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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12221 scientific papers returned from the database with the search filters currently being used below.

Tbx5a and Tbx5b paralogues act in combination to control separate vectors of migration in the fin field of zebrafish

Authors:
Anderson EB, Mao Q, Ho RK
Citation:
Dev Biol. 2021 Oct 28:S0012-1606(21)00231-1. doi: 10.1016/j.ydbio.2021.10.008. Online ahead of print
Epub:
Yes
Abstract:
The T-box containing family member, TBX5, has been shown to play important functional roles in the pectoral appendages of a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Anderson EB, Mao Q, Ho RK. Tbx5a and Tbx5b paralogues act in combination to control separate vectors of migration in the fin field of zebrafish. Dev Biol. 2021 Oct 28:S0012-1606(21)00231-1. doi: 10.1016/j.ydbio.2021.10.008. Online ahead of print.

The RNA helicase Ddx21 controls Vegfc-driven developmental lymphangiogenesis by balancing endothelial cell ribosome biogenesis and p53 function

Authors:
Koltowska K, Okuda KS, Gloger M, Rondon-Galeano M, Mason E, Xuan J, Dudczig S, Chen H, Arnold H, Skoczylas R, Bower NI, Paterson S, Lagendijk AK, Baillie GJ,Leshchiner I, Simons C, Smith KA, Goessling W, Heath JK, Pearson RB, Sanij E, Schulte-Merker S, Hogan BM
Citation:
Nat Cell Biol. 2021;23(11):1136-47. doi:10.1038/s41556-021-00784-w
Epub:
Not Epub
Abstract:
The development of a functional vasculature requires the coordinated control of cell fate, lineage differentiation and network...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Koltowska K, Okuda KS, Gloger M, Rondon-Galeano M, Mason E, Xuan J, Dudczig S, Chen H, Arnold H, Skoczylas R, Bower NI, Paterson S, Lagendijk AK, Baillie GJ,Leshchiner I, Simons C, Smith KA, Goessling W, Heath JK, Pearson RB, Sanij E, Schulte-Merker S, Hogan BM. The RNA helicase Ddx21 controls Vegfc-driven developmental lymphangiogenesis by balancing endothelial cell ribosome biogenesis and p53 function. Nat Cell Biol. 2021;23(11):1136-47. doi:10.1038/s41556-021-00784-w.

MT1 but not MT2 melatonin receptor knockout decreases biliary damage and liver fibrosis during cholestatic liver injury

Authors:
Wu N, Carpino G, Ceci L, Baiocchi L, Francis H, Kennedy L, Zhou T, Chen L, Sato K, Kyritsi K, Meadows V, Ekser B, Franchitto A, Mancinelli R, Onori P, Gaudio E, Glaser S, Alpini G
Citation:
Hepatology. 2021 Nov 7. doi: 10.1002/hep.32233. Online ahead of print
Epub:
Yes
Abstract:
Background & aims: Melatonin reduces biliary damage and liver fibrosis in cholestatic models by interaction with melatonin...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Wu N, Carpino G, Ceci L, Baiocchi L, Francis H, Kennedy L, Zhou T, Chen L, Sato K, Kyritsi K, Meadows V, Ekser B, Franchitto A, Mancinelli R, Onori P, Gaudio E, Glaser S, Alpini G. MT1 but not MT2 melatonin receptor knockout decreases biliary damage and liver fibrosis during cholestatic liver injury. Hepatology. 2021 Nov 7. doi: 10.1002/hep.32233. Online ahead of print.

Proper Balance of Small GTPase rab10 Is Critical for PGC Migration in Zebrafish

Authors:
Mo C, Li W, Jia K, Liu W, Yi M
Citation:
Int J Mol Sci. 2021;22(21):11962. doi:10.3390/ijms222111962
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) play important roles in post−transcriptional repression in nearly every biological process including germ...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mo C, Li W, Jia K, Liu W, Yi M. Proper Balance of Small GTPase rab10 Is Critical for PGC Migration in Zebrafish. Int J Mol Sci. 2021;22(21):11962. doi:10.3390/ijms222111962.

Polarized Dishevelled dissolution and reassembly drives embryonic axis specification in sea star oocytes

Authors:
Swartz SZ, Tan TH, Perillo M, Fakhri N, Wessel GM, Wikramanayake AH, Cheeseman IM
Citation:
Curr Biol. 2021;[Epub] doi:10.1016/j.cub.2021.10.022
Epub:
Yes
Abstract:
The organismal body axes that are formed during embryogenesis are intimately linked to intrinsic asymmetries established at the...
Organism or Cell Type:
Patiria miniata (sea star)
Citation Extract:
Swartz SZ, Tan TH, Perillo M, Fakhri N, Wessel GM, Wikramanayake AH, Cheeseman IM. Polarized Dishevelled dissolution and reassembly drives embryonic axis specification in sea star oocytes. Curr Biol. 2021;[Epub] doi:10.1016/j.cub.2021.10.022.

Nxhl Controls Angiogenesis by Targeting VE-PTP Through Interaction With Nucleolin

Authors:
Honglin L, Yongde Z, Yanfei D, Lequn L, Zhaoan S, Yanling Y, Yong L, Xiaohan C, Pengfei F
Citation:
Front Cell Dev Biol. 2021;9:2716. doi:10.3389/fcell.2021.728821
Epub:
Not Epub
Abstract:
Precise regulation of angiogenesis is required for organ development, wound repair, and tumor progression. Here, we identified...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Honglin L, Yongde Z, Yanfei D, Lequn L, Zhaoan S, Yanling Y, Yong L, Xiaohan C, Pengfei F. Nxhl Controls Angiogenesis by Targeting VE-PTP Through Interaction With Nucleolin. Front Cell Dev Biol. 2021;9:2716. doi:10.3389/fcell.2021.728821.

Clonal gametogenesis is triggered by intrinsic stimuli in the hybrid's germ cells but is dependent on sex differentiation

Authors:
Tichopád T, Franěk R, Doležálková-Kaštánková M, Dedukh D, Marta A, Halačka K, Steinbach C, Janko K, Pšenička M
Citation:
Biol Reprod. 2022 Aug 9;107(2):446-457. doi: 10.1093/biolre/ioac074. PMID: 35416937
Epub:
Not Epub
Abstract:
Interspecific hybridization may trigger the transition from sexual reproduction to asexuality, but mechanistic reasons for such...
Delivery Method:
microinjection
Organism or Cell Type:
Cobitis taenia, Cobitis elongatoides (spined loach)
Citation Extract:
Tichopád T, Franěk R, Doležálková-Kaštánková M, Dedukh D, Marta A, Halačka K, Steinbach C, Janko K, Pšenička M. Clonal gametogenesis is triggered by intrinsic stimuli in the hybrid's germ cells but is dependent on sex differentiation. Biol Reprod. 2022 Aug 9;107(2):446-457. doi: 10.1093/biolre/ioac074. PMID: 35416937.

Amoeboid-like migration ensures correct horizontal cell layer formation in the developing vertebrate retina

Authors:
Amini R, Bhatnagar A, Schlüßler R, Möllmert S, Guck J, Norden C
Citation:
Elife. 2022 May 31;11:e76408. doi: 10.7554/eLife.76408. PMID: 35639083; PMCID: PMC9208757
Epub:
Not Epub
Abstract:
Migration of cells in the developing brain is integral for the establishment of neural circuits and function of the central...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Amini R, Bhatnagar A, Schlüßler R, Möllmert S, Guck J, Norden C. Amoeboid-like migration ensures correct horizontal cell layer formation in the developing vertebrate retina. Elife. 2022 May 31;11:e76408. doi: 10.7554/eLife.76408. PMID: 35639083; PMCID: PMC9208757.

Smad4 controls signaling robustness and morphogenesis by differentially contributing to the Nodal and BMP pathways

Authors:
Guglielmi L, Heliot C, Kumar S, Alexandrov Y, Gori I, Papaleonidopoulou F, Barrington C, East P, Economou AD, French PMW, McGinty J, Hill CS
Citation:
Nat Commun. 2021;12(1):6374. doi:10.1038/s41467-021-26486-3
Epub:
Not Epub
Abstract:
The transcriptional effector SMAD4 is a core component of the TGF-β family signaling pathways. However, its role in vertebrate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guglielmi L, Heliot C, Kumar S, Alexandrov Y, Gori I, Papaleonidopoulou F, Barrington C, East P, Economou AD, French PMW, McGinty J, Hill CS. Smad4 controls signaling robustness and morphogenesis by differentially contributing to the Nodal and BMP pathways. Nat Commun. 2021;12(1):6374. doi:10.1038/s41467-021-26486-3.

NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration

Authors:
Laplace-Builhé B, Barthelaix A, Assou S, Bohaud C, Pratlong M, Severac D, Tejedor G, Luz-Crawford P, Nguyen-Chi M, Mathieu M, Jorgensen C, Djouad F
Citation:
Nat Commun. 2021;12(1):6336. doi:10.1038/s41467-021-26422-5
Epub:
Not Epub
Abstract:
Fish species, such as zebrafish (Danio rerio), can regenerate their appendages after amputation through the formation of a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Laplace-Builhé B, Barthelaix A, Assou S, Bohaud C, Pratlong M, Severac D, Tejedor G, Luz-Crawford P, Nguyen-Chi M, Mathieu M, Jorgensen C, Djouad F. NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration. Nat Commun. 2021;12(1):6336. doi:10.1038/s41467-021-26422-5.

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