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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Coagulation Factor IIIa (f3a) Knockdown in Zebrafish Leads to Defective Angiogenesis and Mild Bleeding Phenotype

Authors:
Subramaniam S, Liu J, Fletcher C, Ramchandran R, Weiler H
Citation:
Front Cell Dev Biol. 10:852989. doi:10.3389/fcell.2022.852989
Epub:
Not Epub
Abstract:
Tissue factor (TF) is crucial for embryogenesis, as mice lacking TF are embryonically lethal (E10.5). This lethality may be...
Link:
https://www.frontiersin.org/articles/10.3389/fcell.2022.852989/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Subramaniam S, Liu J, Fletcher C, Ramchandran R, Weiler H. Coagulation Factor IIIa (f3a) Knockdown in Zebrafish Leads to Defective Angiogenesis and Mild Bleeding Phenotype. Front Cell Dev Biol. 10:852989. doi:10.3389/fcell.2022.852989.

Exonization by the Emergence of a Cleavage-Polyadenylation Site

Authors:
Méreau A, Lerivray H, Viet J, Hardy S, Paillard L, Audic Y
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.03.17.484714
Epub:
Not Epub
Abstract:
Exonization is the evolutionary process of recruitment of new exonic regions from previously intronic regions. It is a major...
Link:
https://www.biorxiv.org/content/10.1101/2022.03.17.484714v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Méreau A, Lerivray H, Viet J, Hardy S, Paillard L, Audic Y. Exonization by the Emergence of a Cleavage-Polyadenylation Site. bioRxiv. 2022;[preprint] doi:10.1101/2022.03.17.484714.

Interaction of transcription factors Islet2 and Nr2f1b to control vascular patterning during zebrafish development

Authors:
Wang YS, Huang YS, Chiu CC, Wu TY, Zhou JQ, Liang SR, Tai MH, Wu CY
Citation:
Biochem Biophys Res Commun. 2022 Mar 9;604:123-129. doi: 10.1016/j.bbrc.2022.03.042. Online ahead of print
Epub:
Not Epub
Abstract:
Many regulators controlling arterial identity are well described; however, transcription factors that promote vein identity and...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0006291X22003679
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang YS, Huang YS, Chiu CC, Wu TY, Zhou JQ, Liang SR, Tai MH, Wu CY. Interaction of transcription factors Islet2 and Nr2f1b to control vascular patterning during zebrafish development. Biochem Biophys Res Commun. 2022 Mar 9;604:123-129. doi: 10.1016/j.bbrc.2022.03.042. Online ahead of print.

Reverse Genetic Approach to Identify Regulators of Pigmentation using Zebrafish

Authors:
Sharma B, Subramaniam YJ, Ayyappa Raja D, Aggarwal A, Sivasubbu S, Natarajan VT
Citation:
J Vis Exp. 2022 Mar 1;(181):e62955. doi: 10.3791/62955
Epub:
Not Epub
Abstract:
Melanocytes are specialized neural crest-derived cells present in the epidermal skin. These cells synthesize melanin pigment...
Link:
https://www.jove.com/t/62955/reverse-genetic-approach-to-identify-regulators-pigmentation-using
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sharma B, Subramaniam YJ, Ayyappa Raja D, Aggarwal A, Sivasubbu S, Natarajan VT. Reverse Genetic Approach to Identify Regulators of Pigmentation using Zebrafish. J Vis Exp. 2022 Mar 1;(181):e62955. doi: 10.3791/62955.

Complete Depletion of Primordial Germ Cells Results in Masculinization of Monopterus albus, a Protogynous Hermaphroditic Fish

Authors:
Hou M, Feng K, Luo H, Jiang Y, Xu W, Li Y, Song Y, Chen J, Tao B, Zhu Z, Hu W
Citation:
Mar Biotechnol (NY). 2022 Mar 18. doi: 10.1007/s10126-022-10106-2. Online ahead of print
Epub:
Yes
Abstract:
Primordial germ cells (PGCs) play an important role in sexual fate determination and gonadal development in gonochoristic fish...
Link:
https://link.springer.com/article/10.1007/s10126-022-10106-2
Delivery Method:
microinjection
Organism or Cell Type:
Monopterus albus (rice field eel)
Citation Extract:
Hou M, Feng K, Luo H, Jiang Y, Xu W, Li Y, Song Y, Chen J, Tao B, Zhu Z, Hu W. Complete Depletion of Primordial Germ Cells Results in Masculinization of Monopterus albus, a Protogynous Hermaphroditic Fish. Mar Biotechnol (NY). 2022 Mar 18. doi: 10.1007/s10126-022-10106-2. Online ahead of print.

Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis

Authors:
Haraoka Y, Akieda Y, Nagai Y, Mogi C, Ishitani T
Citation:
Nat Commun. 2022;13(1):1417. doi:10.1038/s41467-022-29061-6
Epub:
Not Epub
Abstract:
Most tumours are thought to arise through oncogenic cell generation followed by additional mutations. How a new oncogenic cell...
Link:
https://www.nature.com/articles/s41467-022-29061-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Haraoka Y, Akieda Y, Nagai Y, Mogi C, Ishitani T. Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis. Nat Commun. 2022;13(1):1417. doi:10.1038/s41467-022-29061-6.

Heat shock induces premature transcript termination and reconfigures the human transcriptome

Authors:
Cugusi S, Mitter R, Kelly GP, Walker J, Han Z, Pisano P, Wierer M, Stewart A, Svejstrup JQ
Citation:
Mol Cell. 2022;[Epub] doi:10.1016/j.molcel.2022.01.007
Epub:
Yes
Abstract:
The heat shock (HS) response involves rapid induction of HS genes, whereas transcriptional repression is established more...
Link:
https://www.sciencedirect.com/science/article/pii/S1097276522000077
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Cugusi S, Mitter R, Kelly GP, Walker J, Han Z, Pisano P, Wierer M, Stewart A, Svejstrup JQ. Heat shock induces premature transcript termination and reconfigures the human transcriptome. Mol Cell. 2022;[Epub] doi:10.1016/j.molcel.2022.01.007.

Sea anemone Frizzled receptors play partially redundant roles in the oral-aboral axis patterning

Authors:
Niedermoser I, Lebedeva T, Genikhovich G
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.03.15.484449
Epub:
Not Epub
Abstract:
Canonical Wnt (cWnt) signaling is involved in a plethora of basic developmental processes such as endomesoderm specification,...
Link:
https://www.biorxiv.org/content/10.1101/2022.03.15.484449v1
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Niedermoser I, Lebedeva T, Genikhovich G. Sea anemone Frizzled receptors play partially redundant roles in the oral-aboral axis patterning. bioRxiv. 2022;[preprint] doi:10.1101/2022.03.15.484449 .

Kif15 Is Required in the Development of Auditory System Using Zebrafish as a Model

Authors:
Zheng S, Tang D, Wang X, Liu C, Zuo N, Yan R, Wu C, Ma J, Wang C, Xu H, He Y, Liu D, Liu S
Citation:
Front Mol Neurosci. 2022;15:844568. doi:10.3389/fnmol.2022.844568
Epub:
Not Epub
Abstract:
Kif15, a kinesin family member, is powerful in the formation of bipolar spindles. There is emerging evidence indicating that...
Link:
https://www.frontiersin.org/articles/10.3389/fnmol.2022.844568/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zheng S, Tang D, Wang X, Liu C, Zuo N, Yan R, Wu C, Ma J, Wang C, Xu H, He Y, Liu D, Liu S. Kif15 Is Required in the Development of Auditory System Using Zebrafish as a Model. Front Mol Neurosci. 2022;15:844568. doi:10.3389/fnmol.2022.844568.

Splicing is an alternate oncogenic pathway activation mechanism in glioma

Authors:
Siddaway R, Milos S, Vadivel AKA, Dobson THW, Swaminathan J, Ryall S, Pajovic S, Patel PG, Nazarian J, Becher O, Brudno M, Ramani A, Gopalakrishnan V, Hawkins C
Citation:
Nat Commun. 2022 Jan 31;13(1):588. doi: 10.1038/s41467-022-28253-4
Epub:
Not Epub
Abstract:
High-grade diffuse glioma (HGG) is the leading cause of brain tumour death. While the genetic drivers of HGG have been well...
Link:
https://www.nature.com/articles/s41467-022-28253-4
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: U87 GBM, pediatric and adult HGG cells
Citation Extract:
Siddaway R, Milos S, Vadivel AKA, Dobson THW, Swaminathan J, Ryall S, Pajovic S, Patel PG, Nazarian J, Becher O, Brudno M, Ramani A, Gopalakrishnan V, Hawkins C. Splicing is an alternate oncogenic pathway activation mechanism in glioma. Nat Commun. 2022 Jan 31;13(1):588. doi: 10.1038/s41467-022-28253-4.

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