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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy
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Citation:
PLoS Biol. 2016 Sep 15;14(9):e1002552. doi: 10.1371/journal.pbio.1002552. eCollection 2016 Sep Epub:
Not Epub Abstract:
The lack of effective and well-tolerated therapies against antibiotic-resistant bacteria is a global public health problem... Delivery Method:
Peptide-linked Organism or Cell Type:
cell culture: Escherichia coli, Klebsiella pneumoniae, Salmonella enterica, Acinetobacter baumannii, Pseudomonas aeruginosa, Burkholderia cenocepacia Citation Extract: Ayhan DH, Tamer YT, Akbar M, Bailey SM, Wong M, Daly SM, Greenberg DE, Toprak E. Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy. PLoS Biol. 2016 Sep 15;14(9):e1002552. doi: 10.1371/journal.pbio.1002552. eCollection 2016 Sep. |
From Cryptic Toward Canonical Pre-mRNA Splicing in Pompe Disease: a Pipeline for the Development of Antisense Oligonucleotides
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Citation:
Mol Ther Nucleic Acids. 2016 Sep 13;5(9):e361. doi: 10.1038/mtna.2016.75 Epub:
Not Epub Abstract:
While 9% of human pathogenic variants have an established effect on pre-mRNA splicing, it is suspected that an additional 20%... Organism or Cell Type:
human primary fibroblasts Citation Extract: Bergsma AJ, In 't Groen SL, Verheijen FW, van der Ploeg AT, Pijnappel WP. From Cryptic Toward Canonical Pre-mRNA Splicing in Pompe Disease: a Pipeline for the Development of Antisense Oligonucleotides. Mol Ther Nucleic Acids. 2016 Sep 13;5(9):e361. doi: 10.1038/mtna.2016.75. |
NSrp70 is significant for embryonic growth and development, being a crucial factor for gastrulation and mesoderm induction
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Citation:
Biochem Biophys Res Commun. 2016 Sep 13. pii: S0006-291X(16)31502-9. doi: 10.1016/j.bbrc.2016.09.051. [Epub ahead of print] Epub:
Yes Abstract:
NSrp70 (nuclear speckle-related protein 70), a recently discovered protein and it belongs to the serine/arginine (SR) rich... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Lee SH, Kim C, Lee HK, Kim YK, Ismail T, Jeong Y, Park K, Park MJ, Park DS, Lee HS. NSrp70 is significant for embryonic growth and development, being a crucial factor for gastrulation and mesoderm induction. Biochem Biophys Res Commun. 2016 Sep 13. pii: S0006-291X(16)31502-9. doi: 10.1016/j.bbrc.2016.09.051. [Epub ahead of print]. |
Evi1 regulates Notch activation to induce zebrafish hematopoietic stem cell emergence
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Citation:
EMBO J. 2016 Sep 16. pii: e201593454. [Epub ahead of print] Epub:
Yes Abstract:
During development, hematopoietic stem cells (HSCs) emerge from aortic endothelial cells (ECs) through an intermediate stage... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Konantz M, Alghisi E, Müller JS, Lenard A, Esain V, Carroll KJ, Kanz L, North TE, Lengerke C. Evi1 regulates Notch activation to induce zebrafish hematopoietic stem cell emergence. EMBO J. 2016 Sep 16. pii: e201593454. [Epub ahead of print]. |
Mechanistic evaluation of benzo[a]pyrene's developmental toxicities mediated by reduced Cyp19a1b activity
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Citation:
Toxicol Sci. 2016 Sep 14. pii: kfw182. [Epub ahead of print] Epub:
Yes Abstract:
Benzo[a]pyrene (BaP) is a ubiquitous environmental contaminant that is both an endocrine disruptor and a carcinogen. Aromatase... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Alharthy KM, Albaqami FF, Thornton C, Corrales J, Willett KL. Mechanistic evaluation of benzo[a]pyrene's developmental toxicities mediated by reduced Cyp19a1b activity. Toxicol Sci. 2016 Sep 14. pii: kfw182. [Epub ahead of print]. |
Internal Oligoguanidinium-based Cellular Transporter Enhances Antisense Efficacy of Morpholinos in in vitro and Zebrafish model
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Citation:
Bioconjug Chem. 2016 Sep 14. [Epub ahead of print] Epub:
Yes Abstract:
Efficient cellular transporter is highly desirable for the therapeutic applications of antisense phosphorodiamidate morpholino... Organism or Cell Type:
zebrafish Citation Extract: Bhadra J, Pattanayak S, Khan PP, Kundu J, Sinha S. Internal Oligoguanidinium-based Cellular Transporter Enhances Antisense Efficacy of Morpholinos in in vitro and Zebrafish model. Bioconjug Chem. 2016 Sep 14. [Epub ahead of print]. |
Important role of endocannabinoid signaling in the development of functional vision and locomotion in zebrafish
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Citation:
FASEB J. 2016 Sep 13. pii: fj.201600602R. [Epub ahead of print] Epub:
Yes Abstract:
The developmental role of the endocannabinoid system still remains to be fully understood. Here, we report the presence of a... Organism or Cell Type:
zebrafish Citation Extract: Martella A, Sepe RM, Silvestri C, Zang J, Fasano G, Carnevali O, De Girolamo P, Neuhauss SC, Sordino P, Di Marzo V. Important role of endocannabinoid signaling in the development of functional vision and locomotion in zebrafish. FASEB J. 2016 Sep 13. pii: fj.201600602R. [Epub ahead of print]. |
Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy
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Citation:
Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):10962-7. doi: 10.1073/pnas.1605731113. Epub 2016 Sep 12 Epub:
Yes Abstract:
The development of antisense oligonucleotide therapy is an important advance in the identification of corrective therapy for... Delivery Method:
peptide-linked Organism or Cell Type:
mice Citation Extract: Hammond SM, Hazell G, Shabanpoor F, Saleh AF, Bowerman M, Sleigh JN, Meijboom KE, Zhou H, Muntoni F, Talbot K, Gait MJ, Wood MJ. Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):10962-7. doi: 10.1073/pnas.1605731113. Epub 2016 Sep 12. |
β-Catenin signaling positively regulates glutamate uptake and metabolism in astrocytes
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Citation:
J Neuroinflammation. 2016 Sep 10;13(1):242 Epub:
Not Epub Abstract:
BACKGROUND: Neurological disorders have been linked to abnormal excitatory neurotransmission. Perturbations in glutamate... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Lutgen V, Narasipura SD, Sharma A, Min S, Al-Harthi L. β-Catenin signaling positively regulates glutamate uptake and metabolism in astrocytes. J Neuroinflammation. 2016 Sep 10;13(1):242. |
Combining Zebrafish and Mouse Models to Test the Function of Deubiquitinating Enzyme (Dubs) Genes in Development: Role of USP45 in the Retina
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Citation:
Methods Mol Biol. 2016;1449:85-101. doi: 10.1007/978-1-4939-3756-1_3 Epub:
Not Epub Abstract:
Ubiquitination is a dynamic and reversible posttranslational modification. Much effort has been devoted to characterize the... Organism or Cell Type:
zebrafish Citation Extract: Toulis V, Garanto A, Marfany G. Combining Zebrafish and Mouse Models to Test the Function of Deubiquitinating Enzyme (Dubs) Genes in Development: Role of USP45 in the Retina. Methods Mol Biol. 2016;1449:85-101. doi: 10.1007/978-1-4939-3756-1_3. |