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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12221 scientific papers returned from the database with the search filters currently being used below.

Diflovidazin damages the hematopoietic stem cells to zebrafish embryos via the TLR4/ NF-κB/ p53 pathway

Authors:
Jia K, Xiong H, Yuan W, Huang L, Xu J, Lu C, Hu Y, Huang K, Luo Q, Ma J, Lu H
Citation:
Fish Shellfish Immunol. 2023 Mar 7:108672. doi: 10.1016/j.fsi.2023.108672. Online ahead of print
Epub:
Yes
Abstract:
Exposure to environmental contaminants frequently induces the occurrence of blood diseases, but the underlying molecular...
Organism or Cell Type:
zebrafish
Citation Extract:
Jia K, Xiong H, Yuan W, Huang L, Xu J, Lu C, Hu Y, Huang K, Luo Q, Ma J, Lu H. Diflovidazin damages the hematopoietic stem cells to zebrafish embryos via the TLR4/ NF-κB/ p53 pathway. Fish Shellfish Immunol. 2023 Mar 7:108672. doi: 10.1016/j.fsi.2023.108672. Online ahead of print.

Analysis of incidental findings in Qatar genome participants reveals novel functional variants in LMNA and DSP

Authors:
Elfatih A, Da'as SI, Abdelrahman D, Mbarek H, Mohammed I, Hasan W, Fakhro KA; The Qatar Genome Program Research Consortium; Estivill X, Mifsud B
Citation:
Hum Mol Genet. 2022 Aug 23;31(16):2796-2809. doi: 10.1093/hmg/ddac073
Epub:
Not Epub
Abstract:
In order to report clinically actionable incidental findings in genetic testing, the American College of Medical Genetics and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Elfatih A, Da'as SI, Abdelrahman D, Mbarek H, Mohammed I, Hasan W, Fakhro KA; The Qatar Genome Program Research Consortium; Estivill X, Mifsud B. Analysis of incidental findings in Qatar genome participants reveals novel functional variants in LMNA and DSP. Hum Mol Genet. 2022 Aug 23;31(16):2796-2809. doi: 10.1093/hmg/ddac073.

Gold nanoparticles conjugated DNA-tile nanomaterials for simultaneous delivery of morpholino antisense oligonucleotides and doxorubicin

Authors:
Tunc CU, Culha M
Citation:
J Drug Deliv Sci Technol. 2022;74:103546. doi:10.1016/j.jddst.2022.103546
Epub:
Not Epub
Abstract:
Current therapies have limited treatment effect on cancer. Combinational delivery of multiple therapeutics has been commonly...
Delivery Method:
nanoparticle
Organism or Cell Type:
cell culture: breast cancer
Citation Extract:
Tunc CU, Culha M. Gold nanoparticles conjugated DNA-tile nanomaterials for simultaneous delivery of morpholino antisense oligonucleotides and doxorubicin. J Drug Deliv Sci Technol. 2022;74:103546. doi:10.1016/j.jddst.2022.103546.

Nucleolar URB1 ensures 3′ ETS rRNA removal to prevent exosome surveillance

Authors:
Shan L, Xu G, Yao R-W, Luan P-F, Huang Y, Zhang P-H, Pan Y-H, Zhang L, Gao X, Li Y, Cao S-M, Gao S-X, Yang Z-H, Li S, Yang L-Z, Wang Y, Wong CCL, Yu L, Li J, Yang L, Chen L-L
Citation:
Nature. 2023;[Epub ahead of orint]. doi:10.1038/s41586-023-05767-5
Epub:
Not Epub
Abstract:
The nucleolus is the most prominent membraneless condensate in the nucleus. It comprises hundreds of proteins with distinct...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shan L, Xu G, Yao R-W, Luan P-F, Huang Y, Zhang P-H, Pan Y-H, Zhang L, Gao X, Li Y, Cao S-M, Gao S-X, Yang Z-H, Li S, Yang L-Z, Wang Y, Wong CCL, Yu L, Li J, Yang L, Chen L-L. Nucleolar URB1 ensures 3′ ETS rRNA removal to prevent exosome surveillance. Nature. 2023;[Epub ahead of orint]. doi:10.1038/s41586-023-05767-5.

Mucociliary Wnt signaling promotes cilia biogenesis and beating

Authors:
Seidl C, Da Silva F, Zhang K, Wohlgemuth K, Omran H, Niehrs C
Citation:
Nat Commun. 2023 Mar 6;14(1):1259. doi: 10.1038/s41467-023-36743-2
Epub:
Not Epub
Abstract:
It is widely thought that Wnt/Lrp6 signaling proceeds through the cytoplasm and that motile cilia are signaling-inert...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Seidl C, Da Silva F, Zhang K, Wohlgemuth K, Omran H, Niehrs C. Mucociliary Wnt signaling promotes cilia biogenesis and beating. Nat Commun. 2023 Mar 6;14(1):1259. doi: 10.1038/s41467-023-36743-2.

Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis

Authors:
Murayama E, Vivier C, Schmidt A, Herbomel P
Citation:
Nat Commun. 2023 Mar 1;14(1):1171. doi: 10.1038/s41467-023-36612-y
Epub:
Not Epub
Abstract:
Mesenchymal stromal cells are essential components of hematopoietic stem and progenitor cell (HSPC) niches, regulating HSPC...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Murayama E, Vivier C, Schmidt A, Herbomel P. Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis. Nat Commun. 2023 Mar 1;14(1):1171. doi: 10.1038/s41467-023-36612-y.

sox1a:eGFP transgenic line and single-cell transcriptomics reveal the origin of zebrafish intraspinal serotonergic neurons

Authors:
Chen F, Köhler M, Cucun G, Takamiya M, Kizil C, Cosacak MI, Rastegar S
Citation:
iScience. 2023 Jul 11;26(8):107342. doi: 10.1016/j.isci.2023.107342. PMID: 37529101; PMCID: PMC10387610
Epub:
Not Epub
Abstract:
Sox transcription factors are crucial for vertebrate nervous system development. In zebrafish embryo, sox1 genes are expressed...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen F, Köhler M, Cucun G, Takamiya M, Kizil C, Cosacak MI, Rastegar S. sox1a:eGFP transgenic line and single-cell transcriptomics reveal the origin of zebrafish intraspinal serotonergic neurons. iScience. 2023 Jul 11;26(8):107342. doi: 10.1016/j.isci.2023.107342. PMID: 37529101; PMCID: PMC10387610.

Functional Differentiation of Cyclins and Cyclin-Dependent Kinases in Giardia lamblia

Authors:
Kim J, Park EA, Shin MY, Park SJ
Citation:
Microbiol Spectr. 2023 Mar 6:e0491922. doi: 10.1128/spectrum.04919-22. Online ahead of print
Epub:
Not Epub
Abstract:
Cyclin-dependent kinases (CDKs) are serine/threonine kinases that control the eukaryotic cell cycle. Limited information is...
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Kim J, Park EA, Shin MY, Park SJ. Functional Differentiation of Cyclins and Cyclin-Dependent Kinases in Giardia lamblia. Microbiol Spectr. 2023 Mar 6:e0491922. doi: 10.1128/spectrum.04919-22. Online ahead of print.

YULINK regulates vascular formation in zebrafish and HUVECs

Authors:
Lin HH, Kuo MW, Fan TC, Yu AL, Yu J
Citation:
Biol Res. 2023;56(7). doi:10.1186/s40659-023-00415-8
Epub:
Not Epub
Abstract:
Background: The distinct arterial and venous cell fates are dictated by a combination of various genetic factors which form...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin HH, Kuo MW, Fan TC, Yu AL, Yu J. YULINK regulates vascular formation in zebrafish and HUVECs. Biol Res. 2023;56(7). doi:10.1186/s40659-023-00415-8.

In-Cell Penetration Selection-Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery

Authors:
Schissel CK, Farquhar CE, Loas A, Malmberg AB, Pentelute BL
Citation:
ACS Chem Biol. 2023 Mar 1. doi: 10.1021/acschembio.2c00920. Online ahead of print
Epub:
Yes
Abstract:
Peptide-mediated delivery of macromolecules in cells has significant potential therapeutic benefits, but no therapy employing...
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Schissel CK, Farquhar CE, Loas A, Malmberg AB, Pentelute BL. In-Cell Penetration Selection-Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery. ACS Chem Biol. 2023 Mar 1. doi: 10.1021/acschembio.2c00920. Online ahead of print.

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