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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12367 scientific papers returned from the database with the search filters currently being used below.
There are 12367 scientific papers returned from the database with the search filters currently being used below.
Open reading frame correction using splice-switching antisense oligonucleotides for the treatment of cystic fibrosis
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Citation:
Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2114886119. doi: 10.1073/pnas.2114886119 Epub:
Not Epub Abstract:
CFTR gene mutations that result in the introduction of premature termination codons (PTCs) are common in cystic fibrosis (CF).... Delivery Method:
Endo-Porter, osmotic shock Organism or Cell Type:
cell culture: CFF16hBEge-W1282X-SCC:3F2, primary hBE Citation Extract: Michaels WE, Pena-Rasgado C, Kotaria R, Bridges RJ, Hastings ML. Open reading frame correction using splice-switching antisense oligonucleotides for the treatment of cystic fibrosis. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2114886119. doi: 10.1073/pnas.2114886119. |
Evolutionary distinct roles of γ-secretase subunit nicastrin in zebrafish and humans
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Citation:
J Dermatol Sci. 2022 Jan 5:S0923-1811(22)00001-9. doi: 10.1016/j.jdermsci.2022.01.001. Online ahead of print Epub:
Yes Abstract:
Background: Mutations in the genes that encode the human γ-secretase subunits Presenilin-1, Presenilin Enhancer Protein 2, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hermasch MA, Janning H, Perera RP, Schnabel V, Rostam N, Ramos-Gomes F, Muschalek W, Bennemann A, Alves F, Ralser DJ, Betz RC, Schön MP, Dosch R, Frank J. Evolutionary distinct roles of γ-secretase subunit nicastrin in zebrafish and humans. J Dermatol Sci. 2022 Jan 5:S0923-1811(22)00001-9. doi: 10.1016/j.jdermsci.2022.01.001. Online ahead of print. |
In Vivo Modeling of Zebrafish Zinc Finger, MIZ-Type Containing 1 (ZMIZ1) Expression and its Effect on Pigmentation
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Citation:
International journal of dermatology and venereology 2021;[Epub] doi:10.1097/JD9.0000000000000150 Epub:
Yes Abstract:
Objective: We conducted this study to investigate the role of Zinc Finger MIZ-Type Containing 1 (ZMIZ1) in pigmentation remains... Link:
Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun Y, Liu T, Mi Z, Wang C, Sun L, Ge K, Sheng D, Liu H, Zhang F. In Vivo Modeling of Zebrafish Zinc Finger, MIZ-Type Containing 1 (ZMIZ1) Expression and its Effect on Pigmentation. International journal of dermatology and venereology 2021;[Epub] doi:10.1097/JD9.0000000000000150. |
Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression
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Citation:
Cell Death Differ. 2022 Jan 1. doi: 10.1038/s41418-021-00915-8. Online ahead of print Epub:
Yes Abstract:
Olig2 is indispensable for motoneuron and oligodendrocyte fate-specification in the pMN domain of embryonic spinal cords, and... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mouse embryo E14.5 Citation Extract: Bizen N, Bepari AK, Zhou L, Abe M, Sakimura K, Ono K, Takebayashi H. Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression. Cell Death Differ. 2022 Jan 1. doi: 10.1038/s41418-021-00915-8. Online ahead of print. |
Zebrafish Vascular Quantification (ZVQ): a tool for quantification of three-dimensional zebrafish cerebrovascular architecture by automated image analysis
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Citation:
Development. 2022 Jan 10:dev.199720. doi: 10.1242/dev.199720. Online ahead of print Epub:
Yes Abstract:
Zebrafish transgenic lines and light sheet fluorescence microscopy allow in-depth insights into three-dimensional vascular... Organism or Cell Type:
zebrafish Citation Extract: Kugler EC, Frost J, Silva V, Plant K, Chhabria K, Chico TJA, Armitage PA. Zebrafish Vascular Quantification (ZVQ): a tool for quantification of three-dimensional zebrafish cerebrovascular architecture by automated image analysis. Development. 2022 Jan 10:dev.199720. doi: 10.1242/dev.199720. Online ahead of print. |
Transcriptome analysis of the early stage ifnlr1-mutant zebrafish indicates the immune response to auditory dysfunction
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Citation:
Gene Expr Patterns. 2021 Dec 27;43:119229. doi: 10.1016/j.gep.2021.119229. Online ahead of print Epub:
Not Epub Abstract:
Background: IFNLR1 has been recently identified to be related to autosomal dominant nonsyndromic sensorineural hearing loss (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang WQ, Qiu SW, Huang SS, Wang GJ, Han MY, Kang DY, Yuan YY, Gao X, Dai P. Transcriptome analysis of the early stage ifnlr1-mutant zebrafish indicates the immune response to auditory dysfunction. Gene Expr Patterns. 2021 Dec 27;43:119229. doi: 10.1016/j.gep.2021.119229. Online ahead of print. |
An efficient miRNA knockout approach using CRISPR-Cas9 in Xenopus
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Citation:
Dev Biol. 2021 Dec 27:S0012-1606(21)00260-8. doi: 10.1016/j.ydbio.2021.12.015. Online ahead of print Epub:
Yes Abstract:
In recent years CRISPR-Cas9 knockouts (KO) have become increasingly ultilised to study gene function. MicroRNAs (miRNAs) are... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Godden AM, Antonaci M, Ward NJ, van der Lee M, Abu-Daya A, Guille M, Wheeler GN. An efficient miRNA knockout approach using CRISPR-Cas9 in Xenopus. Dev Biol. 2021 Dec 27:S0012-1606(21)00260-8. doi: 10.1016/j.ydbio.2021.12.015. Online ahead of print. |
Delta/Jagged-mediated Notch signaling induces the differentiation of agr2-positive epidermal mucous cells in zebrafish embryos
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Citation:
PLoS Genet. 2021 Dec 28;17(12):e1009969. doi: 10.1371/journal.pgen.1009969. Online ahead of print Epub:
Not Epub Abstract:
Teleosts live in aquatic habitats, where they encounter ionic and acid-base fluctuations as well as infectious pathogens. To... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lu YF, Liu DW, Li IC, Lin J, Wang CM, Chu KC, Kuo HH, Lin CY, Yih LH, Jiang YJ, Hwang SL. Delta/Jagged-mediated Notch signaling induces the differentiation of agr2-positive epidermal mucous cells in zebrafish embryos. PLoS Genet. 2021 Dec 28;17(12):e1009969. doi: 10.1371/journal.pgen.1009969. Online ahead of print. |
A splice site mutation in the TSEN2 causes a new syndrome with craniofacial and central nervous system malformations, and atypical hemolytic uremic syndrome
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Citation:
Clin Genet. 2021 Dec 28. doi: 10.1111/cge.14105. Online ahead of print Epub:
Yes Abstract:
Recessive mutations in the genes encoding the four subunits of the tRNA splicing endonuclease complex (TSEN54, TSEN34, TSEN15,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Canpolat N, Liu D, Atayar E, Saygili S, Kara NS, Westfall TA, Ding Q, Brown BJ, Braun TA, Slusarski D, Oguz KK, Ozluk Y, Tuysuz B, Tastemel Ozturk T, Sever L, Sezerman OU, Topaloglu R, Caliskan S, Attanasio M, Ozaltin F. A splice site mutation in the TSEN2 causes a new syndrome with craniofacial and central nervous system malformations, and atypical hemolytic uremic syndrome. Clin Genet. 2021 Dec 28. doi: 10.1111/cge.14105. Online ahead of print. |
Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling
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Citation:
Development. 2016 Nov 1;143(21):3944-3955. doi: 10.1242/dev.138917. Epub 2016 Sep 15 Epub:
Not Epub Abstract:
Hedgehog (Hh) signaling is fundamentally important for development and adult tissue homeostasis. It is well established that in... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Jin Z, Schwend T, Fu J, Bao Z, Liang J, Zhao H, Mei W, Yang J. Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling. Development. 2016 Nov 1;143(21):3944-3955. doi: 10.1242/dev.138917. Epub 2016 Sep 15. |