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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
Endoplasmic reticulum transmembrane protein TMTC3 contributes to O-mannosylation of E-cadherin, cellular adherence, and embryonic gastrulation
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Citation:
Mol Biol Cell. 2020 Feb 1;31(3):167-183. doi: 10.1091/mbc.E19-07-0408. Epub 2019 Dec 18. PMID: 31851597; PMCID: PMC7001481 Epub:
Not Epub Abstract:
Protein glycosylation plays essential roles in protein structure, stability, and activity such as cell adhesion. The cadherin... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Graham JB, Sunryd JC, Mathavan K, Weir E, Larsen ISB, Halim A, Clausen H, Cousin H, Alfandari D, Hebert DN. Endoplasmic reticulum transmembrane protein TMTC3 contributes to O-mannosylation of E-cadherin, cellular adherence, and embryonic gastrulation. Mol Biol Cell. 2020 Feb 1;31(3):167-183. doi: 10.1091/mbc.E19-07-0408. Epub 2019 Dec 18. PMID: 31851597; PMCID: PMC7001481. |
Removal of the Polyglutamine Repeat of Ataxin-3 by Redirecting pre-mRNA Processing
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Citation:
Int J Mol Sci. 2019;20(21):5434. doi:10.3390/ijms20215434 Epub:
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Spinocerebellar ataxia type 3 (SCA3) is a devastating neurodegenerative disease for which there is currently no cure, nor... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: SCA3 patient-derived dermal fibroblasts Citation Extract: McIntosh CS, Aung-Htut MT, Fletcher S, Wilton SD. Removal of the Polyglutamine Repeat of Ataxin-3 by Redirecting pre-mRNA Processing. Int J Mol Sci. 2019;20(21):5434. doi:10.3390/ijms20215434. |
Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation
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Citation:
Cell Rep. 2019;29:1082-98. doi:10.1016/j.celrep.2019.09.033 Epub:
Not Epub Abstract:
Chondrolectin (Chodl) is needed for motor axon extension in zebrafish and is dysregulated in mouse models of spinal muscular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Oprişoreanu A-M, Smith HL, Arya S, Webster R, Zhong Z, Wehner D, Cardozo MJ, Becker T, Talbot K, Becker CG. Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation. Cell Rep. 2019;29:1082-98. doi:10.1016/j.celrep.2019.09.033. |
Foxg specifies sensory neurons in the anterior neural plate border of the ascidian embryo
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Citation:
Nat Comm. 2019;10:4911 doi:10.1038/s41467-019-12839-6 Epub:
Not Epub Abstract:
Foxg constitutes a regulatory loop with Fgf8 and plays an important role in the development of anterior placodes and the... Delivery Method:
microinjection Organism or Cell Type:
Ciona robusta (AKA C. intestinalis; ascidian) Citation Extract: Liu B, Satou Y. Foxg specifies sensory neurons in the anterior neural plate border of the ascidian embryo. Nat Comm. 2019;10:4911 doi:10.1038/s41467-019-12839-6. |
Lef1 regulates caveolin expression and caveolin dependent endocytosis, a process necessary for Wnt5a/Ror2 signaling during Xenopus gastrulation
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Citation:
Sci Rep. 2019;9:15645 doi:10.1038/s41598-019-52218-1 Epub:
Not Epub Abstract:
The activation of distinct branches of the Wnt signaling network is essential for regulating early vertebrate development.... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Puzik K, Tonnier V, Opper I, Eckert A, Zhou L, Kratzer M-C, le Noble F, Nienhaus GU, Gradl D. Lef1 regulates caveolin expression and caveolin dependent endocytosis, a process necessary for Wnt5a/Ror2 signaling during Xenopus gastrulation. Sci Rep. 2019;9:15645 doi:10.1038/s41598-019-52218-1. |
MicroRNA-421 confers paclitaxel resistance by binding to the KEAP1 3′UTR and predicts poor survival in non-small cell lung cancer
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Citation:
Cell Death Dis. 2019;10:821. doi:10.1038/s41419-019-2031-1 Epub:
Not Epub Abstract:
MicroRNAs regulate post-transcriptional gene expression and play important roles in multiple cellular processes. In this study... Delivery Method:
intratumoral injection Organism or Cell Type:
cell culture: human NSCLC A549; mouse xenograft Citation Extract: Duan F-G, Wang M-F, Cao Y-B, Li D, Li R-Z, Fan X-X, Khan I, Lai H-L, Zhang Y-Z, Hsiao WW-L, Yao X-J, Wu Q-B, Liu L, Tang I-J, Leung EL-H. MicroRNA-421 confers paclitaxel resistance by binding to the KEAP1 3′UTR and predicts poor survival in non-small cell lung cancer. Cell Death Dis. 2019;10:821. doi:10.1038/s41419-019-2031-1. |
Generation of MuRF-GFP transgenic zebrafish models for investigating murf gene expression and protein localization in Smyd1b and Hsp90α1 knockdown embryos
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Citation:
Comp Biochem Physiol B. 2019;[Epub ahead of print] doi:10.1016/j.cbpb.2019.110368 Epub:
Yes Abstract:
Muscle-specific RING-finger proteins (MuRFs) are E3 ubiquitin ligases that play important roles in protein quality control in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li B, Li S, He Q, Du S. Generation of MuRF-GFP transgenic zebrafish models for investigating murf gene expression and protein localization in Smyd1b and Hsp90α1 knockdown embryos. Comp Biochem Physiol B. 2019;[Epub ahead of print] doi:10.1016/j.cbpb.2019.110368. |
POLR1B and neural crest cell anomalies in Treacher Collins syndrome type 4
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Citation:
Genet Med. 2019 Oct 24. doi: 10.1038/s41436-019-0669-9. [Epub ahead of print] Epub:
Yes Abstract:
PURPOSE: Treacher Collins syndrome (TCS) is a rare autosomal dominant mandibulofacial dysostosis, with a prevalence of 0.2-1/10... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sanchez E, Laplace-Builhé B, Mau-Them FT, Richard E, Goldenberg A, Toler TL, Guignard T, Gatinois V, Vincent M, Blanchet C, Boland A, Bihoreau MT, Deleuze JF, Olaso R, Nephi W, Lüdecke HJ, Verheij JBGM, Moreau-Lenoir F, Denoyelle F, Rivière JB, Laplanche JL, Willing M, Captier G, Apparailly F, Wieczorek D, Collet C, Djouad F, Geneviève D. POLR1B and neural crest cell anomalies in Treacher Collins syndrome type 4. Genet Med. 2019 Oct 24. doi: 10.1038/s41436-019-0669-9. [Epub ahead of print]. |
Interleukin-6 signaling regulates hematopoietic stem cell emergence
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Citation:
Exp Mol Med. 2019 Oct 24;51(10):124. doi: 10.1038/s12276-019-0320-5 Epub:
Not Epub Abstract:
Hematopoietic stem cells (HSCs) produce all lineages of mature blood cells for the lifetime of an organism. In vertebrates,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tie R, Li H, Cai S, Liang Z, Shan W, Wang B, Tan Y, Zheng W, Huang H. Interleukin-6 signaling regulates hematopoietic stem cell emergence. Exp Mol Med. 2019 Oct 24;51(10):124. doi: 10.1038/s12276-019-0320-5. |
Loss-of-spen disturbs cardiac conduction in zebrafish mediated by impaired connexin43 function
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Citation:
Eur Heart J, 2019;40(Supplement_1):ehz746.0023. doi:10.1093/eurheartj/ehz746.0023 Epub:
Not Epub Abstract:
Genome-wide association studies identified SPLIT ENDS (SPEN) gene as an interesting candidate in the pathogenesis of heart... Organism or Cell Type:
zebrafish Citation Extract: Rattka M, Westphal S, Pott A, Kessler M, Weinmann K, Just S, Rottbauer W. Loss-of-spen disturbs cardiac conduction in zebrafish mediated by impaired connexin43 function. Eur Heart J, 2019;40(Supplement_1):ehz746.0023. doi:10.1093/eurheartj/ehz746.0023. |