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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12390 scientific papers returned from the database with the search filters currently being used below.

Morpholino-mediated gene knockdown in Mammalian organ culture

Authors:
Tufro A
Citation:
Methods Mol Biol. 2012;886:305-9
Epub:
Not Epub
Abstract:
We examined the role of semaphorin3a in ureteric bud (UB) branching morphogenesis using mouse metanephric organ culture [Tufro...
Citation Extract:
Tufro A. Morpholino-mediated gene knockdown in Mammalian organ culture. Methods Mol Biol. 2012;886:305-9.

Mutations in multidomain protein MEGF8 identify a Carpenter syndrome subtype associated with defective lateralization

Authors:
Twigg SR, Lloyd D, Jenkins D, Elçioglu NE, Cooper CD, Al-Sannaa N, Annagür A, Gillessen-Kaesbach G, Hüning I, Knight SJ, Goodship JA, Keavney BD, Beales PL, Gileadi O, McGowan SJ, Wilkie AO
Citation:
Am J Hum Genet. 2012 Nov 2;91(5):897-905. doi: 10.1016/j.ajhg.2012.08.027. Epub 2012 Oct 11
Epub:
Not Epub
Abstract:
Carpenter syndrome is an autosomal-recessive multiple-congenital-malformation disorder characterized by multisuture...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Twigg SR, Lloyd D, Jenkins D, Elçioglu NE, Cooper CD, Al-Sannaa N, Annagür A, Gillessen-Kaesbach G, Hüning I, Knight SJ, Goodship JA, Keavney BD, Beales PL, Gileadi O, McGowan SJ, Wilkie AO. Mutations in multidomain protein MEGF8 identify a Carpenter syndrome subtype associated with defective lateralization. Am J Hum Genet. 2012 Nov 2;91(5):897-905. doi: 10.1016/j.ajhg.2012.08.027. Epub 2012 Oct 11.

Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110

Authors:
Trede NS, Medenbach J, Damianov A, Hung LH, Weber GJ, Paw BH, Zhou Y, Hersey C, Zapata A, Keefe M, Barut BA, Stuart AB, Katz T, Amemiya CT, Zon LI, Bindereif A
Citation:
Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6608-13. Epub 2007 Apr 6
Epub:
Not Epub
Abstract:
The spliceosome cycle consists of assembly, catalysis, and recycling phases. Recycling of postspliceosomal U4 and U6 small...
Organism or Cell Type:
zebrafish
Citation Extract:
Trede NS, Medenbach J, Damianov A, Hung LH, Weber GJ, Paw BH, Zhou Y, Hersey C, Zapata A, Keefe M, Barut BA, Stuart AB, Katz T, Amemiya CT, Zon LI, Bindereif A. Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6608-13. Epub 2007 Apr 6.

Neural crest cells: a model for invasive behavior

Authors:
Tucker RP.
Citation:
Int J Biochem Cell Biol. 2004 Feb; 36(2): 173-7. Review.
Epub:
Not Epub
Abstract:
Neural crest cells are the embryonic precursors of the neurons and glia of the peripheral nervous system, pigment cells, and...
Delivery Method:
various
Organism or Cell Type:
various
Citation Extract:
Tucker RP.. Neural crest cells: a model for invasive behavior. Int J Biochem Cell Biol. 2004 Feb; 36(2): 173-7. Review..

Neurogenesis and neurite outgrowth in the spinal cord of chicken embryos and in primary cultures of spinal neurons following knockdown of Class III beta tubulin with antisense morpholinos

Authors:
Tucker RP, Tran H, Gong Q
Citation:
Protoplasma. 2008 Sep 30. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Microtubules are the primary cytoskeletal constituent of extending neurites. We used antisense morpholinos to knock down...
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Tucker RP, Tran H, Gong Q. Neurogenesis and neurite outgrowth in the spinal cord of chicken embryos and in primary cultures of spinal neurons following knockdown of Class III beta tubulin with antisense morpholinos. Protoplasma. 2008 Sep 30. [Epub ahead of print].

Ngs (notochord granular surface) encodes a novel type of intermediate filament family protein essential for notochord maintenance in zebrafish

Authors:
Tong X, Xia Z, Zu Y, Telfer H, Hu J, Yu J, Liu H, Zhang Q, Sodmergen D, Lin S, Zhang B
Citation:
J Biol Chem. 2012;[Epub ahead of print] doi:10.1074/jbc.M112.379172
Epub:
Not Epub
Abstract:
Notochord is an important organ involved in embryonic patterning and locomotion. In zebrafish, mature notochord consists of a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tong X, Xia Z, Zu Y, Telfer H, Hu J, Yu J, Liu H, Zhang Q, Sodmergen D, Lin S, Zhang B. Ngs (notochord granular surface) encodes a novel type of intermediate filament family protein essential for notochord maintenance in zebrafish. J Biol Chem. 2012;[Epub ahead of print] doi:10.1074/jbc.M112.379172.

Nkx2.7 and Nkx2.5 function redundantly and are required for cardiac morphogenesis of zebrafish embryos

Authors:
Tu CT, Yang TC, Tsai HJ
Citation:
PLoS ONE. 2009;4(1):e4249. Epub 2009 Jan 22
Epub:
Not Epub
Abstract:
BACKGROUND: Nkx2.7 is the tinman-related gene, as well as orthologs of Nkx2.5 and Nkx-2.3. Nkx2.7 and Nkx2.5 express in...
Organism or Cell Type:
zebrafish
Citation Extract:
Tu CT, Yang TC, Tsai HJ. Nkx2.7 and Nkx2.5 function redundantly and are required for cardiac morphogenesis of zebrafish embryos. PLoS ONE. 2009;4(1):e4249. Epub 2009 Jan 22.

Novel Targeting Of COX-2 pre-mRNA Using Antisense Morpholino Oligonucleotides Directed To The 3' Acceptor And 5' Donor Splice Sites Of Exon 4: Suppression Of COX-2 Activity In Human Amnion-Derived WISH And Myometrial Cells

Authors:
Tyson-Capper AJ, Europe-Finner GN
Citation:
Mol Pharmacol. 2006 Mar;69(3):796-804. Epub 2005 Dec 14.
Epub:
Not Epub
Abstract:
Increased expression of COX-2 has been implicated in the onset of both term and preterm labour. In this context both selective...
Delivery Method:
Endo-Porter and Special Delivery
Organism or Cell Type:
cell culture: human myometrial and WISH cells
Citation Extract:
Tyson-Capper AJ, Europe-Finner GN. Novel Targeting Of COX-2 pre-mRNA Using Antisense Morpholino Oligonucleotides Directed To The 3' Acceptor And 5' Donor Splice Sites Of Exon 4: Suppression Of COX-2 Activity In Human Amnion-Derived WISH And Myometrial Cells. Mol Pharmacol. 2006 Mar;69(3):796-804. Epub 2005 Dec 14..

Novel Targeting Of COX-2 pre-mRNA Using Antisense Morpholino Oligonucleotides: Suppression Of Cox-2 Activity In Human Myometrial cells And Amnion-Derived WISH Cells

Authors:
Tyson-Capper AJ, Europe-Finner GN
Citation:
FASEB J, Mar 2006; 20: A72
Epub:
Not Epub
Abstract:
Increased expression of COX-2 has been implicated in the onset of both term and preterm labour. In this context both selective...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human myometrial and WISH cells
Citation Extract:
Tyson-Capper AJ, Europe-Finner GN. Novel Targeting Of COX-2 pre-mRNA Using Antisense Morpholino Oligonucleotides: Suppression Of Cox-2 Activity In Human Myometrial cells And Amnion-Derived WISH Cells. FASEB J, Mar 2006; 20: A72.

Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK

Authors:
Unterseher F, Hefele JA, Giehl K, De Robertis EM, Wedlich D, Schambony A
Citation:
EMBO J. 2004 Aug 18;23(16):3259-69. Epub 2004 Aug 5
Epub:
Not Epub
Abstract:
Convergent extension movements occur ubiquitously in animal development. This special type of cell movement is controlled by...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Unterseher F, Hefele JA, Giehl K, De Robertis EM, Wedlich D, Schambony A. Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK. EMBO J. 2004 Aug 18;23(16):3259-69. Epub 2004 Aug 5.

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