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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Knockdown of embryonic myosin heavy chain reveals an essential role in the morphology and function of the developing heart
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Citation:
Development. 2011 Sep;138(18):3955-66 Epub:
Not Epub Abstract:
The expression and function of embryonic myosin heavy chain (eMYH) has not been investigated within the early developing heart... Delivery Method:
pluronic gel Organism or Cell Type:
chick embryo Citation Extract: Rutland CS, Polo-Parada L, Ehler E, Alibhai A, Thorpe A, Suren S, Emes RD, Patel B, Loughna S. Knockdown of embryonic myosin heavy chain reveals an essential role in the morphology and function of the developing heart. Development. 2011 Sep;138(18):3955-66. |
Lef-1 and Tcf-3 transcription factors mediate tissue-specific Wnt signaling during Xenopus development
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Citation:
Curr Biol. 2002 Nov 19;12(22):1941-5 Epub:
Not Epub Abstract:
Wnt signaling functions repeatedly during embryonic development to induce different but specific responses. What molecular... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Roel G, Hamilton FS, Gent Y, Bain AA, Destree O, Hoppler S. Lef-1 and Tcf-3 transcription factors mediate tissue-specific Wnt signaling during Xenopus development. Curr Biol. 2002 Nov 19;12(22):1941-5. |
Maternal Interferon Regulatory Factor 6 is required for the differentiation of primary superficial epithelia in Danio and Xenopus embryos
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Citation:
Dev Biol. 2009 Jan 1;325(1):249-62. Epub 2008 Nov 5 Epub:
Not Epub Abstract:
Early in the development of animal embryos, superficial cells of the blastula form a distinct lineage and adopt an epithelial... Delivery Method:
Microinjection Organism or Cell Type:
Zebrafish and Xenopus laevis Citation Extract: Sabel JL, d'Alençon C, O'Brien EK, Van Otterloo E, Lutz K, Cuykendall TN, Schutte BC, Houston DW, Cornell RA. Maternal Interferon Regulatory Factor 6 is required for the differentiation of primary superficial epithelia in Danio and Xenopus embryos. Dev Biol. 2009 Jan 1;325(1):249-62. Epub 2008 Nov 5. |
MBD4 and MLH1 are required for apoptotic induction in xDNMT1-depleted embryos
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Citation:
Development. 2009 Jul;136(13):2277-86 Epub:
Not Epub Abstract:
Loss of the of the maintenance methyltransferase xDNMT1 during Xenopus development results in premature transcription and... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Ruzov A, Shorning B, Mortusewicz O, Dunican DS, Leonhardt H, Meehan RR. MBD4 and MLH1 are required for apoptotic induction in xDNMT1-depleted embryos. Development. 2009 Jul;136(13):2277-86. |
Melk-like kinase plays a role in hematopoiesis in the zebra fish
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Citation:
Mol Cell Biol. 2005 Aug;25(15):6682-93 Epub:
Not Epub Abstract:
A serine/threonine kinase, Melk, was initially cloned in mouse oocytes as a maternal gene, but whose function was unknown. In... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Saito R, Tabata Y, Muto A, Arai K, Watanabe S. Melk-like kinase plays a role in hematopoiesis in the zebra fish. Mol Cell Biol. 2005 Aug;25(15):6682-93. |
Microinjection of zebrafish embryos to analyze gene function
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Citation:
J Vis Exp. 2009 Mar 9;(25). pii: 1115. doi: 10.3791/1115. Epub:
Not Epub Abstract:
One of the advantages of studying zebrafish is the ease and speed of manipulating protein levels in the embryo. Morpholinos,... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Rosen JN, Sweeney MF, Mably JD. Microinjection of zebrafish embryos to analyze gene function. J Vis Exp. 2009 Mar 9;(25). pii: 1115. doi: 10.3791/1115.. |
Miz-1 is required to coordinate the expression of TCRbeta and p53 effector genes at the pre-TCR "beta-selection" checkpoint
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Citation:
J Immunol. 2011 Sep 15;187(6):2982-92. doi: 10.4049/jimmunol.1101451. Epub 2011 Aug 12. PMID: 21841135 Epub:
Not Epub Abstract:
Miz-1 is a Broad-complex, Tramtrack and Bric-à-brac/pox virus zinc finger domain (BTB/POZ)-containing protein expressed in... Citation Extract: Saba I, Kosan C, Vassen L, Klein-Hitpass L, Möröy T. Miz-1 is required to coordinate the expression of TCRbeta and p53 effector genes at the pre-TCR "beta-selection" checkpoint. J Immunol. 2011 Sep 15;187(6):2982-92. doi: 10.4049/jimmunol.1101451. Epub 2011 Aug 12. PMID: 21841135. |
Modulation of Tcf3 repressor complex composition regulates cdx4 expression in zebrafish
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Citation:
EMBO J. 2011 Jun 10;30(14):2894-907. doi: 10.1038/emboj.2011.184 Epub:
Not Epub Abstract:
The caudal homeobox (cdx) gene family is critical for specification of caudal body formation and erythropoiesis. In zebrafish,... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Ro H, Dawid IB. Modulation of Tcf3 repressor complex composition regulates cdx4 expression in zebrafish. EMBO J. 2011 Jun 10;30(14):2894-907. doi: 10.1038/emboj.2011.184. |
Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of α-dystroglycan
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Citation:
Nat Genet. 2012 Apr 22. doi: 10.1038/ng.2253. [Epub ahead of print] Epub:
Not Epub Abstract:
Walker-Warburg syndrome (WWS) is an autosomal recessive multisystem disorder characterized by complex eye and brain... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Roscioli T, Kamsteeg EJ, Buysse K, Maystadt I, van Reeuwijk J, van den Elzen C, van Beusekom E, Riemersma M, Pfundt R, Vissers LE, Schraders M, Altunoglu U, Buckley MF, Brunner HG, Grisart B, Zhou H, Veltman JA, Gilissen C, Mancini GM, Delrée P, Willemsen MA, Ramadža DP, Chitayat D, Bennett C, Sheridan E, Peeters EA, Tan-Sindhunata GM, de Die-Smulders CE, Devriendt K, Kayserili H, El-Hashash OA, Stemple DL, Lefeber DJ, Lin YY, van Bokhoven H. Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of α-dystroglycan. Nat Genet. 2012 Apr 22. doi: 10.1038/ng.2253. [Epub ahead of print]. |
Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome
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Citation:
Nat Genet. 2011 Jan 23. [Epub ahead of print] Epub:
Not Epub Abstract:
3MC syndrome has been proposed as a unifying term encompassing the overlapping Carnevale, Mingarelli, Malpuech and Michels... Organism or Cell Type:
zebrafish Citation Extract: Rooryck C, Diaz-Font A, Osborn DP, Chabchoub E, Hernandez-Hernandez V, Shamseldin H, Kenny J, Waters A, Jenkins D, Kaissi AA, Leal GF, Dallapiccola B, Carnevale F, Bitner-Glindzicz M, Lees M, Hennekam R, Stanier P, Burns AJ, Peeters H, Alkuraya FS, Beales. Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome. Nat Genet. 2011 Jan 23. [Epub ahead of print]. |