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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Distinct and redundant functions of Esam and VE-cadherin during vascular morphogenesis

Authors:
Sauteur L, Affolter M, Belting HG
Citation:
Development. 2017 Mar 6. pii: dev.140038. doi: 10.1242/dev.140038. [Epub ahead of print]
Epub:
Yes
Abstract:
The cardiovascular system forms during early embryogenesis and adapts to embryonic growth by sprouting angiogenesis and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sauteur L, Affolter M, Belting HG. Distinct and redundant functions of Esam and VE-cadherin during vascular morphogenesis. Development. 2017 Mar 6. pii: dev.140038. doi: 10.1242/dev.140038. [Epub ahead of print].

A systems level approach reveals new gene regulatory modules in the developing ear

Authors:
Chen J, Tambalo M, Barembaum M, Ranganathan R, Simões-Costa M, Bronner ME, Streit A
Citation:
Development. 2017 Mar 6. pii: dev.148494. doi: 10.1242/dev.148494. [Epub ahead of print]
Epub:
Yes
Abstract:
The inner ear is a complex vertebrate sense organ, yet arises from a simple epithelium, the otic placode. Specification towards...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Chen J, Tambalo M, Barembaum M, Ranganathan R, Simões-Costa M, Bronner ME, Streit A. A systems level approach reveals new gene regulatory modules in the developing ear. Development. 2017 Mar 6. pii: dev.148494. doi: 10.1242/dev.148494. [Epub ahead of print].

Xenopus Vasa Homolog XVLG1 is Essential for Migration and Survival of Primordial Germ Cells

Authors:
Shimaoka K, Mukumoto Y, Tanigawa Y, Komiya T
Citation:
Zoolog Sci. 2017 Apr;34(2):93-104. doi: 10.2108/zs160198
Epub:
Not Epub
Abstract:
Xenopus vasa-like gene 1 (XVLG1), a DEAD-Box Helicase 4 (DDX4) gene identified as a vertebrate vasa homologue, is required for...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Shimaoka K, Mukumoto Y, Tanigawa Y, Komiya T. Xenopus Vasa Homolog XVLG1 is Essential for Migration and Survival of Primordial Germ Cells. Zoolog Sci. 2017 Apr;34(2):93-104. doi: 10.2108/zs160198.

A Novel Perivascular Cell Population in the Zebrafish Brain

Authors:
Galanternik MV, Castranova D, Gore AV, Blewett NH, Jung HM, Stratman AN, Kirby MR, Iben J, Miller MF, Kawakami K, Maraia RJ, Weinstein BM
Citation:
eLife. 2017;10.7554/eLife.24369 doi:10.7554/eLife.24369
Epub:
Not Epub
Abstract:
The blood-brain barrier is essential for the proper homeostasis and function of the CNS, but its mechanism of function is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Galanternik MV, Castranova D, Gore AV, Blewett NH, Jung HM, Stratman AN, Kirby MR, Iben J, Miller MF, Kawakami K, Maraia RJ, Weinstein BM. A Novel Perivascular Cell Population in the Zebrafish Brain. eLife. 2017;10.7554/eLife.24369 doi:10.7554/eLife.24369.

Whole-Exome Sequencing of Congenital Glaucoma Patients Reveals Hypermorphic Variants in GPATCH3, a New Gene Involved in Ocular and Craniofacial Development

Authors:
Ferre-Fernández J-J, Aroca-Aguilar J-D, Medina-Trillo C, Bonet-Fernández J-M, Méndez-Hernández C-D, Morales-Fernández L, Corton M, Cabañero-Valera M-J, Gut M, Tonda R, Ayuso C, Coca-Prados M, García-Feijoo J, Escribano J
Citation:
Sci Rep. 2017;7:46175 doi:10.1038/srep46175
Epub:
Not Epub
Abstract:
Congenital glaucoma (CG) is a heterogeneous, inherited and severe optical neuropathy that originates from maldevelopment of the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ferre-Fernández J-J, Aroca-Aguilar J-D, Medina-Trillo C, Bonet-Fernández J-M, Méndez-Hernández C-D, Morales-Fernández L, Corton M, Cabañero-Valera M-J, Gut M, Tonda R, Ayuso C, Coca-Prados M, García-Feijoo J, Escribano J. Whole-Exome Sequencing of Congenital Glaucoma Patients Reveals Hypermorphic Variants in GPATCH3, a New Gene Involved in Ocular and Craniofacial Development. Sci Rep. 2017;7:46175 doi:10.1038/srep46175.

A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC)

Authors:
Sandoval IT, Delacruz RGC, Miller BN, Hill S, Olson KA, Gabriel AE, Boyd K, Satterfield C, Van Remmen H, Rutter J, Jones DA
Citation:
eLife. 2017;6:e22706. doi:10.7554/eLife.22706
Epub:
Not Epub
Abstract:
Elucidating signaling pathways that regulate cellular metabolism is essential for a better understanding of normal development...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sandoval IT, Delacruz RGC, Miller BN, Hill S, Olson KA, Gabriel AE, Boyd K, Satterfield C, Van Remmen H, Rutter J, Jones DA. A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC). eLife. 2017;6:e22706. doi:10.7554/eLife.22706.

TNFa/TNFR2 signaling is required for glial ensheathment at the dorsal root entry zone

Authors:
Smith CJ, Wheeler MA, Marjoram L, Bagnat M, Deppmann CD, Kucenas S
Citation:
PLoS Genet. 2017 Apr 5;13(4):e1006712. doi: 10.1371/journal.pgen.1006712. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Somatosensory information from the periphery is routed to the spinal cord through centrally-projecting sensory axons that cross...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Smith CJ, Wheeler MA, Marjoram L, Bagnat M, Deppmann CD, Kucenas S. TNFa/TNFR2 signaling is required for glial ensheathment at the dorsal root entry zone. PLoS Genet. 2017 Apr 5;13(4):e1006712. doi: 10.1371/journal.pgen.1006712. [Epub ahead of print].

The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger

Authors:
Keightley MC, Carradice DP, Layton JE, Pase L, Bertrand JY, Wittig JG, Dakic A, Badrock AP, Cole NJ, Traver D, Nutt SL, McCoey J, Buckle AM, Heath JK, Lieschke GJ
Citation:
Nat Commun. 2017 Apr 6;8:14911. doi: 10.1038/ncomms14911
Epub:
Not Epub
Abstract:
In response to infection and injury, the neutrophil population rapidly expands and then quickly re-establishes the basal state...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Keightley MC, Carradice DP, Layton JE, Pase L, Bertrand JY, Wittig JG, Dakic A, Badrock AP, Cole NJ, Traver D, Nutt SL, McCoey J, Buckle AM, Heath JK, Lieschke GJ. The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger. Nat Commun. 2017 Apr 6;8:14911. doi: 10.1038/ncomms14911.

Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes

Authors:
Witzel M, Petersheim D, Fan Y, Bahrami E, Racek T, Rohlfs M, Puchałka J, Mertes C, Gagneur J, Ziegenhain C, Enard W, Stray-Pedersen A, Arkwright PD, Abboud MR, Pazhakh V, Lieschke GJ, Krawitz PM, Dahlhoff M, Schneider MR, Wolf E, Horny HP, Schmidt H, Schäffer AA, Klein C
Citation:
Nat Genet. 2017 Apr 3. doi: 10.1038/ng.3833. [Epub ahead of print]
Epub:
Yes
Abstract:
We identify SMARCD2 (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily D, member 2), also...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Witzel M, Petersheim D, Fan Y, Bahrami E, Racek T, Rohlfs M, Puchałka J, Mertes C, Gagneur J, Ziegenhain C, Enard W, Stray-Pedersen A, Arkwright PD, Abboud MR, Pazhakh V, Lieschke GJ, Krawitz PM, Dahlhoff M, Schneider MR, Wolf E, Horny HP, Schmidt H, Schäffer AA, Klein C. Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes. Nat Genet. 2017 Apr 3. doi: 10.1038/ng.3833. [Epub ahead of print].

Concerted action of neuroepithelial basal shrinkage and active epithelial migration ensures efficient optic cup morphogenesis

Authors:
Sidhaye J, Norden C
Citation:
Elife. 2017 Apr 4;6. pii: e22689. doi: 10.7554/eLife.22689
Epub:
Not Epub
Abstract:
Organ formation is a multi-scale event that involves changes at the intracellular, cellular and tissue level. Organogenesis...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sidhaye J, Norden C. Concerted action of neuroepithelial basal shrinkage and active epithelial migration ensures efficient optic cup morphogenesis. Elife. 2017 Apr 4;6. pii: e22689. doi: 10.7554/eLife.22689.

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