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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

[OP.4D.01] Functional Analysis of Tmem63c in Zebrafish Reveals Its Role as a Novel Candidate for Albuminuria and Chronic Kidney Disease

Authors:
Kreutz R, Schulz A, Meyer AM, Lorenzen T, Stoll M, Panakova D
Citation:
J Hypertens. 2016 Sep;34 Suppl 2:e51. doi: 10.1097/01.hjh.0000491467.44896.76
Epub:
Not Epub
Abstract:
OBJECTIVE: The Munich Wistar Frömter (MWF) rat represents a rat model for chronic kidney disease (CKD) with the development of...
Organism or Cell Type:
zebrafish
Citation Extract:
Kreutz R, Schulz A, Meyer AM, Lorenzen T, Stoll M, Panakova D. [OP.4D.01] Functional Analysis of Tmem63c in Zebrafish Reveals Its Role as a Novel Candidate for Albuminuria and Chronic Kidney Disease. J Hypertens. 2016 Sep;34 Suppl 2:e51. doi: 10.1097/01.hjh.0000491467.44896.76.

Fragile X mental retardation protein knockdown in the developing Xenopus tadpole optic tectum results in enhanced feedforward inhibition and behavioral deficits

Authors:
Truszkowski TL, James EJ, Hasan M, Wishard TJ, Liu Z, Pratt KG, Cline HT, Aizenman CD
Citation:
Neural Dev. 2016 Aug 8;11(1):14. doi: 10.1186/s13064-016-0069-7
Epub:
Not Epub
Abstract:
BACKGROUND: Fragile X Syndrome is the leading monogenetic cause of autism and most common form of intellectual disability....
Delivery Method:
brain injection then electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Truszkowski TL, James EJ, Hasan M, Wishard TJ, Liu Z, Pratt KG, Cline HT, Aizenman CD. Fragile X mental retardation protein knockdown in the developing Xenopus tadpole optic tectum results in enhanced feedforward inhibition and behavioral deficits. Neural Dev. 2016 Aug 8;11(1):14. doi: 10.1186/s13064-016-0069-7.

Fis1 depletion in osteoarthritis impairs chondrocyte survival and peroxisomal and lysosomal function

Authors:
Kim D, Song J, Kang Y, Park S, Kim YI, Kwak S, Lim D, Park R, Chun CH, Choe SK, Jin EJ
Citation:
J Mol Med (Berl). 2016 Aug 6. [Epub ahead of print]
Epub:
Yes
Abstract:
Cumulative evidence suggests the importance of organelle homeostasis in regulating metabolic functions in response to various...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim D, Song J, Kang Y, Park S, Kim YI, Kwak S, Lim D, Park R, Chun CH, Choe SK, Jin EJ. Fis1 depletion in osteoarthritis impairs chondrocyte survival and peroxisomal and lysosomal function. J Mol Med (Berl). 2016 Aug 6. [Epub ahead of print].

Sec16 alternative splicing dynamically controls COPII transport efficiency

Authors:
Wilhelmi I, Kanski R, Neumann A, Herdt O, Hoff F, Jacob R, Preußner M, Heyd F
Citation:
Nat Commun. 2016 Aug 5;7:12347. doi: 10.1038/ncomms12347
Epub:
Not Epub
Abstract:
The transport of secretory proteins from the endoplasmic reticulum (ER) to the Golgi depends on COPII-coated vesicles. While...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: Hek293 and HeLa and human peripheral blood mononuclear cells (PBMCs) enriched for T cells
Citation Extract:
Wilhelmi I, Kanski R, Neumann A, Herdt O, Hoff F, Jacob R, Preußner M, Heyd F. Sec16 alternative splicing dynamically controls COPII transport efficiency. Nat Commun. 2016 Aug 5;7:12347. doi: 10.1038/ncomms12347.

Poly(ester amine) Composed of Polyethylenimine and Pluronic Enhance Delivery of Antisense Oligonucleotides In Vitro and in Dystrophic mdx Mice

Authors:
Wang M, Wu B, Tucker JD, Bollinger LE, Lu P, Lu Q
Citation:
Mol Ther Nucleic Acids. 2016 Aug 2;5(8):e341. doi: 10.1038/mtna.2016.51
Epub:
Not Epub
Abstract:
A series of poly(esteramine)s (PEAs) constructed from low molecular weight polyethyleneimine (LPEI) and Pluronic were evaluated...
Delivery Method:
Endo-Porter, Polyethylenimine and Pluronic (PEAs)
Organism or Cell Type:
cell culture: C2C12E50, mdx mice
Citation Extract:
Wang M, Wu B, Tucker JD, Bollinger LE, Lu P, Lu Q. Poly(ester amine) Composed of Polyethylenimine and Pluronic Enhance Delivery of Antisense Oligonucleotides In Vitro and in Dystrophic mdx Mice. Mol Ther Nucleic Acids. 2016 Aug 2;5(8):e341. doi: 10.1038/mtna.2016.51.

Recursive splicing in long vertebrate genes

Authors:
Sibley CR, Emmett W, Blazquez L, Faro A, Haberman N, Briese M, Trabzuni D, Ryten M, Weale ME, Hardy J, Modic M, Curk T, Wilson SW, Plagnol V, Ule J
Citation:
Nature. 2015 May 21;521(7552):371-5. doi:10.1038/nature14466
Epub:
Not Epub
Abstract:
It is generally believed that splicing removes introns as single units from precursor messenger RNA transcripts. However, some...
Delivery Method:
Endo-porter, microinjection
Organism or Cell Type:
SH-SY5Y cells, zebrafish
Citation Extract:
Sibley CR, Emmett W, Blazquez L, Faro A, Haberman N, Briese M, Trabzuni D, Ryten M, Weale ME, Hardy J, Modic M, Curk T, Wilson SW, Plagnol V, Ule J. Recursive splicing in long vertebrate genes. Nature. 2015 May 21;521(7552):371-5. doi:10.1038/nature14466.

GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1

Authors:
Velinder M, Singer J, Bareyan D, Meznarich J, Tracy CM, Fulcher JM, McClellan D, Lucente H, Franklin S, Sharma S, Engel ME
Citation:
Biochemical J. 2016;[Epub ahead of print] doi:10.1042/BCJ20160558
Epub:
Yes
Abstract:
Proper hematopoietic cell fate decisions require coordinated functions of transcription factors, their associated co-regulators...
Organism or Cell Type:
zebrafish
Citation Extract:
Velinder M, Singer J, Bareyan D, Meznarich J, Tracy CM, Fulcher JM, McClellan D, Lucente H, Franklin S, Sharma S, Engel ME. GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1. Biochemical J. 2016;[Epub ahead of print] doi:10.1042/BCJ20160558.

The endoderm indirectly influences morphogenetic movements of the zebrafish head kidney through the posterior cardinal vein and VegfC

Authors:
Chou CW, Hsu HC, You MS, Lin J, Liu YW
Citation:
Sci Rep. 2016 Aug 1;6:30677. doi: 10.1038/srep30677
Epub:
Not Epub
Abstract:
Integration of blood vessels and organ primordia determines organ shape and function. The head kidney in the zebrafish...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chou CW, Hsu HC, You MS, Lin J, Liu YW. The endoderm indirectly influences morphogenetic movements of the zebrafish head kidney through the posterior cardinal vein and VegfC. Sci Rep. 2016 Aug 1;6:30677. doi: 10.1038/srep30677.

The coiled-coil domain containing protein Ccdc136b antagonizes maternal Wnt/β-catenin activity during zebrafish dorsoventral axial patterning

Authors:
Wei S, Shang H, Cao Y, Wang Q
Citation:
J Genet Genomics. 2016 May 11. pii: S1673-8527(16)30051-0. doi: 10.1016/j.jgg.2016.05.003. [Epub ahead of print]
Epub:
Yes
Abstract:
The coiled-coil domain containing protein CCDC136 is a putative tumor suppressor and significantly down-regulated in gastric...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wei S, Shang H, Cao Y, Wang Q. The coiled-coil domain containing protein Ccdc136b antagonizes maternal Wnt/β-catenin activity during zebrafish dorsoventral axial patterning. J Genet Genomics. 2016 May 11. pii: S1673-8527(16)30051-0. doi: 10.1016/j.jgg.2016.05.003. [Epub ahead of print].

Smad4 is required for the development of cardiac and skeletal muscle in zebrafish

Authors:
Yang J, Wang J, Zeng Z, Qiao L, Zhuang L, Jiang L, Wei J, Ma Q, Wu M, Ye S, Gao Q, Ma D, Huang X
Citation:
Differentiation. 2016 Jul 28. pii: S0301-4681(15)30076-1. doi: 10.1016/j.diff.2016.06.005. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Transforming growth factor-beta (TGF-beta) regulates cellular functions and plays key roles in development and carcinogenesis....
Organism or Cell Type:
zebrafish
Citation Extract:
Yang J, Wang J, Zeng Z, Qiao L, Zhuang L, Jiang L, Wei J, Ma Q, Wu M, Ye S, Gao Q, Ma D, Huang X. Smad4 is required for the development of cardiac and skeletal muscle in zebrafish. Differentiation. 2016 Jul 28. pii: S0301-4681(15)30076-1. doi: 10.1016/j.diff.2016.06.005. [Epub ahead of print].

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