You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12092 scientific papers returned from the database with the search filters currently being used below.

ERBB3 deficiency causes a multisystemic syndrome in human patient and zebrafish

Authors:
Liu K, Chen R, Zhang M, Gong Y, Wang Y, Cai W
Citation:
Clin Genet. 2023 Nov 27. doi: 10.1111/cge.14462. Online ahead of print
Epub:
Yes
Abstract:
The Erb-B2 receptor tyrosine kinase 3 (ERBB3) gene was first identified as a cause of lethal congenital contracture syndrome (...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1111/cge.14462
Organism or Cell Type:
zebrafish
Citation Extract:
Liu K, Chen R, Zhang M, Gong Y, Wang Y, Cai W. ERBB3 deficiency causes a multisystemic syndrome in human patient and zebrafish. Clin Genet. 2023 Nov 27. doi: 10.1111/cge.14462. Online ahead of print.

A collagen-rich arch in the urochordate notochord coordinates cell shaping and multi-tissue elongation

Authors:
Peng H, Qiao J, Wang G, Shi W, Xia F, Qiao R, Dong B
Citation:
Curr Biol. 2023 Nov 14:S0960-9822(23)01515-4. doi: 10.1016/j.cub.2023.11.001. Online ahead of print
Epub:
Not Epub
Abstract:
Cell and tissue reshaping is crucial for coordinating three-dimensional pattern formation, in which the size and shape of the...
Link:
https://www.cell.com/current-biology/fulltext/S0960-9822(23)01515-4
Delivery Method:
microinjection
Organism or Cell Type:
Ciona savignyi (ascidian)
Citation Extract:
Peng H, Qiao J, Wang G, Shi W, Xia F, Qiao R, Dong B. A collagen-rich arch in the urochordate notochord coordinates cell shaping and multi-tissue elongation. Curr Biol. 2023 Nov 14:S0960-9822(23)01515-4. doi: 10.1016/j.cub.2023.11.001. Online ahead of print.

mCherry on Top: A Positive Read-Out Cellular Platform for Screening DMD Exon Skipping Xenopeptide-PMO Conjugates

Authors:
Lessl AL, Pöhmerer J, Lin Y, Wilk U, Höhn M, Hörterer E, Wagner E, Lächelt U
Citation:
Bioconjug Chem. 2023 Nov 22. doi: 10.1021/acs.bioconjchem.3c00408. Online ahead of print
Epub:
Not Epub
Abstract:
Phosphorodiamidate morpholino oligomers (PMOs) are a special type of antisense oligonucleotides (ASOs) that can be used as...
Link:
https://pubs.acs.org/doi/10.1021/acs.bioconjchem.3c00408
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: HeLa; mice
Citation Extract:
Lessl AL, Pöhmerer J, Lin Y, Wilk U, Höhn M, Hörterer E, Wagner E, Lächelt U. mCherry on Top: A Positive Read-Out Cellular Platform for Screening DMD Exon Skipping Xenopeptide-PMO Conjugates. Bioconjug Chem. 2023 Nov 22. doi: 10.1021/acs.bioconjchem.3c00408. Online ahead of print.

Induction of Reproductive Sterility in Coho Salmon (Oncorhynchus kisutch) by an Immersion-Based Gene Silencing Technology

Authors:
Xu L, Zhao M, Zohar Y, Wong T-T
Citation:
J Mar Sci Eng. 2023;11:2208. doi:10.3390/jmse11122208
Epub:
Not Epub
Abstract:
Undesired maturation and reproduction are major challenges in fish aquaculture regarding genetic introgression, precocious...
Link:
https://www.mdpi.com/2077-1312/11/12/2208
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Oncorhynchus kisutch (coho salmon)
Citation Extract:
Xu L, Zhao M, Zohar Y, Wong T-T. Induction of Reproductive Sterility in Coho Salmon (Oncorhynchus kisutch) by an Immersion-Based Gene Silencing Technology. J Mar Sci Eng. 2023;11:2208. doi:10.3390/jmse11122208.

Induction of germ cell-deficiency in grass puffer by dead end 1 gene knockdown for use as a recipient in surrogate production of tiger puffer

Authors:
Yoshikawa H, Ino Y, Kishimoto K, Koyakumaru H, Saito T, Kinoshita M, Yoshiura Y
Citation:
Aquaculture. 2020;526:735385. doi:10.1016/j.aquaculture.2020.735385
Epub:
Not Epub
Abstract:
The surrogate broodstock technique produces donor-derived gametes via transplantation of germ cells into surrogate fish. The...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0044848619335367
Delivery Method:
microinjection
Organism or Cell Type:
Takifugu alboplumbeus (grass puffer)
Citation Extract:
Yoshikawa H, Ino Y, Kishimoto K, Koyakumaru H, Saito T, Kinoshita M, Yoshiura Y. Induction of germ cell-deficiency in grass puffer by dead end 1 gene knockdown for use as a recipient in surrogate production of tiger puffer. Aquaculture. 2020;526:735385. doi:10.1016/j.aquaculture.2020.735385.

UGT1A1 morpholino antisense oligonucleotides produce mild unconjugated hyperbilirubinemia in cyclosprin A-induced cardiovascular disorders in BLC57 mice

Authors:
Marghani BH, Ateya AI, Othman BH, Rizk MA, El-Adl M
Citation:
Environ Toxicol Pharmacol 2023 Nov 18:104321. doi: 10.1016/j.etap.2023.104321. Online ahead of print
Epub:
Yes
Abstract:
This study aimed to investigate the induction of mild unconjugated hyperbilirubinemia in hepatic UGT1A1 inhibition by...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1382668923002636
Delivery Method:
intravenous (i.v.)
Organism or Cell Type:
mice
Citation Extract:
Marghani BH, Ateya AI, Othman BH, Rizk MA, El-Adl M. UGT1A1 morpholino antisense oligonucleotides produce mild unconjugated hyperbilirubinemia in cyclosprin A-induced cardiovascular disorders in BLC57 mice. Environ Toxicol Pharmacol 2023 Nov 18:104321. doi: 10.1016/j.etap.2023.104321. Online ahead of print.

Embryo-scale reverse genetics at single-cell resolution

Authors:
Saunders LM, Srivatsan SR, Duran M, Dorrity MW, Ewing B, Linbo TH, Shendure J, Raible DW, Moens CB, Kimelman D, Trapnell C
Citation:
Nature. 2023 Nov 15. doi: 10.1038/s41586-023-06720-2. Online ahead of print
Epub:
Yes
Abstract:
The maturation of single-cell transcriptomic technologies has facilitated the generation of comprehensive cellular atlases from...
Link:
https://www.nature.com/articles/s41586-023-06720-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Saunders LM, Srivatsan SR, Duran M, Dorrity MW, Ewing B, Linbo TH, Shendure J, Raible DW, Moens CB, Kimelman D, Trapnell C. Embryo-scale reverse genetics at single-cell resolution. Nature. 2023 Nov 15. doi: 10.1038/s41586-023-06720-2. Online ahead of print.

asb5a/asb5b Double Knockout Affects Zebrafish Cardiac Contractile Function

Authors:
Cai W, Wang Y, Luo Y, Gao L, Zhang J, Jiang Z, Fan X, Li F, Xie Y, Wu X, Li Y, Yuan W.
Citation:
Int J Mol Sci. 2023;24(22):16364. doi:10.3390/ijms242216364
Epub:
Not Epub
Abstract:
Ankyrin repeat and suppression-of-cytokine-signaling box (Asb) proteins, a subset of ubiquitin ligase E3, include Asb5 with six...
Link:
https://www.mdpi.com/1422-0067/24/22/16364
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cai W, Wang Y, Luo Y, Gao L, Zhang J, Jiang Z, Fan X, Li F, Xie Y, Wu X, Li Y, Yuan W. . asb5a/asb5b Double Knockout Affects Zebrafish Cardiac Contractile Function. Int J Mol Sci. 2023;24(22):16364. doi:10.3390/ijms242216364 .

Combined RhoA Morpholino and ChABC Treatment Protects Identified Lamprey Neurons from Retrograde Apoptosis after Spinal Cord Injury

Authors:
Hu J, Zhang KG, Rodemer W, Jin L-Q, Selzer ME
Citation:
Front Cell Neurosci. 2023;17:[Epub] doi:10.3389/fncel.2023.1292012
Epub:
Not Epub
Abstract:
Previously, we reported that RhoA knockdown by morpholino antisense oligonucleotides (MOs), and enzymatic digestion of...
Link:
https://www.frontiersin.org/articles/10.3389/fncel.2023.1292012/abstract
Delivery Method:
Gelfoam at lesion
Organism or Cell Type:
lamprey
Citation Extract:
Hu J, Zhang KG, Rodemer W, Jin L-Q, Selzer ME. Combined RhoA Morpholino and ChABC Treatment Protects Identified Lamprey Neurons from Retrograde Apoptosis after Spinal Cord Injury. Front Cell Neurosci. 2023;17:[Epub] doi:10.3389/fncel.2023.1292012.

Anticancer effect of hUC-MSC-derived exosome-mediated delivery of PMO-miR-146b-5p in colorectal cancer

Authors:
Yu S, Liao R, Bai L, Guo M, Zhang Y, Zhang Y, Yang Q, Song Y, Li Z, Meng Q, Wang S, Huang X
Citation:
Drug Deliv Transl Res. 2023 Nov 17. doi: 10.1007/s13346-023-01469-7. Online ahead of print
Epub:
Not Epub
Abstract:
Antisense oligonucleotide (ASO) is a novel therapeutic platform for targeted cancer therapy. Previously, we have demonstrated...
Link:
https://link.springer.com/article/10.1007/s13346-023-01469-7
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: SW620, xenograft mice
Citation Extract:
Yu S, Liao R, Bai L, Guo M, Zhang Y, Zhang Y, Yang Q, Song Y, Li Z, Meng Q, Wang S, Huang X. Anticancer effect of hUC-MSC-derived exosome-mediated delivery of PMO-miR-146b-5p in colorectal cancer. Drug Deliv Transl Res. 2023 Nov 17. doi: 10.1007/s13346-023-01469-7. Online ahead of print.

Pages