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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12483 scientific papers returned from the database with the search filters currently being used below.
There are 12483 scientific papers returned from the database with the search filters currently being used below.
Evaluation of the Effect of 2’-O-Methyl, Fluoro Hexitol, Bicyclo and Morpholino Nucleic Acid Modifications on Potency of GalNAc Conjugated Antisense Oligonucleotides in Mice
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Citation:
Bioorg Med Chem Lett. 2018;[Epub ahead of print] doi:10.1016/j.bmcl.2018.10.011 Epub:
Not Epub Abstract:
The potency of antisense oligonucleotide (ASO) drugs has significantly improved in the clinic after exploiting... Delivery Method:
GalNAc-linked Organism or Cell Type:
mice Citation Extract: Prakash TP, Yu J, Kinberger GA, Low A, Jackson M, Rigo F, Swayze EE, Seth PP. Evaluation of the Effect of 2’-O-Methyl, Fluoro Hexitol, Bicyclo and Morpholino Nucleic Acid Modifications on Potency of GalNAc Conjugated Antisense Oligonucleotides in Mice. Bioorg Med Chem Lett. 2018;[Epub ahead of print] doi:10.1016/j.bmcl.2018.10.011. |
ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis
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Citation:
Sci Translat Med. 2018;10(462):eaam7486 doi:10.1126/scitranslmed.aam7486 Epub:
Not Epub Abstract:
Developing and mature chondrocytes constantly interact with and remodel the surrounding extracellular matrix (ECM). Recent... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Song EK, Jeon J, Jang DG, Kim HE, Sim HJ, Kwon KY, Medina-Ruiz S, Jang H-J, Lee AR, Rho JG, Lee H-S, Kim SJ, Park CY, Myung K, Kim W, Kwon T, Yang S, Park TJ. ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis. Sci Translat Med. 2018;10(462):eaam7486 doi:10.1126/scitranslmed.aam7486 . |
Evaluation of the estrogen receptor alpha as a possible target of bifenthrin effects in the estrogenic and dopaminergic signaling pathways in zebrafish embryos
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Citation:
Sci Total Environ. 2019;651(pt.2):2424-2431. doi:10.1016/j.scitotenv.2018.10.079 Epub:
Not Epub Abstract:
Bifenthrin (BF) is a pyrethroid insecticide widely used in urban and agricultural applications. Previous studies in embryos of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Becker Bertotto L, Dasgupta S, Vliet S, Dudley S, Gan J, Volz DC, Schlenk D. Evaluation of the estrogen receptor alpha as a possible target of bifenthrin effects in the estrogenic and dopaminergic signaling pathways in zebrafish embryos. Sci Total Environ. 2019;651(pt.2):2424-2431. doi:10.1016/j.scitotenv.2018.10.079. |
CAV1 regulates primordial follicle formation via the Notch2 signalling pathway and is associated with premature ovarian insufficiency in humans
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Citation:
Hum Reprod. 2018;dey299. doi:10.1093/humrep/dey299 Epub:
Not Epub Abstract:
STUDY QUESTION: What is the function of CAV1 in folliculogenesis and female reproduction?
SUMMARY ANSWER: CAV1 regulates... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mouse ovary Citation Extract: Huang K, Dang Y, Zhang P, Shen C, Sui X, Xia G, Qin Y, Jiao X, Wang C, Huo R, Chen Z-J. CAV1 regulates primordial follicle formation via the Notch2 signalling pathway and is associated with premature ovarian insufficiency in humans. Hum Reprod. 2018;dey299. doi:10.1093/humrep/dey299. |
The Ric-8A/Gα13/FAK signaling cascade controls focal adhesion formation during neural crest cell migration
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Citation:
Development. 2018 Oct 8. pii: dev.164269. doi: 10.1242/dev.164269. [Epub ahead of print] Epub:
Yes Abstract:
Ric-8A is a pleiotropic guanine nucleotide exchange factor involved the activation of various heterotrimeric G protein pathways... Citation Extract: Toro-Tapia G, Villaseca S, Beyer A, Roycroft A, Marcellini S, Mayor R, Torrejón M. The Ric-8A/Gα13/FAK signaling cascade controls focal adhesion formation during neural crest cell migration. Development. 2018 Oct 8. pii: dev.164269. doi: 10.1242/dev.164269. [Epub ahead of print]. |
Generation of animal form by the Chordin/Tolloid/BMP gradient: 100 years after D'Arcy Thompson
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Citation:
Dev Growth Differ. 2017 Sep;59(7):580-592. doi: 10.1111/dgd.12388. Epub 2017 Aug 16 Epub:
Not Epub Abstract:
The classic book "On Growth and Form" by naturalist D'Arcy Thompson was published 100 years ago. To celebrate... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: De Robertis EM, Moriyama Y, Colozza G. Generation of animal form by the Chordin/Tolloid/BMP gradient: 100 years after D'Arcy Thompson. Dev Growth Differ. 2017 Sep;59(7):580-592. doi: 10.1111/dgd.12388. Epub 2017 Aug 16. |
The Evolutionarily Conserved Cassette Exon 7b Drives ERG's Oncogenic Properties
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Citation:
Transl Oncol. 2018;12(1):134-42. doi:10.1016/j.tranon.2018.09.001 Epub:
Not Epub Abstract:
The oncogene ERG encodes an ETS family transcription factor and is implicated in blood, vascular, and bone development and in... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: MG63 ( human osteoblast-like osteosarcoma) and VCaP (human prostate cancer vertebral metastasis) Citation Extract: Jumbe SL, Porazinski SR, Oltean S, Mansell JP, Vahabi B, Wilson ID, Ladomery MR. The Evolutionarily Conserved Cassette Exon 7b Drives ERG's Oncogenic Properties. Transl Oncol. 2018;12(1):134-42. doi:10.1016/j.tranon.2018.09.001. |
Intestinal microbiome adjusts the innate immune setpoint during colonization through negative regulation of MyD88
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Citation:
Nat Commun. 2018 Oct 5;9(1):4099. doi: 10.1038/s41467-018-06658-4 Epub:
Not Epub Abstract:
Host pathways mediating changes in immune states elicited by intestinal microbial colonization are incompletely characterized.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Koch BEV, Yang S, Lamers G, Stougaard J, Spaink HP. Intestinal microbiome adjusts the innate immune setpoint during colonization through negative regulation of MyD88. Nat Commun. 2018 Oct 5;9(1):4099. doi: 10.1038/s41467-018-06658-4. |
Fam46a regulates BMP-dependent pre-placodal ectoderm differentiation in Xenopus
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Citation:
Development. 2018:dev.166710 doi: 10.1242/dev.166710 Epub:
Not Epub Abstract:
The pre-placodal ectoderm (PPE) is a specialized ectodermal region which gives rise to the sensory organs and other systems.... Organism or Cell Type:
Xenopus laevis Citation Extract: Watanabe T, Yamamoto T, Tsukano K, Hirano S, Horikawa A, Michiue T. Fam46a regulates BMP-dependent pre-placodal ectoderm differentiation in Xenopus. Development. 2018:dev.166710 doi: 10.1242/dev.166710. |
4.1Ba is necessary for glutamatergic synapse formation in the sensorimotor circuit of developing zebrafish
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Citation:
PLoS One. 2018 Oct 4;13(10):e0205255. doi: 10.1371/journal.pone.0205255 Epub:
Not Epub Abstract:
During the process of synapse formation, thousands of proteins assemble at prospective sites of cell-cell communication.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fierro J Jr, Haynes DR, Washbourne P. 4.1Ba is necessary for glutamatergic synapse formation in the sensorimotor circuit of developing zebrafish. PLoS One. 2018 Oct 4;13(10):e0205255. doi: 10.1371/journal.pone.0205255. |