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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Nkx6 genes pattern the frog neural plate and Nkx6.1 is necessary for motoneuron axon projection

Authors:
Dichmann DS, Harland RM
Citation:
Dev Biol. 2010 Oct 27. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Neuronal subtypes originate from an undifferentiated neural epithelium that is progressively divided into progenitor domains by...
Delivery Method:
Microinjection
Organism or Cell Type:
X.laevis & X.tropicalis
Citation Extract:
Dichmann DS, Harland RM. Nkx6 genes pattern the frog neural plate and Nkx6.1 is necessary for motoneuron axon projection. Dev Biol. 2010 Oct 27. [Epub ahead of print].

Nodal and BMP2/4 pattern the mesoderm and endoderm during development of the sea urchin embryo

Authors:
Duboc V, Lapraz F, Saudemont A, Bessodes N, Mekpoh F, Haillot E, Quirin M, Lepage T
Citation:
Development. 2010 Jan;137(2):223-35
Epub:
Not Epub
Abstract:
Nodal factors play fundamental roles in induction and patterning of the mesoderm and endoderm in vertebrates, but whether this...
Delivery Method:
Microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Duboc V, Lapraz F, Saudemont A, Bessodes N, Mekpoh F, Haillot E, Quirin M, Lepage T. Nodal and BMP2/4 pattern the mesoderm and endoderm during development of the sea urchin embryo. Development. 2010 Jan;137(2):223-35.

Nodal and BMP2/4 Signaling Organizes the Oral-Aboral Axis of the Sea Urchin Embryo

Authors:
Duboc V, Rottinger E, Besnardeau L, Lepage T
Citation:
Dev Cell. 2004 Mar;6(3):397-410
Epub:
Not Epub
Abstract:
In the sea urchin embryo, the oral-aboral axis is specified after fertilization by mechanisms that are largely unknown. We...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus
Citation Extract:
Duboc V, Rottinger E, Besnardeau L, Lepage T. Nodal and BMP2/4 Signaling Organizes the Oral-Aboral Axis of the Sea Urchin Embryo. Dev Cell. 2004 Mar;6(3):397-410.

On the embryonic origin of adult melanophores: the role of ErbB and Kit signalling in establishing melanophore stem cells in zebrafish

Authors:
Dooley CM, Mongera A, Walderich B, Nüsslein-Volhard C
Citation:
Development. 2013 Jan 30. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Pigment cells in vertebrates are derived from the neural crest (NC), a pluripotent and migratory embryonic cell population. In...
Organism or Cell Type:
zebrafish
Citation Extract:
Dooley CM, Mongera A, Walderich B, Nüsslein-Volhard C. On the embryonic origin of adult melanophores: the role of ErbB and Kit signalling in establishing melanophore stem cells in zebrafish. Development. 2013 Jan 30. [Epub ahead of print].

p90Rsk is not involved in cytostatic factor arrest in mouse oocytes

Authors:
Dumont J, Umbhauer M, Rassinier P, Hanauer A, Verlhac MH
Citation:
J Cell Biol. 2005 Apr 25;169(2):227-31. Epub 2005 Apr 18.
Epub:
Not Epub
Abstract:
Vertebrate oocytes arrest in metaphase of the second meiotic division (MII), where they maintain a high cdc2/cyclin B activity...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Dumont J, Umbhauer M, Rassinier P, Hanauer A, Verlhac MH. p90Rsk is not involved in cytostatic factor arrest in mouse oocytes. J Cell Biol. 2005 Apr 25;169(2):227-31. Epub 2005 Apr 18..

Pax4 is not essential for beta-cell differentiation in zebrafish embryos but modulates alpha-cell generation by repressing arx gene expression

Authors:
Djiotsa J, Verbruggen V, Giacomotto J, Ishibashi M, Manning E, Rinkwitz S, Manfroid I, LVoz M, Peers B
Citation:
BMC Dev Biol. 2012;12:37 doi:10.1186/1471-213X-12-37
Epub:
Not Epub
Abstract:
Background Genetic studies in mouse have demonstrated the crucial function of PAX4 in pancreatic cell differentiation. This...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Djiotsa J, Verbruggen V, Giacomotto J, Ishibashi M, Manning E, Rinkwitz S, Manfroid I, LVoz M, Peers B. Pax4 is not essential for beta-cell differentiation in zebrafish embryos but modulates alpha-cell generation by repressing arx gene expression. BMC Dev Biol. 2012;12:37 doi:10.1186/1471-213X-12-37.

pitx3 defines an equivalence domain for lens and anterior pituitary placode

Authors:
Dutta S, Dietrich JE, Aspöck G, Burdine RD, Schier A, Westerfield M, Varga ZM
Citation:
Development. 2005 Apr;132(7):1579-90. Epub 2005 Feb 23
Epub:
Not Epub
Abstract:
Hedgehog signaling is required for formation and patterning of the anterior pituitary gland. However, the role of Hedgehog in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dutta S, Dietrich JE, Aspöck G, Burdine RD, Schier A, Westerfield M, Varga ZM. pitx3 defines an equivalence domain for lens and anterior pituitary placode. Development. 2005 Apr;132(7):1579-90. Epub 2005 Feb 23.

Positional cloning of 'Lisch-Like', a candidate modifier of susceptibility to type 2 diabetes in mice

Authors:
Dokmanovic-Chouinard M, Chung WK, Chevre JC, Watson E, Yonan J, Wiegand B, Bromberg Y, Wakae N, Wright CV, Overton J, Ghosh S, Sathe GM, Ammala CE, Brown KK, Ito R, LeDuc C, Solomon K, Fischer SG, Leibel RL
Citation:
PLoS Genet. 2008 Jul 25;4(7):e1000137
Epub:
Not Epub
Abstract:
In 404 Lep(ob/ob) F2 progeny of a C57BL/6J (B6) x DBA/2J (DBA) intercross, we mapped a DBA-related quantitative trait locus (...
Organism or Cell Type:
zebrafish
Citation Extract:
Dokmanovic-Chouinard M, Chung WK, Chevre JC, Watson E, Yonan J, Wiegand B, Bromberg Y, Wakae N, Wright CV, Overton J, Ghosh S, Sathe GM, Ammala CE, Brown KK, Ito R, LeDuc C, Solomon K, Fischer SG, Leibel RL. Positional cloning of 'Lisch-Like', a candidate modifier of susceptibility to type 2 diabetes in mice. PLoS Genet. 2008 Jul 25;4(7):e1000137.

Potential therapeutic applications of antisense morpholino oligonucleotides in modulation of splicing in primary immunodeficiency diseases

Authors:
Du L, Gatti RA
Citation:
J Immunol Methods. 2010 Dec 10. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Highly complementary antisense morpholino oligonucleotides (AMOs) can bind to pre-mRNA and modulate splicing site selection....
Citation Extract:
Du L, Gatti RA. Potential therapeutic applications of antisense morpholino oligonucleotides in modulation of splicing in primary immunodeficiency diseases. J Immunol Methods. 2010 Dec 10. [Epub ahead of print].

Presenilin Deficiency or Lysosomal Inhibition Enhances Wnt Signaling through Relocalization of GSK3 to the Late-Endosomal Compartment

Authors:
Dobrowolski R, Vick P, Ploper D, Gumper I, Snitkin H, Sabatini DD, De Robertis EM
Citation:
Cell Reports. 2012;[Epub ahead of print] doi:10.1016/j.celrep.2012.09.026
Epub:
Not Epub
Abstract:
Sustained canonical Wnt signaling requires the inhibition of glycogen synthase kinase 3 (GSK3) activity by sequestration of...
Organism or Cell Type:
Xenopus
Citation Extract:
Dobrowolski R, Vick P, Ploper D, Gumper I, Snitkin H, Sabatini DD, De Robertis EM. Presenilin Deficiency or Lysosomal Inhibition Enhances Wnt Signaling through Relocalization of GSK3 to the Late-Endosomal Compartment. Cell Reports. 2012;[Epub ahead of print] doi:10.1016/j.celrep.2012.09.026.

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