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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
FBXW7β isoform drives transcriptional activation of a proinflammatory TNF cluster in normal and malignant pro-B cells
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.04.24.489313 Epub:
Not Epub Abstract:
Non-canonical exon usage plays many important roles in cellular phenotypes, but its contribution to human B-cell development... Delivery Method:
electroporation Organism or Cell Type:
cell culture: REH from B-Cell Acute Lymphoblastic Leukemia patients Citation Extract: Yang SY, Hayer KE, Fazelinia H, Asnani M, Black KL, Naqvi AS, Pillai V, Spruce LA, Barash Y, Elenitoba-Johnson KSJ, Thomas-Tikhonenko A. FBXW7β isoform drives transcriptional activation of a proinflammatory TNF cluster in normal and malignant pro-B cells. bioRxiv. 2022;[preprint] doi:10.1101/2022.04.24.489313. |
Probiotics Enhance Bone Growth and Rescue BMP Inhibition: New Transgenic Zebrafish Lines to Study Bone Health
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Citation:
Int J Mol Sci. 2022; 23(9):4748. doi:10.3390/ijms23094748 Epub:
Not Epub Abstract:
Zebrafish larvae, especially gene-specific mutants and transgenic lines, are increasingly used to study vertebrate skeletal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sojan JM, Raman R, Muller M, Carnevali O, Renn J. Probiotics Enhance Bone Growth and Rescue BMP Inhibition: New Transgenic Zebrafish Lines to Study Bone Health. Int J Mol Sci. 2022; 23(9):4748. doi:10.3390/ijms23094748. |
Granulocyte Colony-Stimulating Factor Mediated Regulation of Early Myeloid Cells in Zebrafish
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Citation:
Front Biosci (Landmark Ed). 2022 Mar 28;27(4):110. doi: 10.31083/j.fbl2704110 Epub:
Not Epub Abstract:
Background: Colony-stimulating factor 3 (CSF3), more commonly known as granulocyte colony-stimulating factor (G-CSF), acts via... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Meier AB, Basheer F, Sertori R, Laird M, Liongue C, Ward AC. Granulocyte Colony-Stimulating Factor Mediated Regulation of Early Myeloid Cells in Zebrafish. Front Biosci (Landmark Ed). 2022 Mar 28;27(4):110. doi: 10.31083/j.fbl2704110. |
Modulation of PKM1/2 levels by steric blocking morpholinos alters the metabolic and pluripotent state of murine pluripotent stem cells
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Citation:
Stem Cells Dev. 2022 Apr 25. doi: 10.1089/scd.2021.0347. Online ahead of print Epub:
Not Epub Abstract:
Cellular metabolism plays both an active and passive role in embryonic development, pluripotency, and cell-fate decisions.... Delivery Method:
cell culture: murine embryonic stem cells Citation Extract: Dierolf JG, Hunter HLM, Watson AJ, Betts DH. Modulation of PKM1/2 levels by steric blocking morpholinos alters the metabolic and pluripotent state of murine pluripotent stem cells. Stem Cells Dev. 2022 Apr 25. doi: 10.1089/scd.2021.0347. Online ahead of print. |
"Two-story building" of a ctenophore comb plate provides structural and functional integrity for motility of giant multicilia
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.03.27.486007 Epub:
Not Epub Abstract:
Comb plates (CPs) are large compound cilia uniquely seen in a basal metazoan group of ctenophores. Tens of thousands of cilia... Delivery Method:
microinjection Organism or Cell Type:
Bolinopsis mikado (ctenophore) Citation Extract: Jokura K, Sato Y, Shiba K, Inaba K. "Two-story building" of a ctenophore comb plate provides structural and functional integrity for motility of giant multicilia. bioRxiv. 2022;[preprint] doi:10.1101/2022.03.27.486007 . |
STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.11.19.469257 Epub:
Not Epub Abstract:
STAT3 and HIF1α are two fundamental transcription factors involved in many merging processes, like angiogenesis, metabolism,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dinarello A, Betto RM, Diamante L, Cioccarelli C, Meneghetti G, Peron M, Tesoriere A, Laquatra C, Tiso N, Martello G, Argenton F. STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia. bioRxiv. 2021;[preprint] doi:10.1101/2021.11.19.469257. |
Quality assurance of hematopoietic stem cells by macrophages determines stem cell clonality
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.03.07.483327 Epub:
Not Epub Abstract:
Tissue-specific stem cells persist for a lifetime and can differentiate to maintain homeostasis or transform to initiate cancer... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wattrus SJ, Smith ML, Rodrigues CP, Hagedorn EJ, Budnik B, Zon LI. Quality assurance of hematopoietic stem cells by macrophages determines stem cell clonality. bioRxiv. 2022;[preprint] doi:10.1101/2022.03.07.483327. |
Cell Clusters Containing Intestinal Stem Cells Line the Zebrafish Intestine Intervillus Pocket
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Citation:
iScience. 2022;104280 [Epub]. doi:10.1016/j.isci.2022.104280 Epub:
Yes Abstract:
In the mammalian intestine, stem cells (ISCs) replicate in basal crypts, translocate along the villus, and undergo cell death.... Delivery Method:
Vivo-Morphoino intestinal gavage Organism or Cell Type:
zebrafish Citation Extract: Tavakoli S, Zhu S, Matsudaira P. Cell Clusters Containing Intestinal Stem Cells Line the Zebrafish Intestine Intervillus Pocket. iScience. 2022;104280 [Epub]. doi:10.1016/j.isci.2022.104280. |
VDAC1 regulates neuronal cell loss after retinal trauma injury by a mitochondria-independent pathway
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Citation:
Cell Death Dis. 2022 Apr 21;13(4):393. doi: 10.1038/s41419-022-04755-3 Epub:
Not Epub Abstract:
The voltage-dependent anion channel 1 (VDAC1) was first described as a mitochondrial porin that mediates the flux of... Delivery Method:
subretinal injection Organism or Cell Type:
male and female Long Evans rats (Rattus norvegicus) Citation Extract: de Sousa E, Móvio MI, de Lima-Vasconcellos TH, Dos Santos GB, Dos Santos Gomes T, Walter LT, da Silva DA, Rodrigues T, Cerchiaro G, Kihara AH. VDAC1 regulates neuronal cell loss after retinal trauma injury by a mitochondria-independent pathway. Cell Death Dis. 2022 Apr 21;13(4):393. doi: 10.1038/s41419-022-04755-3. |
The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio
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Citation:
Proc Nat Acad Sci USA. 2022;117(17):e2112225119 [Epub] doi:10.1073/pnas.2112225119 Epub:
Not Epub Abstract:
Hypocretin (Hcrt), also known as orexin, neuropeptide signaling stabilizes sleep and wakefulness in all vertebrates. A lack of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Holm A, Possovre M-L, Bandarabadi M, Moseholm KF, Justinussen JL, Bozic I, Lemcke R, Arribat Y, Amati F, Silahtaroglu A, Juventin M, Adamantidis A, Tafti M, Kornum BR. The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio. Proc Nat Acad Sci USA. 2022;117(17):e2112225119 [Epub] doi:10.1073/pnas.2112225119. |