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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
There are 12321 scientific papers returned from the database with the search filters currently being used below.
Gene- and tissue-level interactions in normal gastrointestinal development and Hirschsprung disease
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Citation:
Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26697-26708. doi: 10.1073/pnas.1908756116. Epub 2019 Dec 9. PMID: 31818953; PMCID: PMC6936708 Epub:
Not Epub Abstract:
The development of the gut from endodermal tissue to an organ with multiple distinct structures and functions occurs over a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chatterjee S, Nandakumar P, Auer DR, Gabriel SB, Chakravarti A. Gene- and tissue-level interactions in normal gastrointestinal development and Hirschsprung disease. Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26697-26708. doi: 10.1073/pnas.1908756116. Epub 2019 Dec 9. PMID: 31818953; PMCID: PMC6936708. |
Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles
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Citation:
Adv Funct Mater. 2019;[Epub] doi:10.1002/adfm.201906432 Epub:
Not Epub Abstract:
Phosphorodiamidate morpholino oligomers (PMOs) are oligonucleotide analogs that can be used for therapeutic modulation of pre‐... Delivery Method:
nanoparticle Organism or Cell Type:
cell culture: HeLa pLuc/705, mdx52 skeletal myotubes Citation Extract: Kuhn J, Klein PM, Al Danaf N, Nordin JZ, Reinhard S, Loy DM, Höhn M, El Andaloussi S, Lamb DC, Wagner E, Aoki Y, Lehto T, Lächelt U. Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles. Adv Funct Mater. 2019;[Epub] doi:10.1002/adfm.201906432. |
Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals
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Citation:
Nat Comm. 2019;10(1):4269. doi:10.1038/s41467-019-12263-w Epub:
Not Epub Abstract:
Embryonic development yields many different cell types in response to just a few families of inductive signals. The property of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Gentsch GE, Spruce T, Owens NDL, Smith JC. Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals. Nat Comm. 2019;10(1):4269. doi:10.1038/s41467-019-12263-w. |
Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish
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Citation:
Oncotarget. 2020 Mar 31;11(13):1109-1130. doi: 10.18632/oncotarget.27521. PMID: 32284789; PMCID: PMC7138166 Epub:
Not Epub Abstract:
pVHL is a tumor suppressor. The lack of its function leads to various tumors, among which ccRCC (clear cell renal cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kim HR, Santhakumar K, Markham E, Baldera D, Greenald D, Bryant HE, El-Khamisy SF, van Eeden FJ. Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish. Oncotarget. 2020 Mar 31;11(13):1109-1130. doi: 10.18632/oncotarget.27521. PMID: 32284789; PMCID: PMC7138166. |
Rgma-induced Neo1 proteolysis promotes neural tube morphogenesis
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Citation:
J Neurosci. 2019 Aug 9. pii: 3262-18. doi: 10.1523/JNEUROSCI.3262-18.2019. [Epub ahead of print] Epub:
Yes Abstract:
Neuroepithelial cell (NEC) elongation is one of several key cell behaviors that mediate the tissue-level morphogenetic... Organism or Cell Type:
zebrafish Citation Extract: Brown S, Jayachandran P, Negesse M, Olmo V, Vital E, Brewster R. Rgma-induced Neo1 proteolysis promotes neural tube morphogenesis. J Neurosci. 2019 Aug 9. pii: 3262-18. doi: 10.1523/JNEUROSCI.3262-18.2019. [Epub ahead of print]. |
The evolution of a new cell type was associated with competition for a signaling ligand
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Citation:
PLoS Biol. 2019;17(9):e3000460. doi:10.1371/journal.pbio.3000460 Epub:
Not Epub Abstract:
There is presently a very limited understanding of the mechanisms that underlie the evolution of new cell types. The skeleton-... Delivery Method:
microinjection Organism or Cell Type:
Lytechinus variegatus (sea urchin) Citation Extract: Ettensohn CA, Adomako-Ankomah A. The evolution of a new cell type was associated with competition for a signaling ligand. PLoS Biol. 2019;17(9):e3000460. doi:10.1371/journal.pbio.3000460. |
BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers
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Citation:
Sci Adv. 2019;5(9):eaax1734. doi:10.1126/sciadv.aax1738 Epub:
Not Epub Abstract:
The BAP1 tumor suppressor is mutated in many human cancers such as uveal melanoma, leading to poor patient outcome. It remains... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Kuznetsov JN, Aguero TH, Owens DA, Kurtenbach S, Field MG, Durante MA. BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers. Sci Adv. 2019;5(9):eaax1734. doi:10.1126/sciadv.aax1738. |
TEADs, Yap, Taz, Vgll4s transcription factors control the establishment of Left-Right asymmetry in Zebrafish
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Citation:
Elife. 2019 Sep 12;8. pii: e45241. doi: 10.7554/eLife.45241. [Epub ahead of print] Epub:
Not Epub Abstract:
In many vertebrates, establishment of Left-Right (LR) asymmetry results from the activity of a ciliated organ functioning as... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fillatre J, Fauny JD, Fels JA, Li C, Goll M, Thisse C, Thisse B. TEADs, Yap, Taz, Vgll4s transcription factors control the establishment of Left-Right asymmetry in Zebrafish. Elife. 2019 Sep 12;8. pii: e45241. doi: 10.7554/eLife.45241. [Epub ahead of print]. |
miR-301a Regulates Inflammatory Response to Japanese Encephalitis Virus Infection via Suppression of NKRF Activity
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Citation:
J Immunol. 2019 Oct 15;203(8):2222-2238. doi: 10.4049/jimmunol.1900003. Epub 2019 Sep 16. PMID: 31527198. Epub:
Yes Abstract:
Microglia being the resident macrophage of brain provides neuroprotection following diverse microbial infections. Japanese... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Hazra B, Chakraborty S, Bhaskar M, Mukherjee S, Mahadevan A, Basu A. miR-301a Regulates Inflammatory Response to Japanese Encephalitis Virus Infection via Suppression of NKRF Activity. J Immunol. 2019 Oct 15;203(8):2222-2238. doi: 10.4049/jimmunol.1900003. Epub 2019 Sep 16. PMID: 31527198.. |
ECM alterations in Fndc3a (Fibronectin Domain Containing Protein 3A) deficient zebrafish cause temporal fin development and regeneration defects
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Citation:
Sci Rep. 2019;9(1):13383. doi:10.1038/s41598-019-50055-w Epub:
Not Epub Abstract:
Fin development and regeneration are complex biological processes that are highly relevant in teleost fish. They share genetic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liedtke D, Orth M, Meissler M, Geuer S, Knaup S, Köblitz I, Klopocki E. ECM alterations in Fndc3a (Fibronectin Domain Containing Protein 3A) deficient zebrafish cause temporal fin development and regeneration defects. Sci Rep. 2019;9(1):13383. doi:10.1038/s41598-019-50055-w. |