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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Generation of Protein-Phosphorodiamidate Morpholino Oligomer Conjugates for Efficient Cellular Delivery via Anthrax Protective Antigen
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Citation:
Methods Mol Biol. 2022;2434:129-141. Humana, New York, NY. doi:10.1007/978-1-0716-2010-6_8 Epub:
Not Epub Abstract:
Phosphorodiamidate morpholino oligomers (PMOs) offer great promise as therapeutic agents for translation blocking or splice... Delivery Method:
peptide-linked Citation Extract: Palacio-Castañeda V, Brock R, Verdurmen WPR. Generation of Protein-Phosphorodiamidate Morpholino Oligomer Conjugates for Efficient Cellular Delivery via Anthrax Protective Antigen. Methods Mol Biol. 2022;2434:129-141. Humana, New York, NY. doi:10.1007/978-1-0716-2010-6_8. |
Zygotic hypoxia-inducible factor alpha regulates spicule elongation in the sea urchin embryo
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Citation:
Dev Biol. 2022 Feb 17;484:63-74. doi: 10.1016/j.ydbio.2022.02.004. Online ahead of print Epub:
Not Epub Abstract:
Sea urchin larval skeletons are produced by skeletogenic primary mesenchyme cells (PMCs), which migrate to form two... Delivery Method:
microinjection Organism or Cell Type:
sea urchin Citation Extract: Chang WL, Su YH. Zygotic hypoxia-inducible factor alpha regulates spicule elongation in the sea urchin embryo. Dev Biol. 2022 Feb 17;484:63-74. doi: 10.1016/j.ydbio.2022.02.004. Online ahead of print. |
Development of DG9 peptide-conjugated single- and multi-exon skipping therapies for the treatment of Duchenne muscular dystrophy
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Citation:
Proc Natl Acad Sci U S A. 2022 Mar 1;119(9):e2112546119. doi: 10.1073/pnas.2112546119 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is primarily caused by out-of-frame deletions in the dystrophin gene. Exon skipping using... Delivery Method:
peptide-linked Organism or Cell Type:
mice hDMDdel52;mdx Citation Extract: Lim KRQ, Woo S, Melo D, Huang Y, Dzierlega K, Shah MNA, Aslesh T, Roshmi RR, Echigoya Y, Maruyama R, Moulton HM, Yokota T. Development of DG9 peptide-conjugated single- and multi-exon skipping therapies for the treatment of Duchenne muscular dystrophy. Proc Natl Acad Sci U S A. 2022 Mar 1;119(9):e2112546119. doi: 10.1073/pnas.2112546119. |
Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders
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Citation:
Science. 2022 Feb 18;375(6582):eabm4459. doi:10.1126/science.abm4459 Epub:
Not Epub Abstract:
The blood-brain barrier (BBB) protects the central nervous system (CNS) from harmful blood-borne factors. Although BBB... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Martin M, Vermeiren S, Bostaille N, Eubelen M, Spitzer D, Vermeersch M, Profaci CP, Pozuelo E, Toussay X, Vanhollebeke B. Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders. Science. 2022 Feb 18;375(6582):eabm4459. doi:10.1126/science.abm4459. |
Label-Free Detection of Morpholino-DNA Hybridization Using a Silicon Photonics Suspended Slab Micro-Ring Resonator
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Citation:
IEEE Photon J. 2021;14(4):6600809. doi:10.1109/JPHOT.2021.3098680 Epub:
Not Epub Abstract:
In this study, deoxyribonucleic acid (DNA) hybridization was demonstrated using a suspended silicon photonics micro-ring... Citation Extract: Yousuf S, Kim J, Orozaliev A, Dahlem MS, Song Y-A, Viegas J. Label-Free Detection of Morpholino-DNA Hybridization Using a Silicon Photonics Suspended Slab Micro-Ring Resonator. IEEE Photon J. 2021;14(4):6600809. doi:10.1109/JPHOT.2021.3098680. |
Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion in zebrafish germ-layer progenitor cells
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Citation:
Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2122030119. doi: 10.1073/pnas.2122030119 Epub:
Yes Abstract:
Tension of the actomyosin cell cortex plays a key role in determining cell-cell contact growth and size. The level of cortical... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Slováková J, Sikora M, Arslan FN, Caballero-Mancebo S, Krens SFG, Kaufmann WA, Merrin J, Heisenberg CP. Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion in zebrafish germ-layer progenitor cells. Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2122030119. doi: 10.1073/pnas.2122030119. |
A female carrier of spinal and bulbar muscular atrophy diagnosed with DNAJB6-related distal myopathy
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Citation:
J Hum Genet. 2022 Feb 15. doi: 10.1038/s10038-022-01022-3. Online ahead of print Epub:
Not Epub Abstract:
Mutations in the DNAJB6 gene cause limb girdle muscular dystrophy D1 (LGMD D1) and distal myopathy with rimmed vacuoles. With... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xu L, Geng H, Lv X, Wang G, Yan C, Zhang D, Lin P. A female carrier of spinal and bulbar muscular atrophy diagnosed with DNAJB6-related distal myopathy. J Hum Genet. 2022 Feb 15. doi: 10.1038/s10038-022-01022-3. Online ahead of print. |
Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism
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Citation:
Molecules. 2022;27(4):1290. doi:10.3390/molecules27041290 Epub:
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Zebrafish (ZF; Danio rerio) larvae have become a popular in vivo model in drug metabolism studies. Here, we investigated the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Park YM, Dahlem C, Meyer MR, Kiemer AK, Müller R, Herrmann J. Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism. Molecules. 2022;27(4):1290. doi:10.3390/molecules27041290. |
Antisense oligonucleotides targeting exon 11 are able to partially rescue the Neurofibromatosis Type 2 phenotype in vitro
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.02.11.479859 Epub:
Not Epub Abstract:
Neurofibromatosis type 2 (NF2) is an autosomal dominant condition characterized by the development of multiple tumours of the... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: human primary neurofibromatosis cells Citation Extract: Catasus N, Rosas I, Bonache S, Negro A, Plana A, Salvador H, Serra E, Blanco I, Castellanos E. Antisense oligonucleotides targeting exon 11 are able to partially rescue the Neurofibromatosis Type 2 phenotype in vitro. bioRxiv. 2022;[preprint] doi:10.1101/2022.02.11.479859 . |
The E3 Ubiquitin Ligase Mindbomb1 controls planar cell polarity-dependent convergent extension movements during zebrafish gastrulation
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Citation:
Elife. 2022 Feb 10;11:e71928. doi: 10.7554/eLife.71928. Online ahead of print Epub:
Not Epub Abstract:
Vertebrate Delta/Notch signaling involves multiple ligands, receptors and transcription factors. Delta endocytosis - a critical... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Saraswathy VM, Kurup AJ, Sharma P, Polès S, Poulain M, Fürthauer M. The E3 Ubiquitin Ligase Mindbomb1 controls planar cell polarity-dependent convergent extension movements during zebrafish gastrulation. Elife. 2022 Feb 10;11:e71928. doi: 10.7554/eLife.71928. Online ahead of print. |