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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Collective durotaxis along a self-generated stiffness gradient in vivo
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Citation:
Nature. 2021;[Epub ahead of print]. doi:10.1038/s41586-021-04210-x Epub:
Not Epub Abstract:
Collective cell migration underlies morphogenesis, wound healing and cancer invasion. Most directed migration in vivo has been... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Shellard A, Mayor R. Collective durotaxis along a self-generated stiffness gradient in vivo. Nature. 2021;[Epub ahead of print]. doi:10.1038/s41586-021-04210-x. |
Mechanisms underlying microglial colonization of developing neural retina in zebrafish
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Citation:
eLife. 2021;10:e70550. doi:10.7554/eLife.70550 Epub:
Not Epub Abstract:
Microglia are brain-resident macrophages that function as the first line of defense in brain. Embryonic microglial precursors... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ranawat N, Masai I. Mechanisms underlying microglial colonization of developing neural retina in zebrafish. eLife. 2021;10:e70550. doi:10.7554/eLife.70550. |
Restoration of Normal NF1 Function with Antisense Morpholino Treatment of Recurrent Pathogenic Patient-Specific Variant c.1466A>G; p.Y489C
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Citation:
J Pers Med 2021;11(12):1320. doi:10.3390/jpm11121320 Epub:
Not Epub Abstract:
Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic disorder with almost 3000 different disease-causing variants... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: human PGP1 iPSC Citation Extract: Awad EK, Moore M, Liu H, Ciszewski L, Lambert L, Korf BR, Popplewell L, Kesterson RA, Wallis D. Restoration of Normal NF1 Function with Antisense Morpholino Treatment of Recurrent Pathogenic Patient-Specific Variant c.1466A>G; p.Y489C. J Pers Med 2021;11(12):1320. doi:10.3390/jpm11121320. |
Matriptase activation of Gq drives epithelial disruption and inflammation via RSK and DUOX
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Citation:
eLife 2021;10:e66596 doi: 10.7554/eLife.66596 Epub:
Not Epub Abstract:
Epithelial tissues are primed to respond to insults by activating epithelial cell motility and rapid inflammation. Such... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ma J, Scott CA, Ho YN, Mahabaleshwar H, Marsay KS, Zhang C, Teow CKJ, Ng SS, Zhang W. Matriptase activation of Gq drives epithelial disruption and inflammation via RSK and DUOX. eLife 2021;10:e66596 doi: 10.7554/eLife.66596. |
Tet enzymes are essential for early embryogenesis and completion of embryonic genome activation
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Citation:
EMBO Rep. 2021 Dec 6:e53968. doi: 10.15252/embr.202153968. Online ahead of print Epub:
Not Epub Abstract:
Mammalian development begins in transcriptional silence followed by a period of widespread activation of thousands of genes.... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Arand J, Chiang HR, Martin D, Snyder MP, Sage J, Reijo Pera RA, Wossidlo M. Tet enzymes are essential for early embryogenesis and completion of embryonic genome activation. EMBO Rep. 2021 Dec 6:e53968. doi: 10.15252/embr.202153968. Online ahead of print. |
Evaluation of endogenous miRNA reference genes across different zebrafish strains, developmental stages and kidney disease models
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Citation:
Sci Rep. 2021;11(1):22894. doi:10.1038/s41598-021-00075-2 Epub:
Not Epub Abstract:
The majority of kidney diseases arise from the loss of podocytes and from morphological changes of their highly complex foot... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Siegerist F, Lange T, Iervolino A, Koppe TM, Zhou W, Capasso G, Endlich K, Endlich N. Evaluation of endogenous miRNA reference genes across different zebrafish strains, developmental stages and kidney disease models. Sci Rep. 2021;11(1):22894. doi:10.1038/s41598-021-00075-2. |
RGS2 Suppresses Melanoma Growth via Inhibiting MAPK and AKT Signaling Pathways
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Citation:
Anticancer Res. 2021 Dec;41(12):6135-6145. doi: 10.21873/anticanres.15433 Epub:
Not Epub Abstract:
Background/Aim: This study aimed to explore RGS2 as a regulator of melanoma cell growth. Materials and Methods: Effect of RGS2... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin SJ, Huang YC, Chen HY, Fang JY, Hsu SY, Shih HY, Liu YC, Cheng YC. RGS2 Suppresses Melanoma Growth via Inhibiting MAPK and AKT Signaling Pathways. Anticancer Res. 2021 Dec;41(12):6135-6145. doi: 10.21873/anticanres.15433. |
A Dystrophin Exon-52 Deleted Miniature Pig Model of Duchenne Muscular Dystrophy and Evaluation of Exon Skipping
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Citation:
Int J Mol Sci. 2021;22(23):13065. doi:10.3390/ijms222313065 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a lethal X-linked recessive disorder caused by mutations in the DMD gene and the... Delivery Method:
peptide-linked, Endo-Porter Organism or Cell Type:
Sus scrofa domestica (pig) Citation Extract: Echigoya Y, Trieu N, Duddy W, Moulton HM, Yin H, Partridge TA, Hoffman EP, Kornegay JN, Rohret FA, Rogers CS, Yokota T. A Dystrophin Exon-52 Deleted Miniature Pig Model of Duchenne Muscular Dystrophy and Evaluation of Exon Skipping. Int J Mol Sci. 2021;22(23):13065. doi:10.3390/ijms222313065 . |
Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development
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Citation:
Blood Adv. 2021 Dec 14;5(23):4949-4962. doi: 10.1182/bloodadvances.2020003969 Epub:
Not Epub Abstract:
RUNX1 is essential for the generation of hematopoietic stem cells (HSCs). Runx1-null mouse embryos lack definitive... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bresciani E, Carrington B, Yu K, Kim EM, Zhen T, Guzman VS, Broadbridge E, Bishop K, Kirby M, Harper U, Wincovitch S, Dell'Orso S, Sartorelli V, Sood R, Liu P. Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development. Blood Adv. 2021 Dec 14;5(23):4949-4962. doi: 10.1182/bloodadvances.2020003969. |
Hapln1b, a central organizer of the ECM, modulates kit signaling to control developmental hematopoiesis in zebrafish
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Citation:
Blood Adv. 2021 Dec 14;5(23):4935-4948. doi: 10.1182/bloodadvances.2020001524 Epub:
Not Epub Abstract:
During early vertebrate development, hematopoietic stem and progenitor cells (HSPCs) are produced in hemogenic endothelium... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mahony CB, Cacialli P, Pasche C, Monteiro R, Savvides SN, Bertrand JY. Hapln1b, a central organizer of the ECM, modulates kit signaling to control developmental hematopoiesis in zebrafish. Blood Adv. 2021 Dec 14;5(23):4935-4948. doi: 10.1182/bloodadvances.2020001524. |