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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Foxa2 and Hif1ab regulate maturation of intestinal goblet cells by modulating agr2 expression in zebrafish embryos

Authors:
Lai YR, Lu YF, Lien HW, Huang CJ, Hwang SL
Citation:
Biochem J. 2016 May 24. pii: BCJ20160392. [Epub ahead of print]
Epub:
Yes
Abstract:
Mammalian anterior gradient 2 (AGR2), an endoplasmic reticulum protein disulfide isomerase, is involved in cancer cell growth...
Link:
http://www.biochemj.org/content/early/2016/05/24/BCJ20160392
Organism or Cell Type:
zebrafish
Citation Extract:
Lai YR, Lu YF, Lien HW, Huang CJ, Hwang SL. Foxa2 and Hif1ab regulate maturation of intestinal goblet cells by modulating agr2 expression in zebrafish embryos. Biochem J. 2016 May 24. pii: BCJ20160392. [Epub ahead of print].

Solid-phase-supported synthesis of morpholino-glycine oligonucleotide mimics.

Authors:
Abramova TV, Belov SS, Tarasenko YV, Silnikov VN
Citation:
Beilstein J Org Chem. 2014;10:1151-8. doi:10.3762/bjoc.10.115
Epub:
Not Epub
Abstract:
Efficient solid phase supported peptide synthesis (SPPS) of morpholino glycine oligonucleotide (MorGLy) mimics has been...
Link:
http://www.beilstein-journals.org/bjoc/single/articleFullText.htm?publicId=1860-5397-10-115
Citation Extract:
Abramova TV, Belov SS, Tarasenko YV, Silnikov VN. Solid-phase-supported synthesis of morpholino-glycine oligonucleotide mimics.. Beilstein J Org Chem. 2014;10:1151-8. doi:10.3762/bjoc.10.115.

Development of the aboral domain in Nematostella requires β-catenin and the opposing activities of Six3/6 and Frizzled5/8

Authors:
Leclère L, Bause M, Sinigaglia C, Steger J, Rentzsch F
Citation:
Development. 2016;143:1766-1777. doi: 10.1242/dev.120931
Epub:
Not Epub
Abstract:
The development of the oral pole in cnidarians and the posterior pole in bilaterians is regulated by canonical Wnt signaling,...
Link:
http://dev.biologists.org/content/143/10/1766
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Leclère L, Bause M, Sinigaglia C, Steger J, Rentzsch F. Development of the aboral domain in Nematostella requires β-catenin and the opposing activities of Six3/6 and Frizzled5/8. Development. 2016;143:1766-1777. doi: 10.1242/dev.120931 .

klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis

Authors:
Steed E, Faggianelli N, Roth S, Ramspacher C, Concordet J-P, Vermot J
Citation:
Nat Comm. 2016;7:11646. doi:10.1038/ncomms11646
Epub:
Not Epub
Abstract:
The heartbeat and blood flow signal to endocardial cell progenitors through mechanosensitive proteins that modulate the genetic...
Link:
http://www.nature.com/ncomms/2016/160525/ncomms11646/full/ncomms11646.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Steed E, Faggianelli N, Roth S, Ramspacher C, Concordet J-P, Vermot J. klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis. Nat Comm. 2016;7:11646. doi:10.1038/ncomms11646.

The polycystin complex mediates Wnt/Ca2+ signalling

Authors:
Kim S, Nie H, Nesin V, Tran U, Outeda P, Bai CX, Keeling J, Maskey D, Watnick T, Wessely O, Tsiokas L
Citation:
Nat Cell Biol. 2016 May 23. doi: 10.1038/ncb3363. [Epub ahead of print]
Epub:
Yes
Abstract:
WNT ligands induce Ca2+ signalling on target cells. PKD1 (polycystin 1) is considered an orphan, atypical G-protein-coupled...
Link:
http://www.nature.com/ncb/journal/vaop/ncurrent/full/ncb3363.html
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kim S, Nie H, Nesin V, Tran U, Outeda P, Bai CX, Keeling J, Maskey D, Watnick T, Wessely O, Tsiokas L. The polycystin complex mediates Wnt/Ca2+ signalling. Nat Cell Biol. 2016 May 23. doi: 10.1038/ncb3363. [Epub ahead of print].

Open and closed evolutionary paths for drastic morphological changes, involving serial gene duplication, sub-functionalization, and selection

Authors:
Abe G, Lee S-H, Li I-J, Chang C-J, Tamura K,Ota KG
Citation:
Sci Rep. 2016;6:26838. doi:10.1038/srep26838
Epub:
Not Epub
Abstract:
Twin-tail goldfish strains are examples of drastic morphological alterations that emerged through domestication. Although this...
Link:
http://www.nature.com/articles/srep26838
Delivery Method:
microinjection
Organism or Cell Type:
Carassius auratus (goldfish), Cyprinus carpio (common carp)
Citation Extract:
Abe G, Lee S-H, Li I-J, Chang C-J, Tamura K,Ota KG. Open and closed evolutionary paths for drastic morphological changes, involving serial gene duplication, sub-functionalization, and selection. Sci Rep. 2016;6:26838. doi:10.1038/srep26838.

NANS-mediated synthesis of sialic acid is required for brain and skeletal development

Authors:
van Karnebeek CD, Bonafé L, Wen XY, Tarailo-Graovac M, Balzano S, Royer-Bertrand B, Ashikov A, Garavelli L, Mammi I, Turolla L, Breen C, Donnai D, Cormier V, Heron D, Nishimura G, Uchikawa S, Campos-Xavier B, Rossi A, Hennet T, Brand-Arzamendi K, Rozmus J, Harshman K, Stevenson BJ, Girardi E, Superti-Furga G, Dewan T, Collingridge A, Halparin J, Ross CJ, Van Allen MI, Rossi A, Engelke UF, Kluijtmans LA, van der Heeft E, Renkema H, de Brouwer A, Huijben K, Zijlstra F, Heisse T, Boltje T, Wasserman WW, Rivolta C, Unger S, Lefeber DJ, Wevers RA, Superti-Furga A
Citation:
Nat Genet. 2016 May 23. doi: 10.1038/ng.3578. [Epub ahead of print]
Epub:
Yes
Abstract:
We identified biallelic mutations in NANS, the gene encoding the synthase for N-acetylneuraminic acid (NeuNAc; sialic acid), in...
Link:
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3578.html
Organism or Cell Type:
zebrafish
Citation Extract:
van Karnebeek CD, Bonafé L, Wen XY, Tarailo-Graovac M, Balzano S, Royer-Bertrand B, Ashikov A, Garavelli L, Mammi I, Turolla L, Breen C, Donnai D, Cormier V, Heron D, Nishimura G, Uchikawa S, Campos-Xavier B, Rossi A, Hennet T, Brand-Arzamendi K, Rozmus J, Harshman K, Stevenson BJ, Girardi E, Superti-Furga G, Dewan T, Collingridge A, Halparin J, Ross CJ, Van Allen MI, Rossi A, Engelke UF, Kluijtmans LA, van der Heeft E, Renkema H, de Brouwer A, Huijben K, Zijlstra F, Heisse T, Boltje T, Wasserman WW, Rivolta C, Unger S, Lefeber DJ, Wevers RA, Superti-Furga A. NANS-mediated synthesis of sialic acid is required for brain and skeletal development. Nat Genet. 2016 May 23. doi: 10.1038/ng.3578. [Epub ahead of print].

Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish

Authors:
Giacomotto J, Carroll AP, Rinkwitz S, Mowry B, Cairns MJ, Becker TS
Citation:
Transl Psychiatry. 2016 May 24;6:e818. doi: 10.1038/tp.2016.88
Epub:
Not Epub
Abstract:
The neurodevelopmentally regulated microRNA miR-137 was strongly implicated as risk locus for schizophrenia in the most recent...
Link:
http://www.nature.com/tp/journal/v6/n5/full/tp201688a.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Giacomotto J, Carroll AP, Rinkwitz S, Mowry B, Cairns MJ, Becker TS. Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish. Transl Psychiatry. 2016 May 24;6:e818. doi: 10.1038/tp.2016.88.

The cardiac-restricted protein ADP-ribosylhydrolase-like 1 is essential for heart chamber outgrowth and acts on muscle actin filament assembly

Authors:
Smith SJ, Towers N, Saldanha JW, Shang CA, Mahmood SR, Taylor WR, Mohun TJ
Citation:
Dev Biol. 2016 May 20. pii: S0012-1606(15)30138-X. doi: 10.1016/j.ydbio.2016.05.006. [Epub ahead of print]
Epub:
Yes
Abstract:
Adprhl1, a member of the ADP-ribosylhydrolase protein family, is expressed exclusively in the developing heart of all...
Link:
http://www.sciencedirect.com/science/article/pii/S001216061530138X
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Smith SJ, Towers N, Saldanha JW, Shang CA, Mahmood SR, Taylor WR, Mohun TJ. The cardiac-restricted protein ADP-ribosylhydrolase-like 1 is essential for heart chamber outgrowth and acts on muscle actin filament assembly. Dev Biol. 2016 May 20. pii: S0012-1606(15)30138-X. doi: 10.1016/j.ydbio.2016.05.006. [Epub ahead of print].

Embryonic cardiotoxicity of weak aryl hydrocarbon receptor agonists and cyp1a inhibitor fluoranthene in the Atlantic killifish (Fundulus heteroclitus)

Authors:
Brown DR, Clark BW, Garner LV, Di Giulio RT
Citation:
Comp Biochem Physiol C Toxicol Pharmacol. 2016 May 20. pii: S1532-0456(16)30062-X. doi: 10.1016/j.cbpc.2016.05.005. [Epub ahead of print]
Epub:
Not Epub
Abstract:
High affinity aryl hydrocarbon receptor (AHR) ligands, such as certain polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo...
Link:
http://www.sciencedirect.com/science/article/pii/S153204561630062X
Delivery Method:
microinjection
Organism or Cell Type:
Fundulus heteroclitus (killifish)
Citation Extract:
Brown DR, Clark BW, Garner LV, Di Giulio RT. Embryonic cardiotoxicity of weak aryl hydrocarbon receptor agonists and cyp1a inhibitor fluoranthene in the Atlantic killifish (Fundulus heteroclitus). Comp Biochem Physiol C Toxicol Pharmacol. 2016 May 20. pii: S1532-0456(16)30062-X. doi: 10.1016/j.cbpc.2016.05.005. [Epub ahead of print].

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