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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12356 scientific papers returned from the database with the search filters currently being used below.
There are 12356 scientific papers returned from the database with the search filters currently being used below.
A morpholino oligomer targeting highly conserved internal ribosome entry site sequence is able to inhibit multiple species of picornavirus
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Citation:
Antimicrob Agents Chemother. 2008 Jun;52(6):1970-81. Epub 2008 Mar 17. Epub:
Not Epub Abstract:
Members of the genera Enterovirus and Rhinovirus (family Picornaviridae) cause a wide range of human diseases. An established... Delivery Method:
peptide-coupled Organism or Cell Type:
mice, cell cultures Citation Extract: Stone JK, Rijnbrand R, Stein DA, Ma Y, Yang Y, Iversen PL, Andino R. A morpholino oligomer targeting highly conserved internal ribosome entry site sequence is able to inhibit multiple species of picornavirus. Antimicrob Agents Chemother. 2008 Jun;52(6):1970-81. Epub 2008 Mar 17.. |
A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by notch in Xenopus embryos
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Citation:
Mol Cell. 2003 Aug;12(2):425-35 Epub:
Not Epub Abstract:
MeCP2 is a DNA binding protein that represses transcription of methylated genes in vitro, but the endogenous function of MeCP2... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Stancheva I, Collins AL, Van den Veyver IB, Zoghbi H, Meehan RR. A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by notch in Xenopus embryos. Mol Cell. 2003 Aug;12(2):425-35. |
A perturbation model of the gene regulatory network for oral and aboral ectoderm specification in the sea urchin embryo
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Citation:
Dev Biol. 2009 Mar 4. [Epub ahead of print] Epub:
Not Epub Abstract:
The current gene regulatory network (GRN) for the sea urchin embryo pertains to pregastrular specification functions in the... Organism or Cell Type:
sea urchin Citation Extract: Su YH, Li E, Geiss GK, Longabaugh WJ, Krämer A, Davidson EH. A perturbation model of the gene regulatory network for oral and aboral ectoderm specification in the sea urchin embryo. Dev Biol. 2009 Mar 4. [Epub ahead of print]. |
A PHD12–Snail2 repressive complex epigenetically mediates neural crest epithelial-to-mesenchymal transition
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Citation:
J Cell Biol. 2012;198(6):999-1010. doi: 10.1083/jcb.201203098 Epub:
Not Epub Abstract:
Neural crest cells form within the neural tube and then undergo an epithelial to mesenchymal transition (EMT) to initiate... Delivery Method:
Electroporation Organism or Cell Type:
chick (Gallus gallus) Citation Extract: Strobl-Mazzulla PH, Bronner ME. A PHD12–Snail2 repressive complex epigenetically mediates neural crest epithelial-to-mesenchymal transition. J Cell Biol. 2012;198(6):999-1010. doi: 10.1083/jcb.201203098 . |
A specificity comparison of four antisense types: morpholino, 2'-O-methyl RNA, DNA, and phosphorothioate DNA
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Citation:
Antisense Nucleic Acid Drug Dev. 1997 Jun;7(3):151-7 Epub:
Not Epub Abstract:
Cell-free translation studies were carried out to compare the efficacy and specificity of four antisense structural types: DNA... Delivery Method:
in vitro: TNT Citation Extract: Stein D, Foster E, Huang SB, Weller D, Summerton J. A specificity comparison of four antisense types: morpholino, 2'-O-methyl RNA, DNA, and phosphorothioate DNA. Antisense Nucleic Acid Drug Dev. 1997 Jun;7(3):151-7. |
Antagonism of microRNA Function in Zebrafish Embryos by Using Locked Nucleic Acid Enzymes (LNAzymes)
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Citation:
ChemBioChem. 2012;[Epub ahead of print] doi:10.1002/cbic.201100789 Epub:
Not Epub Abstract:
MicroRNAs (miRNAs) have crucial functions in many cellular processes, such as differentiation, proliferation and apoptosis;... Organism or Cell Type:
zebrafish Citation Extract: Suryawanshi H, Lalwani MK, Ramasamy S, Rana R, Scaria V, Sivasubbu S, Maiti S. Antagonism of microRNA Function in Zebrafish Embryos by Using Locked Nucleic Acid Enzymes (LNAzymes). ChemBioChem. 2012;[Epub ahead of print] doi:10.1002/cbic.201100789. |
Anti-sense morpholino oligonucleotide assay shows critical involvement for NF-kappaB activation in the production of Wnt-1 protein by HepG2 cells: oncology implications
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Citation:
J Biomed Sci. 2008 Sep;15(5):633-43. Epub 2008 May 7. Epub:
Not Epub Abstract:
The link of proto-oncogenic protein Wnt-1 production with NF-kappaB activation has been functionally demonstrated in PC12 cells... Citation Extract: Sun CS, Wu KT, Lee HH, Uen YH, Tian YF, Tzeng CC, Wang AH, Cheng CJ, Tsai SL. Anti-sense morpholino oligonucleotide assay shows critical involvement for NF-kappaB activation in the production of Wnt-1 protein by HepG2 cells: oncology implications. J Biomed Sci. 2008 Sep;15(5):633-43. Epub 2008 May 7.. |
Antihypertensive Actions of Moderate Hyperbilirubinemia: Role of Superoxide Inhibition
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Citation:
Am J Hypertens. 2013 Mar 12. [Epub ahead of print] doi: 10.1093/ajh/hpt038 Epub:
Not Epub Abstract:
BACKGROUND Moderate (approximately 2-fold) increases in plasma unconjugated bilirubin levels are able to attenuate the... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice C57BL/6J Citation Extract: Stec DE, Storm MV, Pruett BE, Gousset MU. Antihypertensive Actions of Moderate Hyperbilirubinemia: Role of Superoxide Inhibition. Am J Hypertens. 2013 Mar 12. [Epub ahead of print] doi: 10.1093/ajh/hpt038. |
Antisense modulation of RNA processing as a therapeutic approach in cancer therapy
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Citation:
Drug Discovery Today: Therapeutic Strategies. 2013;[Epub ahead of print] doi:10.1016/j.ddstr.2013.06.002 Epub:
Not Epub Abstract:
Next-generation antisense technologies are re-emerging as viable and powerful approaches to the treatment of several genetic... Citation Extract: Spraggon L, Cartegni L. Antisense modulation of RNA processing as a therapeutic approach in cancer therapy. Drug Discovery Today: Therapeutic Strategies. 2013;[Epub ahead of print] doi:10.1016/j.ddstr.2013.06.002. |
Antisense properties of morpholino oligomers
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Citation:
Nucleosides Nucleotides 1997;16(7-9): 889-898 Epub:
Not Epub Abstract:
Morpholino oligomers are third generation antisense agents designed to be cost effective, water soluble and resistant to... Citation Extract: Summerton J, Weller D. Antisense properties of morpholino oligomers. Nucleosides Nucleotides 1997;16(7-9): 889-898. |