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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy
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Citation:
Cell Death Differ. 2019 Mar 1. doi: 10.1038/s41418-019-0311-z. [Epub ahead of print] Epub:
Yes Abstract:
TAMM41, located within the congenital heart diseases (CHD) sensitive region of 3p25 deletion syndrome, is a mitochondrial... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang RM, Tao J, Zhan M, Yuan H, Wang HH, Chen SJ, Zhu C, de Thé H, Zhou J, Guo Y, Zhu J. TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy. Cell Death Differ. 2019 Mar 1. doi: 10.1038/s41418-019-0311-z. [Epub ahead of print]. |
Exon-mediated activation of transcription starts
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/565184 Epub:
Not Epub Abstract:
The processing of transcripts from mammalian genes often occurs near in time and space to their transcription. Here we... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: mouse fibroblasts Citation Extract: Fiszbein A, Krick KS, Burge CB. Exon-mediated activation of transcription starts. bioRxiv. 2019;[preprint] doi:10.1101/565184. |
GRIK5 Genetically Regulated Expression Associated with Eye and Vascular Phenomes: Discovery through Iteration among Biobanks, Electronic Health Records, and Zebrafish
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Citation:
Am J Hum Genet. 2019 Feb 27. pii: S0002-9297(19)30017-5. doi: 10.1016/j.ajhg.2019.01.017. [Epub ahead of print] Epub:
Yes Abstract:
Although the use of model systems for studying the mechanism of mutations that have a large effect is common, we highlight here... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Unlu G, Gamazon ER, Qi X, Levic DS, Bastarache L, Denny JC, Roden DM, Mayzus I, Breyer M, Zhong X, Konkashbaev AI, Rzhetsky A, Knapik EW, Cox NJ. GRIK5 Genetically Regulated Expression Associated with Eye and Vascular Phenomes: Discovery through Iteration among Biobanks, Electronic Health Records, and Zebrafish. Am J Hum Genet. 2019 Feb 27. pii: S0002-9297(19)30017-5. doi: 10.1016/j.ajhg.2019.01.017. [Epub ahead of print]. |
Evolution of nitric oxide regulation of gut function
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Citation:
Proc Nat Acad Sci USA. 2019;[Epub ahead of print] doi:10.1073/pnas.1816973116 Epub:
Yes Abstract:
Although morphologies are diverse, the common pattern in bilaterians is for passage of food in the gut to be controlled by... Delivery Method:
microinjection Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin) Citation Extract: Yaguchi J, Yaguchi S. Evolution of nitric oxide regulation of gut function. Proc Nat Acad Sci USA. 2019;[Epub ahead of print] doi:10.1073/pnas.1816973116. |
The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection
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Citation:
PLoS Pathog. 2019;15(2):e1007329. doi:10.1371/journal.ppat.1007329 Epub:
Not Epub Abstract:
Mycobacterial pathogens are the causative agents of chronic infectious diseases like tuberculosis and leprosy. Autophagy has... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang R, Varela M, Vallentgoed W, Forn-Cuni G, van der Vaart M, Meijer AH. The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection. PLoS Pathog. 2019;15(2):e1007329. doi:10.1371/journal.ppat.1007329. |
Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain
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Citation:
Neural Dev. 2019;14:5. doi:10.1186/s13064-019-0129-x Epub:
Not Epub Abstract:
Background: Functioning of the adult nervous system depends on the establishment of neural circuits during embryogenesis. In... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yildiz O, Downes GB, Sagerström CG. Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain. Neural Dev. 2019;14:5. doi:10.1186/s13064-019-0129-x. |
Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependent pigment progenitors in zebrafish
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Citation:
PLoS Genet. 2019;15(2):e1007941. doi:10.1371/journal.pgen.1007941 Epub:
Not Epub Abstract:
Skin pigment patterns are important, being under strong selection for multiple roles including camouflage and UV protection.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Camargo-Sosa K, Colanesi S, Müller J, Schulte-Merker S, Stemple D, Patton EE, Kelsh RN
. Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependent pigment progenitors in zebrafish. PLoS Genet. 2019;15(2):e1007941. doi:10.1371/journal.pgen.1007941. |
Mutations in the Glycosyltransferase Domain of GLT8D1 Are Associated with Familial Amyotrophic Lateral Sclerosis
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Citation:
Cell Rep. 2019;26(9):2298-306. doi:10.1016/j.celrep.2019.02.006 Epub:
Not Epub Abstract:
Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disorder without effective neuroprotective therapy. Known... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cooper-Knock J, Moll T, Ramesh T, Castelli L, Beer A, Robins H, Fox I, Niedermoser I, Van Damme P, Moisse M, Robberecht W, Hardiman O, Panades MP, Assialioui A, Mora JS, Basak AN, Morrison KE, Shaw CE, Al-Chalabi A, Landers JE, Wyles M, Heath PR, Higginbottom A, Walsh T, Kazoka M, McDermott CJ, Hautbergue GM, Kirby J, Shaw PJ. Mutations in the Glycosyltransferase Domain of GLT8D1 Are Associated with Familial Amyotrophic Lateral Sclerosis. Cell Rep. 2019;26(9):2298-306. doi:10.1016/j.celrep.2019.02.006. |
A familial congenital heart disease with a possible multigenic origin involving a mutation in BMPR1A
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Citation:
Sci Rep. 2019;9:2959. doi:10.1038/s41598-019-39648-7 Epub:
Not Epub Abstract:
The genetics of many congenital heart diseases (CHDs) can only unsatisfactorily be explained by known chromosomal or Mendelian... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Demal TJ, Heise M, Reiz B, Dogra D, Brænne I, Reichenspurner H, Männer J, Aherrahrou Z, Schunkert H, Erdmann J, Abdelilah-Seyfried S. A familial congenital heart disease with a possible multigenic origin involving a mutation in BMPR1A. Sci Rep. 2019;9:2959. doi:10.1038/s41598-019-39648-7. |
Fluid dynamics during bleb formation in migrating cells in vivo
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Citation:
PLoS ONE. 2019;14(2): e0212699. doi:10.1371/journal.pone.0212699 Epub:
Not Epub Abstract:
Blebs are cellular protrusions observed in migrating cells and in cells undergoing spreading, cytokinesis, and apoptosis. Here... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Goudarzi M, Boquet-Pujadas A, Olivo-Marin J-C, Raz E. Fluid dynamics during bleb formation in migrating cells in vivo. PLoS ONE. 2019;14(2): e0212699. doi:10.1371/journal.pone.0212699. |