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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

'Shaping' of cell signaling via AKAP-tethered PDE4D: Probing with AKAR2-AKAP5 biosensor

Authors:
Koçer SS, Wang HY, Malbon CC
Citation:
J Mol Signaling. 2012;7:4 doi:10.1186/1750-2187-7-4
Epub:
Not Epub
Abstract:
Background PKA, a key regulator of cell signaling, phosphorylates a diverse and important array of target molecules and is...
Organism or Cell Type:
cell culture: HEK 293
Citation Extract:
Koçer SS, Wang HY, Malbon CC. 'Shaping' of cell signaling via AKAP-tethered PDE4D: Probing with AKAR2-AKAP5 biosensor. J Mol Signaling. 2012;7:4 doi:10.1186/1750-2187-7-4.

A functional analysis of GABARAP on 17p13.1 by knockdown zebrafish

Authors:
Komoike Y, Shimojima K, Liang JS, Fujii H, Maegaki Y, Osawa M, Fujii S, Higashinakagawa T, Yamamoto T
Citation:
J Hum Genet. 2010 Jan 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Array-based comparative genomic hybridization identified a 2.3-Mb microdeletion of 17p13.2p13.1 in a boy presenting with...
Organism or Cell Type:
zebrafish
Citation Extract:
Komoike Y, Shimojima K, Liang JS, Fujii H, Maegaki Y, Osawa M, Fujii S, Higashinakagawa T, Yamamoto T. A functional analysis of GABARAP on 17p13.1 by knockdown zebrafish. J Hum Genet. 2010 Jan 29. [Epub ahead of print].

A PATO-compliant zebrafish screening database (MODB): management of morpholino knockdown screen information

Authors:
Knowlton MN, Li T, Ren Y, Bill BR, Ellis LB, Ekker SC
Citation:
BMC Bioinformatics. 2008 Jan 7;9(1):7 [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: The zebrafish is a powerful model vertebrate amenable to high throughput in vivo genetic analyses. For...
Citation Extract:
Knowlton MN, Li T, Ren Y, Bill BR, Ellis LB, Ekker SC. A PATO-compliant zebrafish screening database (MODB): management of morpholino knockdown screen information. BMC Bioinformatics. 2008 Jan 7;9(1):7 [Epub ahead of print].

A search for factors specifying tonotopy implicates DNER in hair-cell development in the chick's cochlea

Authors:
Kowalik L, Hudspeth AJ
Citation:
Dev Biol. 2011 Apr 8. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The accurate perception of sound frequency by vertebrates relies upon the tuning of hair cells, which are arranged along...
Delivery Method:
Vivo-Morpholino, local injection
Organism or Cell Type:
chick (Gallus gallus)
Citation Extract:
Kowalik L, Hudspeth AJ. A search for factors specifying tonotopy implicates DNER in hair-cell development in the chick's cochlea. Dev Biol. 2011 Apr 8. [Epub ahead of print].

A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor

Authors:
Knaut H, Werz C, Geisler R, Nusslein-Volhard C; Tubingen 2000 Screen Consortium
Citation:
Nature 2003 Jan 16;421(6920):279-82
Epub:
Not Epub
Abstract:
Germ cells preserve an individual's genetic information and transmit it to the next generation. Early in development germ...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Knaut H, Werz C, Geisler R, Nusslein-Volhard C; Tubingen 2000 Screen Consortium. A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor. Nature 2003 Jan 16;421(6920):279-82.

A zebrafish nanos-related gene is essential for the development of primordial germ cells

Authors:
Koprunner M, Thisse C, Thisse B, Raz E
Citation:
Genes Dev. 2001 Nov 1;15(21):2877-85
Epub:
Not Epub
Abstract:
Asymmetrically distributed cytoplasmic determinants collectively termed germ plasm have been shown to play an essential role in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Koprunner M, Thisse C, Thisse B, Raz E. A zebrafish nanos-related gene is essential for the development of primordial germ cells. Genes Dev. 2001 Nov 1;15(21):2877-85.

Active repression of RAR signaling is required for head formation

Authors:
Koide T, Downes M, Chandraratna RA, Blumberg B, Umesono K
Citation:
Genes Dev 2001 Aug 15;15(16):2111-21
Epub:
Not Epub
Abstract:
The retinoic acid receptors (RARs) recruit coactivator and corepressor proteins to activate or repress the transcription of...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Koide T, Downes M, Chandraratna RA, Blumberg B, Umesono K. Active repression of RAR signaling is required for head formation. Genes Dev 2001 Aug 15;15(16):2111-21.

ANDROGEN RECEPTOR DOWN-REGULATION IN PROSTATE CANCER WITH PHOSPHORODIAMIDATE MORPHOLINO ANTISENSE OLIGOMERS

Authors:
Ko YJ, Devi GR, London CA, Kayas A, Reddy MT, Iversen PL, Bubley GJ, Balk SP
Citation:
J Urol. 2004 Sep;172(3):1140-1144
Epub:
Not Epub
Abstract:
PURPOSE:: Androgen receptor (AR) has a pivotal role in the growth and proliferation of prostate cancer (PCa). Even in advanced...
Delivery Method:
culture: scrape loading and syringe loading; mouse: IP injection
Organism or Cell Type:
in vitro: cell cultrure: HeLa-Pluc Cell; in vivo: NCr nude mice with LAPC-4 prostate cancer cells
Citation Extract:
Ko YJ, Devi GR, London CA, Kayas A, Reddy MT, Iversen PL, Bubley GJ, Balk SP. ANDROGEN RECEPTOR DOWN-REGULATION IN PROSTATE CANCER WITH PHOSPHORODIAMIDATE MORPHOLINO ANTISENSE OLIGOMERS. J Urol. 2004 Sep;172(3):1140-1144.

Antisense oligonucleotide therapeutics for iron-sulphur cluster deficiency myopathy

Authors:
Kollberg G, Holme E
Citation:
Neuromuscul Disord. 2009 Dec;19(12):833-6. doi: 10.1016/j.nmd.2009.09.011
Epub:
Not Epub
Abstract:
Iron-sulphur cluster deficiency myopathy is caused by a deep intronic mutation in ISCU resulting in inclusion of a cryptic exon...
Link:
https://www.nmd-journal.com/article/S0960-8966(09)00651-8/fulltext
Organism or Cell Type:
cell culture: primary human fibroblasts
Citation Extract:
Kollberg G, Holme E. Antisense oligonucleotide therapeutics for iron-sulphur cluster deficiency myopathy. Neuromuscul Disord. 2009 Dec;19(12):833-6. doi: 10.1016/j.nmd.2009.09.011.

AP2-dependent signals from the ectoderm regulate craniofacial development in the zebrafish embryo

Authors:
Knight RD, Javidan Y, Zhang T, Nelson S, Schilling TF
Citation:
Development. 2005 Jul;132(13):3127-38
Epub:
Not Epub
Abstract:
AP2 transcription factors regulate many aspects of embryonic development. Studies of AP2a (Tfap2a) function in mice and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Knight RD, Javidan Y, Zhang T, Nelson S, Schilling TF. AP2-dependent signals from the ectoderm regulate craniofacial development in the zebrafish embryo. Development. 2005 Jul;132(13):3127-38.

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