You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12437 scientific papers returned from the database with the search filters currently being used below.
There are 12437 scientific papers returned from the database with the search filters currently being used below.
Sall4 regulates downstream patterning genes during limb regeneration
Citation:
Dev Biol. 2024 Jul 25:S0012-1606(24)00195-7. doi: 10.1016/j.ydbio.2024.07.015. Epub ahead of print. PMID: 39067503. Epub:
Not Epub Abstract:
Many salamanders can completely regenerate a fully functional limb. Limb regeneration is a carefully coordinated process... Delivery Method:
injection then electroporation Organism or Cell Type:
Ambystoma mexicanum (Axolotl) Citation Extract: Erickson JR, Walker SE, Arenas Gomez C, Echeverri K. Sall4 regulates downstream patterning genes during limb regeneration. Dev Biol. 2024 Jul 25:S0012-1606(24)00195-7. doi: 10.1016/j.ydbio.2024.07.015. Epub ahead of print. PMID: 39067503.. |
Crucial role for sensory nerves and Na/H exchanger inhibition in dapagliflozin- and empagliflozin-induced arterial relaxation
Citation:
Cardiovasc Res. 2024 Nov 25;120(14):1811-1824. doi: 10.1093/cvr/cvae156. PMID: 39056245; PMCID: PMC11587556 Epub:
Not Epub Abstract:
Aims: Sodium/glucose transporter 2 (SGLT2 or SLC5A2) inhibitors lower blood glucose and are also approved treatments for heart... Delivery Method:
Lipofectamine 2000 Organism or Cell Type:
NHE1 knockout mouse explant: mesenteric arteries Citation Extract: Forrester EA, Benítez-Angeles M, Redford KE, Rosenbaum T, Abbott GW, Barrese V, Dora K, Albert AP, Dannesboe J, Salles-Crawley I, Jepps TA, Greenwood IA
. Crucial role for sensory nerves and Na/H exchanger inhibition in dapagliflozin- and empagliflozin-induced arterial relaxation. Cardiovasc Res. 2024 Nov 25;120(14):1811-1824. doi: 10.1093/cvr/cvae156. PMID: 39056245; PMCID: PMC11587556. |
CPT2 Deficiency Modeled in Zebrafish: Abnormal Neural Development, Electrical Activity, Behavior, and Schizophrenia-Related Gene Expression
Citation:
Biomolecules. 2024; 14(8):914 Epub:
Not Epub Abstract:
Carnitine palmitoyltransferase 2 (CPT2) is an inner mitochondrial membrane protein of the carnitine shuttle and is involved in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Baker CE, Marta AG, Zimmerman ND, Korade Z, Mathy NW, Wilton D, Simeone T, Kochvar A, Kramer KL, Stessman HAF, Shibata A. CPT2 Deficiency Modeled in Zebrafish: Abnormal Neural Development, Electrical Activity, Behavior, and Schizophrenia-Related Gene Expression. Biomolecules. 2024; 14(8):914. |
Mycb and Mych stimulate Müller glial cell reprogramming and proliferation in the uninjured and injured zebrafish retina
Citation:
Development. 2024 Jul 10:dev.203062. doi: 10.1242/dev.203062. Epub ahead of print. PMID: 38984586 Epub:
Not Epub Abstract:
In the injured zebrafish retina, Müller glial cells (MG) reprogram to adopt retinal stem cell properties and regenerate damaged... Delivery Method:
intravitreal injection and electroporation Organism or Cell Type:
zebrafish Citation Extract: Lee MS, Jui J, Sahu A, Goldman D. Mycb and Mych stimulate Müller glial cell reprogramming and proliferation in the uninjured and injured zebrafish retina. Development. 2024 Jul 10:dev.203062. doi: 10.1242/dev.203062. Epub ahead of print. PMID: 38984586. |
Contraction-induced endocardial id2b plays a dual role in regulating myocardial contractility and valve formation
Citation:
Elife. 2025 Jul 24;13:RP101151. doi: 10.7554/eLife.101151. PMID: 40704996; PMCID: PMC12289310 Epub:
Not Epub Abstract:
Biomechanical cues play an essential role in sculpting organ formation. Comprehending how cardiac cells perceive and respond to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen S, Liang J, Yin J, Zhang W, Jiang P, Wang W, Chen X, Zhou Y, Xia P, Yang F, Gu Y, Zhang R, Han P. Contraction-induced endocardial id2b plays a dual role in regulating myocardial contractility and valve formation. Elife. 2025 Jul 24;13:RP101151. doi: 10.7554/eLife.101151. PMID: 40704996; PMCID: PMC12289310. |
Mechanical forces remodel the cardiac extracellular matrix during zebrafish development
Citation:
Development. 2024 Jul 1;151(13):dev202310. doi: 10.1242/dev.202310. Epub 2024 Jul 10. PMID: 38984541 Epub:
Not Epub Abstract:
The cardiac extracellular matrix (cECM) is fundamental for organ morphogenesis and maturation, during which time it undergoes... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gentile A, Albu M, Xu Y, Mortazavi N, Ribeiro da Silva A, Stainier DYR, Gunawan F. Mechanical forces remodel the cardiac extracellular matrix during zebrafish development. Development. 2024 Jul 1;151(13):dev202310. doi: 10.1242/dev.202310. Epub 2024 Jul 10. PMID: 38984541. |
Elp1 function in placode-derived neurons is critical for proper trigeminal ganglion development
Citation:
Dev Dyn. 2024 Oct 9. doi: 10.1002/dvdy.749. Epub ahead of print. PMID: 39381860 Epub:
Not Epub Abstract:
Background
The trigeminal nerve is the largest cranial nerve and functions in somatosensation. Cell bodies of this nerve are... Delivery Method:
electroporation Organism or Cell Type:
chick trigeminal placode cells Citation Extract: Hines MA, Taneyhill LA. Elp1 function in placode-derived neurons is critical for proper trigeminal ganglion development. Dev Dyn. 2024 Oct 9. doi: 10.1002/dvdy.749. Epub ahead of print. PMID: 39381860. |
A group 3 medulloblastoma stem cell program is maintained by OTX2-mediated alternative splicing
Citation:
Nat Cell Biol. 2024 Jul 18. doi: 10.1038/s41556-024-01460-5. Epub ahead of print. PMID: 39025928. Epub:
Not Epub Abstract:
OTX2 is a transcription factor and known driver in medulloblastoma (MB), where it is amplified in a subset of tumours and... Delivery Method:
Pre-treat cells then cerebellum injection into NOD-SCID mice Organism or Cell Type:
HDMB03 and MB3W1 cell line-derived tumourspheres Citation Extract: Saulnier O, Zagozewski J, Liang L, Hendrikse LD, Layug P, Gordon V, Aldinger KA, Haldipur P, Borlase S, Coudière-Morrison L, Cai T, Martell E, Gonzales NM, Palidwor G, Porter CJ, Richard S, Sharif T, Millen KJ, Doble BW, Taylor MD, Werbowetski-Ogilvie TE. A group 3 medulloblastoma stem cell program is maintained by OTX2-mediated alternative splicing. Nat Cell Biol. 2024 Jul 18. doi: 10.1038/s41556-024-01460-5. Epub ahead of print. PMID: 39025928.. |
The Usefulness of Determining Plasma and Tissue Concentrations of Phosphorodiamidate Morpholino Oligonucleotides to Estimate Their Efficacy in Duchenne Muscular Dystrophy Patients
Citation:
Drug Metab Dispos. 2024 Aug 14;52(9):1029-1036. doi: 10.1124/dmd.124.001806. PMID: 38991781 Epub:
Not Epub Abstract:
Currently four kinds of phosphorodiamidate morpholino oligomers (PMOs) such as viltolarsen have been approved for the treatment... Delivery Method:
i.v. bolus injection (mice), i.v. infusion and bolus injection (monkey) Organism or Cell Type:
mice (mdx): C57BL/10ScSn-DmdmdxJ, Cynomolgus monkeys Citation Extract: Imai S, Watanabe N, Tone Y, Mitamura R, Mori J, Kameyama T, Yamada T, Kusano K. The Usefulness of Determining Plasma and Tissue Concentrations of Phosphorodiamidate Morpholino Oligonucleotides to Estimate Their Efficacy in Duchenne Muscular Dystrophy Patients. Drug Metab Dispos. 2024 Aug 14;52(9):1029-1036. doi: 10.1124/dmd.124.001806. PMID: 38991781. |
Biallelic variants in POPDC2 cause a novel autosomal recessive syndrome presenting with cardiac conduction defects and variable hypertrophic cardiomyopathy
Citation:
medRxiv [preprint] 2024.07.04.24309755 Epub:
Not Epub Abstract:
POPDC2 encodes for the Popeye domain-containing protein 2 which has an important role in cardiac pacemaking and conduction, due... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nicastro M, Vermeer Alexa MC, Postema PG,Tadros R, Bowling FZ, Aegisdottir, HM, et al.. Biallelic variants in POPDC2 cause a novel autosomal recessive syndrome presenting with cardiac conduction defects and variable hypertrophic cardiomyopathy. medRxiv [preprint] 2024.07.04.24309755. |