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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

A combinatorial code of maternal GATA, Ets and beta-catenin-TCF transcription factors specifies and patterns the early ascidian ectoderm

Authors:
Rothbächer U, Bertrand V, Lamy C, Lemaire P
Citation:
Development. 2007 Nov;134(22):4023-32
Epub:
Not Epub
Abstract:
Our understanding of the maternal factors that initiate early chordate development, and of their direct zygotic targets, is...
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Rothbächer U, Bertrand V, Lamy C, Lemaire P. A combinatorial code of maternal GATA, Ets and beta-catenin-TCF transcription factors specifies and patterns the early ascidian ectoderm. Development. 2007 Nov;134(22):4023-32.

A Framework for the Establishment of a Cnidarian Gene Regulatory Network for “Endomesoderm” Specification: The Inputs of ß-Catenin/TCF Signaling

Authors:
Röttinger E, Dahlin P, Martindale MQ
Citation:
PLoS Genet. 2012;8(12):e1003164. doi:10.1371/journal.pgen.1003164
Epub:
Not Epub
Abstract:
Understanding the functional relationship between intracellular factors and extracellular signals is required for...
Delivery Method:
Microinjection
Organism or Cell Type:
Nematostella vectensis (cnidarian)
Citation Extract:
Röttinger E, Dahlin P, Martindale MQ. A Framework for the Establishment of a Cnidarian Gene Regulatory Network for “Endomesoderm” Specification: The Inputs of ß-Catenin/TCF Signaling. PLoS Genet. 2012;8(12):e1003164. doi:10.1371/journal.pgen.1003164.

A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease.

Authors:
Sadler KC, Amsterdam A, Soroka C, Boyer J, Hopkins N.
Citation:
Development. 2005 Aug;132(15):3561-72. Epub 2005 Jul 6.
Epub:
Not Epub
Abstract:
Hepatomegaly is a sign of many liver disorders. To identify zebrafish mutants to serve as models for hepatic pathologies, we...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sadler KC, Amsterdam A, Soroka C, Boyer J, Hopkins N.. A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease.. Development. 2005 Aug;132(15):3561-72. Epub 2005 Jul 6..

A Key Role for Poly(ADP-Ribose) Polymerase 3 in Ectodermal Specification and Neural Crest Development

Authors:
Rouleau M, Saxena V, Rodrigue A, Paquet ER, Gagnon A, Hendzel MJ, Masson J-Y, Ekker M, Poirier GG
Citation:
PLoS ONE. 2011;6(1):e15834. doi:10.1371/journal.pone.0015834
Epub:
Not Epub
Abstract:
Background The PARP family member poly(ADP-ribose) polymerase 3 (PARP3) is structurally related to the well characterized PARP1...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rouleau M, Saxena V, Rodrigue A, Paquet ER, Gagnon A, Hendzel MJ, Masson J-Y, Ekker M, Poirier GG. A Key Role for Poly(ADP-Ribose) Polymerase 3 in Ectodermal Specification and Neural Crest Development. PLoS ONE. 2011;6(1):e15834. doi:10.1371/journal.pone.0015834.

A Myc-Slug (Snail2)/Twist regulatory circuit directs vascular development

Authors:
Rodrigues CO, Nerlick ST, White EL, Cleveland JL, King ML
Citation:
Development. 2008 Jun;135(11):1903-11
Epub:
Not Epub
Abstract:
Myc-deficient mice fail to develop normal vascular networks and Myc-deficient embryonic stem cells fail to provoke a tumor...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Rodrigues CO, Nerlick ST, White EL, Cleveland JL, King ML. A Myc-Slug (Snail2)/Twist regulatory circuit directs vascular development. Development. 2008 Jun;135(11):1903-11.

A Xenopus tribbles orthologue is required for the progression of mitosis and for development of the nervous system

Authors:
Saka Y, Smith JC
Citation:
Dev Biol. 2004 Sep 15;273(2):210-25.
Epub:
Not Epub
Abstract:
The product of the Drosophila gene tribbles inhibits cell division in the ventral furrow of the embryo and thereby allows the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Saka Y, Smith JC. A Xenopus tribbles orthologue is required for the progression of mitosis and for development of the nervous system. Dev Biol. 2004 Sep 15;273(2):210-25..

An early Fgf signal required for gene expression in the zebrafish hindbrain primordium

Authors:
Roy NM, Sagerstrom CG
Citation:
Brain Res Dev Brain Res. 2004 Jan 31;148(1):27-42
Epub:
Not Epub
Abstract:
We have explored the role of fibroblast growth factor (Fgf) signaling in regulating gene expression in the early zebrafish...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roy NM, Sagerstrom CG. An early Fgf signal required for gene expression in the zebrafish hindbrain primordium. Brain Res Dev Brain Res. 2004 Jan 31;148(1):27-42.

Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development

Authors:
Sacilotto N, Monteiro R, Fritzsche M, Becker PW, Sanchez-del-Campo L, Liu K, Pinheiro P, Ratnayaka I, Davies B, Goding CR, Patient R, Bou-Gharios G, De Val S
Citation:
PNAS. 2013;[Epub ahead of print] doi:10.1073/pnas.1300805110
Epub:
Not Epub
Abstract:
The mechanisms by which arterial fate is established and maintained are not clearly understood. Although a number of signaling...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sacilotto N, Monteiro R, Fritzsche M, Becker PW, Sanchez-del-Campo L, Liu K, Pinheiro P, Ratnayaka I, Davies B, Goding CR, Patient R, Bou-Gharios G, De Val S. Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development. PNAS. 2013;[Epub ahead of print] doi:10.1073/pnas.1300805110 .

Antisense oligonucleotide treatment for a pseudoexon-generating mutation in the NPC1 gene causing Niemann-Pick type C disease

Authors:
Rodríguez-Pascau L, Coll MJ, Vilageliu L, Grinberg D
Citation:
Hum Mutat. 2009 Aug 30. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Niemann-Pick type C disease is an autosomal recessive disorder caused by mutations in either the NPC1 or NPC2 gene. While most...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human fibroblasts
Citation Extract:
Rodríguez-Pascau L, Coll MJ, Vilageliu L, Grinberg D. Antisense oligonucleotide treatment for a pseudoexon-generating mutation in the NPC1 gene causing Niemann-Pick type C disease. Hum Mutat. 2009 Aug 30. [Epub ahead of print].

Antisense PMO Found in Dystrophic Dog Model Was Effective in Cells from Exon 7-Deleted DMD Patient

Authors:
Saito T, Nakamura A, Aoki Y, Yokota T, Okada T, Osawa M, Takeda S
Citation:
PLoS ONE. 2010 Aug;5(8):e12239. doi:10.1371/journal.pone.0012239
Epub:
Not Epub
Abstract:
Background Antisense oligonucleotide-induced exon skipping is a promising approach for treatment of Duchenne muscular dystrophy...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: dog and human
Citation Extract:
Saito T, Nakamura A, Aoki Y, Yokota T, Okada T, Osawa M, Takeda S. Antisense PMO Found in Dystrophic Dog Model Was Effective in Cells from Exon 7-Deleted DMD Patient. PLoS ONE. 2010 Aug;5(8):e12239. doi:10.1371/journal.pone.0012239.

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