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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

sall1 and sall4 repress pou5f3 family expression to allow neural patterning, differentiation, and morphogenesis in Xenopus laevis

Authors:
Exner CR, Kim AY, Mardjuki SM, Harland RM
Citation:
Dev Biol. 2017 Mar 18. pii: S0012-1606(16)30754-0. doi: 10.1016/j.ydbio.2017.03.015. [Epub ahead of print]
Epub:
Yes
Abstract:
The embryonic precursor of the vertebrate central nervous system, the neural plate, is patterned along the anterior-posterior...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Exner CR, Kim AY, Mardjuki SM, Harland RM. sall1 and sall4 repress pou5f3 family expression to allow neural patterning, differentiation, and morphogenesis in Xenopus laevis. Dev Biol. 2017 Mar 18. pii: S0012-1606(16)30754-0. doi: 10.1016/j.ydbio.2017.03.015. [Epub ahead of print].

Discovery of Novel Determinants of Endothelial Lineage using Chimeric Heterokaryons

Authors:
Wong WT, Matrone G, Tian XY, Tomoiaga SA, Au KF, Meng S, Yamazoe S, Sieveking D, Chen K, Burns DM, Chen JK, Blau HM, Cooke JP
Citation:
eLife. 2017; doi:10.7554/eLife.23588
Epub:
Not Epub
Abstract:
We wish to identify determinants of endothelial lineage. Murine embryonic stem cells (mESC) were fused with human endothelial...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wong WT, Matrone G, Tian XY, Tomoiaga SA, Au KF, Meng S, Yamazoe S, Sieveking D, Chen K, Burns DM, Chen JK, Blau HM, Cooke JP. Discovery of Novel Determinants of Endothelial Lineage using Chimeric Heterokaryons. eLife. 2017; doi:10.7554/eLife.23588.

Actomyosin-generated tension on cadherin is similar between dividing and non-dividing epithelial cells in early Xenopus laevis embryos

Authors:
Herbomel G, Hatte G, Roul J, Padilla-Parra S, Tassan J-P, Tramier M
Citation:
Sci Rep. 2017;7:45058 doi:10.1038/srep45058
Epub:
Not Epub
Abstract:
Epithelia represent a unique situation where polarized cells must maintain sufficiently strong cell-cell contacts to guarantee...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Herbomel G, Hatte G, Roul J, Padilla-Parra S, Tassan J-P, Tramier M. Actomyosin-generated tension on cadherin is similar between dividing and non-dividing epithelial cells in early Xenopus laevis embryos. Sci Rep. 2017;7:45058 doi:10.1038/srep45058.

Paxillin Genes and Actomyosin Contractility Regulate Myotome Morphogenesis in Zebrafish

Authors:
Jacob AE, Amack JD, Turner CE
Citation:
Dev Biol. 2017 Mar 14. pii: S0012-1606(16)30694-7. doi: 10.1016/j.ydbio.2017.03.012. [Epub ahead of print]
Epub:
Yes
Abstract:
Paxillin (Pxn) is a key adapter protein and signaling regulator at sites of cell-extracellular matrix (ECM) adhesion. Here, we...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jacob AE, Amack JD, Turner CE. Paxillin Genes and Actomyosin Contractility Regulate Myotome Morphogenesis in Zebrafish. Dev Biol. 2017 Mar 14. pii: S0012-1606(16)30694-7. doi: 10.1016/j.ydbio.2017.03.012. [Epub ahead of print].

Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine

Authors:
Xu J, Lu Z, Narayan A, Le Rouzic VP, Xu M, Hunkele A, Brown TG, Hoefer WF, Rossi GC, Rice RC, Martínez-Rivera A, Rajadhyaksha AM, Cartegni L, Bassoni DL, Pasternak GW, Pan Y-X
Citation:
J Clin Invest. 2017;[Epub ahead of print] doi:10.1172/JCI88760
Epub:
Yes
Abstract:
Extensive 3′ alternative splicing of the mu opioid receptor gene OPRM1 creates multiple C-terminal splice variants. However,...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse
Citation Extract:
Xu J, Lu Z, Narayan A, Le Rouzic VP, Xu M, Hunkele A, Brown TG, Hoefer WF, Rossi GC, Rice RC, Martínez-Rivera A, Rajadhyaksha AM, Cartegni L, Bassoni DL, Pasternak GW, Pan Y-X. Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine. J Clin Invest. 2017;[Epub ahead of print] doi:10.1172/JCI88760.

Cytoskeleton-associated protein 5 and clathrin heavy chain binding regulates spindle assembly in mouse oocytes

Authors:
Lu A, Zhou CJ, Wang DH, Han Z, Kong XW, Ma YZ, Yun ZZ, Liang CG
Citation:
Oncotarget. 2017 Feb 4. doi: 10.18632/oncotarget.15097. [Epub ahead of print]
Epub:
Yes
Abstract:
Mammalian oocyte meiotic maturation is the precondition of early embryo development. Lots of microtubules (MT)-associated...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Lu A, Zhou CJ, Wang DH, Han Z, Kong XW, Ma YZ, Yun ZZ, Liang CG. Cytoskeleton-associated protein 5 and clathrin heavy chain binding regulates spindle assembly in mouse oocytes. Oncotarget. 2017 Feb 4. doi: 10.18632/oncotarget.15097. [Epub ahead of print].

Systemic restoration of UBA1 ameliorates disease in spinal muscular atrophy

Authors:
Powis RA, Karyka E, Boyd P, Côme J, Jones RA, Zheng Y, Szunyogova E, Groen EJ, Hunter G, Thomson D, Wishart TM, Becker CG, Parson SH, Martinat C, Azzouz M, Gillingwater TH
Citation:
JCI Insight. 2016 Jul 21;1(11):e87908
Epub:
Not Epub
Abstract:
The autosomal recessive neuromuscular disease spinal muscular atrophy (SMA) is caused by loss of survival motor neuron (SMN)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Powis RA, Karyka E, Boyd P, Côme J, Jones RA, Zheng Y, Szunyogova E, Groen EJ, Hunter G, Thomson D, Wishart TM, Becker CG, Parson SH, Martinat C, Azzouz M, Gillingwater TH. Systemic restoration of UBA1 ameliorates disease in spinal muscular atrophy. JCI Insight. 2016 Jul 21;1(11):e87908.

c-Src Suppresses Dendritic Cell Antitumor Activity via T Cell Ig and Mucin Protein-3 Receptor

Authors:
Gujar R, Maurya N, Yadav V, Gupta M, Arora S, Khatri N, Sen P
Citation:
J Immunol. 2016 Sep 1;197(5):1650-62. doi: 10.4049/jimmunol.1600104
Epub:
Not Epub
Abstract:
The enhanced expression of T cell Ig and mucin protein-3 (TIM-3) on tumor-associated dendritic cells (DCs) attenuates antitumor...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice (B6 and BALB/c)
Citation Extract:
Gujar R, Maurya N, Yadav V, Gupta M, Arora S, Khatri N, Sen P. c-Src Suppresses Dendritic Cell Antitumor Activity via T Cell Ig and Mucin Protein-3 Receptor. J Immunol. 2016 Sep 1;197(5):1650-62. doi: 10.4049/jimmunol.1600104.

Annexin A6 controls neuronal membrane dynamics throughout chick cranial sensory gangliogenesis

Authors:
Shah A, Schiffmacher AT, Taneyhill LA
Citation:
Dev Biol. 2017;[Epub ahead of print] doi:10.1016/j.ydbio.2017.03.011
Epub:
Yes
Abstract:
Cranial sensory ganglia are components of the peripheral nervous system that possess a significant somatosensory role and...
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Shah A, Schiffmacher AT, Taneyhill LA. Annexin A6 controls neuronal membrane dynamics throughout chick cranial sensory gangliogenesis. Dev Biol. 2017;[Epub ahead of print] doi:10.1016/j.ydbio.2017.03.011.

Glutathione peroxidase 4 inhibits Wnt/β-catenin signaling and regulates dorsal organizer formation in zebrafish embryos

Authors:
Rong X, Zhou Y, Liu Y, Zhao B, Wang B, Wang C, Gong X, Tang P, Lu L, Li Y, Zhao C, Zhou J
Citation:
Development. 2017;[Epub ahead of print] doi:10.1242/dev.144261
Epub:
Yes
Abstract:
The Wnt/β-catenin signaling pathway plays pivotal roles in axis formation during embryogenesis and in adult tissue homeostasis...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rong X, Zhou Y, Liu Y, Zhao B, Wang B, Wang C, Gong X, Tang P, Lu L, Li Y, Zhao C, Zhou J. Glutathione peroxidase 4 inhibits Wnt/β-catenin signaling and regulates dorsal organizer formation in zebrafish embryos. Development. 2017;[Epub ahead of print] doi:10.1242/dev.144261.

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