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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12152 scientific papers returned from the database with the search filters currently being used below.

A genetic modifier links integrin α5 to the phenotypic variation in fibronectin 1a mutant zebrafish

Authors:
Capon SJ, Maroufidou A, Feltes M, Xu Y, Matharoo DK, Jülich D, Holley SA, Farber SA, Stainier DYR
Citation:
PLoS Genet. 2025 Jun 23;21(6):e1011747. doi: 10.1371/journal.pgen.1011747. PMID: 40549824; PMCID: PMC12212883
Epub:
Not Epub
Abstract:
Phenotypic variation is often observed in individuals with the same mutation. However, the mechanisms that contribute to this...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12212883/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Capon SJ, Maroufidou A, Feltes M, Xu Y, Matharoo DK, Jülich D, Holley SA, Farber SA, Stainier DYR. A genetic modifier links integrin α5 to the phenotypic variation in fibronectin 1a mutant zebrafish. PLoS Genet. 2025 Jun 23;21(6):e1011747. doi: 10.1371/journal.pgen.1011747. PMID: 40549824; PMCID: PMC12212883.

Differential sensitivity of midline development to mitosis during and after primitive streak extension

Authors:
Zhao Z, Asai R, Mikawa T
Citation:
Dev Dyn. 2025 Jun 12. doi: 10.1002/dvdy.70045. Epub ahead of print. PMID: 40503790
Epub:
Not Epub
Abstract:
Background: Midline establishment is a fundamental process during early embryogenesis for Bilaterians. Midline morphogenesis...
Link:
https://anatomypubs.onlinelibrary.wiley.com/doi/full/10.1002/dvdy.70045
Delivery Method:
electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Zhao Z, Asai R, Mikawa T. Differential sensitivity of midline development to mitosis during and after primitive streak extension. Dev Dyn. 2025 Jun 12. doi: 10.1002/dvdy.70045. Epub ahead of print. PMID: 40503790.

The human RIF1-Long isoform interacts with BRCA1 to promote recombinational fork repair under DNA replication stress

Authors:
Dong Q, Day M, Saito Y, Parker E, Watts LP, Kanemaki MT, Oliver AW, Pearl LH, Hiraga SI, Donaldson AD
Citation:
Nat Commun. 2025 Jul 1;16(1):5820. doi: 10.1038/s41467-025-60817-y. PMID: 40595496
Epub:
Not Epub
Abstract:
RIF1 is a multifunctional protein that regulates DNA replication and repair. RIF1-deficient cells are hypersensitive to DNA...
Link:
https://www.nature.com/articles/s41467-025-60817-y
Delivery Method:
Endo-Porter PEG
Organism or Cell Type:
hTERT RPE-1 cells
Citation Extract:
Dong Q, Day M, Saito Y, Parker E, Watts LP, Kanemaki MT, Oliver AW, Pearl LH, Hiraga SI, Donaldson AD. The human RIF1-Long isoform interacts with BRCA1 to promote recombinational fork repair under DNA replication stress. Nat Commun. 2025 Jul 1;16(1):5820. doi: 10.1038/s41467-025-60817-y. PMID: 40595496.

Chordin-mediated BMP shuttling patterns the secondary body axis in a cnidarian

Authors:
Mörsdorf D, Prünster MM, Knabl P, Genikhovich G
Citation:
Sci Adv. 2025 Jun 13;11(24):eadu6347. doi: 10.1126/sciadv.adu6347. Epub 2025 Jun 13. PMID: 40512865; PMCID: PMC12164971
Epub:
Not Epub
Abstract:
Bone morphogenetic protein (BMP) signaling patterns secondary body axes throughout Bilateria and in the bilaterally symmetric...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12164971/
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella embryo
Citation Extract:
Mörsdorf D, Prünster MM, Knabl P, Genikhovich G. Chordin-mediated BMP shuttling patterns the secondary body axis in a cnidarian. Sci Adv. 2025 Jun 13;11(24):eadu6347. doi: 10.1126/sciadv.adu6347. Epub 2025 Jun 13. PMID: 40512865; PMCID: PMC12164971.

Genetic compensation in podocalyxin-like mutants during zebrafish liver development

Authors:
Ross AN, Miscik NM, Kalasekar SM, Harris JD, Tran M, Saxena A, Baker SA, Evason KJ
Citation:
2025 eLife14:RP106460.
Epub:
Not Epub
Abstract:
Hepatic stellate cells (HSCs) are critical for normal liver development and regeneration. Podocalyxin-like (podxl) is highly...
Link:
https://elifesciences.org/reviewed-preprints/106460v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ross AN, Miscik NM, Kalasekar SM, Harris JD, Tran M, Saxena A, Baker SA, Evason KJ. Genetic compensation in podocalyxin-like mutants during zebrafish liver development. 2025 eLife14:RP106460. .

High-Throughput Screening Identifies Bisphenol P as a Potent Cardiotoxin, Inducing Cardiotoxicity through Apoptosis and the NF-κB Pathway

Authors:
Wang J, Magnuson JT, Feng Y, Zhao W, Gao C, Zheng C, Qiu W
Citation:
Environ Sci Technol. 2025 Jul 29;59(29):14870-14880. doi: 10.1021/acs.est.5c00573. Epub 2025 Jun 26. PMID: 40570244
Epub:
Not Epub
Abstract:
The increasing use of plastic additives, particularly bisphenols (BPs), has raised significant concerns about their potential...
Link:
https://pubs.acs.org/doi/10.1021/acs.est.5c00573
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang J, Magnuson JT, Feng Y, Zhao W, Gao C, Zheng C, Qiu W. High-Throughput Screening Identifies Bisphenol P as a Potent Cardiotoxin, Inducing Cardiotoxicity through Apoptosis and the NF-κB Pathway. Environ Sci Technol. 2025 Jul 29;59(29):14870-14880. doi: 10.1021/acs.est.5c00573. Epub 2025 Jun 26. PMID: 40570244.

Foxj3 represses TGF-β signals-responsive transcriptions in Xenopus early development

Authors:
Yoon GH, Kim MS, Choi SC
Citation:
Genes Genomics. 2025 Jun 16. doi: 10.1007/s13258-025-01654-7. Epub ahead of print. PMID: 40522413
Epub:
Not Epub
Abstract:
Background: Forkhead box (Fox) proteins belong to a large family of transcription factors characterized by a highly conserved...
Link:
https://link.springer.com/article/10.1007/s13258-025-01654-7
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Yoon GH, Kim MS, Choi SC. Foxj3 represses TGF-β signals-responsive transcriptions in Xenopus early development. Genes Genomics. 2025 Jun 16. doi: 10.1007/s13258-025-01654-7. Epub ahead of print. PMID: 40522413.

The indispensable role of Mediator complex subunit 27 during neurodevelopment

Authors:
Li X, Yiliyaer N, Guo T, Zhao H, Lei Y, Gu S
Citation:
Cell Biosci. 2025 Jun 16;15(1):83. doi: 10.1186/s13578-025-01425-7. PMID: 40524219; PMCID: PMC12172316
Epub:
Not Epub
Abstract:
Background: MED27 is a subunit of the Mediator complex, a highly conserved protein assembly that initiates transcription by...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12172316/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li X, Yiliyaer N, Guo T, Zhao H, Lei Y, Gu S. The indispensable role of Mediator complex subunit 27 during neurodevelopment. Cell Biosci. 2025 Jun 16;15(1):83. doi: 10.1186/s13578-025-01425-7. PMID: 40524219; PMCID: PMC12172316.

Genetic compensation highlights the importance of neural cell adhesion molecule Ncam1 paralogs in balancing signaling pathways during zebrafish lateral line development

Authors:
Lange A, Bastmeyer M, Bentrop J
Citation:
Eur J Cell Biol. 2025 Sep;104(3):151500. doi: 10.1016/j.ejcb.2025.151500. Epub 2025 Jun 19. PMID: 40570383.
Epub:
Not Epub
Abstract:
The neural cell adhesion molecule NCAM1 is essential for neuronal development and enables organized cell migration, axon growth...
Link:
https://www.sciencedirect.com/science/article/pii/S0171933525000251
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lange A, Bastmeyer M, Bentrop J. Genetic compensation highlights the importance of neural cell adhesion molecule Ncam1 paralogs in balancing signaling pathways during zebrafish lateral line development. Eur J Cell Biol. 2025 Sep;104(3):151500. doi: 10.1016/j.ejcb.2025.151500. Epub 2025 Jun 19. PMID: 40570383..

Antisense Oligonucleotides Targeting the SARS-CoV-2 Nucleocapsid Gene Decrease Viral Titers in Hamsters

Authors:
Fitzpatrick C, Meunier N, Lepoder S, Dhorne-Pollet S, Da Costa B, Klonjkowki B, Eléouët J-F, Burzio VA, Delmas B, Barrey E
Citation:
Molecular Therapy - Nucleic Acids (2025)
Epub:
Not Epub
Abstract:
SARS-CoV-2 is a positive, single-stranded RNA coronavirus responsible for the COVID-19 pandemic. The emergence of new variants...
Link:
https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(25)00166-0
Delivery Method:
Lipofectamine 2000 for cell culture; intranasal for hamsters
Organism or Cell Type:
cell culture: HEK-293T/ACE2; in vivo: Syrian hamsters
Citation Extract:
Fitzpatrick C, Meunier N, Lepoder S, Dhorne-Pollet S, Da Costa B, Klonjkowki B, Eléouët J-F, Burzio VA, Delmas B, Barrey E. Antisense Oligonucleotides Targeting the SARS-CoV-2 Nucleocapsid Gene Decrease Viral Titers in Hamsters. Molecular Therapy - Nucleic Acids (2025).

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