You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Early frameshift alleles of zebrafish tbx5a that fail to develop the heartstrings phenotype
|
Citation:
bioRxiv. 2017. doi:10.1101/103168 Epub:
Not Epub Abstract:
Tbx5 is a key transcription factor for vertebrate heart and forelimb development that causes Holt-Oram syndrome when mutated in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chiavacci E, Kirchgeorg L, Felker A, Burger A, Mosimann C. Early frameshift alleles of zebrafish tbx5a that fail to develop the heartstrings phenotype. bioRxiv. 2017. doi:10.1101/103168. |
Genetic Drivers of Kidney Defects in the DiGeorge Syndrome
|
Citation:
N Engl J Med. 2017 Jan 25. doi: 10.1056/NEJMoa1609009. [Epub ahead of print] Epub:
Yes Abstract:
Background The DiGeorge syndrome, the most common of the microdeletion syndromes, affects multiple organs, including the heart... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lopez-Rivera E, Liu YP, Verbitsky M, Anderson BR, Capone VP, Otto EA, Yan Z, Mitrotti A, Martino J, Steers NJ, Fasel DA, Vukojevic K, Deng R, Racedo SE, Liu Q, Werth M, Westland R, Vivante A, Makar GS, Bodria M, Sampson MG, Gillies CE, Vega-Warner V, Maiorana M, Petrey DS, Honig B, Lozanovski VJ, Salomon R, Heidet L, Carpentier W, Gaillard D, Carrea A, Gesualdo L, Cusi D, Izzi C, Scolari F, van Wijk JA, Arapovic A, Saraga-Babic M, Saraga M, Kunac N, Samii A, McDonald-McGinn DM, Crowley TB, Zackai EH, Drozdz D, Miklaszewska M, Tkaczyk M, Sikora P, Szczepanska M, Mizerska-Wasiak M, <authors deleted - database limit> Tasic V, Latos-Bielenska A, Materna-Kiryluk A, Allegri L, Wong CS, Drummond IA, D'Agati V, Imamoto A, Barasch JM, Hildebrandt F, Kiryluk K, Lifton RP, Morrow BE, Jeanpierre C, Papaioannou VE, Ghiggeri GM, Gharavi AG, Katsanis N, Sanna-Cherchi S. Genetic Drivers of Kidney Defects in the DiGeorge Syndrome. N Engl J Med. 2017 Jan 25. doi: 10.1056/NEJMoa1609009. [Epub ahead of print]. |
Smc1β is required for activation of SAC during mouse oocyte meiosis
|
Citation:
Cell Cycle. 2017 Jan 24:0. doi: 10.1080/15384101.2017.1282583. [Epub ahead of print] Epub:
Yes Abstract:
Smc1β is a meiosis-specific cohesin subunit that is essential for sister chromatid cohesion and DNA recombination. Previous... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Miao Y, Zhou C, Cui Z, Dai X, Zhang M, Lu Y, Xiong B. Smc1β is required for activation of SAC during mouse oocyte meiosis. Cell Cycle. 2017 Jan 24:0. doi: 10.1080/15384101.2017.1282583. [Epub ahead of print]. |
Identification of a Peptide for Systemic Brain Delivery of a Morpholino Oligonucleotide in Mouse Models of Spinal Muscular Atrophy
|
Citation:
Nucleic Acid Ther. 2017 Jan 24. doi: 10.1089/nat.2016.0652. [Epub ahead of print] Epub:
Yes Abstract:
Splice-switching antisense oligonucleotides are emerging treatments for neuromuscular diseases, with several splice-switching... Delivery Method:
peptide-linked Organism or Cell Type:
mouse Citation Extract: Shabanpoor F, Hammond SM, Abendroth F, Hazell G, Wood MJ, Gait MJ. Identification of a Peptide for Systemic Brain Delivery of a Morpholino Oligonucleotide in Mouse Models of Spinal Muscular Atrophy. Nucleic Acid Ther. 2017 Jan 24. doi: 10.1089/nat.2016.0652. [Epub ahead of print]. |
FGF8/17/18 functions together with FGF9/16/20 during formation of the notochord in Ciona embryos
|
Citation:
Dev Biol. 2007 Feb 1;302(1):92-103 Epub:
Not Epub Abstract:
Fibroblast growth factor (FGF) signalling has been implicated in the generation of mesoderm and neural fates in chordate... Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis (ascidian) Citation Extract: Yasuo H, Hudson C. FGF8/17/18 functions together with FGF9/16/20 during formation of the notochord in Ciona embryos. Dev Biol. 2007 Feb 1;302(1):92-103. |
Isl2b regulates anterior second heart field development in zebrafish
|
Citation:
Sci Rep. 2017 Jan 20;7:41043. doi: 10.1038/srep41043 Epub:
Not Epub Abstract:
After initial formation, the heart tube grows by addition of second heart field progenitor cells to its poles. The... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Witzel HR, Cheedipudi S, Gao R, Stainier DY, Dobreva GD. Isl2b regulates anterior second heart field development in zebrafish. Sci Rep. 2017 Jan 20;7:41043. doi: 10.1038/srep41043. |
Excessive activation of ionotropic glutamate receptors induces apoptotic hair-cell death independent of afferent and efferent innervation
|
Citation:
Sci Rep. 2017 Jan 23;7:41102. doi: 10.1038/srep41102 Epub:
Not Epub Abstract:
Accumulation of excess glutamate plays a central role in eliciting the pathological events that follow intensely loud noise... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sheets L
. Excessive activation of ionotropic glutamate receptors induces apoptotic hair-cell death independent of afferent and efferent innervation. Sci Rep. 2017 Jan 23;7:41102. doi: 10.1038/srep41102. |
Suppression of Neu1 sialidase delays the absorption of yolk sac in medaka (Oryzias latipes) accompanied with the accumulation of α2-3 sialo-glycoproteins
|
Citation:
Biochimie. 2017 Jan 19. pii: S0300-9084(17)30013-5. doi: 10.1016/j.biochi.2017.01.008. [Epub ahead of print] Epub:
Yes Abstract:
Sialidase catalyzes the removal of sialic acids from glycoconjugates. Recently, medaka sialidase Neu1 has been cloned and its... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Ryuzono S, Takase R, Kamada Y, Ikenaga T, Chigwechokha PK, Komatsu M, Shiozaki K. Suppression of Neu1 sialidase delays the absorption of yolk sac in medaka (Oryzias latipes) accompanied with the accumulation of α2-3 sialo-glycoproteins. Biochimie. 2017 Jan 19. pii: S0300-9084(17)30013-5. doi: 10.1016/j.biochi.2017.01.008. [Epub ahead of print]. |
Rfx2 Stabilizes Foxj1 Binding at Chromatin Loops to Enable Multiciliated Cell Gene Expression
|
Citation:
PLoS Genet. 2017 Jan 19;13(1):e1006538. doi: 10.1371/journal.pgen.1006538 Epub:
Not Epub Abstract:
Cooperative transcription factor binding at cis-regulatory sites in the genome drives robust eukaryotic gene expression, and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Quigley IK, Kintner C. Rfx2 Stabilizes Foxj1 Binding at Chromatin Loops to Enable Multiciliated Cell Gene Expression. PLoS Genet. 2017 Jan 19;13(1):e1006538. doi: 10.1371/journal.pgen.1006538. |
Platelet-derived growth factor (PDGF) signaling directs cardiomyocyte movement toward the midline during heart tube assembly
|
Citation:
Elife. 2017 Jan 18;6. pii: e21172. doi: 10.7554/eLife.21172. [Epub ahead of print] Epub:
Yes Abstract:
Communication between neighboring tissues plays a central role in guiding organ morphogenesis. During heart tube assembly,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bloomekatz J, Singh R, Prall OW, Dunn AC, Vaughan M, Loo CS, Harvey RP, Yelon D. Platelet-derived growth factor (PDGF) signaling directs cardiomyocyte movement toward the midline during heart tube assembly. Elife. 2017 Jan 18;6. pii: e21172. doi: 10.7554/eLife.21172. [Epub ahead of print]. |