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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Intelectin 3 is dispensable for resistance against a mycobacterial infection in zebrafish (Danio rerio)
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Citation:
Sci Rep. 2019 Jan 30;9(1):995. doi: 10.1038/s41598-018-37678-1 Epub:
Not Epub Abstract:
Tuberculosis is a multifactorial bacterial disease, which can be modeled in the zebrafish (Danio rerio). Abdominal cavity... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ojanen MJT, Uusi-Mäkelä MIE, Harjula SE, Saralahti AK, Oksanen KE, Kähkönen N, Määttä JAE, Hytönen VP, Pesu M, Rämet M. Intelectin 3 is dispensable for resistance against a mycobacterial infection in zebrafish (Danio rerio). Sci Rep. 2019 Jan 30;9(1):995. doi: 10.1038/s41598-018-37678-1. |
Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport
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Citation:
Nat Commun. 2019 Jan 25;10(1):428. doi: 10.1038/s41467-018-08192-9 Epub:
Not Epub Abstract:
The intracellular ciliogenesis pathway requires membrane trafficking, fusion, and reorganization. Here, we demonstrate in human... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Insinna C, Lu Q, Teixeira I, Harned A, Semler EM, Stauffer J, Magidson V, Tiwari A, Kenworthy AK, Narayan K, Westlake CJ. Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport. Nat Commun. 2019 Jan 25;10(1):428. doi: 10.1038/s41467-018-08192-9. |
Venous identity requires BMP signalling through ALK3
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Citation:
Nat Comm. 2019;10:453. doi:doi.org/10.1038/s41467-019-08315-w Epub:
Not Epub Abstract:
Venous endothelial cells are molecularly and functionally distinct from their arterial counterparts. Although veins are often... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Neal A, Nornes S, Payne S, Wallace MD, Fritzsche M, Louphrasitthiphol P, Wilkinson RN, Chouliaras KM, Liu K, Plant K, Sholapurkar R, Ratnayaka I, Herzog W, Bond G, Chico T, Bou-Gharios G, De Val S. Venous identity requires BMP signalling through ALK3. Nat Comm. 2019;10:453. doi:doi.org/10.1038/s41467-019-08315-w. |
Scavenger receptor class A1 mediates uptake of morpholino antisense oligonucleotide into dystrophic skeletal muscle
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Citation:
Mol Ther Nucl Acids. 2019 Jan 25;14:520-535. doi: 10.1016/j.omtn.2019.01.008. Epub:
Not Epub Abstract:
Exon-skipping using phosphorodiamidate morpholino oligomers (PMOs) is a promising treatment strategy for Duchenne muscular... Delivery Method:
peptide-linked, cell bathing Organism or Cell Type:
mice mdx62, cell culture: H2K-mdx 52 myoblasts Citation Extract: Miyatake S, Mizobe Y, Tsoumpra M, Lim KRQ, Hara Y, Shabanpoor F, Yokota T, Takeda S, Aoki Y. Scavenger receptor class A1 mediates uptake of morpholino antisense oligonucleotide into dystrophic skeletal muscle. Mol Ther Nucl Acids. 2019 Jan 25;14:520-535. doi: 10.1016/j.omtn.2019.01.008. . |
Photoreceptor cell development requires prostaglandin signaling in the zebrafish retina
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Citation:
Biochem Biophys Res Commun. 2019 Jan 24. pii: S0006-291X(19)30087-7. doi: 10.1016/j.bbrc.2019.01.073. [Epub ahead of print] Epub:
Yes Abstract:
Photoreceptor cells are highly specialized sensory neurons capable of visual phototransduction. The connecting cilia in the... Organism or Cell Type:
zebrafish Citation Extract: Li W, Jin D, Zhong TP. Photoreceptor cell development requires prostaglandin signaling in the zebrafish retina. Biochem Biophys Res Commun. 2019 Jan 24. pii: S0006-291X(19)30087-7. doi: 10.1016/j.bbrc.2019.01.073. [Epub ahead of print]. |
Loss of foxc1 in zebrafish reduces optic nerve size and cell number in the ganglion cell layer
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Citation:
Vision Res. 2019 Jan 23. pii: S0042-6989(19)30020-3. doi: 10.1016/j.visres.2019.01.008. [Epub ahead of print] Epub:
Yes Abstract:
Mutation of FOXC1 causes Axenfeld-Rieger Syndrome (ARS) with early onset or congenital glaucoma. We assessed retinal ganglion... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Umali J, Hawkey-Noble A, French CR. Loss of foxc1 in zebrafish reduces optic nerve size and cell number in the ganglion cell layer. Vision Res. 2019 Jan 23. pii: S0042-6989(19)30020-3. doi: 10.1016/j.visres.2019.01.008. [Epub ahead of print]. |
A zebrafish model to study small-fiber neuropathy reveals a potential role for GDAP1
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Citation:
Mitochondrion. 2019;[Epub ahead of print] doi:10.1016/j.mito.2019.01.002 Epub:
Yes Abstract:
Mutations in genes involved in mitochondrial dynamics (fusion and fission) have been implicated in many peripheral neuropathies... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Eijkenboom I, Vanoevelen JM, Hoeijmakers JGJ, Wijnen I, Gerards M, Faber CG, Smeets HJM. A zebrafish model to study small-fiber neuropathy reveals a potential role for GDAP1. Mitochondrion. 2019;[Epub ahead of print] doi:10.1016/j.mito.2019.01.002. |
Mechanically activated Piezo channels control outflow tract valve development through Yap1 and Klf2-Notch signaling axis
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Citation:
bioRxiv. 2019;[Preprint] doi:10.1101/529016 Epub:
Not Epub Abstract:
Mechanical forces are well known for modulating heart valve developmental programs. Yet, it is still unclear how genetic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Duchemin AL, Vignes H, Vermot J. Mechanically activated Piezo channels control outflow tract valve development through Yap1 and Klf2-Notch signaling axis. bioRxiv. 2019;[Preprint] doi:10.1101/529016. |
Degradation of endogenous proteins and generation of a null-like phenotype in zebrafish using Trim-Away technology
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Citation:
Genome Bio. 2019;20:19. doi:10.1186/s13059-019-1624-4 Epub:
Not Epub Abstract:
Trim-Away is a recent technique to rapidly deplete a protein from any cell type. Guided by antibodies, TRIM21 selects proteins... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen X, Liu M, Lou H, Lu Y, Zhou M-T, Ou R, Xu Y, Kai-Fu Tang K-F. Degradation of endogenous proteins and generation of a null-like phenotype in zebrafish using Trim-Away technology. Genome Bio. 2019;20:19. doi:10.1186/s13059-019-1624-4. |
Lack of GAS2L2 Causes PCD by Impairing Cilia Orientation and Mucociliary Clearance
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Citation:
Am J Hum Genet. 2019 Jan 18. pii: S0002-9297(18)30460-9. doi: 10.1016/j.ajhg.2018.12.009. [Epub ahead of print] Epub:
Yes Abstract:
Primary ciliary dyskinesia (PCD) is a genetic disorder in which impaired ciliary function leads to chronic airway disease.... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Bustamante-Marin XM, Yin WN, Sears PR, Werner ME, Brotslaw EJ, Mitchell BJ, Jania CM, Zeman KL, Rogers TD, Herring LE, Refabért L, Thomas L, Amselem S, Escudier E, Legendre M, Grubb BR, Knowles MR, Zariwala MA, Ostrowski LE. Lack of GAS2L2 Causes PCD by Impairing Cilia Orientation and Mucociliary Clearance. Am J Hum Genet. 2019 Jan 18. pii: S0002-9297(18)30460-9. doi: 10.1016/j.ajhg.2018.12.009. [Epub ahead of print]. |