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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Morpholino oligonucleotide knockdown of the extracellular calcium-sensing receptor impairs early skeletal development in zebrafish

Authors:
Herberger AL, Loretz CA
Citation:
Comp Biochem Physiol A Mol Integr Physiol. 2013 Aug 1. doi:pii: S1095-6433(13)00205-5. 10.1016/j.cbpa.2013.07.027. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The complex vertebrate skeleton depends on regulated cell activities to lay down protein matrix and mineral components of bone...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Herberger AL, Loretz CA. Morpholino oligonucleotide knockdown of the extracellular calcium-sensing receptor impairs early skeletal development in zebrafish. Comp Biochem Physiol A Mol Integr Physiol. 2013 Aug 1. doi:pii: S1095-6433(13)00205-5. 10.1016/j.cbpa.2013.07.027. [Epub ahead of print].

Morpholino oligos: making sense of antisense?

Authors:
Heasman J
Citation:
Dev Biol. 2002 Mar 15;243(2):209-14
Epub:
Not Epub
Abstract:
Since morpholino oligos were first introduced as a means to inhibit gene function in embryos, in the Spring of 2000, they have...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Heasman J. Morpholino oligos: making sense of antisense?. Dev Biol. 2002 Mar 15;243(2):209-14.

Muscular dystrophy candidate gene FRG1 is critical for muscle development

Authors:
Hanel ML, Wuebbles RD, Jones PL
Citation:
Dev Dyn. 2008 Dec 18. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The leading candidate gene responsible for facioscapulohumeral muscular dystrophy (FSHD) is FRG1 (FSHD region gene 1). However...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hanel ML, Wuebbles RD, Jones PL. Muscular dystrophy candidate gene FRG1 is critical for muscle development. Dev Dyn. 2008 Dec 18. [Epub ahead of print].

Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model

Authors:
He S, Lamers GE, Beenakker JW, Cui C, Ghotra VP, Danen EH, Meijer AH, Spaink HP, Snaar-Jagalska BE
Citation:
J Pathol. 2012 Aug;227(4):431-45. doi: 10.1002/path.4013. Epub 2012 Jul 3
Epub:
Not Epub
Abstract:
Inhibition of VEGF signalling effectively suppresses localized tumour growth but accelerates tumour invasiveness and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
He S, Lamers GE, Beenakker JW, Cui C, Ghotra VP, Danen EH, Meijer AH, Spaink HP, Snaar-Jagalska BE. Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model. J Pathol. 2012 Aug;227(4):431-45. doi: 10.1002/path.4013. Epub 2012 Jul 3.

no tail integrates two modes of mesoderm induction

Authors:
Harvey SA, Tümpel S, Dubrulle J, Schier AF, Smith JC
Citation:
Development. 2010 Apr;137(7):1127-35
Epub:
Not Epub
Abstract:
During early zebrafish development the nodal signalling pathway patterns the embryo into three germ layers, in part by inducing...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Harvey SA, Tümpel S, Dubrulle J, Schier AF, Smith JC. no tail integrates two modes of mesoderm induction. Development. 2010 Apr;137(7):1127-35.

Oocyte triplet pairing for electrophysiological investigation of gap junctional coupling

Authors:
Hayar A, Charlesworth A, Garcia-Rill E
Citation:
J Neurosci Methods. 2010 May 15;188(2):280-6. Epub 2010 Mar 15
Epub:
Not Epub
Abstract:
Gap junctions formed by expressing connexin subunits in Xenopus oocytes provide a valuable tool for revealing the gating...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hayar A, Charlesworth A, Garcia-Rill E. Oocyte triplet pairing for electrophysiological investigation of gap junctional coupling. J Neurosci Methods. 2010 May 15;188(2):280-6. Epub 2010 Mar 15.

Optical Pretargeting of Tumor with Fluorescent MORF Oligomers

Authors:
He J, Rusckowski M, Wang Y, Dou S, Liu X, Zhang S, Liu G, Hnatowich DJ
Citation:
Mol Imaging Biol. 2007 Jan-Feb;9(1):17-23.
Epub:
Not Epub
Abstract:
OBJECTIVE: <text omitted due to database length restrictions - Gene Tools> The use of linear fluorophore-conjugated...
Organism or Cell Type:
mice, SKH-1 hairless
Citation Extract:
He J, Rusckowski M, Wang Y, Dou S, Liu X, Zhang S, Liu G, Hnatowich DJ. Optical Pretargeting of Tumor with Fluorescent MORF Oligomers. Mol Imaging Biol. 2007 Jan-Feb;9(1):17-23..

Pharmacokinetics in mice of four oligomer-conjugated polymers for amplification targeting

Authors:
He J, Liu G, Zhang S, Rusckowski M, Hnatowich DJ
Citation:
Cancer Biother Radiopharm. 2003 Dec;18(6):941-7
Epub:
Not Epub
Abstract:
For use in amplification targeting, an oligomer-conjugated polymer must display adaptable chemistry, minimal steric hindrance,...
Delivery Method:
in vivo: injection
Organism or Cell Type:
mice, CD-1
Citation Extract:
He J, Liu G, Zhang S, Rusckowski M, Hnatowich DJ. Pharmacokinetics in mice of four oligomer-conjugated polymers for amplification targeting. Cancer Biother Radiopharm. 2003 Dec;18(6):941-7.

Planar cell polarization requires Widerborst, a B' regulatory subunit of protein phosphatase 2A

Authors:
Hannus M, Feiguin F, Heisenberg CP, Eaton S
Citation:
Development. 2002 Jul;129(14):3493-503
Epub:
Not Epub
Abstract:
We have identified widerborst (wdb), a B' regulatory subunit of PP2A, as a conserved component of planar cell polarization...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hannus M, Feiguin F, Heisenberg CP, Eaton S. Planar cell polarization requires Widerborst, a B' regulatory subunit of protein phosphatase 2A. Development. 2002 Jul;129(14):3493-503.

Podocin-green fluorescence protein allows visualization and functional analysis of podocytes

Authors:
He B, Ebarasi L, Hultenby K, Tryggvason K, Betsholtz C
Citation:
J Am Soc Nephrol. 2011 Jun;22(6):1019-23. Epub 2011 May 12
Epub:
Not Epub
Abstract:
Podocytes do not remain fully differentiated when cultured, and they are difficult to image in vivo, making the study of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
He B, Ebarasi L, Hultenby K, Tryggvason K, Betsholtz C. Podocin-green fluorescence protein allows visualization and functional analysis of podocytes. J Am Soc Nephrol. 2011 Jun;22(6):1019-23. Epub 2011 May 12.

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