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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Persistence, period and precision of autonomous cellular oscillators from the zebrafish segmentation clock

Authors:
Webb AB, Lengyel IM, Jörg DJ, Valentin G, Jülicher F, Morelli LG, Oates AC
Citation:
Elife. 2016 Feb 13;5. pii: e08438. doi: 10.7554/eLife.08438
Epub:
Not Epub
Abstract:
In vertebrate development, the sequential and rhythmic segmentation of the body axis is regulated by a "segmentation clock...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Webb AB, Lengyel IM, Jörg DJ, Valentin G, Jülicher F, Morelli LG, Oates AC. Persistence, period and precision of autonomous cellular oscillators from the zebrafish segmentation clock. Elife. 2016 Feb 13;5. pii: e08438. doi: 10.7554/eLife.08438.

ATR promotes cilia signalling: links to developmental impacts

Authors:
Stiff T, Casar Tena T, O'Driscoll M, Jeggo PA, Philipp M
Citation:
Hum Mol Genet. 2016 Apr 15;25(8):1574-87. doi: 10.1093/hmg/ddw034. Epub 2016 Feb 11
Epub:
Not Epub
Abstract:
Mutations in ATR (ataxia telangiectasia and RAD3-related) cause Seckel syndrome (ATR-SS), a microcephalic primordial dwarfism...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stiff T, Casar Tena T, O'Driscoll M, Jeggo PA, Philipp M. ATR promotes cilia signalling: links to developmental impacts. Hum Mol Genet. 2016 Apr 15;25(8):1574-87. doi: 10.1093/hmg/ddw034. Epub 2016 Feb 11.

The Zebrafish Equivalent of Alzheimer's Disease-Associated PRESENILIN Isoform PS2V Regulates Inflammatory and Other Responses to Hypoxic Stress

Authors:
Ebrahimie E, Moussavi-Nik SH, Newman M, Van Der Hoek M, Lardelli M
Citation:
J Alzheimers Dis. 2016 Mar 31. [Epub ahead of print]
Epub:
Yes
Abstract:
Dominant mutations in the PRESENILIN genes PSEN1 and PSEN2 cause familial Alzheimer's disease (fAD) that usually shows...
Organism or Cell Type:
zebrafish
Citation Extract:
Ebrahimie E, Moussavi-Nik SH, Newman M, Van Der Hoek M, Lardelli M. The Zebrafish Equivalent of Alzheimer's Disease-Associated PRESENILIN Isoform PS2V Regulates Inflammatory and Other Responses to Hypoxic Stress. J Alzheimers Dis. 2016 Mar 31. [Epub ahead of print].

Temporal effects of Notch signaling and potential cooperation with multiple downstream effectors on adenohypophysis cell specification in zebrafish

Authors:
Nakahara Y, Muto A, Hirabayashi R, Sakuma T, Yamamoto T, Kume S, Kikuchi Y
Citation:
Genes Cells. 2016 Mar 29. doi: 10.1111/gtc.12358. [Epub ahead of print]
Epub:
Yes
Abstract:
The adenohypophysis (AH) consists of six distinct types of hormone-secreting cells. In zebrafish, although proper...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nakahara Y, Muto A, Hirabayashi R, Sakuma T, Yamamoto T, Kume S, Kikuchi Y. Temporal effects of Notch signaling and potential cooperation with multiple downstream effectors on adenohypophysis cell specification in zebrafish. Genes Cells. 2016 Mar 29. doi: 10.1111/gtc.12358. [Epub ahead of print].

APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p

Authors:
Wang K, Liu CY, Zhou LY, Wang JX, Wang M, Zhao B, Zhao WK, Xu SJ, Fan LH, Zhang XJ, Feng C, Wang CQ, Zhao YF, Li PF
Citation:
Nat Commun. 2015 Apr 10;6:6779. doi: 10.1038/ncomms7779
Epub:
Not Epub
Abstract:
The abnormal autophagy is associated with a variety of cardiovascular diseases. Long noncoding RNAs (lncRNAs) are emerging as...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: mouse primary cardiomyocytes
Citation Extract:
Wang K, Liu CY, Zhou LY, Wang JX, Wang M, Zhao B, Zhao WK, Xu SJ, Fan LH, Zhang XJ, Feng C, Wang CQ, Zhao YF, Li PF. APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p. Nat Commun. 2015 Apr 10;6:6779. doi: 10.1038/ncomms7779.

Correction of the Pathogenic Alternative Splicing, Caused by the Common GNB3 c.825C>T allele, Using a Novel, Antisense Morpholino

Authors:
McGlinchey JC, Tummala H, Lester DH
Citation:
Nucleic Acid Ther. 2016 Mar 30. [Epub ahead of print]
Epub:
Yes
Abstract:
The very common GNB3 c.825C>T polymorphism (rs5443) is present in approximately half of all human chromosomes. Significantly...
Organism or Cell Type:
cell culture: human lymphoblast cell line ebv transformed
Citation Extract:
McGlinchey JC, Tummala H, Lester DH. Correction of the Pathogenic Alternative Splicing, Caused by the Common GNB3 c.825C>T allele, Using a Novel, Antisense Morpholino. Nucleic Acid Ther. 2016 Mar 30. [Epub ahead of print].

4-Dimensional light-sheet microscopy to elucidate shear stress modulation of cardiac trabeculation

Authors:
Lee J, Fei P, Packard RRS, Kang H, Xu H, Baek KI, Jen N, Chen J, Yen H, Jay Kuo CCJ, Chi NC, Ho C-M, Li R, Hsiai TK
Citation:
JCI. 2016;[Epub ahead of print] doi:10.1172/JCI83496
Epub:
Yes
Abstract:
Hemodynamic shear forces are intimately linked with cardiac development, during which trabeculae form a network of branching...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee J, Fei P, Packard RRS, Kang H, Xu H, Baek KI, Jen N, Chen J, Yen H, Jay Kuo CCJ, Chi NC, Ho C-M, Li R, Hsiai TK. 4-Dimensional light-sheet microscopy to elucidate shear stress modulation of cardiac trabeculation. JCI. 2016;[Epub ahead of print] doi:10.1172/JCI83496.

Ca2+/H+ exchange by acidic organelles regulates cell migration in vivo

Authors:
Melchionda M, Pittman JK, Mayor R, Patel S
Citation:
J Cell Biol. 2016;[Epub ahead of print] doi:10.1083/jcb.201510019
Epub:
Yes
Abstract:
Increasing evidence implicates Ca2+ in the control of cell migration. However, the underlying mechanisms are incompletely...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Melchionda M, Pittman JK, Mayor R, Patel S. Ca2+/H+ exchange by acidic organelles regulates cell migration in vivo. J Cell Biol. 2016;[Epub ahead of print] doi:10.1083/jcb.201510019.

Knockdown of fast skeletal myosin-binding protein C in zebrafish results in a severe skeletal myopathy

Authors:
Li M, Andersson-Lendahl M, Sejersen T, Arner A
Citation:
J Gen Physiol. 2016;147:309-322. doi:10.1085/jgp.201511452
Epub:
Not Epub
Abstract:
Myosin-binding protein C (MyBPC) in the muscle sarcomere interacts with several contractile and structural proteins. Mutations...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li M, Andersson-Lendahl M, Sejersen T, Arner A. Knockdown of fast skeletal myosin-binding protein C in zebrafish results in a severe skeletal myopathy. J Gen Physiol. 2016;147:309-322. doi:10.1085/jgp.201511452.

Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage Migration

Authors:
Berg RD, Levitte S, O'Sullivan MP, O'Leary SM, Cambier CJ, Cameron J, Takaki KK, Moens CB, Tobin DM, Keane J, Ramakrishnan L
Citation:
Cell. 2016 Mar 24;165(1):139-52. doi: 10.1016/j.cell.2016.02.034
Epub:
Not Epub
Abstract:
A zebrafish genetic screen for determinants of susceptibility to Mycobacterium marinum identified a hypersusceptible mutant...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Berg RD, Levitte S, O'Sullivan MP, O'Leary SM, Cambier CJ, Cameron J, Takaki KK, Moens CB, Tobin DM, Keane J, Ramakrishnan L. Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage Migration. Cell. 2016 Mar 24;165(1):139-52. doi: 10.1016/j.cell.2016.02.034.

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