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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Authors:
Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang , Chen M-H, Pers TH, <-Authors removed - database limit-> ICBP Consortium, AGEN Consortium, CARDIOGRAM, CHARGe-Heart Failure Group, ECHOGen Consortium, Zemunik T, Lehtimaki T, Illig T, Aspelund T, Nikopensius T, Esko T, Tanaka T, Gyllensten U, Volker U, Emilsson V, Vitart V, Aalto V, Gudnason V, Chouraki V, Chen W-M, Igl W, Marz W, Koenig W, Lieb W, Loos RJF, Liu Y, Snieder H, Pramstaller PP, Parsa A, O'Connell JR, Susztak K, Hamet P, Tremblay J, de Boer IH, Boger CA, Goessling W, Chasman DI, Kottgen A, Kao WHL, Fox CS.
Citation:
Nat Comm. 2016;7:10023. doi:10.1038/ncomms10023
Epub:
Not Epub
Abstract:
Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality...
Link:
http://www.nature.com/ncomms/2016/160121/ncomms10023/full/ncomms10023.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang , Chen M-H, Pers TH, <-Authors removed - database limit-> ICBP Consortium, AGEN Consortium, CARDIOGRAM, CHARGe-Heart Failure Group, ECHOGen Consortium, Zemunik T, Lehtimaki T, Illig T, Aspelund T, Nikopensius T, Esko T, Tanaka T, Gyllensten U, Volker U, Emilsson V, Vitart V, Aalto V, Gudnason V, Chouraki V, Chen W-M, Igl W, Marz W, Koenig W, Lieb W, Loos RJF, Liu Y, Snieder H, Pramstaller PP, Parsa A, O'Connell JR, Susztak K, Hamet P, Tremblay J, de Boer IH, Boger CA, Goessling W, Chasman DI, Kottgen A, Kao WHL, Fox CS. . Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nat Comm. 2016;7:10023. doi:10.1038/ncomms10023.

Macrophage Recruitment Contributes to Regeneration of Mechanosensory Hair Cells in the Zebrafish Lateral Line

Authors:
Carrillo SA, Anguita-Salinas C, Peña OA, Morales RA, Muñoz-Sánchez S, Muñoz-Montecinos C, Paredes-Zúñiga S, Tapia K, Allende ML
Citation:
J Cell Biochem. 2016 Jan 11. doi: 10.1002/jcb.25487. [Epub ahead of print]
Epub:
Yes
Abstract:
In vertebrates, damage to mechanosensory hair cells elicits an inflammatory response, including rapid recruitment of...
Link:
http://onlinelibrary.wiley.com/wol1/doi/10.1002/jcb.25487/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Carrillo SA, Anguita-Salinas C, Peña OA, Morales RA, Muñoz-Sánchez S, Muñoz-Montecinos C, Paredes-Zúñiga S, Tapia K, Allende ML. Macrophage Recruitment Contributes to Regeneration of Mechanosensory Hair Cells in the Zebrafish Lateral Line. J Cell Biochem. 2016 Jan 11. doi: 10.1002/jcb.25487. [Epub ahead of print].

Vitamin D receptor signaling is required for heart development in zebrafish embryo

Authors:
Kwon HJ
Citation:
Biochem Biophys Res Commun. 2016 Jan 18. pii: S0006-291X(16)30103-6. doi: 10.1016/j.bbrc.2016.01.103. [Epub ahead of print]
Epub:
Yes
Abstract:
Vitamin D has been found to be associated with cardiovascular diseases. However, the role of vitamin D in heart development...
Link:
http://www.sciencedirect.com/science/article/pii/S0006291X16301036
Organism or Cell Type:
zebrafish
Citation Extract:
Kwon HJ. Vitamin D receptor signaling is required for heart development in zebrafish embryo. Biochem Biophys Res Commun. 2016 Jan 18. pii: S0006-291X(16)30103-6. doi: 10.1016/j.bbrc.2016.01.103. [Epub ahead of print].

Antisense targeting of 3'end elements involved in DUX4 mRNA processing is an efficient therapeutic strategy for Facioscapulohumeral Dystrophy: a new gene silencing approach

Authors:
Marsollier AC, Ciszewski L, Mariot V, Popplewell L, Voit T, Dickson G, Dumonceaux J
Citation:
Hum Mol Genet. 2016 Jan 19. pii: ddw015. [Epub ahead of print]
Epub:
Yes
Abstract:
Defects in mRNA 3' end formation have been described to alter transcription termination, transport of the mRNA from the...
Link:
http://hmg.oxfordjournals.org/content/early/2016/01/19/hmg.ddw015.abstract
Delivery Method:
DNA leash and lipofectamine
Organism or Cell Type:
cell culture: differentiated immortalized FSHD myotubes
Citation Extract:
Marsollier AC, Ciszewski L, Mariot V, Popplewell L, Voit T, Dickson G, Dumonceaux J. Antisense targeting of 3'end elements involved in DUX4 mRNA processing is an efficient therapeutic strategy for Facioscapulohumeral Dystrophy: a new gene silencing approach. Hum Mol Genet. 2016 Jan 19. pii: ddw015. [Epub ahead of print].

Patterns of thyroid hormone receptor expression in zebrafish and generation of a novel model of resistance to thyroid hormone action

Authors:
Marelli F, Carra S, Agostini M, Cotelli F, Peeters R, Chatterjee K, Persani L
Citation:
Mol Cell Endocrinol. 2016 Jan 20. pii: S0303-7207(16)30020-X. doi: 10.1016/j.mce.2016.01.020. [Epub ahead of print]
Epub:
Yes
Abstract:
Resistance to thyroid hormone can be due to heterozygous, dominant negative (DN) THRA (RTHα) or THRB (RTHβ) mutations, but the...
Link:
http://www.sciencedirect.com/science/article/pii/S030372071630020X
Organism or Cell Type:
zebrafish
Citation Extract:
Marelli F, Carra S, Agostini M, Cotelli F, Peeters R, Chatterjee K, Persani L. Patterns of thyroid hormone receptor expression in zebrafish and generation of a novel model of resistance to thyroid hormone action. Mol Cell Endocrinol. 2016 Jan 20. pii: S0303-7207(16)30020-X. doi: 10.1016/j.mce.2016.01.020. [Epub ahead of print].

Deiodinase knockdown affects zebrafish eye development at the level of gene expression, morphology and function

Authors:
Houbrechts AM, Vergauwen L, Bagci E, Van Houcke J, Heijlen M, Kulemeka B, Hyde DR, Knapen D, Darras VM
Citation:
Mol Cell Endocrinol. 2016 Jan 20. pii: S0303-7207(16)30018-1. doi: 10.1016/j.mce.2016.01.018. [Epub ahead of print]
Epub:
Yes
Abstract:
Retinal development in vertebrates relies extensively on thyroid hormones. Their local availability is tightly controlled by...
Link:
http://www.sciencedirect.com/science/article/pii/S0303720716300181
Organism or Cell Type:
zebrafish
Citation Extract:
Houbrechts AM, Vergauwen L, Bagci E, Van Houcke J, Heijlen M, Kulemeka B, Hyde DR, Knapen D, Darras VM. Deiodinase knockdown affects zebrafish eye development at the level of gene expression, morphology and function. Mol Cell Endocrinol. 2016 Jan 20. pii: S0303-7207(16)30018-1. doi: 10.1016/j.mce.2016.01.018. [Epub ahead of print].

GADD45B mediates podocyte injury in zebrafish by activating the ROS-GADD45B-p38 pathway

Authors:
Chen Z, Wan X, Hou Q, Shi S, Wang L, Chen P, Zhu X, Zeng C, Qin W, Zhou W, Liu Z
Citation:
Cell Death Dis. 2016 Jan 21;7:e2068. doi: 10.1038/cddis.2015.300
Epub:
Not Epub
Abstract:
GADD45 gene has been implicated in cell cycle arrest, cell survival or apoptosis in a cell type specific and context-dependent...
Link:
http://www.nature.com/cddis/journal/v7/n1/full/cddis2015300a.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen Z, Wan X, Hou Q, Shi S, Wang L, Chen P, Zhu X, Zeng C, Qin W, Zhou W, Liu Z. GADD45B mediates podocyte injury in zebrafish by activating the ROS-GADD45B-p38 pathway. Cell Death Dis. 2016 Jan 21;7:e2068. doi: 10.1038/cddis.2015.300.

ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors

Authors:
Mamińska A, Anna Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon T, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M
Citation:
Sci Signal. 2016;9(411):ra8. doi:10.1126/scisignal.aad0848
Epub:
Not Epub
Abstract:
Because signaling mediated by the transcription factor nuclear factor κB (NF-κB) is initiated by ligands and receptors that can...
Link:
http://stke.sciencemag.org/content/9/411/ra8
Organism or Cell Type:
zebrafish
Citation Extract:
Mamińska A, Anna Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon T, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M. ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors. Sci Signal. 2016;9(411):ra8. doi:10.1126/scisignal.aad0848.

Regulatory dissection of the CBX5 and hnRNPA1 bi-directional promoter in human breast cancer cells reveals novel transcript variants differentially associated with HP1α down-regulation in metastatic cells

Authors:
Vad-Nielsen J, Jakobsen KR, Daugaard TF, Thomsen R, Brügmann A, Sørensen BS, Nielsen AL
Citation:
BMC Cancer. 2016;16:32. doi:10.1186/s12885-016-2059-x
Epub:
Not Epub
Abstract:
Background: The three members of the human heterochromatin protein 1 (HP1) family of proteins, HP1α, HP1β, and HPγ, are...
Link:
http://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2059-x
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: MDA-MB-231
Citation Extract:
Vad-Nielsen J, Jakobsen KR, Daugaard TF, Thomsen R, Brügmann A, Sørensen BS, Nielsen AL. Regulatory dissection of the CBX5 and hnRNPA1 bi-directional promoter in human breast cancer cells reveals novel transcript variants differentially associated with HP1α down-regulation in metastatic cells. BMC Cancer. 2016;16:32. doi:10.1186/s12885-016-2059-x.

Identifying domains of EFHC1 involved in ciliary localization, ciliogenesis, and the regulation of Wnt signaling

Authors:
Zhao Y, Shi J, Winey M, Klymkowsky MW
Citation:
Dev Biol. 2016 Jan 16. pii: S0012-1606(15)30212-8. doi: 10.1016/j.ydbio.2016.01.004. [Epub ahead of print]
Epub:
Not Epub
Abstract:
EFHC1 encodes a ciliary protein that has been linked to Juvenile Myoclonic Epilepsy. In ectodermal explants, derived from...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160615302128
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Zhao Y, Shi J, Winey M, Klymkowsky MW. Identifying domains of EFHC1 involved in ciliary localization, ciliogenesis, and the regulation of Wnt signaling. Dev Biol. 2016 Jan 16. pii: S0012-1606(15)30212-8. doi: 10.1016/j.ydbio.2016.01.004. [Epub ahead of print].

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