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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12407 scientific papers returned from the database with the search filters currently being used below.
There are 12407 scientific papers returned from the database with the search filters currently being used below.
A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling
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Citation:
Cell Rep. 2019;28(7):1907-22. doi:10.1016/j.celrep.2019.07.025 Epub:
Not Epub Abstract:
CEP104 is an evolutionarily conserved centrosomal and ciliary tip protein. CEP104 loss-of-function mutations are reported in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Frikstad K-AM, Molinari E, Thoresen M, Roepman R, Sayer JA, Patzke S. A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling. Cell Rep. 2019;28(7):1907-22. doi:10.1016/j.celrep.2019.07.025. |
Gulp1 controls Eph/ephrin trogocytosis and is important for cell rearrangements during development
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Citation:
J Cell Biol. 2019;]Epub ahead of print] doi:10.1083/jcb.201901032 Epub:
Yes Abstract:
Trogocytosis, in which cells nibble away parts of neighboring cells, is an intercellular cannibalism process conserved from... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Gong J, Gaitanos TN, Luu O, Huang Y, Gaitanos L, Lindner J, Winklbauer R, Rüdiger Klein R. Gulp1 controls Eph/ephrin trogocytosis and is important for cell rearrangements during development. J Cell Biol. 2019;]Epub ahead of print] doi:10.1083/jcb.201901032. |
In Vitro Validation of Phosphorodiamidate Morpholino Oligomers
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Citation:
Molecules. 2019;24(6):2922 doi:0.3390/molecules24162922 Epub:
Not Epub Abstract:
One of the crucial aspects of screening antisense oligonucleotides destined for therapeutic application is confidence that the... Delivery Method:
electroporation Lipofectin Lipofectamine Endo-Porter Organism or Cell Type:
cell culture: human dermal fibroblasts, human myoblasts Citation Extract: Aung-Htut MT, McIntosh CS, West KA, Fletcher S, Wilton SD. In Vitro Validation of Phosphorodiamidate Morpholino Oligomers. Molecules. 2019;24(6):2922 doi:0.3390/molecules24162922. |
De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies
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Citation:
Am J Hum Genet. 2019;[Epub ahead of print] doi:10.1016/j.ajhg.2019.07.005 Epub:
Yes Abstract:
The identification of genetic variants implicated in human developmental disorders has been revolutionized by second-generation... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Holt RJ, Young RM, Crespo B, Ceroni F, Curry CJ, Bellacchio E, Bax DA, Ciolfi A, Simon M, Fagerberg CR, van Binsbergen E, De Luca A, Memo L, Dobyns WB, Mohammed AA, Clokie SJH, Seco CZ, Jiang Y-H, Sørensen KP, Andersen H, Sullivan J, Powis Z, Chassevent A, Smith-Hicks C, Petrovski S, Antoniadi T, Shashi V, Gelb BD, Wilson SW, Gerrelli D, Tartaglia M, Chassaing N, Calvas P, Ragge NK. De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies. Am J Hum Genet. 2019;[Epub ahead of print] doi:10.1016/j.ajhg.2019.07.005. |
Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium
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Citation:
Nat Comm. 2019;10(1):3577. doi:10.1038/s41467-019-11423-2 Epub:
Not Epub Abstract:
Haematopoietic stem cells are generated from the haemogenic endothelium (HE) located in the floor of the dorsal aorta (DA).... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bonkhofer F, Rispoli R, Pinheiro P, Krecsmarik M, Schneider-Swales J, Tsang IHC, de Bruijn M, Monteiro R, Peterkin T, Patient R. Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium. Nat Comm. 2019;10(1):3577. doi:10.1038/s41467-019-11423-2. |
TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes
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Citation:
J Virol. 2019 Oct 15;93(21):e00649-19. doi: 10.1128/JVI.00649-19. PMID: 31391268; PMCID: PMC6803253 Epub:
Yes Abstract:
Cleavage of influenza virus hemagglutinin (HA) by host cell proteases is essential for virus infectivity and spread. We... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: primary human bronchial epithelial cells (HBEC), primary type II alveolar epithelial cells (AECII) and Calu-3 cells Citation Extract: Limburg H, Harbig A, Bestle D, Stein DA, Moulton HM, Jaeger J, Janga H, Hardes K, Koepke J, Schulte L, Koczulla AR, Schmeck B, Klenk HD, Böttcher-Friebertshäuser E. TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes. J Virol. 2019 Oct 15;93(21):e00649-19. doi: 10.1128/JVI.00649-19. PMID: 31391268; PMCID: PMC6803253. |
Zebrafish Dynamin is required for maintenance of enveloping layer integrity and the progression of epiboly
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Citation:
Dev Biol. 2014 Jan 1;385(1):52-66. doi: 10.1016/j.ydbio.2013.10.015. Epub 2013 Oct 24 Epub:
Not Epub Abstract:
Epiboly, the first morphogenetic cell movement that occurs in the zebrafish embryo, is the process by which the blastoderm... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lepage SE, Tada M, Bruce AE. Zebrafish Dynamin is required for maintenance of enveloping layer integrity and the progression of epiboly. Dev Biol. 2014 Jan 1;385(1):52-66. doi: 10.1016/j.ydbio.2013.10.015. Epub 2013 Oct 24. |
Planar polarization of cilia in the zebrafish floor-plate involves Par3-mediated posterior localization of highly motile basal bodies
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Citation:
Development. 2021 Jul 1;148(13):dev196386. doi: 10.1242/dev.196386. Epub 2021 Jul 8. PMID: 34104942 Epub:
Not Epub Abstract:
Epithelial cilia, whether motile or primary, often display an off-center planar localization within the apical cell surface.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Donati A, Anselme I, Schneider-Maunoury S, Vesque C. Planar polarization of cilia in the zebrafish floor-plate involves Par3-mediated posterior localization of highly motile basal bodies. Development. 2021 Jul 1;148(13):dev196386. doi: 10.1242/dev.196386. Epub 2021 Jul 8. PMID: 34104942. |
BMP signaling is enhanced intracellularly by FHL3 controlling WNT-dependent spatiotemporal emergence of the neural crest
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Citation:
Cell Rep. 2021 Jun 22;35(12):109289. doi: 10.1016/j.celrep.2021.109289. PMID: 34161771 Epub:
Not Epub Abstract:
The spatiotemporal coordination of multiple morphogens is essential for embryonic patterning yet poorly understood. During... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Alkobtawi M, Pla P, Monsoro-Burq AH. BMP signaling is enhanced intracellularly by FHL3 controlling WNT-dependent spatiotemporal emergence of the neural crest. Cell Rep. 2021 Jun 22;35(12):109289. doi: 10.1016/j.celrep.2021.109289. PMID: 34161771. |
NAD+ improves neuromuscular development in a zebrafish model of FKRP-associated dystroglycanopathy
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Citation:
Skeletal Musc. 2019;9:21. doi:10.1186/s13395-019-0206-1 Epub:
Not Epub Abstract:
Background: Secondary dystroglycanopathies are muscular dystrophies that result from mutations in genes that participate in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bailey EC, Alrowaished SS, Kilroy EA, Crooks ES, Drinkert DM, Karunasiri CM, Belanger JJ, Khalil A, Kelley JB, Henry CA. NAD+ improves neuromuscular development in a zebrafish model of FKRP-associated dystroglycanopathy. Skeletal Musc. 2019;9:21. doi:10.1186/s13395-019-0206-1. |