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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12179 scientific papers returned from the database with the search filters currently being used below.

The role of cldnh during the early retinal development in zebrafish

Authors:
Lu J, Liu R, Miao A, Chen X, Xiao W, Wang Y, Cao D, Pan J, Li L, Luo Y
Citation:
Exp Eye Res. 2020 Aug 28:108207. doi: 10.1016/j.exer.2020.108207. Online ahead of print
Epub:
Yes
Abstract:
Claudin-3, an integral component of tight junction, has recently been shown to be expressed in retinal ganglion cells, retinal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu J, Liu R, Miao A, Chen X, Xiao W, Wang Y, Cao D, Pan J, Li L, Luo Y. The role of cldnh during the early retinal development in zebrafish. Exp Eye Res. 2020 Aug 28:108207. doi: 10.1016/j.exer.2020.108207. Online ahead of print.

Calcium-Mediated In Vitro Transfection Technique of Oligonucleotides with Broad Chemical Modification Compatibility

Authors:
Wada F, Hori SI, Obika S, Yamamoto T
Citation:
Methods Mol Biol. 2020;2176:141-154. doi: 10.1007/978-1-0716-0771-8_10
Epub:
Not Epub
Abstract:
Oligonucleotide drugs (ODs) have gained increasing attention owing to their promising therapeutic potential. One major obstacle...
Delivery Method:
calcium enrichment method (CEM)
Organism or Cell Type:
cell culture
Citation Extract:
Wada F, Hori SI, Obika S, Yamamoto T. Calcium-Mediated In Vitro Transfection Technique of Oligonucleotides with Broad Chemical Modification Compatibility. Methods Mol Biol. 2020;2176:141-154. doi: 10.1007/978-1-0716-0771-8_10.

Inhibition of GABAA-ρ receptors induces retina regeneration in zebrafish

Authors:
Kent MR, Kara N, Patton JG
Citation:
Neural Regen Res. 2021 Feb;16(2):367-374. doi: 10.4103/1673-5374.286972
Epub:
Not Epub
Abstract:
A potential treatment for retinal diseases is to induce an endogenous Müller glia (MG)-derived regenerative response to replace...
Organism or Cell Type:
zebrafish
Citation Extract:
Kent MR, Kara N, Patton JG. Inhibition of GABAA-ρ receptors induces retina regeneration in zebrafish. Neural Regen Res. 2021 Feb;16(2):367-374. doi: 10.4103/1673-5374.286972.

Physiology and morphological correlates of excitatory transmission are preserved in glutamine transporter SN1- depleted mouse frontal cortex

Authors:
Popek M, Bobula B, Sowa J, Hess G, Frontczak-Baniewicz M, Albrecht J, Zielińska M
Citation:
Neurosci. 2020;[Epub] doi:10.1016/j.neuroscience.2020.08.019
Epub:
Not Epub
Abstract:
Glutamine is an astroglia-derived precursor of the neurotransmitter glutamate, and its astroglia-to-neuron transfer is...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Popek M, Bobula B, Sowa J, Hess G, Frontczak-Baniewicz M, Albrecht J, Zielińska M. Physiology and morphological correlates of excitatory transmission are preserved in glutamine transporter SN1- depleted mouse frontal cortex. Neurosci. 2020;[Epub] doi:10.1016/j.neuroscience.2020.08.019.

Llgl1 regulates zebrafish cardiac development by mediating Yap stability in cardiomyocytes

Authors:
Flinn MA, Otten C, Brandt ZJ, Bostrom JR, Kenarsary A, Wan TC, Auchampach JA, Abdelilah-Seyfried S, O'Meara CC, Link BA
Citation:
Development. 2020 Aug 25;147(16):dev193581. doi: 10.1242/dev.193581
Epub:
Not Epub
Abstract:
The Hippo-Yap pathway regulates multiple cellular processes in response to mechanical and other stimuli. In Drosophila, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Flinn MA, Otten C, Brandt ZJ, Bostrom JR, Kenarsary A, Wan TC, Auchampach JA, Abdelilah-Seyfried S, O'Meara CC, Link BA. Llgl1 regulates zebrafish cardiac development by mediating Yap stability in cardiomyocytes. Development. 2020 Aug 25;147(16):dev193581. doi: 10.1242/dev.193581.

BVES downregulation in non-syndromic tetralogy of fallot is associated with ventricular outflow tract stenosis

Authors:
Shi Y, Li Y, Wang Y, Zhu P, Chen Y, Wang H, Yue S, Xia X, Chen J, Jiang Z, Zhou C, Cai W, Yuan H, Wu Y, Wan Y, Li X, Zhu X, Zhou Z, Dai G, Li F, Mo X, Ye X, Fan X, Zhuang J, Wu X, Yuan W
Citation:
Sci Rep. 2020:(10)1:14167. doi:10.1038/s41598-020-70806-4
Epub:
Not Epub
Abstract:
BVES is a transmembrane protein, our previous work demonstrated that single nucleotide mutations of BVES in tetralogy of fallot...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shi Y, Li Y, Wang Y, Zhu P, Chen Y, Wang H, Yue S, Xia X, Chen J, Jiang Z, Zhou C, Cai W, Yuan H, Wu Y, Wan Y, Li X, Zhu X, Zhou Z, Dai G, Li F, Mo X, Ye X, Fan X, Zhuang J, Wu X, Yuan W. BVES downregulation in non-syndromic tetralogy of fallot is associated with ventricular outflow tract stenosis. Sci Rep. 2020:(10)1:14167. doi:10.1038/s41598-020-70806-4.

Selective dephosphorylation by PP2A-B55 directs the meiosis I-meiosis II transition in oocytes

Authors:
Swartz SZ, Nguyen HT, McEwan BC, Adamo ME, Cheeseman IM, Kettenbach AN
Citation:
Elife. 2021 Aug 3;10:e70588. doi: 10.7554/eLife.70588. PMID: 34342579; PMCID: PMC8370769
Epub:
Not Epub
Abstract:
Meiosis is a specialized cell cycle that requires sequential changes to the cell division machinery to facilitate changing...
Delivery Method:
microinjection
Organism or Cell Type:
Patiria miniata (sea star)
Citation Extract:
Swartz SZ, Nguyen HT, McEwan BC, Adamo ME, Cheeseman IM, Kettenbach AN. Selective dephosphorylation by PP2A-B55 directs the meiosis I-meiosis II transition in oocytes. Elife. 2021 Aug 3;10:e70588. doi: 10.7554/eLife.70588. PMID: 34342579; PMCID: PMC8370769.

The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish

Authors:
Veloso A, Bleuart A, Conrard L, Orban T, Bruyr J, Cabochette P, Germano RFV, Schevenels G, Bernard A, Zindy E, Demeyer S, Vanhollebeke B, Dequiedt F, Martin M
Citation:
BMC Biol. 2024 Feb 27;22(1):51. doi: 10.1186/s12915-024-01850-z. PMID: 38414014; PMCID: PMC10900589
Epub:
Not Epub
Abstract:
Background: Lymphangiogenesis, the formation of lymphatic vessels, is tightly linked to the development of the venous...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Veloso A, Bleuart A, Conrard L, Orban T, Bruyr J, Cabochette P, Germano RFV, Schevenels G, Bernard A, Zindy E, Demeyer S, Vanhollebeke B, Dequiedt F, Martin M. The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish. BMC Biol. 2024 Feb 27;22(1):51. doi: 10.1186/s12915-024-01850-z. PMID: 38414014; PMCID: PMC10900589.

Exploration and optimization of processes for key intermediates of phosphorodiamidate morpholino oligonucleotides.

Authors:
Chen RX, Guo JY, Song BY, Zhang ND, Xu KL, Wang GB, Dou YY, Wang QH
Citation:
Military Medical Sciences. 2017;41(8):662-666 (Chinese)
Epub:
Not Epub
Abstract:
Objective: To explore and optimize the processes for synthesis of key intermediates of phosphorodiamidate morpholino...
Citation Extract:
Chen RX, Guo JY, Song BY, Zhang ND, Xu KL, Wang GB, Dou YY, Wang QH. Exploration and optimization of processes for key intermediates of phosphorodiamidate morpholino oligonucleotides.. Military Medical Sciences. 2017;41(8):662-666 (Chinese).

Skipping Exon-v6 from CD44v6-Containing Isoforms Influences Chemotherapy Response and Self-Renewal Capacity of Gastric Cancer Cells

Authors:
Lobo S, Pereira C, Oliveira C, Almeida GM
Citation:
Cancers. 2020;12(9):2072-6694 doi:10.3390/cancers12092378
Epub:
Not Epub
Abstract:
De novo expressed CD44 isoforms containing exon-v6 are frequently associated with gastric cancer (GC) aggressiveness, and may...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human gastric cancer, MKN45 & GP202
Citation Extract:
Lobo S, Pereira C, Oliveira C, Almeida GM. Skipping Exon-v6 from CD44v6-Containing Isoforms Influences Chemotherapy Response and Self-Renewal Capacity of Gastric Cancer Cells. Cancers. 2020;12(9):2072-6694 doi:10.3390/cancers12092378.

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