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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12454 scientific papers returned from the database with the search filters currently being used below.

SIRT2 deacetylates and inhibits the peroxidase activity of peroxiredoxin-1 to sensitize breast cancer cells to oxidant stress inducing agents

Authors:
Fiskus W, Coothankandaswamy V, Chen J, Ma H, Ha K, Saenz DT, Krieger SS, Mill CP, Sun B, Huang P, Mumm JS, Melnick A, Bhalla KN
Citation:
Cancer Res. 2016 Aug 8. pii: canres.0126.2016. [Epub ahead of print] doi:10.1158/0008-5472.CAN-16-0126
Epub:
Yes
Abstract:
SIRT2 is a protein deacetylase with tumor suppressor activity in breast and liver tumors where it is mutated, however, the...
Link:
http://cancerres.aacrjournals.org/content/early/2016/09/07/0008-5472.CAN-16-0126
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fiskus W, Coothankandaswamy V, Chen J, Ma H, Ha K, Saenz DT, Krieger SS, Mill CP, Sun B, Huang P, Mumm JS, Melnick A, Bhalla KN. SIRT2 deacetylates and inhibits the peroxidase activity of peroxiredoxin-1 to sensitize breast cancer cells to oxidant stress inducing agents. Cancer Res. 2016 Aug 8. pii: canres.0126.2016. [Epub ahead of print] doi:10.1158/0008-5472.CAN-16-0126.

Experimental Dissection of Metalloproteinase Inhibition-Mediated and Toxic Effects of Phenanthroline on Zebrafish Development

Authors:
Ellis TR, Crawford BD
Citation:
Int J Mol Sci. 2016;17(9):1503. doi:10.3390/ijms17091503
Epub:
Not Epub
Abstract:
Metalloproteinases are zinc-dependent endopeptidases that function as primary effectors of tissue remodeling, cell-signaling,...
Link:
http://www.mdpi.com/1422-0067/17/9/1503/htm
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ellis TR, Crawford BD. Experimental Dissection of Metalloproteinase Inhibition-Mediated and Toxic Effects of Phenanthroline on Zebrafish Development. Int J Mol Sci. 2016;17(9):1503. doi:10.3390/ijms17091503.

Steering cell migration by alternating blebs and actin-rich protrusions

Authors:
Diz-Muñoz A, Romanczuk P, Yu W, Bergert M, Ivanovitch K, Salbreux G, Heisenberg CP, Paluch EK
Citation:
BMC Biol. 2016 Sep 2;14:74. doi: 10.1186/s12915-016-0294-x
Epub:
Not Epub
Abstract:
BACKGROUND: High directional persistence is often assumed to enhance the efficiency of chemotactic migration. Yet, cells in...
Link:
http://bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0294-x
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Diz-Muñoz A, Romanczuk P, Yu W, Bergert M, Ivanovitch K, Salbreux G, Heisenberg CP, Paluch EK. Steering cell migration by alternating blebs and actin-rich protrusions. BMC Biol. 2016 Sep 2;14:74. doi: 10.1186/s12915-016-0294-x.

Chromosome 5q33 deletions associated with congenital heart defects

Authors:
Starkovich M, Lalani SR, Mercer CL, Scott DA
Citation:
Am J Med Genet A. 2016 Sep 2. doi: 10.1002/ajmg.a.37957. [Epub ahead of print]
Epub:
Yes
Abstract:
Congenital heart defects (CHD) are present in over 1% of all newborns and are the leading cause of birth-defect-related deaths...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/ajmg.a.37957/abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Starkovich M, Lalani SR, Mercer CL, Scott DA. Chromosome 5q33 deletions associated with congenital heart defects. Am J Med Genet A. 2016 Sep 2. doi: 10.1002/ajmg.a.37957. [Epub ahead of print].

Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at Cilia

Authors:
del Viso F, Huang F, Myers J, Chalfant M, Zhang Y, Reza N, Bewersdorf J, Lusk CP, Khokha MK
Citation:
Dev Cell. 2016;[Epub ahead of print]. doi:10.1016/j.devcel.2016.08.002
Epub:
Yes
Abstract:
Human genomics is identifying candidate genes for congenital heart disease (CHD), but discovering the underlying mechanisms...
Link:
http://www.cell.com/developmental-cell/abstract/S1534-5807(16)30553-6
Organism or Cell Type:
zebrafish
Citation Extract:
del Viso F, Huang F, Myers J, Chalfant M, Zhang Y, Reza N, Bewersdorf J, Lusk CP, Khokha MK. Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at Cilia. Dev Cell. 2016;[Epub ahead of print]. doi:10.1016/j.devcel.2016.08.002.

Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis

Authors:
Cox AG, Tsomides A, Kim AJ, Saunders D, Hwang KL, Evason KJ, Heidel J, Brown KK, Yuan M, Lien EC, Lee BC, Nissim S, Dickinson B, Chhangawala S, Changh CJ, Asara JM, Houvras Y, Gladyshev VN, Goessling W.
Citation:
Proc Natl Acad Sci USA. 2016;[Epub ahead of print] doi:10.1073/pnas.1600204113
Epub:
Yes
Abstract:
Selenium, an essential micronutrient known for its cancer prevention properties, is incorporated into a class of selenocysteine...
Link:
http://www.pnas.org/content/early/2016/08/31/1600204113.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Cox AG, Tsomides A, Kim AJ, Saunders D, Hwang KL, Evason KJ, Heidel J, Brown KK, Yuan M, Lien EC, Lee BC, Nissim S, Dickinson B, Chhangawala S, Changh CJ, Asara JM, Houvras Y, Gladyshev VN, Goessling W.. Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis. Proc Natl Acad Sci USA. 2016;[Epub ahead of print] doi:10.1073/pnas.1600204113.

Morphology and Gene Expression Screening with Morpholinos in Zebrafish Embryos

Authors:
Tseng LC, Tang CH, Jiang YJ
Citation:
Methods Mol Biol. 2016;1470:213-24. doi: 10.1007/978-1-4939-6337-9_17
Epub:
Not Epub
Abstract:
High-throughput screening with a loss-of-function strategy is a logical and efficient way to identify novel genes involved in...
Link:
http://link.springer.com/protocol/10.1007%2F978-1-4939-6337-9_17
Organism or Cell Type:
zebrafish
Citation Extract:
Tseng LC, Tang CH, Jiang YJ. Morphology and Gene Expression Screening with Morpholinos in Zebrafish Embryos. Methods Mol Biol. 2016;1470:213-24. doi: 10.1007/978-1-4939-6337-9_17.

Identification of p53-target genes in Danio rerio

Authors:
Mandriani B, Castellana S, Rinaldi C, Manzoni M, Venuto S, Rodriguez-Aznar E, Galceran J, Nieto MA, Borsani G, Monti E, Mazza T, Merla G, Micale L
Citation:
Sci Rep. 2016;6:32474. doi:10.1038/srep32474
Epub:
Not Epub
Abstract:
To orchestrate the genomic response to cellular stress signals, p53 recognizes and binds to DNA containing specific and well-...
Link:
http://www.nature.com/articles/srep32474
Organism or Cell Type:
zebrafish
Citation Extract:
Mandriani B, Castellana S, Rinaldi C, Manzoni M, Venuto S, Rodriguez-Aznar E, Galceran J, Nieto MA, Borsani G, Monti E, Mazza T, Merla G, Micale L. Identification of p53-target genes in Danio rerio. Sci Rep. 2016;6:32474. doi:10.1038/srep32474.

Role of morphine, miR-212/132 and mu opioid receptor in the regulation of Bdnf in zebrafish embryos

Authors:
Jimenez-Gonzalez A, García-Concejo A, López-Benito S, Gonzalez-Nunez V, Arévalo JC, Rodriguez RE
Citation:
Biochim Biophys Acta. 2016 Jun;1860(6):1308-16. doi: 10.1016/j.bbagen.2016.03.001. Epub 2016 Mar 4
Epub:
Not Epub
Abstract:
BACKGROUND: Morphine is one of the first-line therapies for the treatment of pain despite its secondary effects. It modifies...
Link:
http://www.sciencedirect.com/science/article/pii/S030441651630054X
Organism or Cell Type:
zebrafish
Citation Extract:
Jimenez-Gonzalez A, García-Concejo A, López-Benito S, Gonzalez-Nunez V, Arévalo JC, Rodriguez RE. Role of morphine, miR-212/132 and mu opioid receptor in the regulation of Bdnf in zebrafish embryos. Biochim Biophys Acta. 2016 Jun;1860(6):1308-16. doi: 10.1016/j.bbagen.2016.03.001. Epub 2016 Mar 4.

Lxr regulates lipid metabolic and visual perception pathways during zebrafish development

Authors:
Pinto CL, Kalasekar SM, McCollum CW, Riu A, Jonsson P, Lopez J, Swindell EC, Bouhlatouf A, Balaguer P, Bondesson M, Gustafsson JÅ
Citation:
Mol Cell Endocrinol. 2016 Jan 5;419:29-43. doi: 10.1016/j.mce.2015.09.030. Epub 2015 Sep 30
Epub:
Not Epub
Abstract:
The Liver X Receptors (LXRs) play important roles in multiple metabolic pathways, including fatty acid, cholesterol,...
Link:
http://www.sciencedirect.com/science/article/pii/S0303720715300964
Organism or Cell Type:
zebrafish
Citation Extract:
Pinto CL, Kalasekar SM, McCollum CW, Riu A, Jonsson P, Lopez J, Swindell EC, Bouhlatouf A, Balaguer P, Bondesson M, Gustafsson JÅ. Lxr regulates lipid metabolic and visual perception pathways during zebrafish development. Mol Cell Endocrinol. 2016 Jan 5;419:29-43. doi: 10.1016/j.mce.2015.09.030. Epub 2015 Sep 30.

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