Kuboki R, Suzuki K, Tomimatsu Y, O'Donnell P, Han S, Zach N, Nakashima M. Electrical impedance myography detects dystrophin-related muscle changes in mdx mice. Skelet Muscle. 2023 Nov 18;13(1):19. doi: 10.1186/s13395-023-00331-1. |
Vangl2 deficient zebrafish exhibit hallmarks of neural tube closure defects
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.11.09.566412 Epub:
Not Epub Abstract:
Neural tube defects (NTDs) are among the most devastating and common congenital anomalies worldwide, and the ability to model... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: MacGowan J, Cardenas M, Williams MK. Vangl2 deficient zebrafish exhibit hallmarks of neural tube closure defects. bioRxiv. 2023;[preprint] doi:10.1101/2023.11.09.566412. |
Maternal H3.3-Mediated Paternal Genome Reprogramming Contributes to Minor Zygotic Genome Activation
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.11.07.566007 Epub:
Not Epub Abstract:
In mice, zygotic genome activation (ZGA) is initiated at the late-one-cell stage, accompanied by an extensive incorporation of... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Zhang J, Li X, Cui H, Xiao S, Song E, Zong M, Ling S, Rosenwaks Z, Gao S, Liu X, Kong Q, Wen D. Maternal H3.3-Mediated Paternal Genome Reprogramming Contributes to Minor Zygotic Genome Activation. bioRxiv. 2023;[preprint] doi:10.1101/2023.11.07.566007. |
IRE1-mediated degradation of pre-miR-301a promotes apoptosis through upregulation of GADD45A
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Citation:
Cell Commun Signal. 2023 Nov 9;21(1):322. doi: 10.1186/s12964-023-01349-0 Epub:
Not Epub Abstract:
The unfolded protein response is a survival signaling pathway that is induced during various types of ER stress. Here, we... Organism or Cell Type:
cell culture: 16HBE140 Citation Extract: Gebert M, Bartoszewska S, Opalinski L, Collawn JF, Bartoszewski R. IRE1-mediated degradation of pre-miR-301a promotes apoptosis through upregulation of GADD45A. Cell Commun Signal. 2023 Nov 9;21(1):322. doi: 10.1186/s12964-023-01349-0. |
The conserved wobble uridine tRNA thiolase Ctu1 is required to sustain development and differentiation
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.11.08.566201 Epub:
Not Epub Abstract:
Recent studies have revealed that tRNA modification is an important epigenetic mechanism involved in gene expression. Cytosolic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: YZW Yu, CQ Wang, Y Wang, H Shi, ZL Zhou. The conserved wobble uridine tRNA thiolase Ctu1 is required to sustain development and differentiation. bioRxiv. 2023;[preprint] doi:10.1101/2023.11.08.566201. |
Optimization and Safety Results of E1v1.11: a morpholino antisense oligonucleotide therapeutic for Spinal Muscular Atrophy
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Citation:
MDA Conference Abstracts. 2024;Poster 85 Epub:
Not Epub Abstract:
Spinal Muscular Atrophy (SMA) is an autosomal recessive disorder that is the leading genetic cause of infantile death,... Citation Extract: Oconnor S, Hansen H, Osman E, Kaifer KD, Morcos P, Kacher M, Beatty D, Lorson C. Optimization and Safety Results of E1v1.11: a morpholino antisense oligonucleotide therapeutic for Spinal Muscular Atrophy. MDA Conference Abstracts. 2024;Poster 85. |
Proenkephalin-A secreted by renal proximal tubules functions as a brake in kidney regeneration
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Citation:
Nat Commun. 2023 Nov 7;14(1):7167. doi: 10.1038/s41467-023-42929-5 Epub:
Not Epub Abstract:
Organ regeneration necessitates precise coordination of accelerators and brakes to restore organ function. However, the... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Liu C, Liu X, He Z, Zhang J, Tan X, Yang W, Zhang Y, Yu T, Liao S, Dai L, Xu Z, Li F, Huang Y, Zhao J. Proenkephalin-A secreted by renal proximal tubules functions as a brake in kidney regeneration. Nat Commun. 2023 Nov 7;14(1):7167. doi: 10.1038/s41467-023-42929-5. |
Abstract 14239: Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve
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Citation:
Circulation. 2023;148(Supp 1):A14239 Epub:
Not Epub Abstract:
Background: Extracellular matrix (ECM) is involved in aortic valve development and aortic valve anomaly. ADAMTS gene mediated... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin Y, Yang Q, Lin X, Liu X, Kong X, Zhu L, Zhou B, Wang Y, Peng J, Zhu W, Wang J. Abstract 14239: Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve. Circulation. 2023;148(Supp 1):A14239 . |
Kif21a deficiency leads to impaired glomerular filtration barrier function
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Citation:
Sci Rep. 2023 Nov 6;13(1):19161. doi: 10.1038/s41598-023-46270-1 Epub:
Not Epub Abstract:
The renal glomerulus represents the major filtration body of the vertebrate nephron and is responsible for urine production and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Riedmann H, Kayser S, Helmstädter M, Epting D, Bergmann C. Kif21a deficiency leads to impaired glomerular filtration barrier function. Sci Rep. 2023 Nov 6;13(1):19161. doi: 10.1038/s41598-023-46270-1. |
Her6 and Prox1a are novel regulators of photoreceptor regeneration in the zebrafish retina
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Citation:
PLoS Genet. 2023 Nov 6;19(11):e1011010. doi: 10.1371/journal.pgen.1011010. Online ahead of print Epub:
Not Epub Abstract:
Damage to light-sensing photoreceptors (PRs) occurs in highly prevalent retinal diseases. As humans cannot regenerate new PRs,... Delivery Method:
injection then electroporation Organism or Cell Type:
zebrafish Citation Extract: Veen K, Krylov A, Yu S, He J, Boyd P, Hyde DR, Mantamadiotis T, Cheng LY, Jusuf PR. Her6 and Prox1a are novel regulators of photoreceptor regeneration in the zebrafish retina. PLoS Genet. 2023 Nov 6;19(11):e1011010. doi: 10.1371/journal.pgen.1011010. Online ahead of print. |