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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12455 scientific papers returned from the database with the search filters currently being used below.

Copper supplementation restores cytochrome c oxidase assembly defect in a mitochondrial disease model of COA6 deficiency

Authors:
Ghosh A, Trivedi PP, Timbalia SA, Griffin AT, Rahn JJ, Chan SS, Gohil VM
Citation:
Hum Mol Genet. 2014 Feb 18. [Epub ahead of print]
Epub:
Yes
Abstract:
Mitochondrial respiratory chain biogenesis is orchestrated by hundreds of assembly factors, many of which are yet to be...
Link:
http://hmg.oxfordjournals.org/content/early/2014/02/18/hmg.ddu069.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Ghosh A, Trivedi PP, Timbalia SA, Griffin AT, Rahn JJ, Chan SS, Gohil VM. Copper supplementation restores cytochrome c oxidase assembly defect in a mitochondrial disease model of COA6 deficiency. Hum Mol Genet. 2014 Feb 18. [Epub ahead of print].

Functional modelling of a novel mutation in BBS5

Authors:
Al-Hamed MH, van Lennep C, Hynes AM, Chrystal P, Eley L, Al-Fadhly F, El Sayed E, Simms RJ, Meyer B, Sayer JA
Citation:
Cilia. 2014;3(3) doi:10.1186/2046-2530-3-3
Epub:
Not Epub
Abstract:
Background: Bardet-Biedl syndrome (BBS) is an autosomal recessive ciliopathy disorder with 18 known causative genes (BBS1-18)....
Link:
http://www.ciliajournal.com/content/3/1/3
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Al-Hamed MH, van Lennep C, Hynes AM, Chrystal P, Eley L, Al-Fadhly F, El Sayed E, Simms RJ, Meyer B, Sayer JA. Functional modelling of a novel mutation in BBS5. Cilia. 2014;3(3) doi:10.1186/2046-2530-3-3.

Inhibition of SULT4A1 Expression Induces Up-regulation of Phototransduction Gene Expression in 72 Hours Post Fertilization Zebrafish Larvae

Authors:
Crittenden F, Thomas H, Ethen CM, Wu ZL, Chen D, Kraft T, Parant J, Falany CN
Citation:
Drug Metab Dispos. 2014 Feb 19. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Sulfotransferase (SULT) 4A1 is an orphan enzyme that shares distinct structure and sequence similarities with other cytosolic...
Link:
http://dmd.aspetjournals.org/content/early/2014/02/19/dmd.114.057042.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Crittenden F, Thomas H, Ethen CM, Wu ZL, Chen D, Kraft T, Parant J, Falany CN. Inhibition of SULT4A1 Expression Induces Up-regulation of Phototransduction Gene Expression in 72 Hours Post Fertilization Zebrafish Larvae. Drug Metab Dispos. 2014 Feb 19. [Epub ahead of print].

Microtubule-associated protein 9 (Map9/Asap) is required for the early steps of zebrafish development

Authors:
Fontenille L, Rouquier S, Lutfalla G, Giorgi D
Citation:
Cell Cycle. 2014 Feb 4;13(7). [Epub ahead of print]
Epub:
Not Epub
Abstract:
Microtubules are structural components of the cell cytoskeleton and key factors for mitosis and ciliogenesis in eukaryotes. The...
Link:
https://www.landesbioscience.com/journals/cc/article/27944/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fontenille L, Rouquier S, Lutfalla G, Giorgi D. Microtubule-associated protein 9 (Map9/Asap) is required for the early steps of zebrafish development. Cell Cycle. 2014 Feb 4;13(7). [Epub ahead of print].

Transcription factor AP2 epsilon (Tfap2e) regulates neural crest specification in Xenopus

Authors:
Hong C-S, Devotta A, Lee Y-H, Park B-Y, Saint-Jeannet J-P
Citation:
Devel Neurobio. 2014;[Epub ahead of print] doi:10.1002/dneu.22173
Epub:
Yes
Abstract:
Transcription factors Pax3 and Zic1 are two important regulators of cell fate decision at the neural plate border, where they...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dneu.22173/abstract
Organism or Cell Type:
Xenopus
Citation Extract:
Hong C-S, Devotta A, Lee Y-H, Park B-Y, Saint-Jeannet J-P. Transcription factor AP2 epsilon (Tfap2e) regulates neural crest specification in Xenopus. Devel Neurobio. 2014;[Epub ahead of print] doi:10.1002/dneu.22173.

Pax6 regulates the formation of the habenular nuclei by controlling the temporospatial expression of Shh in the diencephalon in vertebrates

Authors:
Chatterjee M, Guo Q, Weber S, Scholpp S, Li JY
Citation:
BMC Biol. 2014 Feb 14;12(1):13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: The habenula and the thalamus are two critical nodes in the forebrain circuitry and they connect the midbrain and...
Link:
http://www.biomedcentral.com/1741-7007/12/13/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chatterjee M, Guo Q, Weber S, Scholpp S, Li JY. Pax6 regulates the formation of the habenular nuclei by controlling the temporospatial expression of Shh in the diencephalon in vertebrates. BMC Biol. 2014 Feb 14;12(1):13. [Epub ahead of print].

Assessment of RT-qPCR Normalization Strategies for Accurate Quantification of Extracellular microRNAs in Murine Serum

Authors:
Roberts TC, Coenen-Stass AML, Wood MJA
Citation:
PLoS ONE. 2014;9(2):e89237. doi:10.1371/journal.pone.0089237
Epub:
Not Epub
Abstract:
Extracellular microRNAs (miRNAs) are under investigation as minimally-invasive biomarkers for a wide range of disease...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0089237
Delivery Method:
peptide-linked
Organism or Cell Type:
mouse
Citation Extract:
Roberts TC, Coenen-Stass AML, Wood MJA. Assessment of RT-qPCR Normalization Strategies for Accurate Quantification of Extracellular microRNAs in Murine Serum. PLoS ONE. 2014;9(2):e89237. doi:10.1371/journal.pone.0089237.

Eph-Ephrin signaling and focal adhesion kinase regulate actomyosin-dependent apical constriction of ciliary band cells

Authors:
Krupke OA, Burke RD
Citation:
Development. 2014 Mar;141(5):1075-84. doi: 10.1242/dev.100123
Epub:
Not Epub
Abstract:
Apical constriction typically accompanies inward folding of an epithelial sheet. In recent years there has been progress in...
Link:
http://dev.biologists.org/content/141/5/1075.abstract
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Krupke OA, Burke RD. Eph-Ephrin signaling and focal adhesion kinase regulate actomyosin-dependent apical constriction of ciliary band cells. Development. 2014 Mar;141(5):1075-84. doi: 10.1242/dev.100123.

Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2

Authors:
Zhou Q, Yang D, Ombrello AK, Zavialov AV, Toro C, Zavialov AV, Stone DL, Chae JJ, Rosenzweig SD, Bishop K, Barron KS, Kuehn HS, Hoffmann P, Negro A, Tsai WL, Cowen EW, Pei W, Milner JD, Silvin C, Heller T, Chin DT, Patronas NJ, Barber JS, Lee C-CR, Wood GM, Ling A, Kelly SJ, Kleiner DE, Mullikin JC, Ganson NJ, Kong HH, Hambleton S, Candotti F, Quezado MM, Calvo KR, Alao H, Barham BK, Jones A, Meschia JF, Worrall BB, Kasner SE, Rich SS, Goldbach-Mansky R, Abinun M, Chalom E, Gotte AC, Punaro M, Pascual V, Verbsky JW, Torgerson TR, Singer NG, Gershon TR, Ozen S, Karadag O, Fleisher TA, Remmers EF, Burgess SM, Moir SL, Gadina M, Sood R, Hershfield MS, Boehm M, Kastner DL, Aksentijevich I
Citation:
N Engl J Med. 2014 Mar 6;370(10):911-20. doi: 10.1056/NEJMoa1307361. Epub 2014 Feb 19.
Epub:
Yes
Abstract:
Background: We observed a syndrome of intermittent fevers, early-onset lacunar strokes and other neurovascular manifestations,...
Link:
http://www.nejm.org/doi/full/10.1056/NEJMoa1307361#t=abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou Q, Yang D, Ombrello AK, Zavialov AV, Toro C, Zavialov AV, Stone DL, Chae JJ, Rosenzweig SD, Bishop K, Barron KS, Kuehn HS, Hoffmann P, Negro A, Tsai WL, Cowen EW, Pei W, Milner JD, Silvin C, Heller T, Chin DT, Patronas NJ, Barber JS, Lee C-CR, Wood GM, Ling A, Kelly SJ, Kleiner DE, Mullikin JC, Ganson NJ, Kong HH, Hambleton S, Candotti F, Quezado MM, Calvo KR, Alao H, Barham BK, Jones A, Meschia JF, Worrall BB, Kasner SE, Rich SS, Goldbach-Mansky R, Abinun M, Chalom E, Gotte AC, Punaro M, Pascual V, Verbsky JW, Torgerson TR, Singer NG, Gershon TR, Ozen S, Karadag O, Fleisher TA, Remmers EF, Burgess SM, Moir SL, Gadina M, Sood R, Hershfield MS, Boehm M, Kastner DL, Aksentijevich I. Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2. N Engl J Med. 2014 Mar 6;370(10):911-20. doi: 10.1056/NEJMoa1307361. Epub 2014 Feb 19..

Two independent transcription initiation codes overlap on vertebrate core promoters

Authors:
Haberle V, Li N, Hadzhiev Y, Plessy C, Previti C, Nepal C, Gehrig J, Dong X, Akalin A, Suzuki AM, van Ijcken WF, Armant O, Ferg M, Strähle U, Carninci P, Müller F, Lenhard B
Citation:
Nature. 2014 Feb 16. doi: 10.1038/nature12974. [Epub ahead of print]
Epub:
Yes
Abstract:
A core promoter is a stretch of DNA surrounding the transcription start site (TSS) that integrates regulatory inputs and...
Link:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12974.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Haberle V, Li N, Hadzhiev Y, Plessy C, Previti C, Nepal C, Gehrig J, Dong X, Akalin A, Suzuki AM, van Ijcken WF, Armant O, Ferg M, Strähle U, Carninci P, Müller F, Lenhard B. Two independent transcription initiation codes overlap on vertebrate core promoters. Nature. 2014 Feb 16. doi: 10.1038/nature12974. [Epub ahead of print].

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