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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12455 scientific papers returned from the database with the search filters currently being used below.

Identification of promoter elements responsible for gonad-specific expression of zebrafish Deadend and its application to ovarian germ cell derivation

Authors:
Wong T-T, Tesfamichael A, Collodi P
Citation:
Int J Dev Biol. 2013;[Epub ahead of print] doi:10.1387/ijdb.120234tw
Epub:
Not Epub
Abstract:
We discovered that a 150-bp region of zebrafish deadend (dnd) spanning the translation start codon, exon 1 and part of intron 1...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wong T-T, Tesfamichael A, Collodi P. Identification of promoter elements responsible for gonad-specific expression of zebrafish Deadend and its application to ovarian germ cell derivation. Int J Dev Biol. 2013;[Epub ahead of print] doi:10.1387/ijdb.120234tw.

Identification of ZBP-89 as a Novel GATA-1 Associated Transcription Factor Involved in Megakaryocytic and Erythroid Development

Authors:
Woo AJ, Moran TB, Schindler Y, Choe SK, Langer NB, Sullivan MR, Fujiwara Y, Paw BH, Cantor AB
Citation:
Mol Cell Biol. 2008 Apr;28(8):2675-89. Epub 2008 Feb 4.
Epub:
Not Epub
Abstract:
A complete understanding of the transcriptional regulation of developmental lineages requires that all relevant factors be...
Organism or Cell Type:
zebrafish
Citation Extract:
Woo AJ, Moran TB, Schindler Y, Choe SK, Langer NB, Sullivan MR, Fujiwara Y, Paw BH, Cantor AB. Identification of ZBP-89 as a Novel GATA-1 Associated Transcription Factor Involved in Megakaryocytic and Erythroid Development. Mol Cell Biol. 2008 Apr;28(8):2675-89. Epub 2008 Feb 4..

Kermit 2/XGIPC, an IGF1 receptor interacting protein, is required for IGF signaling in Xenopus eye development

Authors:
Wu J, O'Donnell M, Gitler AD, Klein PS
Citation:
Development. 2006 Sep;133(18):3651-60. Epub 2006 Aug 16
Epub:
Not Epub
Abstract:
GIPC is a PDZ-domain-containing protein identified in vertebrate and invertebrate organisms through its interaction with a...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Wu J, O'Donnell M, Gitler AD, Klein PS. Kermit 2/XGIPC, an IGF1 receptor interacting protein, is required for IGF signaling in Xenopus eye development. Development. 2006 Sep;133(18):3651-60. Epub 2006 Aug 16.

Long-Term Rescue of Dystrophin Expression and Improvement in Muscle Pathology and Function in Dystrophic mdx Mice by Peptide-Conjugated Morpholino

Authors:
Wu B, Lu P, Cloer C, Shaban M, Grewal S, Milazi S, Shah SN, Moulton HM, Lu QL
Citation:
Am J Pathol. 2012 Aug;181(2):392-400. doi: 10.1016/j.ajpath.2012.04.006. Epub 2012 Jun 7.
Epub:
Not Epub
Abstract:
Exon skipping is capable of correcting frameshift and nonsense mutations in Duchenne muscular dystrophy (DMD). Phase 2 clinical...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice, mdx
Citation Extract:
Wu B, Lu P, Cloer C, Shaban M, Grewal S, Milazi S, Shah SN, Moulton HM, Lu QL. Long-Term Rescue of Dystrophin Expression and Improvement in Muscle Pathology and Function in Dystrophic mdx Mice by Peptide-Conjugated Morpholino. Am J Pathol. 2012 Aug;181(2):392-400. doi: 10.1016/j.ajpath.2012.04.006. Epub 2012 Jun 7..

Mycophenolic acid is a potent inhibitor of angiogenesis

Authors:
Wu X, Zhong H, Song J, Damoiseaux R, Yang Z, Lin S
Citation:
Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2414-6
Epub:
Not Epub
Abstract:
No abstract available
Citation Extract:
Wu X, Zhong H, Song J, Damoiseaux R, Yang Z, Lin S. Mycophenolic acid is a potent inhibitor of angiogenesis. Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2414-6.

Myosin-10 and actin filaments are essential for mitotic spindle function

Authors:
Woolner S, O'Brien LL, Wiese C, Bement WM
Citation:
J Cell Biol. 2008 Jul 14;182(1):77-88. Epub 2008 Jul 7.
Epub:
Not Epub
Abstract:
Mitotic spindles are microtubule-based structures responsible for chromosome partitioning during cell division. Although the...
Citation Extract:
Woolner S, O'Brien LL, Wiese C, Bement WM. Myosin-10 and actin filaments are essential for mitotic spindle function. J Cell Biol. 2008 Jul 14;182(1):77-88. Epub 2008 Jul 7..

Naip5 Affects Host Susceptibility to the Intracellular Pathogen Legionella pneumophila

Authors:
Wright EK, Goodart SA, Growney JD, Hadinoto V, Endrizzi MG, Long EM, Sadigh K, Abney AL, Bernstein-Hanley I, Dietrich WF
Citation:
Curr Biol. 2003 Jan 8;13(1):27-36
Epub:
Not Epub
Abstract:
BACKGROUND: Legionella pneumophila is a gram-negative bacterial pathogen that is the cause of Legionnaires' Disease....
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: primary macrophages
Citation Extract:
Wright EK, Goodart SA, Growney JD, Hadinoto V, Endrizzi MG, Long EM, Sadigh K, Abney AL, Bernstein-Hanley I, Dietrich WF. Naip5 Affects Host Susceptibility to the Intracellular Pathogen Legionella pneumophila. Curr Biol. 2003 Jan 8;13(1):27-36.

Nodal signaling regulates endodermal cell motility and actin dynamics via Rac1 and Prex1

Authors:
Woo S, Housley MP, Weiner OD, Stainier DYR
Citation:
J Cell Biol. 2012;198(5)941-52. doi:10.1083/jcb.201203012
Epub:
Not Epub
Abstract:
Embryo morphogenesis is driven by dynamic cell behaviors, including migration, that are coordinated with fate specification and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Woo S, Housley MP, Weiner OD, Stainier DYR. Nodal signaling regulates endodermal cell motility and actin dynamics via Rac1 and Prex1. J Cell Biol. 2012;198(5)941-52. doi:10.1083/jcb.201203012.

Octa-guanidine Morpholino Restores Dystrophin Expression in Cardiac and Skeletal Muscles and Ameliorates Pathology in Dystrophic mdx Mice

Authors:
Wu B, Li Y, Morcos PA, Doran TJ, Lu P, Lu QL
Citation:
Mol Ther. 2009 May;17(5):864-71. Epub 2009 Mar 10
Epub:
Not Epub
Abstract:
Steric-block antisense oligonucleotides (AONs) are able to target RNAs for destruction and splicing alteration. Reading frame...
Delivery Method:
Vivo-Morpholino (Vivo-Porter moiety)
Organism or Cell Type:
mice, mdx
Citation Extract:
Wu B, Li Y, Morcos PA, Doran TJ, Lu P, Lu QL. Octa-guanidine Morpholino Restores Dystrophin Expression in Cardiac and Skeletal Muscles and Ameliorates Pathology in Dystrophic mdx Mice. Mol Ther. 2009 May;17(5):864-71. Epub 2009 Mar 10.

One-year Treatment of Morpholino Antisense Oligomer Improves Skeletal and Cardiac Muscle Functions in Dystrophic mdx Mice

Authors:
Wu B, Xiao B, Cloer C, Shaban M, Sali A, Lu P, Li J, Nagaraju K, Xiao X, Lu QL
Citation:
Mol Ther. 2011;19(3):576-83. doi:10.1038/mt.2010.288
Epub:
Not Epub
Abstract:
Antisense therapy has been successful to skip targeted dystrophin exon with correction of frameshift and nonsense mutations of...
Link:
http://www.sciencedirect.com/science/article/pii/S1525001616304063
Delivery Method:
Injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Wu B, Xiao B, Cloer C, Shaban M, Sali A, Lu P, Li J, Nagaraju K, Xiao X, Lu QL. One-year Treatment of Morpholino Antisense Oligomer Improves Skeletal and Cardiac Muscle Functions in Dystrophic mdx Mice. Mol Ther. 2011;19(3):576-83. doi:10.1038/mt.2010.288.

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