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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12184 scientific papers returned from the database with the search filters currently being used below.

Cooperative Roles of Pds5a and Pds5b Constrain Long-Range Chromatin Interactions in Vertebrate Embryos

Authors:
Ikeda S, Takeda H, Nakamura R
Citation:
Dev Growth Differ. 2026 Apr;68(3):e70054. doi: 10.1111/dgd.70054. PMID: 41994921; PMCID: PMC13088002
Epub:
Not Epub
Abstract:
Three-dimensional (3D) genome organization is dynamically restructured during early vertebrate development, yet how chromatin...
Link:
https://onlinelibrary.wiley.com/doi/10.1111/dgd.70054
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Ikeda S, Takeda H, Nakamura R. Cooperative Roles of Pds5a and Pds5b Constrain Long-Range Chromatin Interactions in Vertebrate Embryos. Dev Growth Differ. 2026 Apr;68(3):e70054. doi: 10.1111/dgd.70054. PMID: 41994921; PMCID: PMC13088002.

Delivery and uptake of free and liposome-encapsulated cholesterol-conjugated antisense oligonucleotides in Atlantic salmon sperm: insights from high-resolution imaging

Authors:
Swain JK, Wolfson DL, Swain T, Flaten GE, Škalko-Basnet N, Ahluwalia BS, Tveiten H
Citation:
BMC Vet Res. 2026 Apr 17. doi: 10.1186/s12917-026-05465-0. Epub ahead of print. PMID: 41992206
Epub:
Not Epub
Abstract:
The development of efficient methods for large-scale delivery of antisense molecules to Atlantic salmon (Salmo salar L.) eggs...
Link:
https://link.springer.com/article/10.1186/s12917-026-05465-0
Delivery Method:
cholesterol-conjugated PMO and liposome-encapsulated cholesterol-conjugated PMO
Organism or Cell Type:
salmon spermatozoa
Citation Extract:
Swain JK, Wolfson DL, Swain T, Flaten GE, Škalko-Basnet N, Ahluwalia BS, Tveiten H. Delivery and uptake of free and liposome-encapsulated cholesterol-conjugated antisense oligonucleotides in Atlantic salmon sperm: insights from high-resolution imaging. BMC Vet Res. 2026 Apr 17. doi: 10.1186/s12917-026-05465-0. Epub ahead of print. PMID: 41992206.

Vps34 Knockdown Alleviated the Long-Term Effect of Nano-Alumina on Cognitive Impairment in Zebrafish When in Embryos

Authors:
Zhang Y, Zhao J, Huang T, Gao X, Zhang L, Wang Y, Guo X, Zhang L, Niu Q, Zhang Q
Citation:
J Appl Toxicol. 2026 Apr 9. doi: 10.1002/jat.70186. Epub ahead of print. PMID: 41956485
Epub:
Not Epub
Abstract:
Nano-alumina (AlNPs) exposure induced learning and memory impairment, which was associated with over-activation of mitophagy....
Link:
https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jat.70186
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Y, Zhao J, Huang T, Gao X, Zhang L, Wang Y, Guo X, Zhang L, Niu Q, Zhang Q. Vps34 Knockdown Alleviated the Long-Term Effect of Nano-Alumina on Cognitive Impairment in Zebrafish When in Embryos. J Appl Toxicol. 2026 Apr 9. doi: 10.1002/jat.70186. Epub ahead of print. PMID: 41956485.

Advancements from the EVOLVE study for assessing real-world experience with eteplirsen, golodirsen and casimersen for the treatment of DMD

Authors:
Tian C, Grabich S, Veerapandiyan A, Scharf RJ, Santra S, Hornibrook S, Drummond K, Sehinovych I, Waldrop M
Citation:
J Comp Eff Res. 2026 Apr 10:e250108. doi: 10.57264/cer-2025-0108. Epub ahead of print. PMID: 41961051
Epub:
Not Epub
Abstract:
Aim: Eteplirsen, golodirsen and casimersen are phosphorodiamidate morpholino oligomers (PMOs) that have received, based on...
Link:
https://becarispublishing.com/doi/10.57264/cer-2025-0108
Delivery Method:
intravenous (i.v.) infusion
Organism or Cell Type:
human
Citation Extract:
Tian C, Grabich S, Veerapandiyan A, Scharf RJ, Santra S, Hornibrook S, Drummond K, Sehinovych I, Waldrop M. Advancements from the EVOLVE study for assessing real-world experience with eteplirsen, golodirsen and casimersen for the treatment of DMD. J Comp Eff Res. 2026 Apr 10:e250108. doi: 10.57264/cer-2025-0108. Epub ahead of print. PMID: 41961051.

Alternative probe chemistries for single-molecule analysis of long non-coding RNA

Authors:
Pai KR, Martin AM, Kadrmas M, Widom JR
Citation:
J Biol Chem. 2026 Apr 9:111441. doi: 10.1016/j.jbc.2026.111441. Epub ahead of print. PMID: 41966267
Epub:
Not Epub
Abstract:
Single-molecule microscopy has been widely used to study the structure and dynamics of RNA, but extension to larger systems...
Link:
https://www.jbc.org/article/S0021-9258(26)00311-X/fulltext
Delivery Method:
None
Organism or Cell Type:
RNA probe
Citation Extract:
Pai KR, Martin AM, Kadrmas M, Widom JR. Alternative probe chemistries for single-molecule analysis of long non-coding RNA. J Biol Chem. 2026 Apr 9:111441. doi: 10.1016/j.jbc.2026.111441. Epub ahead of print. PMID: 41966267.

Dysregulated Protease Homeostasis Defines Primary FSGS

Authors:
Schmidt J, Sopel N, Rist C, Ohs A, Dawid L, Simm S, Catanese L, Rupprecht H, Jobst-Schwan T, Lehmann J, Daniel C, Kalkhof S, Schiffer M, Müller-Deile J
Citation:
Kidney360. 2026 Mar 1;7(3):487-500. doi: 10.34067/KID.0000001021. Epub 2025 Nov 10. PMID: 41910486
Epub:
Not Epub
Abstract:
Serum proteomics reveals reduced serpin family A member 1 (SERPINA1) in primary FSGS, distinguishing it from other proteinuric...
Link:
https://journals.lww.com/kidney360/fulltext/2026/03000/dysregulated_protease_homeostasis_defines_primary.8.aspx
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schmidt J, Sopel N, Rist C, Ohs A, Dawid L, Simm S, Catanese L, Rupprecht H, Jobst-Schwan T, Lehmann J, Daniel C, Kalkhof S, Schiffer M, Müller-Deile J. Dysregulated Protease Homeostasis Defines Primary FSGS. Kidney360. 2026 Mar 1;7(3):487-500. doi: 10.34067/KID.0000001021. Epub 2025 Nov 10. PMID: 41910486.

The nBAF complex subunit CREST/SS18L1 regulates hippocampal memory processes via tyrosine 397 and histone acetyltransferase CBP

Authors:
Garcia FG, Farias de Albuquerque M, Johnson V, Kramár E, Changizi K, Abdelkarim S, Augustynski AS, Matheos DP, Picone J, Fetterly TL, Rodriguez A, Childs J, Gomez-Arboledas A, Winter J, Heller E, Baldi P, Wood MA
Citation:
Cell Rep. 2026 Mar 25;45(4):117158. doi: 10.1016/j.celrep.2026.117158. Epub ahead of print. PMID: 41886450
Epub:
Not Epub
Abstract:
Chromatin-modifying and -remodeling machineries are important for learning-induced transcriptional activity, yet it remains...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(26)00236-6
Delivery Method:
Vivo-Morpholino; bilateral infusion into the dorsal hippocampus
Organism or Cell Type:
C57BL/6J & CBP conditional knockout mice
Citation Extract:
Garcia FG, Farias de Albuquerque M, Johnson V, Kramár E, Changizi K, Abdelkarim S, Augustynski AS, Matheos DP, Picone J, Fetterly TL, Rodriguez A, Childs J, Gomez-Arboledas A, Winter J, Heller E, Baldi P, Wood MA. The nBAF complex subunit CREST/SS18L1 regulates hippocampal memory processes via tyrosine 397 and histone acetyltransferase CBP. Cell Rep. 2026 Mar 25;45(4):117158. doi: 10.1016/j.celrep.2026.117158. Epub ahead of print. PMID: 41886450.

Blood vessel-resident macrophages safeguard blood and vessel integrity in zebrafish

Authors:
Weijts B, Demmers JAA & Robin C
Citation:
Nat Immunol (2026). https://doi.org/10.1038/s41590-026-02481-y
Epub:
Not Epub
Abstract:
Tissue-resident macrophages populate nearly all organs, where they adopt tissue-specific roles essential for immune defense,...
Link:
https://www.nature.com/articles/s41590-026-02481-y
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weijts B, Demmers JAA & Robin C. Blood vessel-resident macrophages safeguard blood and vessel integrity in zebrafish. Nat Immunol (2026). https://doi.org/10.1038/s41590-026-02481-y.

Role of Glutamate Receptor-Related Genes in Myopia Occurrence and Visual Development

Authors:
Wang R, Tao D, Lu J, Li J, Liu X, Chen C
Citation:
Curr Eye Res. 2026 Mar 10:1-11. doi: 10.1080/02713683.2026.2637650. Epub ahead of print. PMID: 41804850
Epub:
Not Epub
Abstract:
Purpose: Abnormal expression of glutamate receptors is believed to be associated with myopia. However, it is currently unclear...
Link:
https://www.tandfonline.com/doi/full/10.1080/02713683.2026.2637650
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang R, Tao D, Lu J, Li J, Liu X, Chen C. Role of Glutamate Receptor-Related Genes in Myopia Occurrence and Visual Development. Curr Eye Res. 2026 Mar 10:1-11. doi: 10.1080/02713683.2026.2637650. Epub ahead of print. PMID: 41804850.

TRIM7-mediated autophagy-lysosomal signaling is essential for preimplantation development in mice

Authors:
Khan S, Yan F, Li W, Guo J, Gu X, Tang Z, Bibi U, Dong X, Chen L, Yao Y, Xu J
Citation:
J Transl Med. 2026 Mar 17. doi: 10.1186/s12967-026-07963-z. Epub ahead of print. PMID: 41845426
Epub:
Not Epub
Abstract:
Background: Pre-implantation development in mammals requires precise coordination of zygote genome activation (ZGA), cleavage...
Link:
https://link.springer.com/article/10.1186/s12967-026-07963-z
Delivery Method:
Vivo-Morpholino culture
Organism or Cell Type:
mouse zygote
Citation Extract:
Khan S, Yan F, Li W, Guo J, Gu X, Tang Z, Bibi U, Dong X, Chen L, Yao Y, Xu J. TRIM7-mediated autophagy-lysosomal signaling is essential for preimplantation development in mice. J Transl Med. 2026 Mar 17. doi: 10.1186/s12967-026-07963-z. Epub ahead of print. PMID: 41845426.

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