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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12420 scientific papers returned from the database with the search filters currently being used below.
There are 12420 scientific papers returned from the database with the search filters currently being used below.
Hypothalamic nesfatin-1 mediates feeding behavior via MC3/4R-ERK signaling pathway after weight loss in obese Sprague-Dawley rats
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Citation:
Peptides. 2019 Jun 28. pii: S0196-9781(19)30038-5. doi: 10.1016/j.peptides.2019.04.007. [Epub ahead of print] Epub:
Yes Abstract:
Nesfatin-1 is an anorexic peptide derived from nucleobindin 2 (NUCB2). An increase in hypothalamic nesfatin-1 inhibits feeding... Delivery Method:
intracerebroventricular infusion Organism or Cell Type:
rats Citation Extract: Wang Y. Hypothalamic nesfatin-1 mediates feeding behavior via MC3/4R-ERK signaling pathway after weight loss in obese Sprague-Dawley rats. Peptides. 2019 Jun 28. pii: S0196-9781(19)30038-5. doi: 10.1016/j.peptides.2019.04.007. [Epub ahead of print]. |
Glucocorticoid receptor-dependent induction of cripto-1 (one-eyed pinhead) inhibits zebrafish caudal fin regeneration
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Citation:
Toxicol Rep. 2019 May 29;6:529-537. doi: 10.1016/j.toxrep.2019.05.013. eCollection 2019 Epub:
Not Epub Abstract:
We previously used a chemical genetics approach with the larval zebrafish to identify small molecule inhibitors of tissue... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Garland MA, Sengupta S, Mathew LK, Truong L, de Jong E, Piersma AH, La Du J, Tanguay RL. Glucocorticoid receptor-dependent induction of cripto-1 (one-eyed pinhead) inhibits zebrafish caudal fin regeneration. Toxicol Rep. 2019 May 29;6:529-537. doi: 10.1016/j.toxrep.2019.05.013. eCollection 2019. |
Dual roles of hydrogen peroxide in promoting zebrafish renal repair and regeneration
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Citation:
Biochem Biophys Res Commun. 2019 Jun 24. pii: S0006-291X(19)31178-7. doi: 10.1016/j.bbrc.2019.06.052. [Epub ahead of print] Epub:
Yes Abstract:
Acute renal injury (AKI) is a serious disorder of renal failure or renal damage that occurs within hours or days. At present,... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Chen J, Yu T, He X, Fu Y, Dai L, Wang B, Wu Y, He J, Li Y, Zhang F, Zhao J, Liu C. Dual roles of hydrogen peroxide in promoting zebrafish renal repair and regeneration. Biochem Biophys Res Commun. 2019 Jun 24. pii: S0006-291X(19)31178-7. doi: 10.1016/j.bbrc.2019.06.052. [Epub ahead of print]. |
The combination of loss of glyoxalase1 and obesity results in hyperglycemia
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Citation:
JCI Insight. 2019 Jun 20;4(12). pii: 126154. doi: 10.1172/jci.insight.126154. eCollection 2019 Jun 20 Epub:
Not Epub Abstract:
The increased formation of methylglyoxal (MG) under hyperglycemia is associated with the development of microvascular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lodd E, Wiggenhauser LM, Morgenstern J, Fleming TH, Poschet G, Büttner M, Tabler CT, Wohlfart DP, Nawroth PP, Kroll J. The combination of loss of glyoxalase1 and obesity results in hyperglycemia. JCI Insight. 2019 Jun 20;4(12). pii: 126154. doi: 10.1172/jci.insight.126154. eCollection 2019 Jun 20. |
Direct Reprogramming of Human DMD Fibroblasts into Myotubes for In Vitro Evaluation of Antisense-Mediated Exon Skipping and Exons 45-55 Skipping Accompanied by Rescue of Dystrophin Expression
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Citation:
Methods Mol Biol. 2018;1828:141-150. doi: 10.1007/978-1-4939-8651-4_8 Epub:
Not Epub Abstract:
Antisense oligonucleotide-mediated exon skipping is a promising therapeutic approach for the treatment of various genetic... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: primary human fibroblasts (DMD) Citation Extract: Lee JJA, Saito T, Duddy W, Takeda S, Yokota T. Direct Reprogramming of Human DMD Fibroblasts into Myotubes for In Vitro Evaluation of Antisense-Mediated Exon Skipping and Exons 45-55 Skipping Accompanied by Rescue of Dystrophin Expression. Methods Mol Biol. 2018;1828:141-150. doi: 10.1007/978-1-4939-8651-4_8. |
Stop-gain mutations in UBAP1 cause pure autosomal-dominant spastic paraplegia
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Citation:
Brain. 2019 Jun 15. pii: awz158. doi: 10.1093/brain/awz158. [Epub ahead of print] Epub:
Not Epub Abstract:
Hereditary spastic paraplegias refer to a heterogeneous group of neurodegenerative disorders resulting from degeneration of the... Organism or Cell Type:
zebrafish Citation Extract: Lin X, Su HZ, Dong EL, Lin XH, Zhao M, Yang C, Wang C, Wang J, Chen YJ, Yu H, Xu J, Ma LX, Xiong ZQ, Wang N, Chen WJ. Stop-gain mutations in UBAP1 cause pure autosomal-dominant spastic paraplegia. Brain. 2019 Jun 15. pii: awz158. doi: 10.1093/brain/awz158. [Epub ahead of print]. |
Zebrafish macroH2A variants have distinct embryo localization and function
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Citation:
Sci Rep. 2019 Jun 14;9(1):8632. doi: 10.1038/s41598-019-45058-6 Epub:
Not Epub Abstract:
Mouse and cell-based studies have shown that macroH2A histone variants predominantly associate with heterochromatin. Functional... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gonzalez-Munoz E, Arboleda-Estudillo Y, Chanumolu SK, Otu HH, Cibelli JB. Zebrafish macroH2A variants have distinct embryo localization and function. Sci Rep. 2019 Jun 14;9(1):8632. doi: 10.1038/s41598-019-45058-6. |
β6 integrinosis: a new lethal autosomal recessive ITGB6 disorder leading to impaired conformational transitions of the αVβ6 integrin receptor
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Citation:
Gut. 2019;[Epub ahead of print] doi:10.1136/gutjnl-2019-319015 Epub:
Yes Abstract:
[no abstract available] Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Weil P, van den Bruck R, Ziegenhals T, Juranek S, Goedde D, Orth V, Wirth S, Jenke AC, Postberg J. β6 integrinosis: a new lethal autosomal recessive ITGB6 disorder leading to impaired conformational transitions of the αVβ6 integrin receptor. Gut. 2019;[Epub ahead of print] doi:10.1136/gutjnl-2019-319015 . |
The Spatiotemporal Control of Zygotic Genome Activation
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Citation:
iScience. 2019 Jun 11;16:485-498. doi: 10.1016/j.isci.2019.06.013. [Epub ahead of print] Epub:
Not Epub Abstract:
One of the earliest and most significant events in embryonic development is zygotic genome activation (ZGA). In several species... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Gentsch GE, Owens NDL, Smith JC. The Spatiotemporal Control of Zygotic Genome Activation. iScience. 2019 Jun 11;16:485-498. doi: 10.1016/j.isci.2019.06.013. [Epub ahead of print]. |
The nuclear pore proteins Nup88/214 and T-ALL-associated NUP214 fusion proteins regulate Notch signaling
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Citation:
J Biol Chem. 2019 Jun 11. pii: jbc.RA118.006357. doi: 10.1074/jbc.RA118.006357. [Epub ahead of print] Epub:
Yes Abstract:
The Notch receptor is a key mediator of developmental programs and cell-fate decisions. Imbalanced Notch signaling leads to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kindermann B, Valkova C, Krämer A, Perner B, Engelmann C, Behrendt L, Kritsch D, Jungnickel B, Kehlenbach RH, Oswald F, Englert C, Kaether C. The nuclear pore proteins Nup88/214 and T-ALL-associated NUP214 fusion proteins regulate Notch signaling. J Biol Chem. 2019 Jun 11. pii: jbc.RA118.006357. doi: 10.1074/jbc.RA118.006357. [Epub ahead of print]. |