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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12165 scientific papers returned from the database with the search filters currently being used below.

Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42

Authors:
Hung IC, Chen TM, Lin JP, Tai YL, Shen TL, Lee SJ
Citation:
Open Biol. 2020 Feb;10(2):190273. doi: 10.1098/rsob.190273. Epub 2020 Feb 26
Epub:
Not Epub
Abstract:
Focal adhesion kinase (FAK) mediates vital cellular pathways during development. Despite its necessity, how FAK regulates and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hung IC, Chen TM, Lin JP, Tai YL, Shen TL, Lee SJ. Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42. Open Biol. 2020 Feb;10(2):190273. doi: 10.1098/rsob.190273. Epub 2020 Feb 26.

Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network

Authors:
Mukherjee S, Chaturvedi P, Rankin SA, Fish MB, Wlizla M, Paraiso KD, MacDonald M, Chen X, Weirauch MT, Blitz IL, Cho KW, Zorn AM
Citation:
Elife. 2020 Sep 7;9:e58029. doi: 10.7554/eLife.58029. PMID: 32894225; PMCID: PMC7498262
Epub:
Not Epub
Abstract:
Lineage specification is governed by gene regulatory networks (GRNs) that integrate the activity of signaling effectors and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis, Xenopus tropicalis
Citation Extract:
Mukherjee S, Chaturvedi P, Rankin SA, Fish MB, Wlizla M, Paraiso KD, MacDonald M, Chen X, Weirauch MT, Blitz IL, Cho KW, Zorn AM. Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network. Elife. 2020 Sep 7;9:e58029. doi: 10.7554/eLife.58029. PMID: 32894225; PMCID: PMC7498262.

Oocyte competence is maintained by m6A methyltransferase KIAA1429-mediated RNA metabolism during mouse follicular development

Authors:
Hu Y, Ouyang Z, Sui X, Qi M, Li M, He Y, Cao Y, Cao Q, Lu Q, Zhou S, Liu L, Liu L, Shen B, Shu W, Huo R
Citation:
Cell Death Differ. 2020;[Epub] doi:10.1038/s41418-020-0516-1
Epub:
Yes
Abstract:
KIAA1429 (also known as vir-like m6A methyltransferase-associated protein (VIRMA)), a newly identified component of the RNA m6A...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Hu Y, Ouyang Z, Sui X, Qi M, Li M, He Y, Cao Y, Cao Q, Lu Q, Zhou S, Liu L, Liu L, Shen B, Shu W, Huo R. Oocyte competence is maintained by m6A methyltransferase KIAA1429-mediated RNA metabolism during mouse follicular development. Cell Death Differ. 2020;[Epub] doi:10.1038/s41418-020-0516-1.

Identification of mecciRNAs and their roles in the mitochondrial entry of proteins

Authors:
Liu X, Wang X, Li J, Hu S, Deng Y, Yin H, Bao X, Zhang QC, Wang G, Wang B, Shi Q, Shan G
Citation:
Sci China Life Sci. 2020;[Epub ahead of print] doi:10.1007/s11427-020-1631-9
Epub:
Yes
Abstract:
Mammalian mitochondria have small genomes encoding very limited numbers of proteins. Over one thousand proteins and noncoding...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: 293T
Citation Extract:
Liu X, Wang X, Li J, Hu S, Deng Y, Yin H, Bao X, Zhang QC, Wang G, Wang B, Shi Q, Shan G. Identification of mecciRNAs and their roles in the mitochondrial entry of proteins. Sci China Life Sci. 2020;[Epub ahead of print] doi:10.1007/s11427-020-1631-9.

Transient receptor potential vanilloid 4 modulates ion balance through the isotocin pathway in zebrafish (Danio rerio)

Authors:
Liu ST, Chou MY, Wu LC, Horng JL, Lin LY
Citation:
Am J Physiol Regul Integr Comp Physiol. 2020;[Epub ahead of print] doi:10.1152/ajpregu.00307.2019
Epub:
Yes
Abstract:
Isotocin controls ion regulation through modulating the functions of ionocytes (also called mitochondria-rich cells or chloride...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu ST, Chou MY, Wu LC, Horng JL, Lin LY. Transient receptor potential vanilloid 4 modulates ion balance through the isotocin pathway in zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2020;[Epub ahead of print] doi:10.1152/ajpregu.00307.2019.

REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects

Authors:
Lee S-H, Hadipour-Lakmehsari S, Murthy HR, Gibb N, Miyake T, Teng ACT, Cosme J, Yu JC, Moon M, Lim SH, Wong V, Liu P, Billia F, Fernandez-Gonzalez R, Stagljar I, Sharma P, Kislinger T, Scott IC, Gramolini AO
Citation:
Nat Comm. 2020;11:965 doi:10.1038/s41467-019-14143-9
Epub:
Not Epub
Abstract:
The sarco-endoplasmic reticulum (SR/ER) plays an important role in the development and progression of many heart diseases....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee S-H, Hadipour-Lakmehsari S, Murthy HR, Gibb N, Miyake T, Teng ACT, Cosme J, Yu JC, Moon M, Lim SH, Wong V, Liu P, Billia F, Fernandez-Gonzalez R, Stagljar I, Sharma P, Kislinger T, Scott IC, Gramolini AO. REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects. Nat Comm. 2020;11:965 doi:10.1038/s41467-019-14143-9.

Axonal precursor miRNAs hitchhike on endosomes and locally regulate the development of neural circuits

Authors:
Corradi E, Dalla Costa I, Gavoci A, Iyer A, Roccuzzo M, Otto TA, Oliani E, Bridi S, Strohbuecker S, Santos-Rodriguez G, Valdembri D, Serini G, Abreu-Goodger C, Baudet ML
Citation:
EMBO J. 2020 Feb 19:e102513. doi: 10.15252/embj.2019102513. [Epub ahead of print]
Epub:
Yes
Abstract:
Various species of non‐coding RNAs (ncRNAs) are enriched in specific subcellular compartments, but the mechanisms orchestrating...
Delivery Method:
microinjection, electroporation
Organism or Cell Type:
Xenopus laevis embryo and cell culture
Citation Extract:
Corradi E, Dalla Costa I, Gavoci A, Iyer A, Roccuzzo M, Otto TA, Oliani E, Bridi S, Strohbuecker S, Santos-Rodriguez G, Valdembri D, Serini G, Abreu-Goodger C, Baudet ML. Axonal precursor miRNAs hitchhike on endosomes and locally regulate the development of neural circuits. EMBO J. 2020 Feb 19:e102513. doi: 10.15252/embj.2019102513. [Epub ahead of print].

Coordinated assembly and release of adhesions builds apical junctional belts during de novo polarisation of an epithelial tube

Authors:
Symonds AC, Buckley CE, Williams CA, Clarke JDW
Citation:
Development. 2020 Dec 23;147(24):dev191494. doi: 10.1242/dev.191494. PMID: 33361092; PMCID: PMC7774892
Epub:
Not Epub
Abstract:
Using the zebrafish neural tube as a model, we uncover the in vivo mechanisms allowing the generation of two opposing apical...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Symonds AC, Buckley CE, Williams CA, Clarke JDW. Coordinated assembly and release of adhesions builds apical junctional belts during de novo polarisation of an epithelial tube. Development. 2020 Dec 23;147(24):dev191494. doi: 10.1242/dev.191494. PMID: 33361092; PMCID: PMC7774892.

Targeting the unfolded protein response components differentially sensitizes breast tumors to doxorubicin while modulating chemotherapy-induced cardiotoxicities [abstract]

Authors:
Soto-Pantoja D, Clear K, Cook KL
Citation:
Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P5-14-19. doi:10.1158/1538-7445.SABCS19-P5-14-19
Epub:
Not Epub
Abstract:
Background: The unfolded protein response (UPR) is an endoplasmic reticulum pathway stimulated when the protein folding demand...
Organism or Cell Type:
mouse xenograft 4T1-luciferase triple negative breast cancer cells
Citation Extract:
Soto-Pantoja D, Clear K, Cook KL. Targeting the unfolded protein response components differentially sensitizes breast tumors to doxorubicin while modulating chemotherapy-induced cardiotoxicities [abstract]. Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P5-14-19. doi:10.1158/1538-7445.SABCS19-P5-14-19.

Diastereoselective Synthesis of Phosphorodiamidate Morpholino Dimers

Authors:
Min SJ, Kim NY, Chae HY, Chun KH
Citation:
Bull Korean Chem Soc. 2020. doi:10.1002/bkcs.11958
Epub:
Not Epub
Abstract:
No abstract available.
Citation Extract:
Min SJ, Kim NY, Chae HY, Chun KH. Diastereoselective Synthesis of Phosphorodiamidate Morpholino Dimers. Bull Korean Chem Soc. 2020. doi:10.1002/bkcs.11958.

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