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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Linking planar polarity signalling to actomyosin contractility during vertebrate neurulation
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Citation:
Open Biol. 2024 Nov;14(11):240251. doi: 10.1098/rsob.240251. Epub 2024 Nov 20. PMID: 39561813; PMCID: PMC11576107 Epub:
Not Epub Abstract:
Actomyosin contractility represents an ancient feature of eukaryotic cells participating in many developmental and homeostasis... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Novotna S, Maia LA, Radaszkiewicz KA, Roudnicky P, Harnos J. Linking planar polarity signalling to actomyosin contractility during vertebrate neurulation. Open Biol. 2024 Nov;14(11):240251. doi: 10.1098/rsob.240251. Epub 2024 Nov 20. PMID: 39561813; PMCID: PMC11576107. |
Genetic inactivation of the β1 adrenergic receptor prevents cerebral cavernous malformations in zebrafish
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Citation:
Elife. 2025 Feb 24;13:RP99455. doi: 10.7554/eLife.99455. PMID: 39991834; PMCID: PMC11849999 Epub:
Not Epub Abstract:
Previously, we showed that propranolol reduces experimental murine cerebral cavernous malformations (CCMs) and prevents... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li W, McCurdy S, Lopez-Ramirez MA, Lee HS, Ginsberg MH. Genetic inactivation of the β1 adrenergic receptor prevents cerebral cavernous malformations in zebrafish. Elife. 2025 Feb 24;13:RP99455. doi: 10.7554/eLife.99455. PMID: 39991834; PMCID: PMC11849999. |
A Unified Phosphoramidite Platform for the Synthesis of Morpholino Oligonucleotides and Diverse Chimeric Backbones
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Citation:
J Am Chem Soc. 2024 Nov 19. doi: 10.1021/jacs.4c09510. Epub ahead of print. PMID: 39561294 Epub:
Not Epub Abstract:
Phosphorodiamidate Morpholino Oligonucleotides (PMOs) have been well established in the milieu of FDA-approved oligonucleotide-... Organism or Cell Type:
cell culture: Peripheral blood mononuclear cells (PBMCs) Citation Extract: Ghosh A, Banerjee A, Gupta S, Sinha S. A Unified Phosphoramidite Platform for the Synthesis of Morpholino Oligonucleotides and Diverse Chimeric Backbones. J Am Chem Soc. 2024 Nov 19. doi: 10.1021/jacs.4c09510. Epub ahead of print. PMID: 39561294. |
Identification of Eukaryotic Translation Initiation Factor 4B as a Novel Candidate Gene for Congenital Hypothyroidism
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Citation:
J Clin Endocrinol Metab. 2024 Nov 18;109(12):3282-3292. doi: 10.1210/clinem/dgae270. PMID: 38654471 Epub:
Not Epub Abstract:
Context
Congenital hypothyroidism (CH) is the most common endocrine disorder in neonates, but its etiology is still poorly... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun F, Zhang RJ, Fang Y, Yan CY, Zhang CR, Wu FY, Yang RM, Han B, Song HD, Zhao SX. Identification of Eukaryotic Translation Initiation Factor 4B as a Novel Candidate Gene for Congenital Hypothyroidism. J Clin Endocrinol Metab. 2024 Nov 18;109(12):3282-3292. doi: 10.1210/clinem/dgae270. PMID: 38654471. |
The role of ATP-binding Cassette subfamily B member 6 in the inner ear
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Citation:
Nat Commun. 2024 Nov 18;15(1):9885. doi: 10.1038/s41467-024-53663-x. PMID: 39557842; PMCID: PMC11574312 Epub:
Not Epub Abstract:
ABCB6 has been implicated in dyschromatosis universalis hereditaria, a condition characterized by hyperpigmented and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Baril SA, Wilson KA, Shaik MM, Fukuda Y, Umans RA, Barbieri A, Lynch J, Gose T, Myasnikov A, Oldham ML, Wang Y, Zhu J, Fang J, Zuo J, Kalathur RC, Ford RC, Coffin A, Taylor MR, O'Mara ML, Schuetz JD. The role of ATP-binding Cassette subfamily B member 6 in the inner ear. Nat Commun. 2024 Nov 18;15(1):9885. doi: 10.1038/s41467-024-53663-x. PMID: 39557842; PMCID: PMC11574312. |
Identification and functional characterization of CD209 homologous genes in zebrafish
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Citation:
Yi Chuan. 2024 Nov;46(11):947-957. doi: 10.16288/j.yczz.24-181. PMID: 39557479 Epub:
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Innate immune responses play a crucial role in maintaining homeostasis, their initiation closely related to pattern recognition... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang XJ, Huang ZH, Liu W, Zhang WQ, Huang ZB. Identification and functional characterization of CD209 homologous genes in zebrafish. Yi Chuan. 2024 Nov;46(11):947-957. doi: 10.16288/j.yczz.24-181. PMID: 39557479. |
Spatiotemporal requirements of nuclear β-catenin define early sea urchin embryogenesis
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Citation:
PLoS Biol. 2024 Nov 12;22(11):e3002880. doi: 10.1371/journal.pbio.3002880. Epub ahead of print. PMID: 39531468 Epub:
Not Epub Abstract:
Establishment of the 3 primordial germ layers (ectoderm, endoderm, and mesoderm) during early animal development represents an... Delivery Method:
microinjection; UV-photocleavable Morpholino Organism or Cell Type:
Paracentrotus lividus (sea urchin) Citation Extract: Lhomond G, Schubert M, Croce J. Spatiotemporal requirements of nuclear β-catenin define early sea urchin embryogenesis. PLoS Biol. 2024 Nov 12;22(11):e3002880. doi: 10.1371/journal.pbio.3002880. Epub ahead of print. PMID: 39531468. |
The nutrient sensor CRTC and Sarcalumenin/thinman represent an alternate pathway in cardiac hypertrophy
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Citation:
Cell Rep. 2024 Aug 27;43(8):114549. doi: 10.1016/j.celrep.2024.114549. Epub 2024 Aug 1. PMID: 39093699; PMCID: PMC11402474 Epub:
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CREB-regulated transcription co-activator (CRTC) is activated by Calcineurin (CaN) to regulate gluconeogenic genes. CaN also... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dondi C, Vogler G, Gupta A, Walls SM, Kervadec A, Marchant J, Romero MR, Diop S, Goode J, Thomas JB, Colas AR, Bodmer R, Montminy M, Ocorr K. The nutrient sensor CRTC and Sarcalumenin/thinman represent an alternate pathway in cardiac hypertrophy. Cell Rep. 2024 Aug 27;43(8):114549. doi: 10.1016/j.celrep.2024.114549. Epub 2024 Aug 1. PMID: 39093699; PMCID: PMC11402474. |
The heart is a resident tissue for hematopoietic stem and progenitor cells in zebrafish
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Citation:
Nat Commun. 2024 Aug 31;15(1):7589. doi: 10.1038/s41467-024-51920-7. PMID: 39217144; PMCID: PMC11366026 Epub:
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The contribution of endocardial cells (EdCs) to the hematopoietic lineages has been strongly debated. Here, we provide evidence... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bornhorst D, Hejjaji AV, Steuter L, Woodhead NM, Maier P, Gentile A, Alhajkadour A, Santis Larrain O, Weber M, Kikhi K, Guenther S, Huisken J, Tamplin OJ, Stainier DYR, Gunawan F. The heart is a resident tissue for hematopoietic stem and progenitor cells in zebrafish. Nat Commun. 2024 Aug 31;15(1):7589. doi: 10.1038/s41467-024-51920-7. PMID: 39217144; PMCID: PMC11366026. |
Sodium thiosulfate treatment rescues hyperglycaemia-induced pronephros damage in zebrafish by upregulating nitric oxide signalling
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Citation:
J Physiol. 2024 Sep 12. doi: 10.1113/JP286398. Epub ahead of print. PMID: 39264236 Epub:
Not Epub Abstract:
Sodium thiosulfate (STS) is gaining increasing attention in research for its potential therapeutic applications across a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ott H, Bennewitz K, Zhang X, Prianichnikova M, Sticht C, Poschet G, Kroll J. Sodium thiosulfate treatment rescues hyperglycaemia-induced pronephros damage in zebrafish by upregulating nitric oxide signalling. J Physiol. 2024 Sep 12. doi: 10.1113/JP286398. Epub ahead of print. PMID: 39264236. |