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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12390 scientific papers returned from the database with the search filters currently being used below.

CYP1B1 knockdown does not alter synergistic developmental toxicity of polycyclic aromatic hydrocarbons in zebrafish (Danio rerio)

Authors:
Timme-Laragy AR, Noyes PD, Buhler DR, Di Giulio RT
Citation:
Mar Environ Res. 2008 Jul;66(1):85-7. Epub 2008 Feb 26.
Epub:
Not Epub
Abstract:
Polycyclic aromatic hydrocarbons (PAHs) are contaminants increasing in the environment largely due to burning of fossil fuels....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Timme-Laragy AR, Noyes PD, Buhler DR, Di Giulio RT. CYP1B1 knockdown does not alter synergistic developmental toxicity of polycyclic aromatic hydrocarbons in zebrafish (Danio rerio). Mar Environ Res. 2008 Jul;66(1):85-7. Epub 2008 Feb 26..

Death Receptors DR6 and TROY Regulate Brain Vascular Development

Authors:
Tam SJ, Richmond DL, Kaminker JS, Modrusan Z, Martin-McNulty B, Cao TC, Weimer RM, Carano RAD, van Bruggen N, Watts RJ
Citation:
Dev Cell. 2012;(22)2:403-417. doi:10.1016/j.devcel.2011.11.018
Epub:
Not Epub
Abstract:
Signaling events that regulate central nervous system (CNS) angiogenesis and blood-brain barrier (BBB) formation are only...
Organism or Cell Type:
zebrafish
Citation Extract:
Tam SJ, Richmond DL, Kaminker JS, Modrusan Z, Martin-McNulty B, Cao TC, Weimer RM, Carano RAD, van Bruggen N, Watts RJ. Death Receptors DR6 and TROY Regulate Brain Vascular Development. Dev Cell. 2012;(22)2:403-417. doi:10.1016/j.devcel.2011.11.018.

Def defines a conserved nucleolar pathway that leads p53 to proteasome-independent degradation

Authors:
Tao T, Shi H, Guan Y, Huang D, Chen Y, Lane DP, Chen J, Peng J
Citation:
Cell Res. 2013 May;23(5):620-34. doi: 10.1038/cr.2013.16. Epub 2013 Jan 29
Epub:
Not Epub
Abstract:
p53 protein turnover through the ubiquitination pathway is a vital mechanism in the regulation of its transcriptional activity...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tao T, Shi H, Guan Y, Huang D, Chen Y, Lane DP, Chen J, Peng J. Def defines a conserved nucleolar pathway that leads p53 to proteasome-independent degradation. Cell Res. 2013 May;23(5):620-34. doi: 10.1038/cr.2013.16. Epub 2013 Jan 29.

Developmental defects in a zebrafish model for muscular dystrophies associated with the loss of fukutin-related protein (FKRP)

Authors:
Thornhill P, Bassett D, Lochmüller H, Bushby K, Straub V
Citation:
Brain. 2008 Jun;131(Pt 6):1551-61. Epub 2008 May 13.
Epub:
Not Epub
Abstract:
A number of muscular dystrophies are associated with the defective glycosylation of alpha-dystroglycan and many are now known...
Organism or Cell Type:
zebrafish
Citation Extract:
Thornhill P, Bassett D, Lochmüller H, Bushby K, Straub V. Developmental defects in a zebrafish model for muscular dystrophies associated with the loss of fukutin-related protein (FKRP). Brain. 2008 Jun;131(Pt 6):1551-61. Epub 2008 May 13..

Differences in expression pattern and function between zebrafish hoxc13 orthologs: recruitment of Hoxc13b into an early embryonic role

Authors:
Thummel R, Li L, Tanase C, Sarras MP Jr, Godwin AR
Citation:
Dev Biol. 2004 Oct 15;274(2):318-33
Epub:
Not Epub
Abstract:
Vertebrate Hox genes are generally believed to initiate expression at the primitive streak or early neural plate stages. The...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thummel R, Li L, Tanase C, Sarras MP Jr, Godwin AR. Differences in expression pattern and function between zebrafish hoxc13 orthologs: recruitment of Hoxc13b into an early embryonic role. Dev Biol. 2004 Oct 15;274(2):318-33.

Dpysl2 (CRMP2) and Dpysl3 (CRMP4) phosphorylation by Cdk5 and DYRK2 is required for proper positioning of Rohon-Beard neurons and neural crest cells during neurulation in zebrafish

Authors:
Tanaka H, Morimura R, Ohshima T
Citation:
Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.07.032
Epub:
Not Epub
Abstract:
Dpysl2 (CRMP2) and Dpysl3 (CRMP4) are involved in neuronal polarity and axon elongation in cultured neurons. These proteins are...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tanaka H, Morimura R, Ohshima T. Dpysl2 (CRMP2) and Dpysl3 (CRMP4) phosphorylation by Cdk5 and DYRK2 is required for proper positioning of Rohon-Beard neurons and neural crest cells during neurulation in zebrafish. Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.07.032.

DYX1C1 is required for axonemal dynein assembly and ciliary motility

Authors:
Tarkar A, Loges NT, Slagle CE, Francis R, Dougherty GW, Tamayo JV, Shook B, Cantino M, Schwartz D, Jahnke C, Olbrich H, Werner C, Raidt J, Pennekamp P, Abouhamed M, Hjeij R, Köhler G, Griese M, Li Y, Lemke K, Klena N, Liu X, Gabriel G, Tobita K, Jaspers M, Morgan LC, Shapiro AJ, Letteboer SJ, Mans DA, Carson JL, Leigh MW, Wolf WE, Chen S, Lucas JS, Onoufriadis A, Plagnol V, Schmidts M, Boldt K; UK10K, Roepman R, Zariwala MA, Lo CW, Mitchison HM, Knowles MR, Burdine RD, Loturco JJ, Omran H
Citation:
Nat Genet. 2013 Jul 21. doi: 10.1038/ng.2707. [Epub ahead of print]
Epub:
Not Epub
Abstract:
DYX1C1 has been associated with dyslexia and neuronal migration in the developing neocortex. Unexpectedly, we found that...
Organism or Cell Type:
zebrafish
Citation Extract:
Tarkar A, Loges NT, Slagle CE, Francis R, Dougherty GW, Tamayo JV, Shook B, Cantino M, Schwartz D, Jahnke C, Olbrich H, Werner C, Raidt J, Pennekamp P, Abouhamed M, Hjeij R, Köhler G, Griese M, Li Y, Lemke K, Klena N, Liu X, Gabriel G, Tobita K, Jaspers M, Morgan LC, Shapiro AJ, Letteboer SJ, Mans DA, Carson JL, Leigh MW, Wolf WE, Chen S, Lucas JS, Onoufriadis A, Plagnol V, Schmidts M, Boldt K; UK10K, Roepman R, Zariwala MA, Lo CW, Mitchison HM, Knowles MR, Burdine RD, Loturco JJ, Omran H. DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat Genet. 2013 Jul 21. doi: 10.1038/ng.2707. [Epub ahead of print].

Effect of TNF-alpha antisense oligomers on cytokine production by primary murine alveolar macrophages.

Authors:
Taylor MF, Weller DD, Kobzik L
Citation:
Antisense Nucleic Acid Drug Dev 1998 Jun;8(3):199-205
Epub:
Not Epub
Abstract:
Antisense oligomers can inhibit expression of a single gene in a sequence-specific manner. As a result, these sequences are...
Delivery Method:
lipid-based
Organism or Cell Type:
cell culture: mouse primary alveolar macrophages
Citation Extract:
Taylor MF, Weller DD, Kobzik L. Effect of TNF-alpha antisense oligomers on cytokine production by primary murine alveolar macrophages.. Antisense Nucleic Acid Drug Dev 1998 Jun;8(3):199-205.

Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells

Authors:
Tian H, Mythreye K, Golzio C, Katsanis N, Blobe GC
Citation:
EMBO J. 2012 Oct 3;31(19):3885-900. doi: 10.1038/emboj.2012.246. Epub 2012 Aug 31
Epub:
Not Epub
Abstract:
Both the transforming growth factor β (TGF-β) and integrin signalling pathways have well-established roles in angiogenesis....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tian H, Mythreye K, Golzio C, Katsanis N, Blobe GC. Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells. EMBO J. 2012 Oct 3;31(19):3885-900. doi: 10.1038/emboj.2012.246. Epub 2012 Aug 31.

Erythropoiesis is regulated by the transcription elongation factor Foggy/Spt5 through gata1 gene regulation.

Authors:
Taneda T, Zhu W, Cao Q, Watanabe H, Yamaguchi Y, Handa H, Wada T
Citation:
Genes Cells 2011 Jan 4. doi: 10.1111/j.1365-2443.2010.01481.x. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Recent studies have showed that transcription elongation factors regulate early development. Foggy/Spt5 is a subunit of DRB...
Organism or Cell Type:
zebrafish
Citation Extract:
Taneda T, Zhu W, Cao Q, Watanabe H, Yamaguchi Y, Handa H, Wada T. Erythropoiesis is regulated by the transcription elongation factor Foggy/Spt5 through gata1 gene regulation.. Genes Cells 2011 Jan 4. doi: 10.1111/j.1365-2443.2010.01481.x. [Epub ahead of print].

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