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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish

Authors:
Lim KH, Chang YC, Chiang YH, Lin HC, Chang CY, Lin CS, Huang L, Wang WT, Gon-Shen Chen C, Chou WC, Kuo YY
Citation:
Blood Cancer J. 2016 Oct 7;6(10):e481. doi: 10.1038/bcj.2016.83
Epub:
Not Epub
Abstract:
CALR mutations are identified in about 30% of JAK2/MPL-unmutated myeloproliferative neoplasms (MPNs) including essential...
Link:
http://www.nature.com/bcj/journal/v6/n10/full/bcj201683a.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lim KH, Chang YC, Chiang YH, Lin HC, Chang CY, Lin CS, Huang L, Wang WT, Gon-Shen Chen C, Chou WC, Kuo YY. Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish. Blood Cancer J. 2016 Oct 7;6(10):e481. doi: 10.1038/bcj.2016.83.

Effects of Cyclin Dependent Kinase 9 inhibition on zebrafish larvae

Authors:
Matrone G, Mullins JJ, Tucker CS, Denvir MA
Citation:
Cell Cycle. 2016 Oct 7: [Epub ahead of print] doi:10.1080/15384101.2016.1231283
Epub:
Yes
Abstract:
CDK9 is a known regulator of cellular transcription, growth and proliferation. Small molecule inhibitors are currently being...
Link:
http://www.tandfonline.com/doi/full/10.1080/15384101.2016.1231283
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Matrone G, Mullins JJ, Tucker CS, Denvir MA. Effects of Cyclin Dependent Kinase 9 inhibition on zebrafish larvae. Cell Cycle. 2016 Oct 7: [Epub ahead of print] doi:10.1080/15384101.2016.1231283.

Antagonism between β-catenin and Gata.a sequentially segregates the germ layers of ascidian embryos

Authors:
Imai KS, Hudson C, Oda-Ishii I, Yasuo H, Satou Y
Citation:
Development. 2016;[Epub ahead of print] doi: 10.1242/dev.141481
Epub:
Not Epub
Abstract:
Many animal embryos use nuclear β-catenin (nβ-catenin) during the segregation of endomesoderm (or endoderm) from ectoderm. This...
Link:
http://dev.biologists.org/content/early/2016/10/04/dev.141481
Delivery Method:
microinjection
Citation Extract:
Imai KS, Hudson C, Oda-Ishii I, Yasuo H, Satou Y. Antagonism between β-catenin and Gata.a sequentially segregates the germ layers of ascidian embryos. Development. 2016;[Epub ahead of print] doi: 10.1242/dev.141481.

Diaphanous gene mutation affects spiral cleavage and chirality in snails

Authors:
Kuroda R, Fujikura K, Abe M, Hosoiri Y, Asakawa S, Shimizu M, Umeda S, Ichikawa F, Takahashi H
Citation:
Sci Rep. 2016;6:34809. doi:10.1038/srep34809
Epub:
Not Epub
Abstract:
L-R (left and right) symmetry breaking during embryogenesis and the establishment of asymmetric body plan are key issues in...
Link:
http://www.nature.com/articles/srep34809
Delivery Method:
microinjection
Organism or Cell Type:
Lymnaea stagnalis (pond snail)
Citation Extract:
Kuroda R, Fujikura K, Abe M, Hosoiri Y, Asakawa S, Shimizu M, Umeda S, Ichikawa F, Takahashi H. Diaphanous gene mutation affects spiral cleavage and chirality in snails. Sci Rep. 2016;6:34809. doi:10.1038/srep34809.

Thyroid Hormone Acts Locally to Increase Neurogenesis, Neuronal Differentiation, and Dendritic Arbor Elaboration in the Tadpole Visual System

Authors:
Thompson CK, Cline HT
Citation:
J Neurosci. 2016;36(40):10356-75. doi:10.1523/JNEUROSCI.4147-15.2016
Epub:
Not Epub
Abstract:
Thyroid hormone (TH) regulates many cellular events underlying perinatal brain development in vertebrates. Whether and how TH...
Link:
http://www.jneurosci.org/content/36/40/10356.abstract
Delivery Method:
electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Thompson CK, Cline HT. Thyroid Hormone Acts Locally to Increase Neurogenesis, Neuronal Differentiation, and Dendritic Arbor Elaboration in the Tadpole Visual System. J Neurosci. 2016;36(40):10356-75. doi:10.1523/JNEUROSCI.4147-15.2016.

Function-driven discovery of disease genes in zebrafish using an integrated genomics big data resource

Authors:
Shim H, Kim JH, Kim CY, Hwang S, Kim H, Yang S, Lee JE, Lee I
Citation:
Nucl Acid Res. 2016;[Epub ahead of print] doi:10.1093/nar/gkw897
Epub:
Yes
Abstract:
Whole exome sequencing (WES) accelerates disease gene discovery using rare genetic variants, but further statistical and...
Link:
http://nar.oxfordjournals.org/content/early/2016/10/05/nar.gkw897.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shim H, Kim JH, Kim CY, Hwang S, Kim H, Yang S, Lee JE, Lee I. Function-driven discovery of disease genes in zebrafish using an integrated genomics big data resource. Nucl Acid Res. 2016;[Epub ahead of print] doi:10.1093/nar/gkw897.

Survival Motor Neuron (SMN) protein is required for normal mouse liver development

Authors:
Szunyogova E, Zhou H, Maxwell GK, Powis RA, Muntoni F, Gillingwater TH, Parson SH
Citation:
Sci Rep. 2016;6:34635. doi:10.1038/srep34635
Epub:
Not Epub
Abstract:
Spinal Muscular Atrophy (SMA) is caused by mutation or deletion of the survival motor neuron 1 (SMN1) gene. Decreased levels of...
Link:
http://www.nature.com/articles/srep34635
Delivery Method:
injection
Organism or Cell Type:
SMA mice
Citation Extract:
Szunyogova E, Zhou H, Maxwell GK, Powis RA, Muntoni F, Gillingwater TH, Parson SH. Survival Motor Neuron (SMN) protein is required for normal mouse liver development. Sci Rep. 2016;6:34635. doi:10.1038/srep34635.

Developmental Vitamin D Availability Impacts Hematopoietic Stem Cell Production

Authors:
Cortes M, Chen MJ, Stachura DL, Liu SY, Kwan W, Wright F, Vo LT, Theodore LN, Esain V, Frost IM, Schlaeger TM, Goessling W, Daley GQ, North TE
Citation:
Cell Rep. 2016;17:458-468. doi:10.1016/j.celrep.2016.09.012
Epub:
Not Epub
Abstract:
Vitamin D insufficiency is a worldwide epidemic affecting billions of individuals, including pregnant women and children....
Link:
http://www.cell.com/cell-reports/abstract/S2211-1247(16)31217-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cortes M, Chen MJ, Stachura DL, Liu SY, Kwan W, Wright F, Vo LT, Theodore LN, Esain V, Frost IM, Schlaeger TM, Goessling W, Daley GQ, North TE. Developmental Vitamin D Availability Impacts Hematopoietic Stem Cell Production. Cell Rep. 2016;17:458-468. doi:10.1016/j.celrep.2016.09.012.

EphA7 modulates apical constriction of hindbrain neuroepithelium during neurulation in Xenopus

Authors:
Wang X, Sun J, Li C, Mao B
Citation:
Biochem Biophys Res Commun. 2016 Sep 27. pii: S0006-291X(16)31612-6. doi: 10.1016/j.bbrc.2016.09.138
Epub:
Yes
Abstract:
Eph receptor tyrosine kinases (RTKs) and their ephrin ligands play multiple roles in the developing nervous system, including...
Link:
http://www.sciencedirect.com/science/article/pii/S0006291X16316126
Organism or Cell Type:
Xenopus
Citation Extract:
Wang X, Sun J, Li C, Mao B. EphA7 modulates apical constriction of hindbrain neuroepithelium during neurulation in Xenopus. Biochem Biophys Res Commun. 2016 Sep 27. pii: S0006-291X(16)31612-6. doi: 10.1016/j.bbrc.2016.09.138.

Phosphorylation of Kif26b Promotes Its Polyubiquitination and Subsequent Proteasomal Degradation during Kidney Development

Authors:
Terabayashi T, Sakaguchi M, Shinmyozu K, Ohshima T, Johjima A, Ogura T, Miki H, Nishinakamura R
Citation:
PLoS ONE. 2012;7(6): e39714. doi:10.1371/journal.pone.0039714
Epub:
Not Epub
Abstract:
Kif26b, a member of the kinesin superfamily proteins (KIFs), is essential for kidney development. Kif26b expression is...
Link:
http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0039714
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse kidney explant
Citation Extract:
Terabayashi T, Sakaguchi M, Shinmyozu K, Ohshima T, Johjima A, Ogura T, Miki H, Nishinakamura R. Phosphorylation of Kif26b Promotes Its Polyubiquitination and Subsequent Proteasomal Degradation during Kidney Development. PLoS ONE. 2012;7(6): e39714. doi:10.1371/journal.pone.0039714.

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