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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

DNA damage induces a meiotic arrest in mouse oocytes mediated by the spindle assembly checkpoint

Authors:
Collins JK,. Lane SIR, Merriman JA, Jones KT
Citation:
Nat Comm. 2015;6:8553. doi:10.1038/ncomms9553
Epub:
Not Epub
Abstract:
Extensive damage to maternal DNA during meiosis causes infertility, birth defects and abortions. However, it is unknown if...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Collins JK,. Lane SIR, Merriman JA, Jones KT. DNA damage induces a meiotic arrest in mouse oocytes mediated by the spindle assembly checkpoint. Nat Comm. 2015;6:8553. doi:10.1038/ncomms9553.

DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age

Authors:
Marangos P, Stevense M, Niaka K, Lagoudaki M, Nabti I, Jessberger R, John Carroll J
Citation:
Nat Comm. 2015;6:8706. doi:10.1038/ncomms9706
Epub:
Not Epub
Abstract:
In mammalian oocytes DNA damage can cause chromosomal abnormalities that potentially lead to infertility and developmental...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Marangos P, Stevense M, Niaka K, Lagoudaki M, Nabti I, Jessberger R, John Carroll J. DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age. Nat Comm. 2015;6:8706. doi:10.1038/ncomms9706.

Meis3 is required for neural crest invasion of the gut during zebrafish enteric nervous system development

Authors:
Uribe RA, Bronner ME
Citation:
Mol Biol Cell. 2015 Nov 1;26(21):3728-40. doi: 10.1091/mbc.E15-02-0112. Epub 2015 Sep 9
Epub:
Not Epub
Abstract:
During development, vagal neural crest cells fated to contribute to the enteric nervous system migrate ventrally away from the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Uribe RA, Bronner ME. Meis3 is required for neural crest invasion of the gut during zebrafish enteric nervous system development. Mol Biol Cell. 2015 Nov 1;26(21):3728-40. doi: 10.1091/mbc.E15-02-0112. Epub 2015 Sep 9.

A zebrafish model of Poikiloderma with Neutropenia recapitulates the human syndrome hallmarks and traces back neutropenia to the myeloid progenitor

Authors:
Colombo EA, Carra S, Fontana L, Bresciani E, Cotelli F, Larizza L
Citation:
Sci Rep. 2015;5:15814. doi:10.1038/srep15814
Epub:
Not Epub
Abstract:
Poikiloderma with Neutropenia (PN) is an autosomal recessive genodermatosis characterized by early-onset poikiloderma,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Colombo EA, Carra S, Fontana L, Bresciani E, Cotelli F, Larizza L. A zebrafish model of Poikiloderma with Neutropenia recapitulates the human syndrome hallmarks and traces back neutropenia to the myeloid progenitor. Sci Rep. 2015;5:15814. doi:10.1038/srep15814.

Neurogenesis in sea urchin embryos and the diversity of deuterostome neurogenic mechanisms

Authors:
Garner S, Zysk I, Byrne G, Kramer M, Moller D, Taylor V, Burke RD
Citation:
Development. 2015 Oct 28. pii: dev.124503. [Epub ahead of print]
Epub:
Yes
Abstract:
A single origin to the diverse mechanisms of metazoan neurogenesis is suggested by the involvement of common signaling...
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Garner S, Zysk I, Byrne G, Kramer M, Moller D, Taylor V, Burke RD. Neurogenesis in sea urchin embryos and the diversity of deuterostome neurogenic mechanisms. Development. 2015 Oct 28. pii: dev.124503. [Epub ahead of print].

Production of reproductively sterile fish by a non-transgenic gene silencing technology

Authors:
Wong TT, Zohar Y
Citation:
Sci Rep. 2015 Oct 29;5:15822. doi: 10.1038/srep15822
Epub:
Not Epub
Abstract:
We developed a novel bath-immersion technology to produce large numbers of infertile fish. As seafood consumption shifts from...
Delivery Method:
Vivo-Morpholino bathing
Organism or Cell Type:
zebrafish
Citation Extract:
Wong TT, Zohar Y. Production of reproductively sterile fish by a non-transgenic gene silencing technology. Sci Rep. 2015 Oct 29;5:15822. doi: 10.1038/srep15822.

Gene Interference with Morpholinos in a Gold Nanoparticle-Based Delivery Platform in Rat PC12 Cells

Authors:
Deng W, Farnham MM, Goldys EM, Mohammed S, Pilowsky PM
Citation:
J Biomed Nanotechnol. 2015 Dec;11(12):2111-23
Epub:
Not Epub
Abstract:
For the first time the efficiency of gene knockdown of the pituitary adenylate cyclase-activating polypeptide (PACAP) receptor...
Delivery Method:
nanoparticle
Organism or Cell Type:
cell culture: rat PC12
Citation Extract:
Deng W, Farnham MM, Goldys EM, Mohammed S, Pilowsky PM. Gene Interference with Morpholinos in a Gold Nanoparticle-Based Delivery Platform in Rat PC12 Cells. J Biomed Nanotechnol. 2015 Dec;11(12):2111-23.

klf2ash317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes

Authors:
Novodvorsky P, Watson O, Gray C, Wilkinson RN, Reeve S, Smythe C, Beniston R, Plant K, Maguire R, M K Rothman A, Elworthy S, van Eeden FJ, Chico TJ
Citation:
PLoS One. 2015 Oct 27;10(10):e0141611. doi: 10.1371/journal.pone.0141611. eCollection 2015
Epub:
Not Epub
Abstract:
INTRODUCTION AND OBJECTIVES: The zinc-finger transcription factor Krϋppel-like factor 2 (KLF2) transduces blood flow into...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Novodvorsky P, Watson O, Gray C, Wilkinson RN, Reeve S, Smythe C, Beniston R, Plant K, Maguire R, M K Rothman A, Elworthy S, van Eeden FJ, Chico TJ. klf2ash317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes. PLoS One. 2015 Oct 27;10(10):e0141611. doi: 10.1371/journal.pone.0141611. eCollection 2015.

Down-regulation of msrb3 and destruction of normal auditory system development through hair cell apoptosis in zebrafish

Authors:
Shen X, Liu F, Wang Y, Wang H, Ma J, Xia W, Zhang J, Jiang N, Sun S, Wang X, Ma D
Citation:
Int J Dev Biol. 2015;59(4-5-6):195-203
Epub:
Not Epub
Abstract:
Hearing defects can significantly influence quality of life for those who experience them. At this time, 177 deafness genes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shen X, Liu F, Wang Y, Wang H, Ma J, Xia W, Zhang J, Jiang N, Sun S, Wang X, Ma D. Down-regulation of msrb3 and destruction of normal auditory system development through hair cell apoptosis in zebrafish. Int J Dev Biol. 2015;59(4-5-6):195-203.

Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone

Authors:
Jepps TA, Carr G, Lundegaard PR, Olesen SP, Greenwood IA
Citation:
J Physiol. 2015 Oct 27. doi: 10.1113/JP271286. [Epub ahead of print]
Epub:
Yes
Abstract:
KEY POINTS: KCNE4 alters the biophysical properties and cellular localisation of Kv7.4. KCNE4 is expressed in a variety of...
Delivery Method:
Lipofectamine 2000
Citation Extract:
Jepps TA, Carr G, Lundegaard PR, Olesen SP, Greenwood IA. Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone. J Physiol. 2015 Oct 27. doi: 10.1113/JP271286. [Epub ahead of print].

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